|Dataset||CTD Gene-Chemical Interactions|
|Description||A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 188.8.131.52 for the NADPH-dependent enzyme and EC 184.108.40.206 for an NADH-dependent enzyme. (Chemical Entities of Biological Interest Ontology, CHEBI_35664)|
|Downloads & Tools|
4 genes/proteins interacting with the chemical Hydroxymethylglutaryl-CoA Reductase Inhibitors from the curated CTD Gene-Chemical Interactions dataset.