Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

381 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCY1 adenylate cyclase 1 (brain)
ADGRG7 adhesion G protein-coupled receptor G7
ADGRL2 adhesion G protein-coupled receptor L2
AFAP1 actin filament associated protein 1
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGO2 argonaute RISC catalytic component 2
AGTPBP1 ATP/GTP binding protein 1
AKAP13 A kinase (PRKA) anchor protein 13
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMOTL1 angiomotin like 1
ANKRD50 ankyrin repeat domain 50
ANO2 anoctamin 2, calcium activated chloride channel
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLNR apelin receptor
APOL5 apolipoprotein L, 5
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP31 Rho GTPase activating protein 31
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL15 ADP-ribosylation factor-like 15
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATXN3 ataxin 3
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BAHCC1 BAH domain and coiled-coil containing 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BCL6B B-cell CLL/lymphoma 6, member B
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTBD7 BTB (POZ) domain containing 7
C10ORF120 chromosome 10 open reading frame 120
C11ORF95 chromosome 11 open reading frame 95
C14ORF177 chromosome 14 open reading frame 177
C15ORF26 chromosome 15 open reading frame 26
C3ORF36 chromosome 3 open reading frame 36
C3ORF70 chromosome 3 open reading frame 70
C5AR2 complement component 5a receptor 2
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALCRL calcitonin receptor-like
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASC3 cancer susceptibility candidate 3
CASQ2 calsequestrin 2 (cardiac muscle)
CCDC129 coiled-coil domain containing 129
CCDC149 coiled-coil domain containing 149
CD93 CD93 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH13 cadherin 13
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEP68 centrosomal protein 68kDa
CERK ceramide kinase
CHRM3 cholinergic receptor, muscarinic 3
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CPM carboxypeptidase M
CPNE5 copine V
CRACR2A calcium release activated channel regulator 2A
CRTC3 CREB regulated transcription coactivator 3
CSN2 casein beta
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXXC4 CXXC finger protein 4
CYSLTR1 cysteinyl leukotriene receptor 1
CYTH3 cytohesin 3
CYYR1 cysteine/tyrosine-rich 1
DAB2IP DAB2 interacting protein
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DEFB135 defensin, beta 135
DEFB136 defensin, beta 136
DENND2C DENN/MADD domain containing 2C
DENND3 DENN/MADD domain containing 3
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DGKH diacylglycerol kinase, eta
DIXDC1 DIX domain containing 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DLL1 delta-like 1 (Drosophila)
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18
DOCK9 dedicator of cytokinesis 9
DUSP7 dual specificity phosphatase 7
EBF3 early B-cell factor 3
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EHD4 EH-domain containing 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
EPC2 enhancer of polycomb homolog 2 (Drosophila)
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHB4 EPH receptor B4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM124B family with sequence similarity 124B
FAM13B family with sequence similarity 13, member B
FAM160B1 family with sequence similarity 160, member B1
FAM21A family with sequence similarity 21, member A
FAM43B family with sequence similarity 43, member B
FAM53B family with sequence similarity 53, member B
FAM84A family with sequence similarity 84, member A
FAM9C family with sequence similarity 9, member C
FHL5 four and a half LIM domains 5
FILIP1 filamin A interacting protein 1
FILIP1L filamin A interacting protein 1-like
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FMNL3 formin-like 3
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FRMD8 FERM domain containing 8
FZD4 frizzled class receptor 4
GAB4 GRB2-associated binding protein family, member 4
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GAN gigaxonin
GATSL2 GATS protein-like 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GFRAL GDNF family receptor alpha like
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GIMAP7 GTPase, IMAP family member 7
GIMAP8 GTPase, IMAP family member 8
GJC1 gap junction protein, gamma 1, 45kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPR161 G protein-coupled receptor 161
GPR176 G protein-coupled receptor 176
GPR3 G protein-coupled receptor 3
GRB10 growth factor receptor-bound protein 10
GSN gelsolin
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HDAC4 histone deacetylase 4
HECA headcase homolog (Drosophila)
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HMBOX1 homeobox containing 1
HSPG2 heparan sulfate proteoglycan 2
HYAL2 hyaluronoglucosaminidase 2
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGF1R insulin-like growth factor 1 receptor
IGFL1 IGF-like family member 1
IL6ST interleukin 6 signal transducer
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INSR insulin receptor
IPO11 importin 11
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA10 integrin, alpha 10
ITGA9 integrin, alpha 9
KALRN kalirin, RhoGEF kinase
KAT6A K(lysine) acetyltransferase 6A
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIAA0355 KIAA0355
KIAA1211L KIAA1211-like
KIAA1462 KIAA1462
KIAA1671 KIAA1671
KIF17 kinesin family member 17
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIRREL kin of IRRE like (Drosophila)
KLF13 Kruppel-like factor 13
KLF7 Kruppel-like factor 7 (ubiquitous)
KLF9 Kruppel-like factor 9
KLHL11 kelch-like family member 11
KLHL23 kelch-like family member 23
KLHL38 kelch-like family member 38
KLHL5 kelch-like family member 5
LATS2 large tumor suppressor kinase 2
LAYN layilin
LDB2 LIM domain binding 2
LIMD1 LIM domains containing 1
LINC00341 long intergenic non-protein coding RNA 341
LOC221122 uncharacterized LOC221122
LPP LIM domain containing preferred translocation partner in lipoma
LRRC70 leucine rich repeat containing 70
LRRC8A leucine rich repeat containing 8 family, member A
LUZP1 leucine zipper protein 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAML3 mastermind-like 3 (Drosophila)
MAP1B microtubule-associated protein 1B
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MCC mutated in colorectal cancers
MCF2L MCF.2 cell line derived transforming sequence-like
MCTP1 multiple C2 domains, transmembrane 1
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
MKL2 MKL/myocardin-like 2
MOV10L1 Mov10 RISC complex RNA helicase like 1
MTCH1 mitochondrial carrier 1
MTUS1 microtubule associated tumor suppressor 1
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MXD4 MAX dimerization protein 4
MYOM1 myomesin 1
NCOA3 nuclear receptor coactivator 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NHSL2 NHS-like 2
NOL4L nucleolar protein 4-like
NOTCH4 notch 4
NRP1 neuropilin 1
OLFML2A olfactomedin-like 2A
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OR51S1 olfactory receptor, family 51, subfamily S, member 1
OR5A2 olfactory receptor, family 5, subfamily A, member 2
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OSBPL11 oxysterol binding protein-like 11
OSTN osteocrin
OTUD7A OTU deubiquitinase 7A
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PABPC4L poly(A) binding protein, cytoplasmic 4-like
PASK PAS domain containing serine/threonine kinase
PCDH12 protocadherin 12
PCDHB16 protocadherin beta 16
PCDHB4 protocadherin beta 4
PCDHGA6 protocadherin gamma subfamily A, 6
PDCL phosducin-like
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE5A phosphodiesterase 5A, cGMP-specific
PDE8A phosphodiesterase 8A
PDE8B phosphodiesterase 8B
PDGFD platelet derived growth factor D
PEAK1 pseudopodium-enriched atypical kinase 1
PGAP1 post-GPI attachment to proteins 1
PHACTR2 phosphatase and actin regulator 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PINK1 PTEN induced putative kinase 1
PKD1L1 polycystic kidney disease 1 like 1
PKP1 plakophilin 1
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLVAP plasmalemma vesicle associated protein
POMK protein-O-mannose kinase
POU6F2 POU class 6 homeobox 2
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PPARD peroxisome proliferator-activated receptor delta
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRDM11 PR domain containing 11
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCH protein kinase C, eta
PRKG1 protein kinase, cGMP-dependent, type I
PRR29 proline rich 29
PRRC2B proline-rich coiled-coil 2B
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRR protein tyrosine phosphatase, receptor type, R
PTX4 pentraxin 4, long
RAP2A RAP2A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RBMS3 RNA binding motif, single stranded interacting protein 3
RC3H1 ring finger and CCCH-type domains 1
RC3H2 ring finger and CCCH-type domains 2
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFTN1 raftlin, lipid raft linker 1
RFTN2 raftlin family member 2
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOJ ras homolog family member J
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASE11 ribonuclease, RNase A family, 11 (non-active)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORA RAR-related orphan receptor A
RPGR retinitis pigmentosa GTPase regulator
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S1PR1 sphingosine-1-phosphate receptor 1
SAP30L SAP30-like
SASH1 SAM and SH3 domain containing 1
SCARF1 scavenger receptor class F, member 1
SCARNA15 small Cajal body-specific RNA 15
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEC14L1 SEC14-like 1 (S. cerevisiae)
SH2D3C SH2 domain containing 3C
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHE Src homology 2 domain containing E
SHROOM4 shroom family member 4
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC35F1 solute carrier family 35, member F1
SLC38A11 solute carrier family 38, member 11
SLC38A2 solute carrier family 38, member 2
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNED1 sushi, nidogen and EGF-like domains 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORCS2 sortilin-related VPS10 domain containing receptor 2
SOX13 SRY (sex determining region Y)-box 13
SP6 Sp6 transcription factor
SPEM1 spermatid maturation 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPTBN1 spectrin, beta, non-erythrocytic 1
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STEAP4 STEAP family member 4
STIM2 stromal interaction molecule 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TACC1 transforming, acidic coiled-coil containing protein 1
TAL1 T-cell acute lymphocytic leukemia 1
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TBC1D10A TBC1 domain family, member 10A
TCF4 transcription factor 4
TEK TEK tyrosine kinase, endothelial
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TMEM2 transmembrane protein 2
TMEM204 transmembrane protein 204
TMOD2 tropomodulin 2 (neuronal)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM35 tripartite motif containing 35
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSPAN14 tetraspanin 14
TTLL11 tubulin tyrosine ligase-like family member 11
TTYH2 tweety family member 2
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UMODL1-AS1 UMODL1 antisense RNA 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
UTRN utrophin
VASH1 vasohibin 1
VEZF1 vascular endothelial zinc finger 1
VGLL4 vestigial-like family member 4
WASF2 WAS protein family, member 2
ZBTB16 zinc finger and BTB domain containing 16
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12C zinc finger CCCH-type containing 12C
ZDHHC20 zinc finger, DHHC-type containing 20
ZEB1 zinc finger E-box binding homeobox 1
ZFY zinc finger protein, Y-linked
ZNF189 zinc finger protein 189
ZNF235 zinc finger protein 235
ZNF283 zinc finger protein 283
ZNF304 zinc finger protein 304
ZNF366 zinc finger protein 366
ZNF423 zinc finger protein 423
ZNF516 zinc finger protein 516
ZNF518B zinc finger protein 518B
ZNF521 zinc finger protein 521
ZNF543 zinc finger protein 543
ZNF551 zinc finger protein 551
ZNF583 zinc finger protein 583
ZNF623 zinc finger protein 623
ZNF641 zinc finger protein 641
ZNF660 zinc finger protein 660
ZNF699 zinc finger protein 699
ZNF79 zinc finger protein 79
ZNF792 zinc finger protein 792
ZRANB1 zinc finger, RAN-binding domain containing 1
ZSCAN20 zinc finger and SCAN domain containing 20

low expression

Symbol Name
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)