Hypersensitivity Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods. (Human Disease Ontology, DOID_1205)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006967
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Genes

570 genes/proteins associated with the disease Hypersensitivity from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.88009
CCL24 chemokine (C-C motif) ligand 24 2.88009
HP haptoglobin 2.88009
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.88009
IFNG interferon, gamma 2.88009
IL17A interleukin 17A 2.88009
OVAAL ovarian adenocarcinoma amplified long non-coding RNA 2.88009
SPON2 spondin 2, extracellular matrix protein 2.88009
MYLK myosin light chain kinase 2.88009
IL6ST interleukin 6 signal transducer 2.88009
IL2RB interleukin 2 receptor, beta 2.88009
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.88009
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 2.88009
CCL20 chemokine (C-C motif) ligand 20 2.88009
TNF tumor necrosis factor 2.88009
CCR2 chemokine (C-C motif) receptor 2 2.88009
IL1B interleukin 1, beta 2.88009
IL18 interleukin 18 2.88009
IL13 interleukin 13 2.88009
CCL11 chemokine (C-C motif) ligand 11 2.88009
CCL17 chemokine (C-C motif) ligand 17 2.88009
CCL19 chemokine (C-C motif) ligand 19 2.88009
TAC1 tachykinin, precursor 1 2.88009
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.88009
PF4 platelet factor 4 2.88009
CXCR3 chemokine (C-X-C motif) receptor 3 2.88009
CXCR2 chemokine (C-X-C motif) receptor 2 2.88009
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.88009
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.88009
SPP1 secreted phosphoprotein 1 2.88009
ALB albumin 2.88009
CD274 CD274 molecule 2.88009
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.88009
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.88009
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.88009
CCR6 chemokine (C-C motif) receptor 6 2.88009
DSG1 desmoglein 1 2.88009
IL6 interleukin 6 2.88009
IL4 interleukin 4 2.88009
CCR1 chemokine (C-C motif) receptor 1 2.88009
CCR9 chemokine (C-C motif) receptor 9 2.88009
IL1R2 interleukin 1 receptor, type II 2.88009
KNG1 kininogen 1 2.88009
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.88009
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.88009
CXCL5 chemokine (C-X-C motif) ligand 5 2.88009
CXCL9 chemokine (C-X-C motif) ligand 9 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
CCL2 chemokine (C-C motif) ligand 2 2.88009
CCL3 chemokine (C-C motif) ligand 3 2.88009
CCL7 chemokine (C-C motif) ligand 7 2.88009
CCL4 chemokine (C-C motif) ligand 4 2.88009
CCL8 chemokine (C-C motif) ligand 8 2.88009
IL5RA interleukin 5 receptor, alpha 2.88009
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.88009
CD40LG CD40 ligand 2.88009
IL1R1 interleukin 1 receptor, type I 2.88009
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.88009
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.88009
HLA-B major histocompatibility complex, class I, B 2.88009
CXCL8 chemokine (C-X-C motif) ligand 8 2.37651
IL10 interleukin 10 2.23372
IL2 interleukin 2 2.15517
ICAM1 intercellular adhesion molecule 1 2.12715
NOS2 nitric oxide synthase 2, inducible 2.10586
IL5 interleukin 5 2.09226
HRH1 histamine receptor H1 2.08368
CAT catalase 2.08236
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.05645
ATF3 activating transcription factor 3 2.01567
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.99975
IL1A interleukin 1, alpha 1.99047
MAPK1 mitogen-activated protein kinase 1 1.98525
MMP9 matrix metallopeptidase 9 1.97464
BCL2 B-cell CLL/lymphoma 2 1.97434
GSTP1 glutathione S-transferase pi 1 1.97185
IL12B interleukin 12B 1.96566
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.95285
FAS Fas cell surface death receptor 1.94469
CCL5 chemokine (C-C motif) ligand 5 1.93798
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.93659
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.93613
HMOX1 heme oxygenase 1 1.93231
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.91944
BAX BCL2-associated X protein 1.91384
JUN jun proto-oncogene 1.91317
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.90836
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.90804
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.8996
GSR glutathione reductase 1.87559
NQO1 NAD(P)H dehydrogenase, quinone 1 1.86305
GCLM glutamate-cysteine ligase, modifier subunit 1.86045
CXCL2 chemokine (C-X-C motif) ligand 2 1.85939
CXCR4 chemokine (C-X-C motif) receptor 4 1.84587
TP53 tumor protein p53 1.84287
HSPA1A heat shock 70kDa protein 1A 1.83095
SOD1 superoxide dismutase 1, soluble 1.82884
NGF nerve growth factor (beta polypeptide) 1.82639
VCAM1 vascular cell adhesion molecule 1 1.81337
SOD2 superoxide dismutase 2, mitochondrial 1.80057
TXNRD1 thioredoxin reductase 1 1.79618
MAPK3 mitogen-activated protein kinase 3 1.78568
FOS FBJ murine osteosarcoma viral oncogene homolog 1.78188
VEGFA vascular endothelial growth factor A 1.76013
ARG2 arginase 2 1.74882
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.74802
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.74661
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.74661
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.74321
SQSTM1 sequestosome 1 1.742
GSTM1 glutathione S-transferase mu 1 1.73557
NFE2L2 nuclear factor, erythroid 2-like 2 1.73353
IL7R interleukin 7 receptor 1.73211
CD86 CD86 molecule 1.73028
CTSL cathepsin L 1.72096
EGFR epidermal growth factor receptor 1.72055
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.71993
FN1 fibronectin 1 1.7185
GADD45A growth arrest and DNA-damage-inducible, alpha 1.7105
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.70678
PPARG peroxisome proliferator-activated receptor gamma 1.69555
GSTT1 glutathione S-transferase theta 1 1.69082
MPO myeloperoxidase 1.68825
COL1A1 collagen, type I, alpha 1 1.68718
CXCL10 chemokine (C-X-C motif) ligand 10 1.68633
HSPA8 heat shock 70kDa protein 8 1.67847
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.6649
FOSL1 FOS-like antigen 1 1.6649
TIMP1 TIMP metallopeptidase inhibitor 1 1.66102
GCLC glutamate-cysteine ligase, catalytic subunit 1.65643
BCL2L1 BCL2-like 1 1.65292
SRXN1 sulfiredoxin 1 1.64842
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.64348
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.63921
BDNF brain-derived neurotrophic factor 1.63116
HSPB1 heat shock 27kDa protein 1 1.61782
F3 coagulation factor III (thromboplastin, tissue factor) 1.6169
MMP1 matrix metallopeptidase 1 1.59802
C3 complement component 3 1.59731
MAPK9 mitogen-activated protein kinase 9 1.59708
NOS3 nitric oxide synthase 3 (endothelial cell) 1.58818
MMP2 matrix metallopeptidase 2 1.58607
CCND1 cyclin D1 1.57378
MAPK14 mitogen-activated protein kinase 14 1.56994
MAPK8 mitogen-activated protein kinase 8 1.5641
IL7 interleukin 7 1.55624
INHBA inhibin, beta A 1.5555
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1.55378
DUSP1 dual specificity phosphatase 1 1.5528
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.5501
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.54499
BIRC3 baculoviral IAP repeat containing 3 1.54281
SAA1 serum amyloid A1 1.54257
DDIT3 DNA-damage-inducible transcript 3 1.53772
CALCA calcitonin-related polypeptide alpha 1.53332
GSK3B glycogen synthase kinase 3 beta 1.52388
CTSB cathepsin B 1.52086
LCN2 lipocalin 2 1.52086
BID BH3 interacting domain death agonist 1.52061
MAPT microtubule-associated protein tau 1.5186
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.51205
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.50979
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.50801
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.50675
CD40 CD40 molecule, TNF receptor superfamily member 5 1.50675
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.50574
EGR1 early growth response 1 1.50398
RGS1 regulator of G-protein signaling 1 1.5012
STAT1 signal transducer and activator of transcription 1, 91kDa 1.49711
THBS1 thrombospondin 1 1.49407
S100A4 S100 calcium binding protein A4 1.49407
ADM adrenomedullin 1.49174
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.49045
CREM cAMP responsive element modulator 1.48787
HRAS Harvey rat sarcoma viral oncogene homolog 1.48659
CP ceruloplasmin (ferroxidase) 1.48505
TSC22D3 TSC22 domain family, member 3 1.48479
EDN1 endothelin 1 1.48402
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.4794
IFRD1 interferon-related developmental regulator 1 1.47582
NOX4 NADPH oxidase 4 1.47582
IER3 immediate early response 3 1.47452
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.47244
CREB1 cAMP responsive element binding protein 1 1.46807
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.46727
SLFN12L schlafen family member 12-like 1.46251
MT2A metallothionein 2A 1.4612
CCL22 chemokine (C-C motif) ligand 22 1.46015
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.45936
GPX3 glutathione peroxidase 3 1.45803
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.45643
GSTA1 glutathione S-transferase alpha 1 1.45484
ACTA2 actin, alpha 2, smooth muscle, aorta 1.44001
GPNMB glycoprotein (transmembrane) nmb 1.44001
IRF1 interferon regulatory factor 1 1.43591
IL12A interleukin 12A 1.43293
CTGF connective tissue growth factor 1.42696
CD36 CD36 molecule (thrombospondin receptor) 1.42156
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.41938
MFGE8 milk fat globule-EGF factor 8 protein 1.41856
PLAT plasminogen activator, tissue 1.41802
GDF15 growth differentiation factor 15 1.41802
G6PD glucose-6-phosphate dehydrogenase 1.4164
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.41586
FABP3 fatty acid binding protein 3, muscle and heart 1.41285
TLR4 toll-like receptor 4 1.41285
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41202
TIMP2 TIMP metallopeptidase inhibitor 2 1.40925
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.40705
MMP3 matrix metallopeptidase 3 1.40705
CTSD cathepsin D 1.40513
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.39813
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.39813
MCL1 myeloid cell leukemia 1 1.39674
TGFA transforming growth factor, alpha 1.38918
CCNB1 cyclin B1 1.38891
PLAU plasminogen activator, urokinase 1.38641
TLR2 toll-like receptor 2 1.38412
BECN1 beclin 1, autophagy related 1.38412
FTH1 ferritin, heavy polypeptide 1 1.38412
GADD45B growth arrest and DNA-damage-inducible, beta 1.38412
KLF4 Kruppel-like factor 4 (gut) 1.38412
TXN thioredoxin 1.3793
CYR61 cysteine-rich, angiogenic inducer, 61 1.37446
CSF3 colony stimulating factor 3 (granulocyte) 1.37189
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.36791
COL18A1 collagen, type XVIII, alpha 1 1.36562
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.36161
POR P450 (cytochrome) oxidoreductase 1.36133
CD8A CD8a molecule 1.36047
IL1RN interleukin 1 receptor antagonist 1.36019
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.36019
HSPA1B heat shock 70kDa protein 1B 1.35792
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.35792
PCNA proliferating cell nuclear antigen 1.35763
PARP1 poly (ADP-ribose) polymerase 1 1.35647
BAK1 BCL2-antagonist/killer 1 1.3556
STIP1 stress-induced phosphoprotein 1 1.35069
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.35041
GSTA3 glutathione S-transferase alpha 3 1.34926
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.34897
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.34694
SGK1 serum/glucocorticoid regulated kinase 1 1.34401
NUPR1 nuclear protein, transcriptional regulator, 1 1.34401
MAP2K1 mitogen-activated protein kinase kinase 1 1.34169
SPHK1 sphingosine kinase 1 1.33966
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.3388
CAPN2 calpain 2, (m/II) large subunit 1.33612
PLAUR plasminogen activator, urokinase receptor 1.33523
E2F1 E2F transcription factor 1 1.33523
EGR2 early growth response 2 1.33199
IL11 interleukin 11 1.32905
GSTM3 glutathione S-transferase mu 3 (brain) 1.32846
S100A9 S100 calcium binding protein A9 1.32667
PRNP prion protein 1.32667
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.32667
NINJ1 ninjurin 1 1.32637
CCR7 chemokine (C-C motif) receptor 7 1.32637
IL1RL1 interleukin 1 receptor-like 1 1.32547
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.32428
ACTB actin, beta 1.32428
BAD BCL2-associated agonist of cell death 1.32339
APOE apolipoprotein E 1.31985
CD44 CD44 molecule (Indian blood group) 1.31566
DDIT4 DNA-damage-inducible transcript 4 1.31327
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.31327
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.31267
MMP12 matrix metallopeptidase 12 1.31208
FGF2 fibroblast growth factor 2 (basic) 1.31089
FASLG Fas ligand (TNF superfamily, member 6) 1.30911
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.30881
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.30819
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.30819
TFRC transferrin receptor 1.30574
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.30512
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.30269
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.30026
SFTPA1 surfactant protein A1 1.29812
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.29688
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.29657
GPX1 glutathione peroxidase 1 1.29194
AIF1L allograft inflammatory factor 1-like 1.2898
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.28641
UBE2B ubiquitin-conjugating enzyme E2B 1.2861
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.2821
CYCS cytochrome c, somatic 1.28119
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.28088
FABP1 fatty acid binding protein 1, liver 1.27997
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.27751
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.27751
TH tyrosine hydroxylase 1.27657
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.27626
CD80 CD80 molecule 1.27626
IL15 interleukin 15 1.27378
AR androgen receptor 1.27255
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.27039
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.26917
CSF2RBP1 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) pseudogene 1 1.26856
DUSP4 dual specificity phosphatase 4 1.26576
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.26421
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 1.26329
MGST1 microsomal glutathione S-transferase 1 1.26329
ESR1 estrogen receptor 1 1.26329
CANX calnexin 1.26205
B2M beta-2-microglobulin 1.26113
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.25868
COL3A1 collagen, type III, alpha 1 1.25868
NAMPT nicotinamide phosphoribosyltransferase 1.25838
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.25776
GSTM2 glutathione S-transferase mu 2 (muscle) 1.25494
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.25432
ISG15 ISG15 ubiquitin-like modifier 1.25028
EEF2 eukaryotic translation elongation factor 2 1.24966
USPL1 ubiquitin specific peptidase like 1 1.2475
CCNA2 cyclin A2 1.2475
STAT5B signal transducer and activator of transcription 5B 1.24718
SELL selectin L 1.24655
GSTA2 glutathione S-transferase alpha 2 1.24433
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.24401
SRGN serglycin 1.24181
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.24118
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.2368
CXCL3 chemokine (C-X-C motif) ligand 3 1.23552
JUNB jun B proto-oncogene 1.23265
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.23169
AKR1C2 aldo-keto reductase family 1, member C2 1.23137
SOD3 superoxide dismutase 3, extracellular 1.22979
MUC16 mucin 16, cell surface associated 1.22821
BCL6 B-cell CLL/lymphoma 6 1.22821
H2AFX H2A histone family, member X 1.22727
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.22664
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.22469
CD83 CD83 molecule 1.22469
SQLE squalene epoxidase 1.22436
ATF4 activating transcription factor 4 1.22274
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.22177
GJA1 gap junction protein, alpha 1, 43kDa 1.21823
OSM oncostatin M 1.21727
CLU clusterin 1.21468
TF transferrin 1.21402
AK2 adenylate kinase 2 1.21206
ATG5 autophagy related 5 1.21206
FOSL2 FOS-like antigen 2 1.21043
TFEC transcription factor EC 1.21011
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.21011
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.20816
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.20751
CXCL11 chemokine (C-X-C motif) ligand 11 1.20719
BCLAF1 BCL2-associated transcription factor 1 1.20719
COL4A1 collagen, type IV, alpha 1 1.20361
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.20295
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.20295
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.20295
CALR calreticulin 1.20031
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.199
LMCD1 LIM and cysteine-rich domains 1 1.19802
HSPH1 heat shock 105kDa/110kDa protein 1 1.1977
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.1977
ARG1 arginase 1 1.1977
PHGDH phosphoglycerate dehydrogenase 1.19704
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.19704
CDK1 cyclin-dependent kinase 1 1.19639
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.19509
CLIC4 chloride intracellular channel 4 1.19345
MT3 metallothionein 3 1.19014
TIMP3 TIMP metallopeptidase inhibitor 3 1.19014
S100A8 S100 calcium binding protein A8 1.19014
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.18882
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.18685
ACHE acetylcholinesterase (Yt blood group) 1.18652
APAF1 apoptotic peptidase activating factor 1 1.18489
CDC20 cell division cycle 20 1.18489
IL4R interleukin 4 receptor 1.18456
ADRM1 adhesion regulating molecule 1 1.18293
BBC3 BCL2 binding component 3 1.18259
F2 coagulation factor II (thrombin) 1.18093
SFTPB surfactant protein B 1.17993
IL3 interleukin 3 1.17563
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.17101
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.16799
BIRC2 baculoviral IAP repeat containing 2 1.16799
GHR growth hormone receptor 1.16799
HSF1 heat shock transcription factor 1 1.16799
TGFB3 transforming growth factor, beta 3 1.16799
PRDX1 peroxiredoxin 1 1.16799
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.16567
F13A1 coagulation factor XIII, A1 polypeptide 1.16434
CFLAR CASP8 and FADD-like apoptosis regulator 1.16302
SLPI secretory leukocyte peptidase inhibitor 1.16302
THY1 Thy-1 cell surface antigen 1.16302
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.16137
COMT catechol-O-methyltransferase 1.16137
IRS1 insulin receptor substrate 1 1.1607
ANGPTL4 angiopoietin-like 4 1.1607
RRM2 ribonucleotide reductase M2 1.1607
PDE4B phosphodiesterase 4B, cAMP-specific 1.15865
FGB fibrinogen beta chain 1.15865
BIRC5 baculoviral IAP repeat containing 5 1.15729
CCNB2 cyclin B2 1.15593
CCND3 cyclin D3 1.15593
ANXA1 annexin A1 1.15593
BTG1 B-cell translocation gene 1, anti-proliferative 1.1556
PLIN2 perilipin 2 1.1529
SAA2 serum amyloid A2 1.15256
UBD ubiquitin D 1.15089
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.14678
INSIG1 insulin induced gene 1 1.14678
PTGR1 prostaglandin reductase 1 1.1437
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.14268
DUT deoxyuridine triphosphatase 1.14268
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 1.14098
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.14098
PRDX6 peroxiredoxin 6 1.14098
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.13997
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.13895
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.13895
DPYD dihydropyrimidine dehydrogenase 1.13793
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.13793
NDRG1 N-myc downstream regulated 1 1.13758
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.13518
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.13518
RGS16 regulator of G-protein signaling 16 1.13518
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.13518
CDK2 cyclin-dependent kinase 2 1.13484
AREG amphiregulin 1.13313
GPX4 glutathione peroxidase 4 1.13245
HSPE1 heat shock 10kDa protein 1 1.13211
ZFP36 ZFP36 ring finger protein 1.13211
DICER1 dicer 1, ribonuclease type III 1.12973
MMP13 matrix metallopeptidase 13 1.12872
PPARA peroxisome proliferator-activated receptor alpha 1.12838
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.12426
HMGB1 high mobility group box 1 1.12391
TYMP thymidine phosphorylase 1.12357
CTSK cathepsin K 1.12014
LTA lymphotoxin alpha 1.12014
FKBP4 FK506 binding protein 4, 59kDa 1.12014
CH25H cholesterol 25-hydroxylase 1.11911
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.11911
AQP3 aquaporin 3 (Gill blood group) 1.11843
PGD phosphogluconate dehydrogenase 1.11843
PBK PDZ binding kinase 1.11639
BTG2 BTG family, member 2 1.11571
LITAF lipopolysaccharide-induced TNF factor 1.11255
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.11255
RB1 retinoblastoma 1 1.1122
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.10942
CAV1 caveolin 1, caveolae protein, 22kDa 1.10734
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 1.10631
CTSC cathepsin C 1.10562
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.10562
PRDX2 peroxiredoxin 2 1.10493
CFB complement factor B 1.10211
LOX lysyl oxidase 1.10211
GADD45G growth arrest and DNA-damage-inducible, gamma 1.10211
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.09857
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 1.09857
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.09506
FYN FYN proto-oncogene, Src family tyrosine kinase 1.09506
NTF3 neurotrophin 3 1.09506
AKR1C3 aldo-keto reductase family 1, member C3 1.09471
JUND jun D proto-oncogene 1.09436
RTP4 receptor (chemosensory) transporter protein 4 1.09366
COPE coatomer protein complex, subunit epsilon 1.09366
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.09366
UGDH UDP-glucose 6-dehydrogenase 1.09154
ODC1 ornithine decarboxylase 1 1.09011
HBEGF heparin-binding EGF-like growth factor 1.08904
TXNRD2 thioredoxin reductase 2 1.08868
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.08868
CD68 CD68 molecule 1.08797
CXCL12 chemokine (C-X-C motif) ligand 12 1.08655
USP18 ubiquitin specific peptidase 18 1.08407
SAA3P serum amyloid A3 pseudogene 1.08407
PRKCD protein kinase C, delta 1.08266
AHR aryl hydrocarbon receptor 1.08196
OGG1 8-oxoguanine DNA glycosylase 1.07911
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.07911
IRS2 insulin receptor substrate 2 1.07804
LEP leptin 1.07732
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.0766
NFIL3 nuclear factor, interleukin 3 regulated 1.07482
SAT1 spermidine/spermine N1-acetyltransferase 1 1.07482
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.07269
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.07163
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.07163
ATG12 autophagy related 12 1.07163
GSTA4 glutathione S-transferase alpha 4 1.07057
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.06844
NCF2 neutrophil cytosolic factor 2 1.06808
CSF1 colony stimulating factor 1 (macrophage) 1.06808
ANXA2 annexin A2 1.06661
BAG3 BCL2-associated athanogene 3 1.06515
PSAT1 phosphoserine aminotransferase 1 1.06479
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.06479
MT1A metallothionein 1A 1.06297
DCN decorin 1.06188
CYBB cytochrome b-245, beta polypeptide 1.06152
TRADD TNFRSF1A-associated via death domain 1.06116
ADRB2 adrenoceptor beta 2, surface 1.059
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.059
FST follistatin 1.05864
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.05864
SHISA2 shisa family member 2 1.05793
NPPB natriuretic peptide B 1.05461
FADD Fas (TNFRSF6)-associated via death domain 1.05237
HPX hemopexin 1.052
TBX21 T-box 21 1.05089
FGG fibrinogen gamma chain 1.04904
ELN elastin 1.04757
ANGPT1 angiopoietin 1 1.04757
OSMR oncostatin M receptor 1.04757
BDKRB1 bradykinin receptor B1 1.04757
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.04611
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.04611
TNC tenascin C 1.04611
IL12RB1 interleukin 12 receptor, beta 1 1.04427
RAB32 RAB32, member RAS oncogene family 1.04427
NME7 NME/NM23 family member 7 1.04427
FFAR2 free fatty acid receptor 2 1.04314
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.04239
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.04088
FBXO9 F-box protein 9 1.03789
FAM46A family with sequence similarity 46, member A 1.03752
EPAS1 endothelial PAS domain protein 1 1.03678
CD47 CD47 molecule 1.03493
AXL AXL receptor tyrosine kinase 1.03493
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.03493
CRP C-reactive protein, pentraxin-related 1.03456
PRICKLE1 prickle homolog 1 (Drosophila) 1.03159
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.03159
BMP6 bone morphogenetic protein 6 1.03084
ACTC1 actin, alpha, cardiac muscle 1 1.03084
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.03084
BCL3 B-cell CLL/lymphoma 3 1.03084
CHEK2 checkpoint kinase 2 1.03084
BHLHE40 basic helix-loop-helix family, member e40 1.03084
GSN gelsolin 1.03084
TGFB2 transforming growth factor, beta 2 1.02858
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.02783
AMPD3 adenosine monophosphate deaminase 3 1.02671
HSPA1L heat shock 70kDa protein 1-like 1.02671
IL24 interleukin 24 1.02671
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.02671
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.02634
MACF1 microtubule-actin crosslinking factor 1 1.02522
LHFP lipoma HMGIC fusion partner 1.02522
MAOA monoamine oxidase A 1.0241
ACACB acetyl-CoA carboxylase beta 1.02262
LYN LYN proto-oncogene, Src family tyrosine kinase 1.02262
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.02262
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.02188
PKNOX2 PBX/knotted 1 homeobox 2 1.02114
THBS4 thrombospondin 4 1.01928
PIGR polymeric immunoglobulin receptor 1.01928
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.0189
ATF5 activating transcription factor 5 1.01852
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.01852
ENO3 enolase 3 (beta, muscle) 1.01852
PTEN phosphatase and tensin homolog 1.01625
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.01549
NR1D2 nuclear receptor subfamily 1, group D, member 2 1.01474
FABP7 fatty acid binding protein 7, brain 1.01474
FDPS farnesyl diphosphate synthase 1.01324
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.01324
SYN2 synapsin II 1.01324
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.01062
IL3RA interleukin 3 receptor, alpha (low affinity) 1.01062
AURKA aurora kinase A 1.01062
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.01062