Interleukin-1 signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-446652
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Genes

40 proteins participating in the Interleukin-1 signaling pathway from the Reactome Pathways dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CHUK conserved helix-loop-helix ubiquitous kinase
CUL1 cullin 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PELI3 pellino E3 ubiquitin protein ligase family member 3
RBX1 ring-box 1, E3 ubiquitin protein ligase
RIPK2 receptor-interacting serine-threonine kinase 2
SKP1 S-phase kinase-associated protein 1
SQSTM1 sequestosome 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TNIP2 TNFAIP3 interacting protein 2
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1