Interleukin-3, 5 and GM-CSF signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-512988
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Genes

45 proteins participating in the Interleukin-3, 5 and GM-CSF signaling pathway from the Reactome Pathways dataset.

Symbol Name
BLNK B-cell linker
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GRB2 growth factor receptor-bound protein 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HRAS Harvey rat sarcoma viral oncogene homolog
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL3RA interleukin 3 receptor, alpha (low affinity)
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
LYN LYN proto-oncogene, Src family tyrosine kinase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TEC tec protein tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta