Interferon Signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-913531
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Genes

194 proteins participating in the Interferon Signaling pathway from the Reactome Pathways dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAR adenosine deaminase, RNA-specific
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
B2M beta-2-microglobulin
BST2 bone marrow stromal cell antigen 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD44 CD44 molecule (Indian blood group)
CIITA class II, major histocompatibility complex, transactivator
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4A3 eukaryotic translation initiation factor 4A3
EIF4E eukaryotic translation initiation factor 4E
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4E3 eukaryotic translation initiation factor 4E family member 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FLNB filamin B, beta
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GBP6 guanylate binding protein family, member 6
GBP7 guanylate binding protein 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI30 interferon, gamma-inducible protein 30
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IP6K2 inositol hexakisphosphate kinase 2
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF6 interferon regulatory factor 6
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KPNA7 karyopherin alpha 7 (importin alpha 8)
KPNB1 karyopherin (importin) beta 1
MAPK3 mitogen-activated protein kinase 3
MID1 midline 1
MT2A metallothionein 2A
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NCAM1 neural cell adhesion molecule 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP160 nucleoporin 160kDa
NUP188 nucleoporin 188kDa
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP214 nucleoporin 214kDa
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
NUP43 nucleoporin 43kDa
NUP50 nucleoporin 50kDa
NUP54 nucleoporin 54kDa
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NUP98 nucleoporin 98kDa
NUPL1 nucleoporin like 1
NUPL2 nucleoporin like 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PIAS1 protein inhibitor of activated STAT, 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG1 phospholipase C, gamma 1
PML promyelocytic leukemia
POM121 POM121 transmembrane nucleoporin
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PRKCD protein kinase C, delta
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTAFR platelet-activating factor receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAE1 ribonucleic acid export 1
RANBP2 RAN binding protein 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS27A ribosomal protein S27a
RSAD2 radical S-adenosyl methionine domain containing 2
SAMHD1 SAM domain and HD domain 1
SEH1L SEH1-like (S. cerevisiae)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SP100 SP100 nuclear antigen
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
SUMO1 small ubiquitin-like modifier 1
TPR translocated promoter region, nuclear basket protein
TRIM10 tripartite motif containing 10
TRIM14 tripartite motif containing 14
TRIM17 tripartite motif containing 17
TRIM2 tripartite motif containing 2
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM26 tripartite motif containing 26
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TRIM31 tripartite motif containing 31
TRIM34 tripartite motif containing 34
TRIM35 tripartite motif containing 35
TRIM38 tripartite motif containing 38
TRIM45 tripartite motif containing 45
TRIM46 tripartite motif containing 46
TRIM48 tripartite motif containing 48
TRIM5 tripartite motif containing 5
TRIM6 tripartite motif containing 6
TRIM62 tripartite motif containing 62
TRIM68 tripartite motif containing 68
TRIM8 tripartite motif containing 8
TYK2 tyrosine kinase 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBB ubiquitin B
UBC ubiquitin C
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
USP18 ubiquitin specific peptidase 18
USP41 ubiquitin specific peptidase 41
VCAM1 vascular cell adhesion molecule 1
XAF1 XIAP associated factor 1