Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

421 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABLIM2 actin binding LIM protein family, member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTL8 actin-like 8
AFF4 AF4/FMR2 family, member 4
AGGF1 angiogenic factor with G patch and FHA domains 1
AGXT2 alanine--glyoxylate aminotransferase 2
AHCYL1 adenosylhomocysteinase-like 1
AKR7L aldo-keto reductase family 7-like (gene/pseudogene)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX5 arachidonate 5-lipoxygenase
ALPI alkaline phosphatase, intestinal
AMIGO1 adhesion molecule with Ig-like domain 1
ANGPTL3 angiopoietin-like 3
ANKRD6 ankyrin repeat domain 6
ANPEP alanyl (membrane) aminopeptidase
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARRDC3 arrestin domain containing 3
ASPA aspartoacylase
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BARX2 BARX homeobox 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BHMT2 betaine--homocysteine S-methyltransferase 2
BIRC7 baculoviral IAP repeat containing 7
BMP8B bone morphogenetic protein 8b
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTBD10 BTB (POZ) domain containing 10
C10ORF76 chromosome 10 open reading frame 76
C11ORF58 chromosome 11 open reading frame 58
C11ORF65 chromosome 11 open reading frame 65
C1ORF74 chromosome 1 open reading frame 74
C5ORF22 chromosome 5 open reading frame 22
C6ORF106 chromosome 6 open reading frame 106
C6ORF201 chromosome 6 open reading frame 201
C9ORF129 chromosome 9 open reading frame 129
CANX calnexin
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPN14 calpain 14
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CAST calpastatin
CBWD3 COBW domain containing 3
CBWD5 COBW domain containing 5
CC2D2A coiled-coil and C2 domain containing 2A
CCDC125 coiled-coil domain containing 125
CCR6 chemokine (C-C motif) receptor 6
CD68 CD68 molecule
CDHR5 cadherin-related family member 5
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEPT1 choline/ethanolamine phosphotransferase 1
CHURC1 churchill domain containing 1
CIDEB cell death-inducing DFFA-like effector b
CISD1 CDGSH iron sulfur domain 1
CIT citron rho-interacting serine/threonine kinase
CLCN3 chloride channel, voltage-sensitive 3
CLPTM1L CLPTM1-like
CMIP c-Maf inducing protein
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPB1 coatomer protein complex, subunit beta 1
CORO2A coronin, actin binding protein, 2A
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPNE8 copine VIII
CPT2 carnitine palmitoyltransferase 2
CRIP3 cysteine-rich protein 3
CTAGE5 CTAGE family, member 5
CTNND1 catenin (cadherin-associated protein), delta 1
CTSD cathepsin D
CTSL cathepsin L
CTSL3P cathepsin L family member 3, pseudogene
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DENND4C DENN/MADD domain containing 4C
DERA deoxyribose-phosphate aldolase (putative)
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DKFZP434K028 uncharacterized LOC26070
DMGDH dimethylglycine dehydrogenase
DMXL1 Dmx-like 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DPP4 dipeptidyl-peptidase 4
DRAM1 DNA-damage regulated autophagy modulator 1
DRAM2 DNA-damage regulated autophagy modulator 2
EFTUD1 elongation factor Tu GTP binding domain containing 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41 erythrocyte membrane protein band 4.1
EPS8L3 EPS8-like 3
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC5 excision repair cross-complementation group 5
ERO1L ERO1-like (S. cerevisiae)
ERP44 endoplasmic reticulum protein 44
ESYT3 extended synaptotagmin-like protein 3
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM120A family with sequence similarity 120A
FAM120AOS family with sequence similarity 120A opposite strand
FAM160A2 family with sequence similarity 160, member A2
FAM206A family with sequence similarity 206, member A
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM81B family with sequence similarity 81, member B
FASTKD3 FAST kinase domains 3
FBXL5 F-box and leucine-rich repeat protein 5
FFAR3 free fatty acid receptor 3
FGD6 FYVE, RhoGEF and PH domain containing 6
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FNIP1 folliculin interacting protein 1
FRRS1 ferric-chelate reductase 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GALK2 galactokinase 2
GANC glucosidase, alpha; neutral C
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GAS2L3 growth arrest-specific 2 like 3
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GGT8P gamma-glutamyltransferase 8 pseudogene
GIPC2 GIPC PDZ domain containing family, member 2
GLCE glucuronic acid epimerase
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GPM6A glycoprotein M6A
GPR35 G protein-coupled receptor 35
GSR glutathione reductase
GTF2H2C GTF2H2 family member C
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HAPLN4 hyaluronan and proteoglycan link protein 4
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HAVCR1 hepatitis A virus cellular receptor 1
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BN histone cluster 1, H2bn
HK2 hexokinase 2
HLA-C major histocompatibility complex, class I, C
HLA-G major histocompatibility complex, class I, G
HLA-H major histocompatibility complex, class I, H (pseudogene)
HLF hepatic leukemia factor
HNF4G hepatocyte nuclear factor 4, gamma
HOOK2 hook microtubule-tethering protein 2
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IL10 interleukin 10
IL22RA1 interleukin 22 receptor, alpha 1
IMPG1 interphotoreceptor matrix proteoglycan 1
INADL InaD-like (Drosophila)
IPMK inositol polyphosphate multikinase
IPO7 importin 7
IRF8 interferon regulatory factor 8
ITGAD integrin, alpha D
ITGB8 integrin, beta 8
JAK1 Janus kinase 1
JKAMP JNK1/MAPK8-associated membrane protein
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KDM1B lysine (K)-specific demethylase 1B
KDM4C lysine (K)-specific demethylase 4C
KHK ketohexokinase (fructokinase)
KIAA0141 KIAA0141
KIAA1715 KIAA1715
KIAA1919 KIAA1919
KIAA1958 KIAA1958
KLHDC10 kelch domain containing 10
KLHDC7A kelch domain containing 7A
KSR1 kinase suppressor of ras 1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAD1 ladinin 1
LARP1 La ribonucleoprotein domain family, member 1
LARP1B La ribonucleoprotein domain family, member 1B
LCOR ligand dependent nuclear receptor corepressor
LEAP2 liver expressed antimicrobial peptide 2
LEPROTL1 leptin receptor overlapping transcript-like 1
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00113 long intergenic non-protein coding RNA 113
LINC00161 long intergenic non-protein coding RNA 161
LINC00202-1 long intergenic non-protein coding RNA 202-1
LIPA lipase A, lysosomal acid, cholesterol esterase
LMX1A LIM homeobox transcription factor 1, alpha
LOC100129034 uncharacterized LOC100129034
LOC100130872 uncharacterized LOC100130872
LOC115110 uncharacterized LOC115110
LOC286238 uncharacterized LOC286238
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP4 low density lipoprotein receptor-related protein 4
LRRC19 leucine rich repeat containing 19
LRRC7 leucine rich repeat containing 7
LY6G6D lymphocyte antigen 6 complex, locus G6D
MACC1 metastasis associated in colon cancer 1
MAML2 mastermind-like 2 (Drosophila)
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK9 mitogen-activated protein kinase 9
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MARVELD3 MARVEL domain containing 3
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MCTS2P malignant T cell amplified sequence 2, pseudogene
MEGF6 multiple EGF-like-domains 6
MEP1A meprin A, alpha (PABA peptide hydrolase)
MFSD9 major facilitator superfamily domain containing 9
MLH3 mutL homolog 3
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MOGAT3 monoacylglycerol O-acyltransferase 3
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL30 mitochondrial ribosomal protein L30
MS4A10 membrane-spanning 4-domains, subfamily A, member 10
MSH3 mutS homolog 3
MTMR2 myotubularin related protein 2
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTX3 metaxin 3
MYEOV myeloma overexpressed
MYOM3 myomesin 3
NCOA4 nuclear receptor coactivator 4
NEFL neurofilament, light polypeptide
NEK6 NIMA-related kinase 6
NFX1 nuclear transcription factor, X-box binding 1
NHEJ1 nonhomologous end-joining factor 1
NHLRC3 NHL repeat containing 3
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NKAIN4 Na+/K+ transporting ATPase interacting 4
NLGN1 neuroligin 1
NLRP6 NLR family, pyrin domain containing 6
NMT1 N-myristoyltransferase 1
NRN1 neuritin 1
NRSN1 neurensin 1
NUMB numb homolog (Drosophila)
OARD1 O-acyl-ADP-ribose deacylase 1
OCM2 oncomodulin 2
OPTN optineurin
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR9I1 olfactory receptor, family 9, subfamily I, member 1
OSMR oncostatin M receptor
OTULIN OTU deubiquitinase with linear linkage specificity
PAAF1 proteasomal ATPase-associated factor 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAM peptidylglycine alpha-amidating monooxygenase
PAPD4 PAP associated domain containing 4
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PGAP2 post-GPI attachment to proteins 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKDREJ polycystin (PKD) family receptor for egg jelly
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB4 phospholipase C, beta 4
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLIN2 perilipin 2
PLS1 plastin 1
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
POF1B premature ovarian failure, 1B
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRELID2 PRELI domain containing 2
PRY2 PTPN13-like, Y-linked 2
PTAR1 protein prenyltransferase alpha subunit repeat containing 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
PTN pleiotrophin
PTPRF protein tyrosine phosphatase, receptor type, F
R3HDM2 R3H domain containing 2
RAB19 RAB19, member RAS oncogene family
RAB3IP RAB3A interacting protein
RAD50 RAD50 homolog (S. cerevisiae)
RBKS ribokinase
RBM34 RNA binding motif protein 34
RBPMS RNA binding protein with multiple splicing
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RHPN2 rhophilin, Rho GTPase binding protein 2
RNF185 ring finger protein 185
RNF219 ring finger protein 219
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRM1 ribonucleotide reductase M1
RSC1A1 regulatory solute carrier protein, family 1, member 1
RTCA RNA 3'-terminal phosphate cyclase
RUFY3 RUN and FYVE domain containing 3
SAR1B secretion associated, Ras related GTPase 1B
SCARNA9 small Cajal body-specific RNA 9
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
SEC16B SEC16 homolog B (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC23B Sec23 homolog B (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
SERTAD2 SERTA domain containing 2
SFXN1 sideroflexin 1
SH2D4B SH2 domain containing 4B
SH2D5 SH2 domain containing 5
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHISA9 shisa family member 9
SIRPA signal-regulatory protein alpha
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A13 solute carrier family 16, member 13
SLC16A4 solute carrier family 16, member 4
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC23A3 solute carrier family 23, member 3
SLC25A46 solute carrier family 25, member 46
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC38A4 solute carrier family 38, member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC44A4 solute carrier family 44, member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNORA38 small nucleolar RNA, H/ACA box 38
SNORD116-28 small nucleolar RNA, C/D box 116-28
SNTG2 syntrophin, gamma 2
SNX29 sorting nexin 29
SOAT2 sterol O-acyltransferase 2
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPG11 spastic paraplegia 11 (autosomal recessive)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STX7 syntaxin 7
SYT9 synaptotagmin IX
TADA2B transcriptional adaptor 2B
TAS2R3 taste receptor, type 2, member 3
TBCK TBC1 domain containing kinase
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TLR3 toll-like receptor 3
TM6SF2 transmembrane 6 superfamily member 2
TM7SF3 transmembrane 7 superfamily member 3
TMC4 transmembrane channel-like 4
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM132D transmembrane protein 132D
TMEM144 transmembrane protein 144
TMEM41B transmembrane protein 41B
TMEM51-AS1 TMEM51 antisense RNA 1
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOR1AIP2 torsin A interacting protein 2
TPP1 tripeptidyl peptidase I
TPPP tubulin polymerization promoting protein
TRAP1 TNF receptor-associated protein 1
TREH trehalase (brush-border membrane glycoprotein)
TRIM14 tripartite motif containing 14
TRIM22 tripartite motif containing 22
TRIM34 tripartite motif containing 34
TRIM38 tripartite motif containing 38
TRIM5 tripartite motif containing 5
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM66 tripartite motif containing 66
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSGA10 testis specific, 10
TSPAN18 tetraspanin 18
TTC12 tetratricopeptide repeat domain 12
TTC23 tetratricopeptide repeat domain 23
TTC39A tetratricopeptide repeat domain 39A
TTLL2 tubulin tyrosine ligase-like family member 2
UBA6 ubiquitin-like modifier activating enzyme 6
UBQLN3 ubiquilin 3
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBXN10 UBX domain protein 10
UGP2 UDP-glucose pyrophosphorylase 2
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1
UNC93A unc-93 homolog A (C. elegans)
USP45 ubiquitin specific peptidase 45
USP9Y ubiquitin specific peptidase 9, Y-linked
VIL1 villin 1
VNN1 vanin 1
WAPAL wings apart-like homolog (Drosophila)
WDFY3 WD repeat and FYVE domain containing 3
WDR55 WD repeat domain 55
YIPF6 Yip1 domain family, member 6
ZDHHC5 zinc finger, DHHC-type containing 5
ZFAT zinc finger and AT hook domain containing
ZFYVE26 zinc finger, FYVE domain containing 26
ZMAT4 zinc finger, matrin-type 4
ZNF195 zinc finger protein 195
ZNF214 zinc finger protein 214
ZNF248 zinc finger protein 248
ZNF320 zinc finger protein 320
ZNF33A zinc finger protein 33A
ZNF462 zinc finger protein 462
ZNF827 zinc finger protein 827

low expression

Symbol Name
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ASTE1 asteroid homolog 1 (Drosophila)
C16ORF62 chromosome 16 open reading frame 62
C2ORF44 chromosome 2 open reading frame 44
IFT57 intraflagellar transport 57
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
PDE4A phosphodiesterase 4A, cAMP-specific
RAB12 RAB12, member RAS oncogene family
RYK receptor-like tyrosine kinase
ZNF559 zinc finger protein 559