Huntington Disease Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A neurodegenerative disease and an autosomal dominant disease that is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities. (Human Disease Ontology, DOID_12858)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006816
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Genes

21 genes/proteins associated with the disease Huntington Disease from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CNR1 cannabinoid receptor 1 (brain) 2.88009
RCAN1 regulator of calcineurin 1 2.88009
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.88009
HTT huntingtin 2.88009
OGG1 8-oxoguanine DNA glycosylase 2.88009
GDNF glial cell derived neurotrophic factor 2.88009
FAAH fatty acid amide hydrolase 2.88009
DIABLO diablo, IAP-binding mitochondrial protein 2.88009
STK11 serine/threonine kinase 11 2.88009
IP6K2 inositol hexakisphosphate kinase 2 2.88009
BDNF brain-derived neurotrophic factor 1.33257
BCL2 B-cell CLL/lymphoma 2 1.22242
CAT catalase 1.17431
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.13484
APP amyloid beta (A4) precursor protein 1.12599
TNF tumor necrosis factor 1.09047
DRD2 dopamine receptor D2 1.08196
DRD1 dopamine receptor D1 1.07482
GSK3B glycogen synthase kinase 3 beta 1.04352
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.02971
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.02671