Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

364 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACACA acetyl-CoA carboxylase alpha
ACAN aggrecan
ACLY ATP citrate lyase
ACVR1 activin A receptor, type I
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADCK2 aarF domain containing kinase 2
ADD2 adducin 2 (beta)
ADGRG1 adhesion G protein-coupled receptor G1
AGGF1 angiogenic factor with G patch and FHA domains 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGXT2 alanine--glyoxylate aminotransferase 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
ANAPC1 anaphase promoting complex subunit 1
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD7 ankyrin repeat domain 7
ANOS1 anosmin 1
ANTXR1 anthrax toxin receptor 1
ANXA4 annexin A4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP1 Rho GTPase activating protein 1
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARSB arylsulfatase B
ATG10 autophagy related 10
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
AVL9 AVL9 homolog (S. cerevisiase)
BCL7B B-cell CLL/lymphoma 7B
BHMT betaine--homocysteine S-methyltransferase
BHMT2 betaine--homocysteine S-methyltransferase 2
C5ORF22 chromosome 5 open reading frame 22
C6ORF120 chromosome 6 open reading frame 120
C7ORF49 chromosome 7 open reading frame 49
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CBWD2 COBW domain containing 2
CCDC132 coiled-coil domain containing 132
CCDC80 coiled-coil domain containing 80
CCIN calicin
CCM2 cerebral cavernous malformation 2
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDC23 cell division cycle 23
CDK5 cyclin-dependent kinase 5
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDYL2 chromodomain protein, Y-like 2
CENPO centromere protein O
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHRND cholinergic receptor, nicotinic, delta (muscle)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCN3 chloride channel, voltage-sensitive 3
CNTNAP5 contactin associated protein-like 5
COL16A1 collagen, type XVI, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL1A2 collagen, type I, alpha 2
COL23A1 collagen, type XXIII, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
COPS8 COP9 signalosome subunit 8
CRLF1 cytokine receptor-like factor 1
CRMP1 collapsin response mediator protein 1
CUX1 cut-like homeobox 1
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CYB5R2 cytochrome b5 reductase 2
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBN1 drebrin 1
DBX1 developing brain homeobox 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DHFR dihydrofolate reductase
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DIAPH1 diaphanous-related formin 1
DISP2 dispatched homolog 2 (Drosophila)
DLD dihydrolipoamide dehydrogenase
DMBT1 deleted in malignant brain tumors 1
DMGDH dimethylglycine dehydrogenase
DNAAF5 dynein, axonemal, assembly factor 5
DYDC1 DPY30 domain containing 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4H eukaryotic translation initiation factor 4H
ELAC2 elaC ribonuclease Z 2
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELN elastin
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHB1 EPH receptor B1
ERCC8 excision repair cross-complementation group 8
ETF1 eukaryotic translation termination factor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP6 fatty acid binding protein 6, ileal
FAF2 Fas associated factor family member 2
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAM129A family with sequence similarity 129, member A
FAM20C family with sequence similarity 20, member C
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM98A family with sequence similarity 98, member A
FAP fibroblast activation protein, alpha
FARSB phenylalanyl-tRNA synthetase, beta subunit
FASTKD1 FAST kinase domains 1
FASTKD2 FAST kinase domains 2
FBLN2 fibulin 2
FBN1 fibrillin 1
FBXL18 F-box and leucine-rich repeat protein 18
FBXO41 F-box protein 41
FBXW11 F-box and WD repeat domain containing 11
FNDC1 fibronectin type III domain containing 1
FNDC8 fibronectin type III domain containing 8
FRZB frizzled-related protein
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
GCFC2 GC-rich sequence DNA-binding factor 2
GDF10 growth differentiation factor 10
GLP1R glucagon-like peptide 1 receptor
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPR142 G protein-coupled receptor 142
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRAPL GRB2-related adaptor protein-like
GRPR gastrin-releasing peptide receptor
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTPBP10 GTP-binding protein 10 (putative)
H2AFV H2A histone family, member V
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HDAC3 histone deacetylase 3
HDLBP high density lipoprotein binding protein
HOXA13 homeobox A13
HOXC12 homeobox C12
HSPA9 heat shock 70kDa protein 9 (mortalin)
IFT22 intraflagellar transport 22
IGSF9 immunoglobulin superfamily, member 9
IMMT inner membrane protein, mitochondrial
INTS1 integrator complex subunit 1
IQCE IQ motif containing E
ITGA11 integrin, alpha 11
ITGAV integrin, alpha V
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KIAA0754 KIAA0754
KIF2A kinesin heavy chain member 2A
KLHDC8A kelch domain containing 8A
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LARP1 La ribonucleoprotein domain family, member 1
LARS leucyl-tRNA synthetase
LBH limb bud and heart development
LCE3E late cornified envelope 3E
LHCGR luteinizing hormone/choriogonadotropin receptor
LOC285768 uncharacterized LOC285768
LOC441204 uncharacterized LOC441204
LOC90784 uncharacterized LOC90784
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC3 leucine rich repeat containing 3
LRRC4 leucine rich repeat containing 4
LRRN2 leucine rich repeat neuronal 2
LTBP2 latent transforming growth factor beta binding protein 2
LYZL4 lysozyme-like 4
MACF1 microtubule-actin crosslinking factor 1
MAP7D2 MAP7 domain containing 2
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MATK megakaryocyte-associated tyrosine kinase
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCM6 minichromosome maintenance complex component 6
MCTS2P malignant T cell amplified sequence 2, pseudogene
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
METTL2B methyltransferase like 2B
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MNX1 motor neuron and pancreas homeobox 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPPED1 metallophosphoesterase domain containing 1
MRGPRE MAS-related GPR, member E
MRPL30 mitochondrial ribosomal protein L30
MRPS27 mitochondrial ribosomal protein S27
MSH3 mutS homolog 3
MSX2 msh homeobox 2
MTIF2 mitochondrial translational initiation factor 2
MTX3 metaxin 3
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYO1D myosin ID
NACAD NAC alpha domain containing
NCK2 NCK adaptor protein 2
NEK6 NIMA-related kinase 6
NEO1 neogenin 1
NIFK nucleolar protein interacting with the FHA domain of MKI67
NOL6 nucleolar protein 6 (RNA-associated)
NRCAM neuronal cell adhesion molecule
NUP155 nucleoporin 155kDa
NUP205 nucleoporin 205kDa
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2T33 olfactory receptor, family 2, subfamily T, member 33
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHB10 protocadherin beta 10
PCDHB12 protocadherin beta 12
PCDHB13 protocadherin beta 13
PCDHB14 protocadherin beta 14
PCDHB16 protocadherin beta 16
PCDHB17P protocadherin beta 17 pseudogene
PCDHB5 protocadherin beta 5
PCDHB6 protocadherin beta 6
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCDHB9 protocadherin beta 9
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGC4 protocadherin gamma subfamily C, 4
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM5 PDZ and LIM domain 5
PGLYRP4 peptidoglycan recognition protein 4
PITX1 paired-like homeodomain 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121C POM121 transmembrane nucleoporin C
POMZP3 POM121 and ZP3 fusion
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR34 proline rich 34
PRSS21 protease, serine, 21 (testisin)
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTCD2 pentatricopeptide repeat domain 2
PUS7 pseudouridylate synthase 7 (putative)
PXDN peroxidasin
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAD17 RAD17 homolog (S. pombe)
RBPMS2 RNA binding protein with multiple splicing 2
RHBDD1 rhomboid domain containing 1
RNASEH1 ribonuclease H1
RNF145 ring finger protein 145
RNF216 ring finger protein 216
RSBN1L round spermatid basic protein 1-like
RXFP3 relaxin/insulin-like family peptide receptor 3
RYR2 ryanodine receptor 2 (cardiac)
SCARF2 scavenger receptor class F, member 2
SCLY selenocysteine lyase
SCN3B sodium channel, voltage gated, type III beta subunit
SEC31A SEC31 homolog A (S. cerevisiae)
SFT2D3 SFT2 domain containing 3
SFXN5 sideroflexin 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC17A2 solute carrier family 17, member 2
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A46 solute carrier family 25, member 46
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35A4 solute carrier family 35, member A4
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35F6 solute carrier family 35, member F6
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMO smoothened, frizzled class receptor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNX29 sorting nexin 29
SORBS2 sorbin and SH3 domain containing 2
SPRR2G small proline-rich protein 2G
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRBD1 S1 RNA binding domain 1
SSTR4 somatostatin receptor 4
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAMBP STAM binding protein
STRADB STE20-related kinase adaptor beta
STRIP2 striatin interacting protein 2
SULF1 sulfatase 1
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
TARS threonyl-tRNA synthetase
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCF12 transcription factor 12
TEX26 testis expressed 26
TEX261 testis expressed 261
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THADA thyroid adenoma associated
THBS2 thrombospondin 2
TMEM132B transmembrane protein 132B
TMEM182 transmembrane protein 182
TMEM185B transmembrane protein 185B
TMEM209 transmembrane protein 209
TMEM248 transmembrane protein 248
TMEM63B transmembrane protein 63B
TNPO3 transportin 3
TPST1 tyrosylprotein sulfotransferase 1
TRIM23 tripartite motif containing 23
TRIP12 thyroid hormone receptor interactor 12
TRRAP transformation/transcription domain-associated protein
TSN translin
TSPAN17 tetraspanin 17
TSPAN33 tetraspanin 33
TTC27 tetratricopeptide repeat domain 27
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TTC37 tetratricopeptide repeat domain 37
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE3C ubiquitin protein ligase E3C
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UGDH UDP-glucose 6-dehydrogenase
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UNC13B unc-13 homolog B (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP50 ubiquitin specific peptidase 50
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
WASL Wiskott-Aldrich syndrome-like
WBSCR16 Williams-Beuren syndrome chromosome region 16
WBSCR22 Williams Beuren syndrome chromosome region 22
WDR36 WD repeat domain 36
WDR41 WD repeat domain 41
WIPF3 WAS/WASL interacting protein family, member 3
XPO5 exportin 5
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBED3 zinc finger, BED-type containing 3
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZIC1 Zic family member 1
ZNF138 zinc finger protein 138
ZPBP zona pellucida binding protein

low expression

Symbol Name
BSDC1 BSD domain containing 1
C18ORF25 chromosome 18 open reading frame 25
C1ORF174 chromosome 1 open reading frame 174
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
KIN Kin17 DNA and RNA binding protein
MEAF6 MYST/Esa1-associated factor 6
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MTAP methylthioadenosine phosphorylase
PRPF18 pre-mRNA processing factor 18
RBM4B RNA binding motif protein 4B
RSRC2 arginine/serine-rich coiled-coil 2
SF3A3 splicing factor 3a, subunit 3, 60kDa
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
ZNF33A zinc finger protein 33A