Hypersensitivity, Immediate Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

173 genes associated with the Hypersensitivity, Immediate phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAM23 ADAM metallopeptidase domain 23
ADAM33 ADAM metallopeptidase domain 33
ADAMTSL1 ADAMTS-like 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADRB2 adrenoceptor beta 2, surface
AICDA activation-induced cytidine deaminase
ALOX5 arachidonate 5-lipoxygenase
ARG1 arginase 1
ARG2 arginase 2
BDNF brain-derived neurotrophic factor
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5 complement component 5
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD28 CD28 molecule
CDH26 cadherin 26
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIA chitinase, acidic
CHIT1 chitinase 1 (chitotriosidase)
CHRM3 cholinergic receptor, muscarinic 3
COL18A1 collagen, type XVIII, alpha 1
COL6A5 collagen, type VI, alpha 5
CRHR1 corticotropin releasing hormone receptor 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DEFB1 defensin, beta 1
DPP10 dipeptidyl-peptidase 10 (non-functional)
EDN1 endothelin 1
EDNRA endothelin receptor type A
ESR1 estrogen receptor 1
FADS1 fatty acid desaturase 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GSDMA gasdermin A
GSDMB gasdermin B
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HNMT histamine N-methyltransferase
HPGDS hematopoietic prostaglandin D synthase
HRH3 histamine receptor H3
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL15 interleukin 15
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITK IL2-inducible T-cell kinase
KDR kinase insert domain receptor
LACTB lactamase, beta
LTA lymphotoxin alpha
LTC4S leukotriene C4 synthase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MINA MYC induced nuclear antigen
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MPO myeloperoxidase
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC7 mucin 7, secreted
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPSR1 neuropeptide S receptor 1
NRIP2 nuclear receptor interacting protein 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PHF11 PHD finger protein 11
PKDCC protein kinase domain containing, cytoplasmic
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD50 RAD50 homolog (S. cerevisiae)
RORA RAR-related orphan receptor A
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB3A2 secretoglobin, family 3A, member 2
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SPINK5 serine peptidase inhibitor, Kazal type 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX21 T-box 21
TBXA2R thromboxane A2 receptor
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TSLP thymic stromal lymphopoietin
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIMP VCP-interacting membrane selenoprotein