Integrated Pancreatic Cancer Pathway(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP2377_r80437
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Genes

195 proteins participating in the Integrated Pancreatic Cancer Pathway(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
AGA aspartylglucosaminidase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA1 annexin A1
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ATM ATM serine/threonine kinase
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAB39 calcium binding protein 39
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE1 cyclin E1
CD82 CD82 molecule
CDC25C cell division cycle 25C
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAXX death-domain associated protein
DCC DCC netrin 1 receptor
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP3 FK506 binding protein 3, 25kDa
FST follistatin
FTL ferritin, light polypeptide
GADD45A growth arrest and DNA-damage-inducible, alpha
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GTF2A2 general transcription factor IIA, 2, 12kDa
HDAC8 histone deacetylase 8
HNF4A hepatocyte nuclear factor 4, alpha
HPGDS hematopoietic prostaglandin D synthase
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IAPP islet amyloid polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL3 interleukin 3
INHBA inhibin, beta A
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
LEFTY1 left-right determination factor 1
LIG1 ligase I, DNA, ATP-dependent
LTBP1 latent transforming growth factor beta binding protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR3190 microRNA 3190
MIR3191 microRNA 3191
MIR3620 microRNA 3620
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MST1 macrophage stimulating 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYT1 myelin transcription factor 1
NCK1 NCK adaptor protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NME1 NME/NM23 nucleoside diphosphate kinase 1
NODAL nodal growth differentiation factor
NOXA1 NADPH oxidase activator 1
NT5C1A 5'-nucleotidase, cytosolic IA
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNA proliferating cell nuclear antigen
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIAS1 protein inhibitor of activated STAT, 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PITX2 paired-like homeodomain 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLK1 polo-like kinase 1
PLN phospholamban
PML promyelocytic leukemia
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTTG1 pituitary tumor-transforming 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RB1CC1 RB1-inducible coiled-coil 1
RBL1 retinoblastoma-like 1
RHEB Ras homolog enriched in brain
RRM1 ribonucleotide reductase M1
RXRA retinoid X receptor, alpha
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SHH sonic hedgehog
SIRT1 sirtuin 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMO smoothened, frizzled class receptor
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5A signal transducer and activator of transcription 5A
STK11 serine/threonine kinase 11
STMN1 stathmin 1
TBP TATA box binding protein
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TRAF2 TNF receptor-associated factor 2
TYMS thymidylate synthetase
VEGFA vascular endothelial growth factor A
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1