IgE levels Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A serum immunoglobulin E measurement is the measurement of the IgE antibody isotype produced by plasma cells in response to an immunogen and which function as antibodies, measured in serum. IgE's main function is immunity to parasites such as parasitic worms and it plays an essential role in the allergy disorder, and is especially associated with type I hypersensitivity. (Experimental Factor Ontology, EFO_0004579)
External Link https://www.ebi.ac.uk/gwas/search?query=IgE levels
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9 genes associated with the IgE levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.19355
IL13 interleukin 13 0.969518
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.637972
RAD50 RAD50 homolog (S. cerevisiae) 0.377988
IL4R interleukin 4 receptor 0.342586
LINC00299 long intergenic non-protein coding RNA 299 0.314454
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.220915
LPP LIM domain containing preferred translocation partner in lipoma 0.165905
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.085234