Ibrutinib_Ramos (RA 1) Gene Set

Dataset LINCS Kinativ Kinase Inhibitor Bioactivity Profiles
Category physical interactions
Type chemical bioactivity profile
Description kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name] (LINCS Kinativ)
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Genes

9 kinases with high inhibition of kinase activity in the Ibrutinib_Ramos (RA 1) chemical bioactivity profile from the Kinativ Kinase Inhibitor Bioactivity Profiles dataset.

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 0.496483

Symbol Name Standardized Value
ATR ATR serine/threonine kinase -0.399657
TBK1 TANK-binding kinase 1 -0.336788
STK10 serine/threonine kinase 10 -0.298329
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.293127
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.293127
CDK8 cyclin-dependent kinase 8 -0.249271
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.246534
JAK1 Janus kinase 1 -0.20345