Hypertension, Portal Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006975
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Genes

116 genes/proteins associated with the disease Hypertension, Portal from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
VEGFA vascular endothelial growth factor A 2.88009
AVP arginine vasopressin 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
TNF tumor necrosis factor 1.90292
NOS2 nitric oxide synthase 2, inducible 1.88042
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.87708
ALB albumin 1.81921
IL1B interleukin 1, beta 1.81885
IL6 interleukin 6 1.78797
MAPK3 mitogen-activated protein kinase 3 1.72426
MAPK1 mitogen-activated protein kinase 1 1.71586
CAT catalase 1.6593
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.65555
IL10 interleukin 10 1.59125
FAS Fas cell surface death receptor 1.58421
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.57971
IFNG interferon, gamma 1.56851
MPO myeloperoxidase 1.5673
BAX BCL2-associated X protein 1.56288
MMP9 matrix metallopeptidase 9 1.55673
TGFB1 transforming growth factor, beta 1 1.53917
NPPA natriuretic peptide A 1.52262
BCL2 B-cell CLL/lymphoma 2 1.51456
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.50423
TP53 tumor protein p53 1.48531
HMOX1 heme oxygenase 1 1.48454
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.46807
FOS FBJ murine osteosarcoma viral oncogene homolog 1.45115
IL4 interleukin 4 1.43809
MMP2 matrix metallopeptidase 2 1.43809
SOD1 superoxide dismutase 1, soluble 1.39086
ACTA2 actin, alpha 2, smooth muscle, aorta 1.36562
EDN1 endothelin 1 1.35357
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.35041
IGF1 insulin-like growth factor 1 (somatomedin C) 1.34694
CCL2 chemokine (C-C motif) ligand 2 1.34256
DDIT3 DNA-damage-inducible transcript 3 1.34024
EGFR epidermal growth factor receptor 1.32607
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.32132
IGFBP3 insulin-like growth factor binding protein 3 1.31
ADRB2 adrenoceptor beta 2, surface 1.31
SOD2 superoxide dismutase 2, mitochondrial 1.29225
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.28241
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.27966
BCL2L1 BCL2-like 1 1.27905
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.27009
FGF1 fibroblast growth factor 1 (acidic) 1.26576
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.26576
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.26514
ICAM1 intercellular adhesion molecule 1 1.26205
GSTM1 glutathione S-transferase mu 1 1.26021
DUSP1 dual specificity phosphatase 1 1.25557
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.25214
GCLC glutamate-cysteine ligase, catalytic subunit 1.25152
MGST1 microsomal glutathione S-transferase 1 1.2352
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.23233
COL3A1 collagen, type III, alpha 1 1.23201
PRL prolactin 1.22727
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.21759
PPARA peroxisome proliferator-activated receptor alpha 1.21695
ATF3 activating transcription factor 3 1.2137
FN1 fibronectin 1 1.2137
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.20558
CD14 CD14 molecule 1.2013
INS insulin 1.1977
GPX1 glutathione peroxidase 1 1.19574
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.19574
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.19246
CCND1 cyclin D1 1.18359
LEP leptin 1.17893
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.1786
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.165
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.14989
GSTP1 glutathione S-transferase pi 1 1.14989
SERINC3 serine incorporator 3 1.14541
INHBA inhibin, beta A 1.1437
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.13963
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.13827
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.13793
TLR4 toll-like receptor 4 1.13655
GJA1 gap junction protein, alpha 1, 43kDa 1.13415
XDH xanthine dehydrogenase 1.13177
FASLG Fas ligand (TNF superfamily, member 6) 1.12973
NFE2L2 nuclear factor, erythroid 2-like 2 1.12973
APP amyloid beta (A4) precursor protein 1.12599
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.12185
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.11809
IL1A interleukin 1, alpha 1.11255
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.11046
IL2 interleukin 2 1.10942
KRT18 keratin 18, type I 1.10033
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.09047
RNASE4 ribonuclease, RNase A family, 4 1.08407
ACACB acetyl-CoA carboxylase beta 1.08372
GCLM glutamate-cysteine ligase, modifier subunit 1.08301
IL1RN interleukin 1 receptor antagonist 1.07768
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.07482
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.07482
F3 coagulation factor III (thromboplastin, tissue factor) 1.06406
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.05793
SST somatostatin 1.05498
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.05349
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.05274
CPT1A carnitine palmitoyltransferase 1A (liver) 1.052
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.052
UBC ubiquitin C 1.05163
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.04684
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.04163
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.03939
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.03493
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.03345
REN renin 1.02447
MT1A metallothionein 1A 1.0204
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.01852
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.01663
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.01174