Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4959-01A-01R-1334-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

396 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4959-01A-01R-1334-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACO2 aconitase 2, mitochondrial
ACOT7 acyl-CoA thioesterase 7
ACTL8 actin-like 8
ADORA3 adenosine A3 receptor
AFG3L2 AFG3-like AAA ATPase 2
AHCYL2 adenosylhomocysteinase-like 2
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPI alkaline phosphatase, intestinal
AMIGO1 adhesion molecule with Ig-like domain 1
ANGPTL3 angiopoietin-like 3
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANPEP alanyl (membrane) aminopeptidase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ASB13 ankyrin repeat and SOCS box containing 13
ASRGL1 asparaginase like 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BIN1 bridging integrator 1
BMP2K BMP2 inducible kinase
BNC2 basonuclin 2
BRI3BP BRI3 binding protein
C10ORF62 chromosome 10 open reading frame 62
C11ORF54 chromosome 11 open reading frame 54
C1QL3 complement component 1, q subcomponent-like 3
C3AR1 complement component 3a receptor 1
C4ORF19 chromosome 4 open reading frame 19
C9ORF129 chromosome 9 open reading frame 129
CACHD1 cache domain containing 1
CAPN1 calpain 1, (mu/I) large subunit
CCDC146 coiled-coil domain containing 146
CCL15 chemokine (C-C motif) ligand 15
CCL22 chemokine (C-C motif) ligand 22
CCR6 chemokine (C-C motif) receptor 6
CD300LB CD300 molecule-like family member b
CD84 CD84 molecule
CD99L2 CD99 molecule-like 2
CDHR1 cadherin-related family member 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDYL2 chromodomain protein, Y-like 2
CECR6 cat eye syndrome chromosome region, candidate 6
CEPT1 choline/ethanolamine phosphotransferase 1
CES2 carboxylesterase 2
CISD1 CDGSH iron sulfur domain 1
CIT citron rho-interacting serine/threonine kinase
CLEC18A C-type lectin domain family 18, member A
CLEC5A C-type lectin domain family 5, member A
CLPTM1L CLPTM1-like
CLRN1-AS1 CLRN1 antisense RNA 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTF ciliary neurotrophic factor
CORO2A coronin, actin binding protein, 2A
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPT2 carnitine palmitoyltransferase 2
CRAT carnitine O-acetyltransferase
CREG1 cellular repressor of E1A-stimulated genes 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRYBB1 crystallin, beta B1
CS citrate synthase
CTSE cathepsin E
CTSZ cathepsin Z
CXCL16 chemokine (C-X-C motif) ligand 16
CXORF40B chromosome X open reading frame 40B
CYB561D1 cytochrome b561 family, member D1
CYSLTR2 cysteinyl leukotriene receptor 2
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND1A DENN/MADD domain containing 1A
DENND1B DENN/MADD domain containing 1B
DERA deoxyribose-phosphate aldolase (putative)
DHFR dihydrofolate reductase
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNASE1L1 deoxyribonuclease I-like 1
DPH2 DPH2 homolog (S. cerevisiae)
DPP3 dipeptidyl-peptidase 3
DRAM2 DNA-damage regulated autophagy modulator 2
DTX4 deltex 4, E3 ubiquitin ligase
DUSP10 dual specificity phosphatase 10
DUSP3 dual specificity phosphatase 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DYSF dysferlin
EDN2 endothelin 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELMO3 engulfment and cell motility 3
EPB41 erythrocyte membrane protein band 4.1
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FAM120A family with sequence similarity 120A
FAM163B family with sequence similarity 163, member B
FAM210A family with sequence similarity 210, member A
FAM58BP cyclin-related protein FAM58B
FAM83F family with sequence similarity 83, member F
FAM99B family with sequence similarity 99, member B (non-protein coding)
FANCD2OS FANCD2 opposite strand
FBXO28 F-box protein 28
FBXW11 F-box and WD repeat domain containing 11
FGGY FGGY carbohydrate kinase domain containing
FICD FIC domain containing
FOXJ3 forkhead box J3
FUCA1 fucosidase, alpha-L- 1, tissue
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAGE12D G antigen 12D
GAGE12F G antigen 12F
GAGE2D G antigen 2D
GAGE4 G antigen 4
GAREM GRB2 associated, regulator of MAPK1
GC group-specific component (vitamin D binding protein)
GDA guanine deaminase
GDPGP1 GDP-D-glucose phosphorylase 1
GFRA1 GDNF family receptor alpha 1
GMPPB GDP-mannose pyrophosphorylase B
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPI glucose-6-phosphate isomerase
GPR101 G protein-coupled receptor 101
GPR107 G protein-coupled receptor 107
GPR34 G protein-coupled receptor 34
GPR35 G protein-coupled receptor 35
GPR89A G protein-coupled receptor 89A
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSTM4 glutathione S-transferase mu 4
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HAPLN4 hyaluronan and proteoglycan link protein 4
HAUS7 HAUS augmin-like complex, subunit 7
HAVCR1 hepatitis A virus cellular receptor 1
HEXA-AS1 HEXA antisense RNA 1
HHLA2 HERV-H LTR-associating 2
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HRH2 histamine receptor H2
HS1BP3 HCLS1 binding protein 3
HSDL2 hydroxysteroid dehydrogenase like 2
IDE insulin-degrading enzyme
IDS iduronate 2-sulfatase
IFFO2 intermediate filament family orphan 2
IL12RB2 interleukin 12 receptor, beta 2
IL13RA1 interleukin 13 receptor, alpha 1
IL22RA1 interleukin 22 receptor, alpha 1
IL7R interleukin 7 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IPMK inositol polyphosphate multikinase
IRAK1 interleukin-1 receptor-associated kinase 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KIAA0100 KIAA0100
KRTAP25-1 keratin associated protein 25-1
KRTAP5-6 keratin associated protein 5-6
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS4 lectin, galactoside-binding, soluble, 4
LIN54 lin-54 DREAM MuvB core complex component
LINC01548 long intergenic non-protein coding RNA 1548
LOC285627 uncharacterized LOC285627
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRP4 low density lipoprotein receptor-related protein 4
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC19 leucine rich repeat containing 19
LRRC7 leucine rich repeat containing 7
LRRC8B leucine rich repeat containing 8 family, member B
LRRC8D leucine rich repeat containing 8 family, member D
LTF lactotransferrin
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MARVELD3 MARVEL domain containing 3
MDH1 malate dehydrogenase 1, NAD (soluble)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MESDC2 mesoderm development candidate 2
MFN2 mitofusin 2
MFSD1 major facilitator superfamily domain containing 1
MIEF1 mitochondrial elongation factor 1
MISP mitotic spindle positioning
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MMGT1 membrane magnesium transporter 1
MPEG1 macrophage expressed 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPV17L MPV17 mitochondrial membrane protein-like
MS4A10 membrane-spanning 4-domains, subfamily A, member 10
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MTM1 myotubularin 1
MTMR1 myotubularin related protein 1
MYEOV myeloma overexpressed
MYH14 myosin, heavy chain 14, non-muscle
MYO5B myosin VB
MYOM3 myomesin 3
NAGA N-acetylgalactosaminidase, alpha-
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCEH1 neutral cholesterol ester hydrolase 1
NCOA4 nuclear receptor coactivator 4
NDFIP2 Nedd4 family interacting protein 2
NEK6 NIMA-related kinase 6
NIPAL2 NIPA-like domain containing 2
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLRP6 NLR family, pyrin domain containing 6
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSUN4 NOP2/Sun domain family, member 4
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NT5DC3 5'-nucleotidase domain containing 3
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR4C16 olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene)
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR6X1 olfactory receptor, family 6, subfamily X, member 1
OTOA otoancorin
PAAF1 proteasomal ATPase-associated factor 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PARVB parvin, beta
PCTP phosphatidylcholine transfer protein
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PDZD8 PDZ domain containing 8
PDZK1IP1 PDZK1 interacting protein 1
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PIAS2 protein inhibitor of activated STAT, 2
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PITPNA phosphatidylinositol transfer protein, alpha
PKLR pyruvate kinase, liver and RBC
PLA2G12A phospholipase A2, group XIIA
PLA2G12B phospholipase A2, group XIIB
PLCB4 phospholipase C, beta 4
PLS1 plastin 1
PLXDC2 plexin domain containing 2
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PNPO pyridoxamine 5'-phosphate oxidase
POLG polymerase (DNA directed), gamma
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPCS phosphopantothenoylcysteine synthetase
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRM2 protamine 2
PSAP prosaposin
PTAFR platelet-activating factor receptor
PTDSS1 phosphatidylserine synthase 1
PTER phosphotriesterase related
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK6 protein tyrosine kinase 6
PVRL3 poliovirus receptor-related 3
RAB19 RAB19, member RAS oncogene family
RAB22A RAB22A, member RAS oncogene family
RENBP renin binding protein
REPS2 RALBP1 associated Eps domain containing 2
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RIOK3 RIO kinase 3
RNF133 ring finger protein 133
RNF148 ring finger protein 148
RNF185 ring finger protein 185
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RSC1A1 regulatory solute carrier protein, family 1, member 1
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SAMM50 SAMM50 sorting and assembly machinery component
SARM1 sterile alpha and TIR motif containing 1
SCAMP5 secretory carrier membrane protein 5
SEC23B Sec23 homolog B (S. cerevisiae)
SEC31A SEC31 homolog A (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFT2D2 SFT2 domain containing 2
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SH2D5 SH2 domain containing 5
SH3GL2 SH3-domain GRB2-like 2
SHCBP1L SHC SH2-domain binding protein 1-like
SHISA9 shisa family member 9
SIAE sialic acid acetylesterase
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPA signal-regulatory protein alpha
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A3 solute carrier family 23, member 3
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A51 solute carrier family 25, member 51
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC38A1 solute carrier family 38, member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLURP1 secreted LY6/PLAUR domain containing 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMIM10L2A small integral membrane protein 10 like 2A
SNAP91 synaptosomal-associated protein, 91kDa
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA84 small nucleolar RNA, H/ACA box 84
SNX30 sorting nexin family member 30
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPESP1 sperm equatorial segment protein 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT5A signal transducer and activator of transcription 5A
STON1 stonin 1
SYN2 synapsin II
SYPL2 synaptophysin-like 2
TAS2R8 taste receptor, type 2, member 8
TEX11 testis expressed 11
TGFBR1 transforming growth factor, beta receptor 1
THAP9 THAP domain containing 9
TLR3 toll-like receptor 3
TM6SF2 transmembrane 6 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMED4 transmembrane emp24 protein transport domain containing 4
TMEM132E transmembrane protein 132E
TMEM187 transmembrane protein 187
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOR1AIP2 torsin A interacting protein 2
TREML4 triggering receptor expressed on myeloid cells-like 4
TREX2 three prime repair exonuclease 2
TRIM14 tripartite motif containing 14
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPAN1 tetraspanin 1
TSPAN3 tetraspanin 3
TTC22 tetratricopeptide repeat domain 22
TXNRD3NB thioredoxin reductase 3 neighbor
TYMS thymidylate synthetase
TYMSOS TYMS opposite strand
UBL4A ubiquitin-like 4A
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VBP1 von Hippel-Lindau binding protein 1
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
ZDHHC5 zinc finger, DHHC-type containing 5
ZFAT zinc finger and AT hook domain containing
ZMAT3 zinc finger, matrin-type 3

low expression

Symbol Name
AP3M2 adaptor-related protein complex 3, mu 2 subunit
BRD2 bromodomain containing 2
C2ORF44 chromosome 2 open reading frame 44
EXO5 exonuclease 5
HCG18 HLA complex group 18 (non-protein coding)
MDC1 mediator of DNA-damage checkpoint 1
NOL7 nucleolar protein 7, 27kDa
PHF10 PHD finger protein 10
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
RIC8B RIC8 guanine nucleotide exchange factor B
RSRC2 arginine/serine-rich coiled-coil 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TBP TATA box binding protein
TIGD7 tigger transposable element derived 7
ZNF222 zinc finger protein 222
ZNF329 zinc finger protein 329
ZNF440 zinc finger protein 440
ZNF569 zinc finger protein 569
ZNF570 zinc finger protein 570
ZNF599 zinc finger protein 599
ZNF790 zinc finger protein 790
ZSCAN12 zinc finger and SCAN domain containing 12