Hypertrophy, Left Ventricular_Myocardial tissue_GSE2459 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2459
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Genes

600 genes differentially expressed during Hypertrophy, Left Ventricular_Myocardial tissue_GSE2459 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 3.77525
ACTA1 actin, alpha 1, skeletal muscle 3.67891
FBL fibrillarin 3.35227
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3.30127
S100A13 S100 calcium binding protein A13 3.21187
UGP2 UDP-glucose pyrophosphorylase 2 3.02586
HTT huntingtin 2.96441
POLM polymerase (DNA directed), mu 2.95206
MFGE8 milk fat globule-EGF factor 8 protein 2.85869
PNKD paroxysmal nonkinesigenic dyskinesia 2.79388
CARHSP1 calcium regulated heat stable protein 1, 24kDa 2.79007
STAT5A signal transducer and activator of transcription 5A 2.78247
C17ORF62 chromosome 17 open reading frame 62 2.77764
GSTO1 glutathione S-transferase omega 1 2.74962
GAMT guanidinoacetate N-methyltransferase 2.74774
SVIL supervillin 2.68096
NRAP nebulin-related anchoring protein 2.67393
GOLGA3 golgin A3 2.6679
AP3B1 adaptor-related protein complex 3, beta 1 subunit 2.64383
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.62088
SOD3 superoxide dismutase 3, extracellular 2.62035
NPDC1 neural proliferation, differentiation and control, 1 2.54665
NPPA natriuretic peptide A 2.53592
PABPC1 poly(A) binding protein, cytoplasmic 1 2.53548
LIMA1 LIM domain and actin binding 1 2.53051
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 2.52532
HBEGF heparin-binding EGF-like growth factor 2.5179
DYNLL2 dynein, light chain, LC8-type 2 2.44383
SYNGR1 synaptogyrin 1 2.43668
GLTP glycolipid transfer protein 2.4177
BAG2 BCL2-associated athanogene 2 2.41281
IGF1R insulin-like growth factor 1 receptor 2.4027
SLC38A5 solute carrier family 38, member 5 2.38544
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.32631
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.31974
GOLGA4 golgin A4 2.31586
CTGF connective tissue growth factor 2.30556
GLRX glutaredoxin (thioltransferase) 2.29462
EVX2 even-skipped homeobox 2 2.28041
FBLN2 fibulin 2 2.27749
HAUS8 HAUS augmin-like complex, subunit 8 2.25159
MYBPC3 myosin binding protein C, cardiac 2.24902
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.24595
XIRP1 xin actin binding repeat containing 1 2.23108
DCN decorin 2.22617
DYNLL1 dynein, light chain, LC8-type 1 2.22538
BGN biglycan 2.22079
PRNP prion protein 2.21693
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 2.19993
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.18772
ANXA2 annexin A2 2.18749
COL4A2 collagen, type IV, alpha 2 2.16636
TNPO2 transportin 2 2.15664
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 2.15061
RNH1 ribonuclease/angiogenin inhibitor 1 2.12872
PRKCDBP protein kinase C, delta binding protein 2.11493
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.11024
CSF3 colony stimulating factor 3 (granulocyte) 2.10736
CD9 CD9 molecule 2.0919
COL8A1 collagen, type VIII, alpha 1 2.08165
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.08042
FADS1 fatty acid desaturase 1 2.06379
MVP major vault protein 2.05968
GM2A GM2 ganglioside activator 2.05153
LRP1 low density lipoprotein receptor-related protein 1 2.0401
HOXB7 homeobox B7 2.009
MEMO1 mediator of cell motility 1 2.00655
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.00417
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.98866
GRID1 glutamate receptor, ionotropic, delta 1 1.96619
ABHD16A abhydrolase domain containing 16A 1.96304
BTF3 basic transcription factor 3 1.94959
GRWD1 glutamate-rich WD repeat containing 1 1.94771
CEP350 centrosomal protein 350kDa 1.94747
GPX3 glutathione peroxidase 3 1.94326
CKS2 CDC28 protein kinase regulatory subunit 2 1.93947
PPA1 pyrophosphatase (inorganic) 1 1.93004
LUM lumican 1.92517
UCK2 uridine-cytidine kinase 2 1.92164
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.92091
ITGB5 integrin, beta 5 1.92001
C11ORF42 chromosome 11 open reading frame 42 1.91143
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 1.9086
KLF3 Kruppel-like factor 3 (basic) 1.90412
IL6ST interleukin 6 signal transducer 1.90037
CTSD cathepsin D 1.89795
MFAP5 microfibrillar associated protein 5 1.89749
TNIP1 TNFAIP3 interacting protein 1 1.89427
PCOLCE procollagen C-endopeptidase enhancer 1.89352
CSAD cysteine sulfinic acid decarboxylase 1.88303
TGM2 transglutaminase 2 1.87961
CLIP1 CAP-GLY domain containing linker protein 1 1.87018
MAN2A1 mannosidase, alpha, class 2A, member 1 1.8638
LARS leucyl-tRNA synthetase 1.85648
DQX1 DEAQ box RNA-dependent ATPase 1 1.84878
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 1.84645
CTRB2 chymotrypsinogen B2 1.82678
SQSTM1 sequestosome 1 1.81251
GRB10 growth factor receptor-bound protein 10 1.8053
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 1.79642
HIST1H3F histone cluster 1, H3f 1.79238
TSPO translocator protein (18kDa) 1.78921
PTPRN protein tyrosine phosphatase, receptor type, N 1.77167
ANXA3 annexin A3 1.76727
ASS1 argininosuccinate synthase 1 1.76719
SLMAP sarcolemma associated protein 1.76493
PCSK6 proprotein convertase subtilisin/kexin type 6 1.7617
MIIP migration and invasion inhibitory protein 1.75673
LGALS1 lectin, galactoside-binding, soluble, 1 1.7526
ACOT9 acyl-CoA thioesterase 9 1.75192
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.74529
EIF3A eukaryotic translation initiation factor 3, subunit A 1.74272
ETF1 eukaryotic translation termination factor 1 1.74262
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 1.74218
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 1.74109
TRIM41 tripartite motif containing 41 1.73752
ZYG11B zyg-11 family member B, cell cycle regulator 1.73006
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.71364
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 1.70674
LRRC59 leucine rich repeat containing 59 1.70174
IL1R2 interleukin 1 receptor, type II 1.70029
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.69883
UBQLN4 ubiquilin 4 1.69848
SLMO2 slowmo homolog 2 (Drosophila) 1.6918
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.6889
F2R coagulation factor II (thrombin) receptor 1.68787
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.68421
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.67215
TSSC4 tumor suppressing subtransferable candidate 4 1.66714
SOCS5 suppressor of cytokine signaling 5 1.66277
NFE2L1 nuclear factor, erythroid 2-like 1 1.66153
ZNF131 zinc finger protein 131 1.66089
BHMT betaine--homocysteine S-methyltransferase 1.65872
C9ORF3 chromosome 9 open reading frame 3 1.65865
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.64954
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.64795
C1ORF158 chromosome 1 open reading frame 158 1.6472
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.64701
OSBP oxysterol binding protein 1.64235
GAB2 GRB2-associated binding protein 2 1.64109
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.63752
ADPRH ADP-ribosylarginine hydrolase 1.63631
DPF2 D4, zinc and double PHD fingers family 2 1.6345
ESD esterase D 1.63233
TSPYL1 TSPY-like 1 1.63228
POSTN periostin, osteoblast specific factor 1.63113
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1.62871
MCRS1 microspherule protein 1 1.62208
PFKL phosphofructokinase, liver 1.62012
TUBB tubulin, beta class I 1.61866
ABI1 abl-interactor 1 1.61421
TUBB2A tubulin, beta 2A class IIa 1.61246
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.60746
ZMYM4 zinc finger, MYM-type 4 1.60543
INTS4 integrator complex subunit 4 1.60486
CAB39 calcium binding protein 39 1.59962
CDV3 CDV3 homolog (mouse) 1.59911
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 1.5959
RASIP1 Ras interacting protein 1 1.59037
RHOA ras homolog family member A 1.58905
UBE2H ubiquitin-conjugating enzyme E2H 1.58175
CKB creatine kinase, brain 1.58163
SBDS Shwachman-Bodian-Diamond syndrome 1.57809
KRT35 keratin 35, type I 1.57181
TPRG1L tumor protein p63 regulated 1-like 1.56939
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.56887
PGM1 phosphoglucomutase 1 1.56746
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.56569
GUCA2B guanylate cyclase activator 2B (uroguanylin) 1.56225
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.56155
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.55993
PEX14 peroxisomal biogenesis factor 14 1.55746
RBP1 retinol binding protein 1, cellular 1.5573
PHF23 PHD finger protein 23 1.55718
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.55344
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.55247
HSPA4L heat shock 70kDa protein 4-like 1.54709
NADK NAD kinase 1.54491
NAE1 NEDD8 activating enzyme E1 subunit 1 1.53899
RPL3 ribosomal protein L3 1.53635
MYO9A myosin IXA 1.53616
HIC1 hypermethylated in cancer 1 1.53451
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.53135
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.52962
COL1A2 collagen, type I, alpha 2 1.52779
CDK11A cyclin-dependent kinase 11A 1.52334
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.52062
TWF2 twinfilin actin binding protein 2 1.51984
RBM18 RNA binding motif protein 18 1.51828
COL1A1 collagen, type I, alpha 1 1.51809
CUL3 cullin 3 1.51471
LHB luteinizing hormone beta polypeptide 1.51318
CTSK cathepsin K 1.512
POMP proteasome maturation protein 1.48996
CSNK1D casein kinase 1, delta 1.48991
TLN1 talin 1 1.48653
BMP6 bone morphogenetic protein 6 1.4814
GFER growth factor, augmenter of liver regeneration 1.47096
ZNF622 zinc finger protein 622 1.46924
PDLIM1 PDZ and LIM domain 1 1.4662
PRPF6 pre-mRNA processing factor 6 1.46617
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.46555
C5ORF15 chromosome 5 open reading frame 15 1.46257
DHRSX dehydrogenase/reductase (SDR family) X-linked 1.46191
KIF5B kinesin family member 5B 1.46089
VPRBP Vpr (HIV-1) binding protein 1.46079
MYDGF myeloid-derived growth factor 1.45618
CD34 CD34 molecule 1.45516
ACTC1 actin, alpha, cardiac muscle 1 1.45481
ACR acrosin 1.45432
CIAPIN1 cytokine induced apoptosis inhibitor 1 1.45279
LOXL1 lysyl oxidase-like 1 1.45116
MAB21L2 mab-21-like 2 (C. elegans) 1.4509
BAK1 BCL2-antagonist/killer 1 1.44646
GABARAPL1 GABA(A) receptor-associated protein like 1 1.44598
FAM32A family with sequence similarity 32, member A 1.44543
PGS1 phosphatidylglycerophosphate synthase 1 1.43919
TEX264 testis expressed 264 1.4378
TLK2 tousled-like kinase 2 1.43778
TTC7B tetratricopeptide repeat domain 7B 1.43757
EXOC4 exocyst complex component 4 1.43643
TIMP3 TIMP metallopeptidase inhibitor 3 1.43575
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1.43529
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1.4346
WDR45 WD repeat domain 45 1.43363
TIGD5 tigger transposable element derived 5 1.43328
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 1.42701
COL6A3 collagen, type VI, alpha 3 1.41994
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 1.41952
ERLIN1 ER lipid raft associated 1 1.41925
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41643
JAK3 Janus kinase 3 1.41454
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.41083
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.40934
ISCU iron-sulfur cluster assembly enzyme 1.40807
MRPL1 mitochondrial ribosomal protein L1 1.40514
BAG3 BCL2-associated athanogene 3 1.40229
BRAP BRCA1 associated protein 1.40026
CPXM2 carboxypeptidase X (M14 family), member 2 1.39997
HDAC7 histone deacetylase 7 1.39509
INPPL1 inositol polyphosphate phosphatase-like 1 1.39128
ZNF32 zinc finger protein 32 1.38808
PDE4DIP phosphodiesterase 4D interacting protein 1.3836
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.38313
PARD6G par-6 family cell polarity regulator gamma 1.38276
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.38049
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.3777
PLAC8 placenta-specific 8 1.37355
TCF4 transcription factor 4 1.37234
GJB5 gap junction protein, beta 5, 31.1kDa 1.37128
LY9 lymphocyte antigen 9 1.36967
DCTN3 dynactin 3 (p22) 1.36679
FXYD1 FXYD domain containing ion transport regulator 1 1.36426
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.35893
PRSS1 protease, serine, 1 (trypsin 1) 1.35158
RAB33B RAB33B, member RAS oncogene family 1.34733
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.34165
ILK integrin-linked kinase 1.34152
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 1.33732
GSR glutathione reductase 1.33697
AKIRIN2 akirin 2 1.33665
NCL nucleolin 1.33632
IGFBP6 insulin-like growth factor binding protein 6 1.33582
NAP1L1 nucleosome assembly protein 1-like 1 1.33511
YAP1 Yes-associated protein 1 1.33338
COMT catechol-O-methyltransferase 1.33179
NKIRAS1 NFKB inhibitor interacting Ras-like 1 1.33155
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.33154
GDI2 GDP dissociation inhibitor 2 1.33125
C2 complement component 2 1.33092
CAPNS1 calpain, small subunit 1 1.32868
IRF1 interferon regulatory factor 1 1.32584
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.32575
FBLN1 fibulin 1 1.32284
PCYOX1 prenylcysteine oxidase 1 1.32229
ARF1 ADP-ribosylation factor 1 1.31994
OSTF1 osteoclast stimulating factor 1 1.31801
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.31706
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.31572
CARS cysteinyl-tRNA synthetase 1.30845
FSTL1 follistatin-like 1 1.30755
SUN2 Sad1 and UNC84 domain containing 2 1.30751
BIK BCL2-interacting killer (apoptosis-inducing) 1.30502
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.30422
EIF4A2 eukaryotic translation initiation factor 4A2 1.30101
PES1 pescadillo ribosomal biogenesis factor 1 1.29936
EMP2 epithelial membrane protein 2 1.29656
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.29573
RAB6A RAB6A, member RAS oncogene family 1.29477
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.29468
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 1.29289
RHOD ras homolog family member D 1.2905
CCL22 chemokine (C-C motif) ligand 22 1.28946
SLC48A1 solute carrier family 48 (heme transporter), member 1 1.28843
GRK5 G protein-coupled receptor kinase 5 1.28363
LPP LIM domain containing preferred translocation partner in lipoma 1.27978
RSU1 Ras suppressor protein 1 1.27958
LARP1 La ribonucleoprotein domain family, member 1 1.27922
TXNDC16 thioredoxin domain containing 16 1.2792
TP53INP2 tumor protein p53 inducible nuclear protein 2 1.27657

decreased expression

Symbol Name Standardized Value
ENO3 enolase 3 (beta, muscle) -4.01032
WNK2 WNK lysine deficient protein kinase 2 -3.77885
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -3.73471
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -3.62238
LAMA5 laminin, alpha 5 -3.53903
ANAPC13 anaphase promoting complex subunit 13 -3.15302
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -3.07347
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -3.04271
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.9248
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.91093
MRPS36 mitochondrial ribosomal protein S36 -2.90179
GBAS glioblastoma amplified sequence -2.88231
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 -2.87161
REEP5 receptor accessory protein 5 -2.79672
RAX retina and anterior neural fold homeobox -2.77942
AMZ2 archaelysin family metallopeptidase 2 -2.73808
GLRA1 glycine receptor, alpha 1 -2.73319
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.73276
C7ORF55 chromosome 7 open reading frame 55 -2.72991
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -2.72828
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.71479
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.69983
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.69757
MLX MLX, MAX dimerization protein -2.68209
GMFG glia maturation factor, gamma -2.66333
C12ORF57 chromosome 12 open reading frame 57 -2.65636
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -2.63417
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.63274
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.60611
NFU1 NFU1 iron-sulfur cluster scaffold -2.60488
BRCA2 breast cancer 2, early onset -2.59618
ACAA2 acetyl-CoA acyltransferase 2 -2.58821
POU2F3 POU class 2 homeobox 3 -2.55958
GSTK1 glutathione S-transferase kappa 1 -2.55829
GSTM5 glutathione S-transferase mu 5 -2.55409
ECH1 enoyl CoA hydratase 1, peroxisomal -2.55354
RBM38 RNA binding motif protein 38 -2.50792
CD99L2 CD99 molecule-like 2 -2.48138
IPO11 importin 11 -2.46582
FCHO1 FCH domain only 1 -2.46319
FAM102A family with sequence similarity 102, member A -2.45308
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -2.44982
PHYH phytanoyl-CoA 2-hydroxylase -2.43943
CRAT carnitine O-acetyltransferase -2.43836
ZC3H3 zinc finger CCCH-type containing 3 -2.43283
MCEE methylmalonyl CoA epimerase -2.4297
PXMP2 peroxisomal membrane protein 2, 22kDa -2.39065
AUH AU RNA binding protein/enoyl-CoA hydratase -2.38995
MRPL41 mitochondrial ribosomal protein L41 -2.37447
HOPX HOP homeobox -2.36861
ERP29 endoplasmic reticulum protein 29 -2.35605
CSNK2B casein kinase 2, beta polypeptide -2.34784
CLK3 CDC-like kinase 3 -2.34303
CHAD chondroadherin -2.3418
GAL galanin/GMAP prepropeptide -2.34138
SDF2 stromal cell-derived factor 2 -2.30986
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.30654
PRDX5 peroxiredoxin 5 -2.30565
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.30485
MFSD5 major facilitator superfamily domain containing 5 -2.3021
STAB1 stabilin 1 -2.30186
ETFB electron-transfer-flavoprotein, beta polypeptide -2.29135
STAR steroidogenic acute regulatory protein -2.29124
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.26704
SEC61B Sec61 beta subunit -2.25587
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 -2.22688
SMAGP small cell adhesion glycoprotein -2.21774
RANBP10 RAN binding protein 10 -2.20169
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.20104
TMEM14C transmembrane protein 14C -2.19912
CA4 carbonic anhydrase IV -2.19696
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.1953
HINT2 histidine triad nucleotide binding protein 2 -2.18921
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.17964
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -2.17724
PLBD1 phospholipase B domain containing 1 -2.1692
ANKH ANKH inorganic pyrophosphate transport regulator -2.16763
VEGFB vascular endothelial growth factor B -2.16168
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.15817
PHOSPHO1 phosphatase, orphan 1 -2.14783
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -2.1405
ACOT7 acyl-CoA thioesterase 7 -2.13527
PFKM phosphofructokinase, muscle -2.1248
XPA xeroderma pigmentosum, complementation group A -2.11152
BPIFA2 BPI fold containing family A, member 2 -2.10788
GAB1 GRB2-associated binding protein 1 -2.09172
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.08423
DDHD2 DDHD domain containing 2 -2.07733
RGS3 regulator of G-protein signaling 3 -2.07618
YME1L1 YME1-like 1 ATPase -2.07494
CYC1 cytochrome c-1 -2.07107
SRPK1 SRSF protein kinase 1 -2.06964
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -2.06342
IFNB1 interferon, beta 1, fibroblast -2.04783
TRAPPC1 trafficking protein particle complex 1 -2.04551
AES amino-terminal enhancer of split -2.04339
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -2.03364
ADCY9 adenylate cyclase 9 -2.02936
TXN2 thioredoxin 2 -2.02013
AMH anti-Mullerian hormone -2.01864
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.0085
TMEM70 transmembrane protein 70 -2.00365
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -1.99383
HSPB11 heat shock protein family B (small), member 11 -1.98509
ASNS asparagine synthetase (glutamine-hydrolyzing) -1.97695
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.97637
PPP6R3 protein phosphatase 6, regulatory subunit 3 -1.97034
HABP2 hyaluronan binding protein 2 -1.96477
RAD23B RAD23 homolog B (S. cerevisiae) -1.9625
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.95198
NUP85 nucleoporin 85kDa -1.93738
F2RL2 coagulation factor II (thrombin) receptor-like 2 -1.9291
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -1.91978
FLCN folliculin -1.91489
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.91172
C6ORF89 chromosome 6 open reading frame 89 -1.90863
ALAD aminolevulinate dehydratase -1.90204
OAT ornithine aminotransferase -1.89493
ORC4 origin recognition complex, subunit 4 -1.89433
KIAA0100 KIAA0100 -1.89196
ADRBK1 adrenergic, beta, receptor kinase 1 -1.889
MEP1B meprin A, beta -1.88595
GTF2I general transcription factor IIi -1.88334
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.87264
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.87088
FAM195B family with sequence similarity 195, member B -1.86878
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -1.86129
MMP14 matrix metallopeptidase 14 (membrane-inserted) -1.85731
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -1.85664
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.8526
SEZ6L seizure related 6 homolog (mouse)-like -1.85224
MRPL45 mitochondrial ribosomal protein L45 -1.85114
MYL2 myosin, light chain 2, regulatory, cardiac, slow -1.84727
SYT11 synaptotagmin XI -1.84607
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -1.84088
SNIP1 Smad nuclear interacting protein 1 -1.83877
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -1.83747
CCDC93 coiled-coil domain containing 93 -1.82591
STC2 stanniocalcin 2 -1.8258
COQ9 coenzyme Q9 -1.82475
CAB39L calcium binding protein 39-like -1.82045
ERP44 endoplasmic reticulum protein 44 -1.81721
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -1.81702
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -1.81486
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -1.81428
ISOC1 isochorismatase domain containing 1 -1.81226
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.80974
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -1.80269
RYK receptor-like tyrosine kinase -1.79706
STK24 serine/threonine kinase 24 -1.79671
RPS2 ribosomal protein S2 -1.79298
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -1.78828
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -1.78626
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha -1.77516
RAG1 recombination activating gene 1 -1.77416
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.76213
EFNB3 ephrin-B3 -1.76012
CSNK1G2 casein kinase 1, gamma 2 -1.7569
OMP olfactory marker protein -1.75514
CBFB core-binding factor, beta subunit -1.7516
EIF4E eukaryotic translation initiation factor 4E -1.75001
PPIF peptidylprolyl isomerase F -1.74814
ACYP2 acylphosphatase 2, muscle type -1.74765
RYR2 ryanodine receptor 2 (cardiac) -1.74722
APOA1 apolipoprotein A-I -1.74372
RNF167 ring finger protein 167 -1.74282
IL10RB interleukin 10 receptor, beta -1.73754
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -1.73631
HTRA1 HtrA serine peptidase 1 -1.72488
HDLBP high density lipoprotein binding protein -1.72335
HMBS hydroxymethylbilane synthase -1.71842
FLT3 fms-related tyrosine kinase 3 -1.71667
POLD2 polymerase (DNA directed), delta 2, accessory subunit -1.71537
SRSF9 serine/arginine-rich splicing factor 9 -1.71518
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -1.71281
LPL lipoprotein lipase -1.71029
ICA1 islet cell autoantigen 1, 69kDa -1.70293
ECI1 enoyl-CoA delta isomerase 1 -1.70185
UBN1 ubinuclein 1 -1.69832
NEFL neurofilament, light polypeptide -1.69702
ADCY6 adenylate cyclase 6 -1.69319
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.69063
LGALS4 lectin, galactoside-binding, soluble, 4 -1.68977
METTL8 methyltransferase like 8 -1.68593
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -1.68545
PRUNE prune exopolyphosphatase -1.67893
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -1.67782
WDR75 WD repeat domain 75 -1.67068
CDK7 cyclin-dependent kinase 7 -1.66461
EGFL8 EGF-like-domain, multiple 8 -1.66347
PIAS2 protein inhibitor of activated STAT, 2 -1.66198
GPN2 GPN-loop GTPase 2 -1.64371
GHRHR growth hormone releasing hormone receptor -1.64263
LMNB2 lamin B2 -1.6396
C3ORF38 chromosome 3 open reading frame 38 -1.63865
IL7R interleukin 7 receptor -1.63496
USF2 upstream transcription factor 2, c-fos interacting -1.62823
EFNA1 ephrin-A1 -1.62667
ELP3 elongator acetyltransferase complex subunit 3 -1.62351
PC pyruvate carboxylase -1.62249
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.62055
NAGA N-acetylgalactosaminidase, alpha- -1.61911
CCL1 chemokine (C-C motif) ligand 1 -1.6167
NT5DC2 5'-nucleotidase domain containing 2 -1.61661
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -1.61481
MOB2 MOB kinase activator 2 -1.60908
GPR12 G protein-coupled receptor 12 -1.60239
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 -1.60051
NECAP1 NECAP endocytosis associated 1 -1.59689
LDHA lactate dehydrogenase A -1.59576
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.5949
TUSC2 tumor suppressor candidate 2 -1.59414
EIF3D eukaryotic translation initiation factor 3, subunit D -1.59318
BAAT bile acid CoA:amino acid N-acyltransferase -1.59298
MARK4 MAP/microtubule affinity-regulating kinase 4 -1.59201
UQCRB ubiquinol-cytochrome c reductase binding protein -1.59046
KIAA1161 KIAA1161 -1.59043
VIM vimentin -1.58961
DEAF1 DEAF1 transcription factor -1.5896
MGLL monoglyceride lipase -1.58856
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.58398
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.58209
SIPA1L2 signal-induced proliferation-associated 1 like 2 -1.57924
ZHX1 zinc fingers and homeoboxes 1 -1.57823
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.57576
IFT46 intraflagellar transport 46 -1.56703
GPR132 G protein-coupled receptor 132 -1.5643
C5AR1 complement component 5a receptor 1 -1.56391
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -1.56334
CBX2 chromobox homolog 2 -1.56036
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -1.55728
CKM creatine kinase, muscle -1.54704
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -1.54566
C2ORF49 chromosome 2 open reading frame 49 -1.54565
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa -1.54206
CNOT3 CCR4-NOT transcription complex, subunit 3 -1.53711
ACADL acyl-CoA dehydrogenase, long chain -1.53061
LSP1 lymphocyte-specific protein 1 -1.53054
CTNNBIP1 catenin, beta interacting protein 1 -1.53032
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -1.53016
PREPL prolyl endopeptidase-like -1.5293
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -1.52793
SRP54 signal recognition particle 54kDa -1.52099
TUBA4A tubulin, alpha 4a -1.51971
ACSM2A acyl-CoA synthetase medium-chain family member 2A -1.51508
SREBF1 sterol regulatory element binding transcription factor 1 -1.5132
IFT88 intraflagellar transport 88 -1.50695
TNNI3 troponin I type 3 (cardiac) -1.50427
BAIAP2 BAI1-associated protein 2 -1.50397
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -1.50021
CA14 carbonic anhydrase XIV -1.49922
SRCAP Snf2-related CREBBP activator protein -1.49784
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.49766
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 -1.49698
ARL4D ADP-ribosylation factor-like 4D -1.49204
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.49189
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.49069
ACO2 aconitase 2, mitochondrial -1.49034
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.48435
RNF141 ring finger protein 141 -1.48342
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -1.48289
MRAS muscle RAS oncogene homolog -1.4815
FABP5 fatty acid binding protein 5 (psoriasis-associated) -1.48081
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -1.47634
GRIA4 glutamate receptor, ionotropic, AMPA 4 -1.47412
PDLIM4 PDZ and LIM domain 4 -1.47087
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.46841
TARDBP TAR DNA binding protein -1.4679
SUCLG1 succinate-CoA ligase, alpha subunit -1.46759
FZD2 frizzled class receptor 2 -1.4641
ATAD3A ATPase family, AAA domain containing 3A -1.46327
CDK18 cyclin-dependent kinase 18 -1.46216
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.46021
CCDC63 coiled-coil domain containing 63 -1.45835
POT1 protection of telomeres 1 -1.45415
IL17RA interleukin 17 receptor A -1.45405
SEC14L2 SEC14-like 2 (S. cerevisiae) -1.45305
ERO1L ERO1-like (S. cerevisiae) -1.45242
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -1.44711
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -1.44635
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -1.44361
UPK3B uroplakin 3B -1.43989
OXCT1 3-oxoacid CoA transferase 1 -1.439
MDH1 malate dehydrogenase 1, NAD (soluble) -1.43736
LYST lysosomal trafficking regulator -1.43676
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -1.43516
ANKRD10 ankyrin repeat domain 10 -1.43344
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.43298
RDX radixin -1.42998
ANKRD11 ankyrin repeat domain 11 -1.42902
ULK2 unc-51 like autophagy activating kinase 2 -1.42862
LALBA lactalbumin, alpha- -1.42369
CUL1 cullin 1 -1.42196
HBE1 hemoglobin, epsilon 1 -1.42025
ATAD1 ATPase family, AAA domain containing 1 -1.41913
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.41631
NUDCD3 NudC domain containing 3 -1.41576
PRRC1 proline-rich coiled-coil 1 -1.41417
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -1.41096
TMEM37 transmembrane protein 37 -1.40861