Integrated Breast Cancer Pathway(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP1984_r82941
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Genes

151 proteins participating in the Integrated Breast Cancer Pathway(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANXA1 annexin A1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATF1 activating transcription factor 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CERK ceramide kinase
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
CSNK1D casein kinase 1, delta
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAKD dephospho-CoA kinase domain containing
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
E2F1 E2F transcription factor 1
EDAR ectodysplasin A receptor
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ESR1 estrogen receptor 1
FADD Fas (TNFRSF6)-associated via death domain
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FER fer (fps/fes related) tyrosine kinase
FILIP1 filamin A interacting protein 1
FOXO1 forkhead box O1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDI1 GDP dissociation inhibitor 1
GRIK1-AS2 GRIK1 antisense RNA 2
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
HDAC1 histone deacetylase 1
HIPK2 homeodomain interacting protein kinase 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
IRS1 insulin receptor substrate 1
ITPKC inositol-trisphosphate 3-kinase C
JAK1 Janus kinase 1
JAKMIP1 janus kinase and microtubule interacting protein 1
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS13 lectin, galactoside-binding, soluble, 13
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP3K7CL MAP3K7 C-terminal like
MAPK1 mitogen-activated protein kinase 1
MAX MYC associated factor X
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP1 matrix metallopeptidase 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYT1 myelin transcription factor 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCOA3 nuclear receptor coactivator 3
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOXA1 NADPH oxidase activator 1
NUP85 nucleoporin 85kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PHB prohibitin
PIAS1 protein inhibitor of activated STAT, 1
PIGR polymeric immunoglobulin receptor
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PTEN phosphatase and tensin homolog
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD54L RAD54-like (S. cerevisiae)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAP1A RAP1A, member of RAS oncogene family
RASGEF1A RasGEF domain family, member 1A
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RHEB Ras homolog enriched in brain
RHO rhodopsin
RPP38 ribonuclease P/MRP 38kDa subunit
RRAS related RAS viral (r-ras) oncogene homolog
SELK selenoprotein K
SIRT1 sirtuin 1
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
STK11 serine/threonine kinase 11
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TP53 tumor protein p53
TPR translocated promoter region, nuclear basket protein
TRADD TNFRSF1A-associated via death domain
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBE2F ubiquitin-conjugating enzyme E2F (putative)
USP15 ubiquitin specific peptidase 15
USP16 ubiquitin specific peptidase 16
USP21 ubiquitin specific peptidase 21
USP38 ubiquitin specific peptidase 38
VEGFA vascular endothelial growth factor A
WEE1 WEE1 G2 checkpoint kinase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF655 zinc finger protein 655