Insulin/IGF pathway-protein kinase B signaling cascade Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00033
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Genes

22 proteins participating in the Insulin/IGF pathway-protein kinase B signaling cascade pathway from the PANTHER Pathways dataset.

Symbol Name
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
INSR insulin receptor
INSRR insulin receptor-related receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTEN phosphatase and tensin homolog
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2