Hyperphagia Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A neurological anomaly with gross overeating associated with an abnormally strong desire or need to eat. (Human Phenotype Ontology, HP_0002591)
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Genes

14 genes associated with the Hyperphagia phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ANKK1 ankyrin repeat and kinase domain containing 1
BDNF brain-derived neurotrophic factor
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
FTO fat mass and obesity associated
KSR2 kinase suppressor of ras 2
LEPR leptin receptor
MC4R melanocortin 4 receptor
MCHR1 melanin-concentrating hormone receptor 1
OPRM1 opioid receptor, mu 1
SIM1 single-minded family bHLH transcription factor 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TAS2R38 taste receptor, type 2, member 38
TPH2 tryptophan hydroxylase 2