Ibuprofen Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. (Chemical Entities of Biological Interest Ontology, CHEBI_5855)
External Link http://ctdbase.org/detail.go?type=chem&acc=D007052
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Genes

109 genes/proteins interacting with the chemical Ibuprofen from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL6 acyl-CoA synthetase long-chain family member 6
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
AMACR alpha-methylacyl-CoA racemase
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ASIC1 acid sensing (proton gated) ion channel 1
BACE1 beta-site APP-cleaving enzyme 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHUK conserved helix-loop-helix ubiquitous kinase
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL2 chemokine (C-X-C motif) ligand 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
EGF epidermal growth factor
EIF4E eukaryotic translation initiation factor 4E
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
EPAS1 endothelial PAS domain protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FAAH fatty acid amide hydrolase
FASN fatty acid synthase
GDF15 growth differentiation factor 15
GSTT1 glutathione S-transferase theta 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LTA lymphotoxin alpha
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NOS2 nitric oxide synthase 2, inducible
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PABPN1 poly(A) binding protein, nuclear 1
PGAM1 phosphoglycerate mutase 1 (brain)
PLEC plectin
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRDX2 peroxiredoxin 2
PRDX6 peroxiredoxin 6
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXN paxillin
RAN RAN, member RAS oncogene family
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SELE selectin E
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC22A8 solute carrier family 22 (organic anion transporter), member 8
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPI1 triosephosphate isomerase 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A