Hydroxymethylglutaryl-CoA Reductase Inhibitors Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme. (Chemical Entities of Biological Interest Ontology, CHEBI_35664)
External Link http://ctdbase.org/detail.go?type=chem&acc=D019161
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Genes

4 genes/proteins interacting with the chemical Hydroxymethylglutaryl-CoA Reductase Inhibitors from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
APOE apolipoprotein E
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled