Interferon gamma signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description Type II interferon, of which there is only one in humans, binds to distinct receptors that activate Jak-Stat signaling pathway. It is known as the interferon gamma signaling. (Pathway Ontology, PW_0000896)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-877300
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Genes

92 proteins participating in the Interferon gamma signaling pathway from the Reactome Pathways dataset.

Symbol Name
B2M beta-2-microglobulin
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD44 CD44 molecule (Indian blood group)
CIITA class II, major histocompatibility complex, transactivator
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GBP6 guanylate binding protein family, member 6
GBP7 guanylate binding protein 7
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ICAM1 intercellular adhesion molecule 1
IFI30 interferon, gamma-inducible protein 30
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF6 interferon regulatory factor 6
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRF9 interferon regulatory factor 9
JAK1 Janus kinase 1
JAK2 Janus kinase 2
MID1 midline 1
MT2A metallothionein 2A
NCAM1 neural cell adhesion molecule 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PIAS1 protein inhibitor of activated STAT, 1
PML promyelocytic leukemia
PRKCD protein kinase C, delta
PTAFR platelet-activating factor receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SP100 SP100 nuclear antigen
STAT1 signal transducer and activator of transcription 1, 91kDa
SUMO1 small ubiquitin-like modifier 1
TRIM10 tripartite motif containing 10
TRIM14 tripartite motif containing 14
TRIM17 tripartite motif containing 17
TRIM2 tripartite motif containing 2
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM26 tripartite motif containing 26
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TRIM31 tripartite motif containing 31
TRIM34 tripartite motif containing 34
TRIM35 tripartite motif containing 35
TRIM38 tripartite motif containing 38
TRIM45 tripartite motif containing 45
TRIM46 tripartite motif containing 46
TRIM48 tripartite motif containing 48
TRIM5 tripartite motif containing 5
TRIM6 tripartite motif containing 6
TRIM62 tripartite motif containing 62
TRIM68 tripartite motif containing 68
TRIM8 tripartite motif containing 8
VCAM1 vascular cell adhesion molecule 1