Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6678
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Genes

600 genes differentially expressed during Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
FABP5 fatty acid binding protein 5 (psoriasis-associated) 3.48406
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 3.48326
C14ORF166 chromosome 14 open reading frame 166 3.45733
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.44214
UGP2 UDP-glucose pyrophosphorylase 2 3.36721
SET SET nuclear proto-oncogene 3.27199
IFITM3 interferon induced transmembrane protein 3 3.08072
TMX1 thioredoxin-related transmembrane protein 1 2.94826
WBP5 WW domain binding protein 5 2.86842
PTGES3 prostaglandin E synthase 3 (cytosolic) 2.85285
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 2.79271
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 2.71249
RRAGA Ras-related GTP binding A 2.70588
RPS27L ribosomal protein S27-like 2.6689
BEX1 brain expressed, X-linked 1 2.65021
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.64985
EPHX2 epoxide hydrolase 2, cytoplasmic 2.6484
PFN1 profilin 1 2.63747
B2M beta-2-microglobulin 2.5965
SARS seryl-tRNA synthetase 2.56635
CLIC4 chloride intracellular channel 4 2.501
MAGED1 melanoma antigen family D1 2.49122
KDSR 3-ketodihydrosphingosine reductase 2.47762
PARP12 poly (ADP-ribose) polymerase family, member 12 2.47368
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.44295
GCSH glycine cleavage system protein H (aminomethyl carrier) 2.43142
LAPTM4A lysosomal protein transmembrane 4 alpha 2.40169
PQBP1 polyglutamine binding protein 1 2.4003
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 2.38537
CAMTA1 calmodulin binding transcription activator 1 2.37536
HNRNPF heterogeneous nuclear ribonucleoprotein F 2.35816
SRSF6 serine/arginine-rich splicing factor 6 2.34004
RPL5 ribosomal protein L5 2.30358
RPL10A ribosomal protein L10a 2.28747
SAP18 Sin3A-associated protein, 18kDa 2.27284
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.2305
CCT2 chaperonin containing TCP1, subunit 2 (beta) 2.2303
GABARAPL1 GABA(A) receptor-associated protein like 1 2.19924
GABARAP GABA(A) receptor-associated protein 2.17947
CLTA clathrin, light chain A 2.16381
TM2D3 TM2 domain containing 3 2.15911
ITGA6 integrin, alpha 6 2.15486
PKP4 plakophilin 4 2.15095
RPS26 ribosomal protein S26 2.14317
GLO1 glyoxalase I 2.12337
LAPTM4B lysosomal protein transmembrane 4 beta 2.12175
MDK midkine (neurite growth-promoting factor 2) 2.11507
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 2.10762
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 2.10741
PGRMC2 progesterone receptor membrane component 2 2.09387
PMP22 peripheral myelin protein 22 2.09255
VWA1 von Willebrand factor A domain containing 1 2.08992
LXN latexin 2.0868
RPL7A ribosomal protein L7a 2.08557
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 2.08023
PLXNB2 plexin B2 2.0787
FAM8A1 family with sequence similarity 8, member A1 2.05794
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.05311
RBMS1 RNA binding motif, single stranded interacting protein 1 2.03556
EPHB1 EPH receptor B1 2.02373
UBE2N ubiquitin-conjugating enzyme E2N 2.02138
GMPS guanine monphosphate synthase 2.01431
SH3BGRL SH3 domain binding glutamate-rich protein like 2.01294
TCEAL8 transcription elongation factor A (SII)-like 8 2.01243
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 2.01077
TSPAN6 tetraspanin 6 2.01053
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.99306
SHISA5 shisa family member 5 1.99086
M6PR mannose-6-phosphate receptor (cation dependent) 1.98812
TST thiosulfate sulfurtransferase (rhodanese) 1.98761
TOR1AIP2 torsin A interacting protein 2 1.98356
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.97587
SESN3 sestrin 3 1.97288
TMEM165 transmembrane protein 165 1.9716
EIF5B eukaryotic translation initiation factor 5B 1.95363
MRPL24 mitochondrial ribosomal protein L24 1.94321
ZZZ3 zinc finger, ZZ-type containing 3 1.93747
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1.93612
NARS asparaginyl-tRNA synthetase 1.92975
GOLGA7 golgin A7 1.92746
CBFB core-binding factor, beta subunit 1.91243
CCND1 cyclin D1 1.90707
DEK DEK proto-oncogene 1.90312
FGFRL1 fibroblast growth factor receptor-like 1 1.89672
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.89234
PSENEN presenilin enhancer gamma secretase subunit 1.89226
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.88917
TAPBP TAP binding protein (tapasin) 1.87323
DDHD1 DDHD domain containing 1 1.86291
RPL15 ribosomal protein L15 1.85741
SPTSSA serine palmitoyltransferase, small subunit A 1.84026
RPL21 ribosomal protein L21 1.83944
HLA-A major histocompatibility complex, class I, A 1.82901
ELOVL5 ELOVL fatty acid elongase 5 1.82694
EDNRB endothelin receptor type B 1.82464
SYT11 synaptotagmin XI 1.8243
SCPEP1 serine carboxypeptidase 1 1.81928
QDPR quinoid dihydropteridine reductase 1.8181
GATAD2A GATA zinc finger domain containing 2A 1.80217
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.78719
LGALS9B lectin, galactoside-binding, soluble, 9B 1.78621
SLC25A46 solute carrier family 25, member 46 1.78558
ZCCHC12 zinc finger, CCHC domain containing 12 1.78278
DRG1 developmentally regulated GTP binding protein 1 1.7822
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.78052
SSB Sjogren syndrome antigen B (autoantigen La) 1.76608
SDF2 stromal cell-derived factor 2 1.75614
TMEM130 transmembrane protein 130 1.74979
PRDX1 peroxiredoxin 1 1.74923
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 1.74879
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.74674
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.74344
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.73872
ACOT13 acyl-CoA thioesterase 13 1.73683
PCBP1 poly(rC) binding protein 1 1.724
INPP5F inositol polyphosphate-5-phosphatase F 1.72372
HIST1H2BI histone cluster 1, H2bi 1.72207
RAP1B RAP1B, member of RAS oncogene family 1.72142
MORF4L1 mortality factor 4 like 1 1.71572
BCAN brevican 1.7096
PSPH phosphoserine phosphatase 1.70636
ASRGL1 asparaginase like 1 1.70551
LAMP2 lysosomal-associated membrane protein 2 1.70267
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.69744
VTN vitronectin 1.69556
NAF1 nuclear assembly factor 1 ribonucleoprotein 1.69071
HP1BP3 heterochromatin protein 1, binding protein 3 1.68271
FADS2 fatty acid desaturase 2 1.67602
PPAP2B phosphatidic acid phosphatase type 2B 1.67079
CD81 CD81 molecule 1.66624
H2AFY H2A histone family, member Y 1.66578
ATRAID all-trans retinoic acid-induced differentiation factor 1.662
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.66191
CACUL1 CDK2-associated, cullin domain 1 1.6618
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.65822
CCDC47 coiled-coil domain containing 47 1.65292
TCEAL1 transcription elongation factor A (SII)-like 1 1.6515
IER3 immediate early response 3 1.64931
HINT1 histidine triad nucleotide binding protein 1 1.64854
PAQR6 progestin and adipoQ receptor family member VI 1.6477
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1.64361
CLK4 CDC-like kinase 4 1.64341
MYO10 myosin X 1.63847
SRI sorcin 1.63771
KCTD15 potassium channel tetramerization domain containing 15 1.63697
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.63576
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.62722
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.62556
TMEM50A transmembrane protein 50A 1.62512
GM2A GM2 ganglioside activator 1.62249
RPL13 ribosomal protein L13 1.61993
GARS glycyl-tRNA synthetase 1.6198
CCDC107 coiled-coil domain containing 107 1.61966
ZNF384 zinc finger protein 384 1.61738
LDHB lactate dehydrogenase B 1.6148
SBDS Shwachman-Bodian-Diamond syndrome 1.61153
SPARCL1 SPARC-like 1 (hevin) 1.61092
CLK3 CDC-like kinase 3 1.60776
MRPL50 mitochondrial ribosomal protein L50 1.60433
PDCL3 phosducin-like 3 1.59833
EEF2 eukaryotic translation elongation factor 2 1.5962
MED10 mediator complex subunit 10 1.59485
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 1.59149
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.59138
DCAF13 DDB1 and CUL4 associated factor 13 1.59072
TMCO1 transmembrane and coiled-coil domains 1 1.58662
RELL1 RELT-like 1 1.58527
TTC3 tetratricopeptide repeat domain 3 1.58516
SERBP1 SERPINE1 mRNA binding protein 1 1.58481
GRN granulin 1.5827
TJP1 tight junction protein 1 1.57221
FYN FYN proto-oncogene, Src family tyrosine kinase 1.57119
RPL6 ribosomal protein L6 1.56495
CHMP2A charged multivesicular body protein 2A 1.5639
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.55585
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.55546
MED12 mediator complex subunit 12 1.55103
RHOQ ras homolog family member Q 1.55092
FNTA farnesyltransferase, CAAX box, alpha 1.55018
COG3 component of oligomeric golgi complex 3 1.54867
MCL1 myeloid cell leukemia 1 1.54832
LY86 lymphocyte antigen 86 1.54513
SRSF3 serine/arginine-rich splicing factor 3 1.5374
CPNE8 copine VIII 1.53587
STX18 syntaxin 18 1.53404
AQP4 aquaporin 4 1.52612
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.52366
LEPROT leptin receptor overlapping transcript 1.51381
RPL4 ribosomal protein L4 1.50838
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 1.50416
RAB14 RAB14, member RAS oncogene family 1.50041
NTSR2 neurotensin receptor 2 1.49928
ANXA5 annexin A5 1.48714
EIF3D eukaryotic translation initiation factor 3, subunit D 1.48361
GLMP glycosylated lysosomal membrane protein 1.48145
PCNA proliferating cell nuclear antigen 1.47763
SCLY selenocysteine lyase 1.47573
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.47567
PLTP phospholipid transfer protein 1.47424
CDK11A cyclin-dependent kinase 11A 1.47083
IK IK cytokine, down-regulator of HLA II 1.47036
FBRSL1 fibrosin-like 1 1.46639
BMPR1B bone morphogenetic protein receptor, type IB 1.46165
GUSB glucuronidase, beta 1.4603
CAT catalase 1.45375
PLEK pleckstrin 1.4534
SLC38A1 solute carrier family 38, member 1 1.44929
HK2 hexokinase 2 1.44678
IER2 immediate early response 2 1.44435
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.44313
RAB33B RAB33B, member RAS oncogene family 1.44285
RAB11A RAB11A, member RAS oncogene family 1.43915
TOR3A torsin family 3, member A 1.43579
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.43239
PNCK pregnancy up-regulated nonubiquitous CaM kinase 1.43126
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.42835
RPL28 ribosomal protein L28 1.42599
PNP purine nucleoside phosphorylase 1.42289
RNF213 ring finger protein 213 1.42189
IRF9 interferon regulatory factor 9 1.41396
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 1.40805
C5ORF51 chromosome 5 open reading frame 51 1.40759
LGMN legumain 1.40646
BCAP31 B-cell receptor-associated protein 31 1.40336
CUL3 cullin 3 1.4003
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.3964
RPL3 ribosomal protein L3 1.39508
SLC35F5 solute carrier family 35, member F5 1.39165
LIX1L Lix1 homolog (chicken) like 1.38874
STX7 syntaxin 7 1.38667
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.38624
CUL7 cullin 7 1.3856
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.38356
PTPN23 protein tyrosine phosphatase, non-receptor type 23 1.38244
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.38149
HSPE1 heat shock 10kDa protein 1 1.37995
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.37972
GBP4 guanylate binding protein 4 1.3796
SNX8 sorting nexin 8 1.37754
RLBP1 retinaldehyde binding protein 1 1.3768
KDM1A lysine (K)-specific demethylase 1A 1.37342
DSCR3 Down syndrome critical region 3 1.37304
MSN moesin 1.36882
LMBRD1 LMBR1 domain containing 1 1.36486
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 1.3645
RIMKLA ribosomal modification protein rimK-like family member A 1.36279
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.36143
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.35913
FAM134A family with sequence similarity 134, member A 1.35543
RRAGC Ras-related GTP binding C 1.35291
S100A16 S100 calcium binding protein A16 1.35071
C1GALT1C1 C1GALT1-specific chaperone 1 1.34987
NAP1L2 nucleosome assembly protein 1-like 2 1.34472
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.34431
RAP2C RAP2C, member of RAS oncogene family 1.34366
C9ORF64 chromosome 9 open reading frame 64 1.33932
FNIP2 folliculin interacting protein 2 1.33331
CADM4 cell adhesion molecule 4 1.33314
SCAMP2 secretory carrier membrane protein 2 1.33154
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.3312
SRP72 signal recognition particle 72kDa 1.32684
CREG1 cellular repressor of E1A-stimulated genes 1 1.32455
TROVE2 TROVE domain family, member 2 1.32345
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 1.32331
BAX BCL2-associated X protein 1.3185
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.31813
USP39 ubiquitin specific peptidase 39 1.31639
GSK3B glycogen synthase kinase 3 beta 1.31495
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.31124
EPS8 epidermal growth factor receptor pathway substrate 8 1.31037
C1ORF198 chromosome 1 open reading frame 198 1.30694
RPL7 ribosomal protein L7 1.30427
NAMPT nicotinamide phosphoribosyltransferase 1.30411
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.30176
MFAP3L microfibrillar-associated protein 3-like 1.30074
S100A1 S100 calcium binding protein A1 1.30044
PPP1R3C protein phosphatase 1, regulatory subunit 3C 1.29902
LGALS1 lectin, galactoside-binding, soluble, 1 1.29801
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.29396
CTSH cathepsin H 1.28929
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.28799
RPS15A ribosomal protein S15a 1.28773
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.28396
GBP2 guanylate binding protein 2, interferon-inducible 1.28313
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 1.28006
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.27426
BTBD11 BTB (POZ) domain containing 11 1.26992
RPL27 ribosomal protein L27 1.26978
RPL12 ribosomal protein L12 1.26935
TARDBP TAR DNA binding protein 1.26728
RPS27A ribosomal protein S27a 1.26707
H2AFZ H2A histone family, member Z 1.26357
UBXN1 UBX domain protein 1 1.26071
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.26004
CD9 CD9 molecule 1.25794
TRAPPC3 trafficking protein particle complex 3 1.2573
DUSP3 dual specificity phosphatase 3 1.25391
WBP2 WW domain binding protein 2 1.25077
MFSD1 major facilitator superfamily domain containing 1 1.24723
ITPKA inositol-trisphosphate 3-kinase A 1.24361

decreased expression

Symbol Name Standardized Value
WASF1 WAS protein family, member 1 -3.62065
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -3.50177
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -3.40684
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -3.39503
RSF1 remodeling and spacing factor 1 -3.33024
VBP1 von Hippel-Lindau binding protein 1 -3.24234
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -3.24179
OGFRL1 opioid growth factor receptor-like 1 -3.19581
UQCRC2 ubiquinol-cytochrome c reductase core protein II -3.03562
SLITRK5 SLIT and NTRK-like family, member 5 -3.01285
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.97341
SCG5 secretogranin V -2.96607
NCDN neurochondrin -2.92905
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.92104
ANKRD46 ankyrin repeat domain 46 -2.90945
TUBB3 tubulin, beta 3 class III -2.88203
GPR162 G protein-coupled receptor 162 -2.81317
RAB24 RAB24, member RAS oncogene family -2.80932
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 -2.75601
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.75578
ACO2 aconitase 2, mitochondrial -2.73993
PDAP1 PDGFA associated protein 1 -2.72733
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.70965
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -2.68912
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -2.63127
CYB561 cytochrome b561 -2.62484
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -2.60327
PEF1 penta-EF-hand domain containing 1 -2.56831
CELF4 CUGBP, Elav-like family member 4 -2.56429
IRF2BP1 interferon regulatory factor 2 binding protein 1 -2.56148
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.5476
HARS histidyl-tRNA synthetase -2.53275
BAG1 BCL2-associated athanogene -2.52802
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -2.52739
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -2.49912
ARPP21 cAMP-regulated phosphoprotein, 21kDa -2.48652
DUSP26 dual specificity phosphatase 26 (putative) -2.46408
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.46221
DKK3 dickkopf WNT signaling pathway inhibitor 3 -2.45147
BASP1 brain abundant, membrane attached signal protein 1 -2.44564
CLIP3 CAP-GLY domain containing linker protein 3 -2.43066
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.42224
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.41816
AK5 adenylate kinase 5 -2.41379
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -2.39789
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.38108
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.37846
NRSN1 neurensin 1 -2.35899
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 -2.3546
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 -2.35126
KIF3A kinesin family member 3A -2.34791
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.34754
MYEOV2 myeloma overexpressed 2 -2.33721
KIAA0513 KIAA0513 -2.33225
TMEM132A transmembrane protein 132A -2.30175
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -2.28632
GALT galactose-1-phosphate uridylyltransferase -2.27342
CSNK1G2 casein kinase 1, gamma 2 -2.26795
STXBP5 syntaxin binding protein 5 (tomosyn) -2.25692
ARHGAP44 Rho GTPase activating protein 44 -2.25508
ACBD6 acyl-CoA binding domain containing 6 -2.24234
MMP17 matrix metallopeptidase 17 (membrane-inserted) -2.24026
KIAA1324 KIAA1324 -2.22673
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -2.22572
HPCAL4 hippocalcin like 4 -2.22079
EIF5A eukaryotic translation initiation factor 5A -2.21777
GUK1 guanylate kinase 1 -2.21093
CADM1 cell adhesion molecule 1 -2.20679
DCTN1 dynactin 1 -2.20032
TMEM50B transmembrane protein 50B -2.19627
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -2.185
SUB1 SUB1 homolog (S. cerevisiae) -2.18333
PBRM1 polybromo 1 -2.1765
RAB10 RAB10, member RAS oncogene family -2.15627
FAIM2 Fas apoptotic inhibitory molecule 2 -2.15335
ACOT7 acyl-CoA thioesterase 7 -2.15185
SYT13 synaptotagmin XIII -2.14872
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -2.14612
MYO5A myosin VA (heavy chain 12, myoxin) -2.14188
RNPS1 RNA binding protein S1, serine-rich domain -2.13795
HIGD2A HIG1 hypoxia inducible domain family, member 2A -2.13318
GPR83 G protein-coupled receptor 83 -2.12505
WBP4 WW domain binding protein 4 -2.12452
DUSP8 dual specificity phosphatase 8 -2.11512
RAB3A RAB3A, member RAS oncogene family -2.11405
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.1089
TPI1 triosephosphate isomerase 1 -2.1073
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.09956
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.09475
ENSA endosulfine alpha -2.09334
EID2 EP300 interacting inhibitor of differentiation 2 -2.09063
SFSWAP splicing factor, suppressor of white-apricot family -2.0876
MPND MPN domain containing -2.08641
DGKH diacylglycerol kinase, eta -2.08313
C1ORF95 chromosome 1 open reading frame 95 -2.07734
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -2.0706
LMO4 LIM domain only 4 -2.06664
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -2.06077
RAB4A RAB4A, member RAS oncogene family -2.04544
ATL1 atlastin GTPase 1 -2.03585
MYT1L myelin transcription factor 1-like -2.02064
SEPW1 selenoprotein W, 1 -2.01808
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.99884
SYN1 synapsin I -1.98918
GRIA2 glutamate receptor, ionotropic, AMPA 2 -1.98397
DSTN destrin (actin depolymerizing factor) -1.97178
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -1.96918
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -1.96899
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -1.95936
PENK proenkephalin -1.95717
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.95128
C16ORF45 chromosome 16 open reading frame 45 -1.93645
RNF150 ring finger protein 150 -1.9237
EFHD2 EF-hand domain family, member D2 -1.92111
ADRBK1 adrenergic, beta, receptor kinase 1 -1.91785
MRFAP1 Morf4 family associated protein 1 -1.91663
EMC3 ER membrane protein complex subunit 3 -1.91364
STXBP5L syntaxin binding protein 5-like -1.91319
CPLX2 complexin 2 -1.91109
RGS14 regulator of G-protein signaling 14 -1.89882
PCLO piccolo presynaptic cytomatrix protein -1.89844
KIAA1429 KIAA1429 -1.89837
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -1.88631
CAPN7 calpain 7 -1.88147
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.87792
ATXN7L3 ataxin 7-like 3 -1.87471
LYNX1 Ly6/neurotoxin 1 -1.86866
PUM1 pumilio RNA-binding family member 1 -1.86621
PDE2A phosphodiesterase 2A, cGMP-stimulated -1.86503
PCSK5 proprotein convertase subtilisin/kexin type 5 -1.86402
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -1.86124
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -1.85928
CS citrate synthase -1.8585
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.85737
DCTN3 dynactin 3 (p22) -1.85571
NKAIN2 Na+/K+ transporting ATPase interacting 2 -1.85565
TUBB4A tubulin, beta 4A class IVa -1.85362
TEF thyrotrophic embryonic factor -1.85233
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -1.8456
ARF3 ADP-ribosylation factor 3 -1.8423
GSK3A glycogen synthase kinase 3 alpha -1.83582
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -1.83506
TMEM178A transmembrane protein 178A -1.83488
FAM155A family with sequence similarity 155, member A -1.82744
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.81816
RNF145 ring finger protein 145 -1.81806
C22ORF15 chromosome 22 open reading frame 15 -1.8177
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -1.81186
MTX2 metaxin 2 -1.80866
SNAP47 synaptosomal-associated protein, 47kDa -1.80795
STAU2 staufen double-stranded RNA binding protein 2 -1.80495
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.80387
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.79465
AKAP11 A kinase (PRKA) anchor protein 11 -1.79217
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.78687
PPP5C protein phosphatase 5, catalytic subunit -1.78676
GFRA4 GDNF family receptor alpha 4 -1.78522
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -1.78054
DDN dendrin -1.7756
CETN2 centrin, EF-hand protein, 2 -1.77441
GDE1 glycerophosphodiester phosphodiesterase 1 -1.774
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.77237
TESC tescalcin -1.77175
ZMYND11 zinc finger, MYND-type containing 11 -1.77016
MAP2K1 mitogen-activated protein kinase kinase 1 -1.76981
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -1.76149
CLSTN1 calsyntenin 1 -1.76105
SEC63 SEC63 homolog (S. cerevisiae) -1.75723
MTMR12 myotubularin related protein 12 -1.75444
CNIH2 cornichon family AMPA receptor auxiliary protein 2 -1.74958
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -1.74709
MSRA methionine sulfoxide reductase A -1.74564
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -1.7421
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -1.74126
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -1.73941
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -1.73596
MMD monocyte to macrophage differentiation-associated -1.72882
FAM65B family with sequence similarity 65, member B -1.72743
SMAP2 small ArfGAP2 -1.72718
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -1.72603
VIP vasoactive intestinal peptide -1.71928
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.71573
RIMS1 regulating synaptic membrane exocytosis 1 -1.71293
COX4I1 cytochrome c oxidase subunit IV isoform 1 -1.71177
COPS8 COP9 signalosome subunit 8 -1.71055
COA5 cytochrome c oxidase assembly factor 5 -1.70984
GRIA3 glutamate receptor, ionotropic, AMPA 3 -1.70118
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -1.68739
TUBA1A tubulin, alpha 1a -1.68612
FBXO45 F-box protein 45 -1.68089
ADGRL1 adhesion G protein-coupled receptor L1 -1.67562
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -1.67098
RAP1GAP2 RAP1 GTPase activating protein 2 -1.66776
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -1.66648
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -1.66593
ZNF23 zinc finger protein 23 -1.66495
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -1.66288
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -1.65777
OLFM1 olfactomedin 1 -1.65466
PDE1B phosphodiesterase 1B, calmodulin-dependent -1.65407
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.64726
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -1.63743
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -1.6366
DCLK3 doublecortin-like kinase 3 -1.63547
CAMK1D calcium/calmodulin-dependent protein kinase ID -1.63371
DCTN5 dynactin 5 (p25) -1.63331
SV2B synaptic vesicle glycoprotein 2B -1.62945
STOML2 stomatin (EPB72)-like 2 -1.62736
ELMO2 engulfment and cell motility 2 -1.62541
IFT74 intraflagellar transport 74 -1.62255
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -1.62233
SCAF11 SR-related CTD-associated factor 11 -1.61423
PCDH19 protocadherin 19 -1.60965
STRN striatin, calmodulin binding protein -1.60958
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.59101
SEPT3 septin 3 -1.59054
TMOD2 tropomodulin 2 (neuronal) -1.58641
EXOC6B exocyst complex component 6B -1.58573
TTC19 tetratricopeptide repeat domain 19 -1.58302
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.58293
MTFP1 mitochondrial fission process 1 -1.57854
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -1.57741
FAM173A family with sequence similarity 173, member A -1.5762
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -1.57276
KIF3C kinesin family member 3C -1.57047
TMEM68 transmembrane protein 68 -1.5674
BMS1 BMS1 ribosome biogenesis factor -1.56699
GPR155 G protein-coupled receptor 155 -1.56661
ACSL5 acyl-CoA synthetase long-chain family member 5 -1.56615
CTNND2 catenin (cadherin-associated protein), delta 2 -1.56581
SECISBP2L SECIS binding protein 2-like -1.56508
PPT1 palmitoyl-protein thioesterase 1 -1.5627
MTCH1 mitochondrial carrier 1 -1.56237
NRG3 neuregulin 3 -1.56003
DAPK1 death-associated protein kinase 1 -1.55968
ADGRB3 adhesion G protein-coupled receptor B3 -1.55936
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -1.55791
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.55115
NT5DC3 5'-nucleotidase domain containing 3 -1.54856
PTPRG protein tyrosine phosphatase, receptor type, G -1.54691
PGAM5 phosphoglycerate mutase family member 5 -1.54107
RNF112 ring finger protein 112 -1.53937
GLRX5 glutaredoxin 5 -1.53789
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.53686
FBXO31 F-box protein 31 -1.5306
SUCLG1 succinate-CoA ligase, alpha subunit -1.5254
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.52373
RUNDC3A RUN domain containing 3A -1.52269
SMG5 SMG5 nonsense mediated mRNA decay factor -1.51841
ZDHHC14 zinc finger, DHHC-type containing 14 -1.51512
LY6H lymphocyte antigen 6 complex, locus H -1.51291
PCNP PEST proteolytic signal containing nuclear protein -1.50993
CFL1 cofilin 1 (non-muscle) -1.50459
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -1.50384
SNX17 sorting nexin 17 -1.50249
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -1.50085
CHM choroideremia (Rab escort protein 1) -1.49893
RASGEF1A RasGEF domain family, member 1A -1.49733
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.4959
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -1.49426
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -1.48899
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -1.48839
EFR3A EFR3 homolog A (S. cerevisiae) -1.48628
KCTD17 potassium channel tetramerization domain containing 17 -1.48598
GRM5 glutamate receptor, metabotropic 5 -1.48466
NT5C 5', 3'-nucleotidase, cytosolic -1.48225
KLHL26 kelch-like family member 26 -1.47908
MAGEE1 melanoma antigen family E1 -1.47602
USP22 ubiquitin specific peptidase 22 -1.4741
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -1.46642
PLXNA2 plexin A2 -1.46345
BTBD10 BTB (POZ) domain containing 10 -1.4606
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.45985
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -1.45928
ACVR2A activin A receptor, type IIA -1.4582
BEND6 BEN domain containing 6 -1.45681
DLG3 discs, large homolog 3 (Drosophila) -1.45625
PPP1R3F protein phosphatase 1, regulatory subunit 3F -1.45508
TMTC4 transmembrane and tetratricopeptide repeat containing 4 -1.45193
THOC2 THO complex 2 -1.45166
ADGRB2 adhesion G protein-coupled receptor B2 -1.44868
FAM126B family with sequence similarity 126, member B -1.44793
TRIM32 tripartite motif containing 32 -1.44684
COPE coatomer protein complex, subunit epsilon -1.44501
FBXO41 F-box protein 41 -1.44435
SUMO2 small ubiquitin-like modifier 2 -1.44122
SEC23B Sec23 homolog B (S. cerevisiae) -1.4403
DPP10 dipeptidyl-peptidase 10 (non-functional) -1.44026
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.43334
USP46 ubiquitin specific peptidase 46 -1.43318
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.43312
NAP1L4 nucleosome assembly protein 1-like 4 -1.43253
AKIRIN1 akirin 1 -1.43093
PTBP2 polypyrimidine tract binding protein 2 -1.43027
OCIAD2 OCIA domain containing 2 -1.4301
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.42952
RGS7 regulator of G-protein signaling 7 -1.42868
TUSC2 tumor suppressor candidate 2 -1.42657
RNASEH2C ribonuclease H2, subunit C -1.42507
VMP1 vacuole membrane protein 1 -1.42487