Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

342 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A1CF APOBEC1 complementation factor
AASS aminoadipate-semialdehyde synthase
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABHD15 abhydrolase domain containing 15
ACAD11 acyl-CoA dehydrogenase family, member 11
ACE2 angiotensin I converting enzyme 2
ADCY9 adenylate cyclase 9
ADNP2 ADNP homeobox 2
AEN apoptosis enhancing nuclease
AFTPH aftiphilin
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AGPS alkylglycerone phosphate synthase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AQP7 aquaporin 7
ARHGAP32 Rho GTPase activating protein 32
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL5B ADP-ribosylation factor-like 5B
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ATP11A ATPase, class VI, type 11A
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN1L ataxin 1-like
AVPR1B arginine vasopressin receptor 1B
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCL2 B-cell CLL/lymphoma 2
BCOR BCL6 corepressor
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD7 BTB (POZ) domain containing 7
C12ORF49 chromosome 12 open reading frame 49
C16ORF72 chromosome 16 open reading frame 72
C17ORF105 chromosome 17 open reading frame 105
C1ORF95 chromosome 1 open reading frame 95
C2ORF54 chromosome 2 open reading frame 54
C4ORF19 chromosome 4 open reading frame 19
C5ORF51 chromosome 5 open reading frame 51
C6 complement component 6
CABLES1 Cdk5 and Abl enzyme substrate 1
CABP1 calcium binding protein 1
CCL24 chemokine (C-C motif) ligand 24
CCND1 cyclin D1
CCNYL1 cyclin Y-like 1
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC37L1 cell division cycle 37-like 1
CDHR2 cadherin-related family member 2
CDHR5 cadherin-related family member 5
CDYL2 chromodomain protein, Y-like 2
CEP170P1 centrosomal protein 170kDa pseudogene 1
CFAP126 cilia and flagella associated protein 126
CHAD chondroadherin
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CIART circadian associated repressor of transcription
CLCN5 chloride channel, voltage-sensitive 5
CLOCK clock circadian regulator
CLVS2 clavesin 2
CNKSR3 CNKSR family member 3
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CORO1C coronin, actin binding protein, 1C
CSDC2 cold shock domain containing C2, RNA binding
CST1 cystatin SN
CTNND1 catenin (cadherin-associated protein), delta 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCTN5 dynactin 5 (p25)
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND4C DENN/MADD domain containing 4C
DENND5B DENN/MADD domain containing 5B
DGKH diacylglycerol kinase, eta
DHFRL1 dihydrofolate reductase-like 1
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOLK dolichol kinase
DSC2 desmocollin 2
DSCR3 Down syndrome critical region 3
DSEL dermatan sulfate epimerase-like
DUSP16 dual specificity phosphatase 16
DYTN dystrotelin
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR4 early growth response 4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EML4 echinoderm microtubule associated protein like 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOC5 exocyst complex component 5
EXOC8 exocyst complex component 8
F5 coagulation factor V (proaccelerin, labile factor)
FAM110C family with sequence similarity 110, member C
FAM134B family with sequence similarity 134, member B
FAM135A family with sequence similarity 135, member A
FAM138D family with sequence similarity 138, member D
FAM138E family with sequence similarity 138, member E
FBXO3 F-box protein 3
FEM1B fem-1 homolog b (C. elegans)
FICD FIC domain containing
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FNIP2 folliculin interacting protein 2
FOXN3 forkhead box N3
FRMD6 FERM domain containing 6
FRMPD2 FERM and PDZ domain containing 2
FUCA2 fucosidase, alpha-L- 2, plasma
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GALC galactosylceramidase
GALK2 galactokinase 2
GAN gigaxonin
GAREM GRB2 associated, regulator of MAPK1
GK3P glycerol kinase 3 pseudogene
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GOLIM4 golgi integral membrane protein 4
GOSR1 golgi SNAP receptor complex member 1
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
HEXB hexosaminidase B (beta polypeptide)
HHLA2 HERV-H LTR-associating 2
HIPK2 homeodomain interacting protein kinase 2
HIST1H2AA histone cluster 1, H2aa
HIST1H2BA histone cluster 1, H2ba
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HRH2 histamine receptor H2
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGF2R insulin-like growth factor 2 receptor
IL17RD interleukin 17 receptor D
IL6R interleukin 6 receptor
INTS6 integrator complex subunit 6
INVS inversin
ITGA8 integrin, alpha 8
KDSR 3-ketodihydrosphingosine reductase
KIAA0100 KIAA0100
KIAA1958 KIAA1958
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
KLF9 Kruppel-like factor 9
KLHL9 kelch-like family member 9
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LCLAT1 lysocardiolipin acyltransferase 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3
LYZ lysozyme
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAML2 mastermind-like 2 (Drosophila)
MAP7 microtubule-associated protein 7
MAPK1 mitogen-activated protein kinase 1
MAPK6 mitogen-activated protein kinase 6
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARVELD3 MARVEL domain containing 3
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MED13 mediator complex subunit 13
MED13L mediator complex subunit 13-like
METTL14 methyltransferase like 14
METTL7B methyltransferase like 7B
MICU1 mitochondrial calcium uptake 1
MLEC malectin
MRPL50 mitochondrial ribosomal protein L50
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTMR12 myotubularin related protein 12
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NCOA4 nuclear receptor coactivator 4
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1
NET1 neuroepithelial cell transforming 1
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NHLRC3 NHL repeat containing 3
NLRP6 NLR family, pyrin domain containing 6
NOL4 nucleolar protein 4
NOP9 NOP9 nucleolar protein
NPR3 natriuretic peptide receptor 3
NRIP1 nuclear receptor interacting protein 1
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
NUP153 nucleoporin 153kDa
OR4D2 olfactory receptor, family 4, subfamily D, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR52N5 olfactory receptor, family 52, subfamily N, member 5
OSBPL8 oxysterol binding protein-like 8
PCDHB10 protocadherin beta 10
PCSK5 proprotein convertase subtilisin/kexin type 5
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PDZD8 PDZ domain containing 8
PDZK1P1 PDZ domain containing 1 pseudogene 1
PER2 period circadian clock 2
PGM3 phosphoglucomutase 3
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PKLR pyruvate kinase, liver and RBC
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRODH proline dehydrogenase (oxidase) 1
PRR26 proline rich 26
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PURA purine-rich element binding protein A
PVRL3 poliovirus receptor-related 3
RAB3IP RAB3A interacting protein
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF219 ring finger protein 219
SALL1 spalt-like transcription factor 1
SAMD5 sterile alpha motif domain containing 5
SATB2 SATB homeobox 2
SEC16A SEC16 homolog A (S. cerevisiae)
SEC23IP SEC23 interacting protein
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SESTD1 SEC14 and spectrin domains 1
SETD3 SET domain containing 3
SETD7 SET domain containing (lysine methyltransferase) 7
SETX senataxin
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC16A13 solute carrier family 16, member 13
SLC16A9 solute carrier family 16, member 9
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC23A3 solute carrier family 23, member 3
SLC25A44 solute carrier family 25, member 44
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC39A9 solute carrier family 39, member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNORA5B small nucleolar RNA, H/ACA box 5B
SNX29 sorting nexin 29
SNX9 sorting nexin 9
SOCS4 suppressor of cytokine signaling 4
SOCS6 suppressor of cytokine signaling 6
SOCS7 suppressor of cytokine signaling 7
SOWAHC sosondowah ankyrin repeat domain family member C
SPATA31E1 SPATA31 subfamily E, member 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRPR signal recognition particle receptor (docking protein)
STK32B serine/threonine kinase 32B
STRN3 striatin, calmodulin binding protein 3
SUSD6 sushi domain containing 6
SYT9 synaptotagmin IX
TBC1D22B TBC1 domain family, member 22B
TBL1X transducin (beta)-like 1X-linked
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEX2 testis expressed 2
TINAG tubulointerstitial nephritis antigen
TM7SF3 transmembrane 7 superfamily member 3
TM9SF1 transmembrane 9 superfamily member 1
TMEM144 transmembrane protein 144
TMEM185B transmembrane protein 185B
TMEM19 transmembrane protein 19
TMEM194B transmembrane protein 194B
TMEM200A transmembrane protein 200A
TMEM38B transmembrane protein 38B
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOB2 transducer of ERBB2, 2
TOLLIP toll interacting protein
TOR1AIP2 torsin A interacting protein 2
TPP1 tripeptidyl peptidase I
TPPP tubulin polymerization promoting protein
TPSD1 tryptase delta 1
TREH trehalase (brush-border membrane glycoprotein)
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM13 tripartite motif containing 13
TRIM26 tripartite motif containing 26
TRIM44 tripartite motif containing 44
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSC22D2 TSC22 domain family, member 2
TSPAN19 tetraspanin 19
TSPYL1 TSPY-like 1
TTC5 tetratricopeptide repeat domain 5
TTYH3 tweety family member 3
TUG1 taurine up-regulated 1 (non-protein coding)
UBN1 ubinuclein 1
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UPB1 ureidopropionase, beta
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP2 ubiquitin specific peptidase 2
USP38 ubiquitin specific peptidase 38
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
WDPCP WD repeat containing planar cell polarity effector
WDR7 WD repeat domain 7
WIPF2 WAS/WASL interacting protein family, member 2
WWTR1 WW domain containing transcription regulator 1
YIPF6 Yip1 domain family, member 6
ZBED4 zinc finger, BED-type containing 4
ZBTB10 zinc finger and BTB domain containing 10
ZBTB20 zinc finger and BTB domain containing 20
ZBTB21 zinc finger and BTB domain containing 21
ZCCHC2 zinc finger, CCHC domain containing 2
ZDHHC5 zinc finger, DHHC-type containing 5
ZDHHC9 zinc finger, DHHC-type containing 9
ZFAND5 zinc finger, AN1-type domain 5
ZNF189 zinc finger protein 189
ZNF367 zinc finger protein 367

low expression

Symbol Name
C1ORF109 chromosome 1 open reading frame 109
C1ORF52 chromosome 1 open reading frame 52
LRRC47 leucine rich repeat containing 47
NFYC nuclear transcription factor Y, gamma
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
SF3A3 splicing factor 3a, subunit 3, 60kDa
TMEM222 transmembrane protein 222
TMEM69 transmembrane protein 69
ZCCHC17 zinc finger, CCHC domain containing 17