Huntington's Disease_CNS - Brain - Cerebellum (MMHCC)_GSE3248 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3248
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Genes

600 genes differentially expressed during Huntington's Disease_CNS - Brain - Cerebellum (MMHCC)_GSE3248 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
HBS1L HBS1-like translational GTPase 3.47461
SFXN4 sideroflexin 4 3.45038
PIAS1 protein inhibitor of activated STAT, 1 2.9562
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 2.94127
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2.92016
AKIRIN2 akirin 2 2.73652
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2.7001
RPL21 ribosomal protein L21 2.69994
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.69528
WDR81 WD repeat domain 81 2.69406
EIF3C eukaryotic translation initiation factor 3, subunit C 2.63465
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.60893
CNOT1 CCR4-NOT transcription complex, subunit 1 2.5994
PCBP2 poly(rC) binding protein 2 2.57804
SON SON DNA binding protein 2.56653
SUN1 Sad1 and UNC84 domain containing 1 2.56597
ING4 inhibitor of growth family, member 4 2.55767
PGRMC1 progesterone receptor membrane component 1 2.54725
ILF3 interleukin enhancer binding factor 3, 90kDa 2.53037
TRIM27 tripartite motif containing 27 2.52336
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.52143
ARL14EP ADP-ribosylation factor-like 14 effector protein 2.51737
ZIC3 Zic family member 3 2.4963
ANAPC5 anaphase promoting complex subunit 5 2.46715
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 2.4604
RBM42 RNA binding motif protein 42 2.45627
TMED2 transmembrane emp24 domain trafficking protein 2 2.44657
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.4385
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.43436
WNK1 WNK lysine deficient protein kinase 1 2.42105
NPEPPS aminopeptidase puromycin sensitive 2.41759
NECAP1 NECAP endocytosis associated 1 2.41265
PEG3 paternally expressed 3 2.40079
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.38966
SNX17 sorting nexin 17 2.38789
RBM18 RNA binding motif protein 18 2.38126
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.36509
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.36102
PUM2 pumilio RNA-binding family member 2 2.35466
CMIP c-Maf inducing protein 2.33239
DAZAP2 DAZ associated protein 2 2.31457
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.31366
RIN2 Ras and Rab interactor 2 2.30196
ECH1 enoyl CoA hydratase 1, peroxisomal 2.29202
MBTD1 mbt domain containing 1 2.29072
PLD3 phospholipase D family, member 3 2.27557
IL6ST interleukin 6 signal transducer 2.26102
COPB1 coatomer protein complex, subunit beta 1 2.25946
C6ORF62 chromosome 6 open reading frame 62 2.25637
CINP cyclin-dependent kinase 2 interacting protein 2.23516
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.233
EXOC7 exocyst complex component 7 2.22693
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 2.22632
CCT4 chaperonin containing TCP1, subunit 4 (delta) 2.22568
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.21237
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2.20392
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.19876
TNRC6A trinucleotide repeat containing 6A 2.19382
EVL Enah/Vasp-like 2.17983
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.16824
TMED7 transmembrane emp24 protein transport domain containing 7 2.166
EPC1 enhancer of polycomb homolog 1 (Drosophila) 2.16424
PSAT1 phosphoserine aminotransferase 1 2.16276
GSTZ1 glutathione S-transferase zeta 1 2.15454
RPL6 ribosomal protein L6 2.15176
ZC3H11A zinc finger CCCH-type containing 11A 2.15016
UBE2B ubiquitin-conjugating enzyme E2B 2.14517
BAD BCL2-associated agonist of cell death 2.12882
IMP3 IMP3, U3 small nucleolar ribonucleoprotein 2.11539
ELP2 elongator acetyltransferase complex subunit 2 2.11368
NEK6 NIMA-related kinase 6 2.11302
DPYSL4 dihydropyrimidinase-like 4 2.09572
NDN necdin, melanoma antigen (MAGE) family member 2.09083
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.0897
FN1 fibronectin 1 2.08443
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 2.08217
SNX9 sorting nexin 9 2.08184
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.07381
SNX1 sorting nexin 1 2.07233
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.06641
FLCN folliculin 2.06157
MTA2 metastasis associated 1 family, member 2 2.05038
NUB1 negative regulator of ubiquitin-like proteins 1 2.04903
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 2.04846
TMEM176B transmembrane protein 176B 2.04408
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.03981
TMEM126A transmembrane protein 126A 2.03311
CHMP7 charged multivesicular body protein 7 2.03039
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.02774
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.0118
GPI glucose-6-phosphate isomerase 2.00928
SOD2 superoxide dismutase 2, mitochondrial 2.00791
SRRT serrate, RNA effector molecule 1.99457
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.98727
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.98576
FAM32A family with sequence similarity 32, member A 1.97999
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.97784
ZFR2 zinc finger RNA binding protein 2 1.96994
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.96286
NTF3 neurotrophin 3 1.96278
PPID peptidylprolyl isomerase D 1.96193
MAPT microtubule-associated protein tau 1.95264
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.95203
CALB2 calbindin 2 1.94527
JAK1 Janus kinase 1 1.94306
FAM8A1 family with sequence similarity 8, member A1 1.93807
WDR7 WD repeat domain 7 1.93189
CAPN5 calpain 5 1.92753
SOX4 SRY (sex determining region Y)-box 4 1.92746
GLG1 golgi glycoprotein 1 1.92641
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.92098
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 1.9163
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.91459
TUBB tubulin, beta class I 1.9127
DUSP8 dual specificity phosphatase 8 1.91259
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.90966
BAG6 BCL2-associated athanogene 6 1.90591
PCDHB11 protocadherin beta 11 1.90506
ROGDI rogdi homolog (Drosophila) 1.90374
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 1.89848
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 1.89768
HMGN1 high mobility group nucleosome binding domain 1 1.89683
BEX4 brain expressed, X-linked 4 1.89501
ALCAM activated leukocyte cell adhesion molecule 1.88237
FLOT1 flotillin 1 1.88201
IFT172 intraflagellar transport 172 1.88129
MOB1A MOB kinase activator 1A 1.8791
CUL2 cullin 2 1.87573
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.87329
ACP2 acid phosphatase 2, lysosomal 1.85865
DSTN destrin (actin depolymerizing factor) 1.85564
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.85355
CHMP3 charged multivesicular body protein 3 1.85063
PABPC1 poly(A) binding protein, cytoplasmic 1 1.84977
TCF4 transcription factor 4 1.849
ITM2C integral membrane protein 2C 1.84729
FBXW4 F-box and WD repeat domain containing 4 1.84253
ATXN2 ataxin 2 1.83799
MYT1 myelin transcription factor 1 1.83639
NRIP1 nuclear receptor interacting protein 1 1.83311
LMF1 lipase maturation factor 1 1.83172
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.81913
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.81819
C11ORF73 chromosome 11 open reading frame 73 1.80998
ANAPC1 anaphase promoting complex subunit 1 1.80461
KDM3B lysine (K)-specific demethylase 3B 1.79511
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like 1.79394
PHYH phytanoyl-CoA 2-hydroxylase 1.78855
ERGIC3 ERGIC and golgi 3 1.78439
CBX5 chromobox homolog 5 1.77649
RAD21 RAD21 homolog (S. pombe) 1.77562
WDR26 WD repeat domain 26 1.77152
EBF1 early B-cell factor 1 1.77
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 1.76062
TMEM131 transmembrane protein 131 1.75816
RAB7A RAB7A, member RAS oncogene family 1.75578
CYBA cytochrome b-245, alpha polypeptide 1.75251
SFXN1 sideroflexin 1 1.75138
IMPAD1 inositol monophosphatase domain containing 1 1.74871
MECP2 methyl CpG binding protein 2 1.74612
LASP1 LIM and SH3 protein 1 1.74012
TMEM222 transmembrane protein 222 1.73396
RFK riboflavin kinase 1.73194
ADD1 adducin 1 (alpha) 1.73188
RPIA ribose 5-phosphate isomerase A 1.73092
ZFR zinc finger RNA binding protein 1.73077
MXI1 MAX interactor 1, dimerization protein 1.7302
RPL7A ribosomal protein L7a 1.72713
RPL37A ribosomal protein L37a 1.72442
TRAK1 trafficking protein, kinesin binding 1 1.72392
ASF1A anti-silencing function 1A histone chaperone 1.72335
NPC1 Niemann-Pick disease, type C1 1.72252
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.71692
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.71535
MRPS14 mitochondrial ribosomal protein S14 1.71483
POU3F3 POU class 3 homeobox 3 1.71149
RTN3 reticulon 3 1.70826
SIVA1 SIVA1, apoptosis-inducing factor 1.70804
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.70549
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 1.69958
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.69946
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.69341
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.68641
RRP1B ribosomal RNA processing 1B 1.68583
RNF167 ring finger protein 167 1.68121
C11ORF49 chromosome 11 open reading frame 49 1.68047
PTPRF protein tyrosine phosphatase, receptor type, F 1.67867
PDPK1 3-phosphoinositide dependent protein kinase 1 1.67811
TMEM165 transmembrane protein 165 1.6739
CLTC clathrin, heavy chain (Hc) 1.67056
ANXA5 annexin A5 1.66985
RPL7 ribosomal protein L7 1.66516
MED23 mediator complex subunit 23 1.6605
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.65641
RPL5 ribosomal protein L5 1.65151
SQSTM1 sequestosome 1 1.64394
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 1.63585
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.63508
PWP1 PWP1 homolog (S. cerevisiae) 1.63342
CLCN3 chloride channel, voltage-sensitive 3 1.63005
ZNF639 zinc finger protein 639 1.63004
NCKAP1 NCK-associated protein 1 1.62898
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.62881
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.6269
CGGBP1 CGG triplet repeat binding protein 1 1.62554
ZC3H14 zinc finger CCCH-type containing 14 1.62292
CELF4 CUGBP, Elav-like family member 4 1.62263
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.61599
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.61577
CAPRIN2 caprin family member 2 1.61506
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.61392
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 1.61378
SLC4A3 solute carrier family 4 (anion exchanger), member 3 1.60874
NANS N-acetylneuraminic acid synthase 1.60871
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1.60774
RPS26 ribosomal protein S26 1.60605
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.60497
LRRC59 leucine rich repeat containing 59 1.60433
ATF4 activating transcription factor 4 1.60351
EMD emerin 1.60198
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.60152
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.60013
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.59853
PARP8 poly (ADP-ribose) polymerase family, member 8 1.59309
SBF2 SET binding factor 2 1.58863
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.58741
NAV2 neuron navigator 2 1.58715
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.58655
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.58647
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 1.58357
TBRG1 transforming growth factor beta regulator 1 1.58169
TENM2 teneurin transmembrane protein 2 1.58125
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.58039
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.57899
CTNND2 catenin (cadherin-associated protein), delta 2 1.57736
PDS5B PDS5 cohesin associated factor B 1.57579
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.57325
RPL8 ribosomal protein L8 1.57213
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 1.57198
ZNF274 zinc finger protein 274 1.57031
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 1.57026
ATXN7L3 ataxin 7-like 3 1.56687
UBE3A ubiquitin protein ligase E3A 1.56504
SNAPIN SNAP-associated protein 1.56408
CIDEA cell death-inducing DFFA-like effector a 1.56359
CTSV cathepsin V 1.56302
FAM103A1 family with sequence similarity 103, member A1 1.5622
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 1.56045
MFN1 mitofusin 1 1.55928
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.55467
KIAA2013 KIAA2013 1.55269
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 1.55174
ITPK1 inositol-tetrakisphosphate 1-kinase 1.54776
COPA coatomer protein complex, subunit alpha 1.54711
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.54478
GSK3A glycogen synthase kinase 3 alpha 1.54425
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.54307
LARP1 La ribonucleoprotein domain family, member 1 1.54302
SP1 Sp1 transcription factor 1.54301
DCAF11 DDB1 and CUL4 associated factor 11 1.54245
RAB8A RAB8A, member RAS oncogene family 1.54072
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.53962
UBE2R2 ubiquitin-conjugating enzyme E2R 2 1.53858
EI24 etoposide induced 2.4 1.5367
GNAS GNAS complex locus 1.53541
RSL24D1 ribosomal L24 domain containing 1 1.53455
CTSD cathepsin D 1.53448
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.5337
HNF1A HNF1 homeobox A 1.53311
MAN1B1 mannosidase, alpha, class 1B, member 1 1.53211
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1.52781
WDR92 WD repeat domain 92 1.52736
EVI2A ecotropic viral integration site 2A 1.52689
MAU2 MAU2 sister chromatid cohesion factor 1.52643
MED1 mediator complex subunit 1 1.5259
TBL2 transducin (beta)-like 2 1.52478
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.52121
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 1.51663
CXXC1 CXXC finger protein 1 1.51572
RNF14 ring finger protein 14 1.51058
CTBP2 C-terminal binding protein 2 1.50965
TESK1 testis-specific kinase 1 1.50607
KLF7 Kruppel-like factor 7 (ubiquitous) 1.50369
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 1.5034
SAP18 Sin3A-associated protein, 18kDa 1.50038
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.49966
RPL10 ribosomal protein L10 1.4994
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 1.49569
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.49381
NFYC nuclear transcription factor Y, gamma 1.4884
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.48749
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 1.48299
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1.48169
PXK PX domain containing serine/threonine kinase 1.47849
ADRA2C adrenoceptor alpha 2C 1.4749
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.46925
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 1.46835
CPEB2 cytoplasmic polyadenylation element binding protein 2 1.46667
ZFPM2 zinc finger protein, FOG family member 2 1.4664
C12ORF57 chromosome 12 open reading frame 57 1.46589

decreased expression

Symbol Name Standardized Value
C20ORF24 chromosome 20 open reading frame 24 -3.27665
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.26283
RBMS1 RNA binding motif, single stranded interacting protein 1 -3.12934
FGF1 fibroblast growth factor 1 (acidic) -3.07166
CSTB cystatin B (stefin B) -3.0375
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -2.97796
DIAPH1 diaphanous-related formin 1 -2.91014
PRKCD protein kinase C, delta -2.78512
CCNDBP1 cyclin D-type binding-protein 1 -2.74456
OXCT1 3-oxoacid CoA transferase 1 -2.72422
CDKN2AIPNL CDKN2A interacting protein N-terminal like -2.7144
PKM pyruvate kinase, muscle -2.70626
TMEM199 transmembrane protein 199 -2.66208
NMT1 N-myristoyltransferase 1 -2.65826
EN2 engrailed homeobox 2 -2.64997
FUCA1 fucosidase, alpha-L- 1, tissue -2.57481
KCTD17 potassium channel tetramerization domain containing 17 -2.5546
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.54588
TSSC4 tumor suppressing subtransferable candidate 4 -2.54348
PFKL phosphofructokinase, liver -2.51957
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.51932
DCTN3 dynactin 3 (p22) -2.50176
MCM3AP minichromosome maintenance complex component 3 associated protein -2.48377
GUK1 guanylate kinase 1 -2.48354
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.46684
CANT1 calcium activated nucleotidase 1 -2.43187
YIPF1 Yip1 domain family, member 1 -2.40261
OLFM2 olfactomedin 2 -2.40197
IFRD2 interferon-related developmental regulator 2 -2.35323
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.34582
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -2.3161
IL4R interleukin 4 receptor -2.30419
NCAPH2 non-SMC condensin II complex, subunit H2 -2.30288
ARNTL aryl hydrocarbon receptor nuclear translocator-like -2.28012
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.27558
TP53INP1 tumor protein p53 inducible nuclear protein 1 -2.27193
LMO2 LIM domain only 2 (rhombotin-like 1) -2.2679
KIAA0930 KIAA0930 -2.26311
DDA1 DET1 and DDB1 associated 1 -2.23901
DGCR2 DiGeorge syndrome critical region gene 2 -2.21197
MTIF2 mitochondrial translational initiation factor 2 -2.19646
ARID4B AT rich interactive domain 4B (RBP1-like) -2.17906
ETV1 ets variant 1 -2.1757
KAT2B K(lysine) acetyltransferase 2B -2.1703
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -2.16852
CYB5R4 cytochrome b5 reductase 4 -2.1666
SCN1B sodium channel, voltage gated, type I beta subunit -2.16422
JPH3 junctophilin 3 -2.16052
HES6 hes family bHLH transcription factor 6 -2.15535
LENG9 leukocyte receptor cluster (LRC) member 9 -2.14232
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -2.12408
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.1192
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -2.11475
PSD pleckstrin and Sec7 domain containing -2.11429
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.10513
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.10201
INPP5F inositol polyphosphate-5-phosphatase F -2.09657
UROS uroporphyrinogen III synthase -2.09541
DCTN6 dynactin 6 -2.07657
WNT3 wingless-type MMTV integration site family, member 3 -2.07171
CSNK1D casein kinase 1, delta -2.05199
HAGH hydroxyacylglutathione hydrolase -2.04626
FAM134A family with sequence similarity 134, member A -2.04423
TMEM229B transmembrane protein 229B -2.03886
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.03761
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 -2.03113
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.02521
MRPL16 mitochondrial ribosomal protein L16 -2.02503
GRPEL2 GrpE-like 2, mitochondrial (E. coli) -2.01729
CA2 carbonic anhydrase II -2.01026
ADAM11 ADAM metallopeptidase domain 11 -1.98862
STMN3 stathmin-like 3 -1.98415
INPP5K inositol polyphosphate-5-phosphatase K -1.98054
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -1.97942
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.97386
VMP1 vacuole membrane protein 1 -1.97022
C20ORF27 chromosome 20 open reading frame 27 -1.96561
FABP3 fatty acid binding protein 3, muscle and heart -1.96428
INPP5J inositol polyphosphate-5-phosphatase J -1.96356
WIZ widely interspaced zinc finger motifs -1.95232
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.95212
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.95056
ERCC2 excision repair cross-complementation group 2 -1.94708
CISD1 CDGSH iron sulfur domain 1 -1.94328
NDRG2 NDRG family member 2 -1.94298
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -1.9392
CDK16 cyclin-dependent kinase 16 -1.93882
PALM paralemmin -1.92586
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -1.92003
RAD23A RAD23 homolog A (S. cerevisiae) -1.91959
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -1.9187
CRTAM cytotoxic and regulatory T cell molecule -1.91674
AK4 adenylate kinase 4 -1.91614
CBLN1 cerebellin 1 precursor -1.90903
ARL4C ADP-ribosylation factor-like 4C -1.90161
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.90101
DHCR24 24-dehydrocholesterol reductase -1.89156
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.88672
TRAK2 trafficking protein, kinesin binding 2 -1.88462
PFDN2 prefoldin subunit 2 -1.88129
CLDND1 claudin domain containing 1 -1.87941
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.87882
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.87544
DRG1 developmentally regulated GTP binding protein 1 -1.87349
PRDX2 peroxiredoxin 2 -1.86055
GRM8 glutamate receptor, metabotropic 8 -1.85361
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.85159
LGI4 leucine-rich repeat LGI family, member 4 -1.84847
GHITM growth hormone inducible transmembrane protein -1.84845
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -1.84582
MYBPC3 myosin binding protein C, cardiac -1.84397
D2HGDH D-2-hydroxyglutarate dehydrogenase -1.8399
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -1.83421
PEX11B peroxisomal biogenesis factor 11 beta -1.82783
THY1 Thy-1 cell surface antigen -1.82631
PTCH1 patched 1 -1.82597
DESI1 desumoylating isopeptidase 1 -1.82325
SEPT11 septin 11 -1.8216
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -1.80773
HDGFRP2 hepatoma-derived growth factor-related protein 2 -1.80148
TSC2 tuberous sclerosis 2 -1.79887
LTK leukocyte receptor tyrosine kinase -1.79467
FAM101B family with sequence similarity 101, member B -1.7889
HLA-A major histocompatibility complex, class I, A -1.78099
FGFR2 fibroblast growth factor receptor 2 -1.7623
C1R complement component 1, r subcomponent -1.76214
ZDHHC14 zinc finger, DHHC-type containing 14 -1.76065
BCL6 B-cell CLL/lymphoma 6 -1.75761
VSNL1 visinin-like 1 -1.75302
CCDC28B coiled-coil domain containing 28B -1.75178
TMEM123 transmembrane protein 123 -1.75026
HAT1 histone acetyltransferase 1 -1.73842
HARS histidyl-tRNA synthetase -1.73688
KLF10 Kruppel-like factor 10 -1.7356
STRN3 striatin, calmodulin binding protein 3 -1.73452
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -1.73218
TPST1 tyrosylprotein sulfotransferase 1 -1.72889
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -1.72685
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -1.724
HP haptoglobin -1.7231
CCDC63 coiled-coil domain containing 63 -1.72271
HDLBP high density lipoprotein binding protein -1.72217
PI4K2A phosphatidylinositol 4-kinase type 2 alpha -1.71766
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.71551
MRPS21 mitochondrial ribosomal protein S21 -1.71476
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.70161
ZNHIT1 zinc finger, HIT-type containing 1 -1.7006
SUSD6 sushi domain containing 6 -1.70054
C6ORF106 chromosome 6 open reading frame 106 -1.69781
UBQLN1 ubiquilin 1 -1.69502
PVALB parvalbumin -1.69015
LONP2 lon peptidase 2, peroxisomal -1.68952
TMEM147 transmembrane protein 147 -1.6885
FAAH fatty acid amide hydrolase -1.68783
P3H3 prolyl 3-hydroxylase 3 -1.68351
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -1.67991
ANKRD17 ankyrin repeat domain 17 -1.67967
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -1.67495
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -1.67169
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.67044
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -1.6701
ERP29 endoplasmic reticulum protein 29 -1.66303
CDC42SE1 CDC42 small effector 1 -1.65717
POLB polymerase (DNA directed), beta -1.65534
TMEM38B transmembrane protein 38B -1.65303
SCG2 secretogranin II -1.65278
UBE2K ubiquitin-conjugating enzyme E2K -1.65134
FADS1 fatty acid desaturase 1 -1.65067
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -1.64975
COL5A1 collagen, type V, alpha 1 -1.64919
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -1.64376
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 -1.64277
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.63708
CECR6 cat eye syndrome chromosome region, candidate 6 -1.63696
EIF6 eukaryotic translation initiation factor 6 -1.63696
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.63559
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.6338
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -1.63296
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.63214
PDCD6 programmed cell death 6 -1.63089
NKAIN1 Na+/K+ transporting ATPase interacting 1 -1.62837
SMS spermine synthase -1.62739
RAP1GAP RAP1 GTPase activating protein -1.62457
NSG1 neuron specific gene family member 1 -1.62338
CENPBD1 CENPB DNA-binding domains containing 1 -1.62318
TTC1 tetratricopeptide repeat domain 1 -1.62292
SEPT7 septin 7 -1.6222
CLTB clathrin, light chain B -1.62082
MRPL24 mitochondrial ribosomal protein L24 -1.6202
MACROD2 MACRO domain containing 2 -1.61628
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -1.61376
CREB3L1 cAMP responsive element binding protein 3-like 1 -1.61318
GIPC2 GIPC PDZ domain containing family, member 2 -1.61313
DDT D-dopachrome tautomerase -1.60514
BTBD3 BTB (POZ) domain containing 3 -1.6043
FAM49B family with sequence similarity 49, member B -1.6018
LYPLA2 lysophospholipase II -1.6015
BMP1 bone morphogenetic protein 1 -1.60134
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -1.59837
PAQR7 progestin and adipoQ receptor family member VII -1.59743
GDF10 growth differentiation factor 10 -1.59492
PARK7 parkinson protein 7 -1.58636
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -1.58534
PARD6A par-6 family cell polarity regulator alpha -1.58426
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.57997
RTN4 reticulon 4 -1.57973
HBEGF heparin-binding EGF-like growth factor -1.57852
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.57548
AMY2A amylase, alpha 2A (pancreatic) -1.57545
KLC1 kinesin light chain 1 -1.57301
COX17 COX17 cytochrome c oxidase copper chaperone -1.57177
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.57145
TRAFD1 TRAF-type zinc finger domain containing 1 -1.57024
NUCB1 nucleobindin 1 -1.56908
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -1.56872
CFP complement factor properdin -1.56522
GRIK1 glutamate receptor, ionotropic, kainate 1 -1.56455
ITFG1 integrin alpha FG-GAP repeat containing 1 -1.56148
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -1.55637
ANXA6 annexin A6 -1.55594
HPCAL1 hippocalcin-like 1 -1.55348
HIST1H2BI histone cluster 1, H2bi -1.55255
DAO D-amino-acid oxidase -1.55239
GRB2 growth factor receptor-bound protein 2 -1.54807
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.54475
MAL mal, T-cell differentiation protein -1.54362
ADGRB1 adhesion G protein-coupled receptor B1 -1.54225
PNKD paroxysmal nonkinesigenic dyskinesia -1.54225
DOC2B double C2-like domains, beta -1.5422
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -1.54211
MYEOV2 myeloma overexpressed 2 -1.54165
EFHD2 EF-hand domain family, member D2 -1.5406
CBX6 chromobox homolog 6 -1.54
ORC4 origin recognition complex, subunit 4 -1.53122
TRAPPC1 trafficking protein particle complex 1 -1.53106
ELOVL5 ELOVL fatty acid elongase 5 -1.53083
KLC2 kinesin light chain 2 -1.5254
CA4 carbonic anhydrase IV -1.5252
NEK2 NIMA-related kinase 2 -1.52457
KIF1A kinesin family member 1A -1.52419
INTS5 integrator complex subunit 5 -1.52305
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.51951
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -1.51872
SCN8A sodium channel, voltage gated, type VIII alpha subunit -1.51839
RASL11B RAS-like, family 11, member B -1.5167
ADAM23 ADAM metallopeptidase domain 23 -1.51174
PCBP4 poly(rC) binding protein 4 -1.51154
NRSN1 neurensin 1 -1.51068
PITPNA phosphatidylinositol transfer protein, alpha -1.50732
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -1.50705
ACSS1 acyl-CoA synthetase short-chain family member 1 -1.50643
RREB1 ras responsive element binding protein 1 -1.50548
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -1.50493
FAM107B family with sequence similarity 107, member B -1.50427
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -1.50344
GLYATL1 glycine-N-acyltransferase-like 1 -1.5008
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -1.49815
HDAC5 histone deacetylase 5 -1.49791
SESN1 sestrin 1 -1.49479
FDX1 ferredoxin 1 -1.49406
ZNF771 zinc finger protein 771 -1.49383
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -1.49219
LAMB3 laminin, beta 3 -1.48984
MCM4 minichromosome maintenance complex component 4 -1.48942
RER1 retention in endoplasmic reticulum sorting receptor 1 -1.48588
AKAP1 A kinase (PRKA) anchor protein 1 -1.48227
SKI SKI proto-oncogene -1.47874
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -1.4747
NHP2 NHP2 ribonucleoprotein -1.47425
ZRANB1 zinc finger, RAN-binding domain containing 1 -1.47326
EIF5 eukaryotic translation initiation factor 5 -1.47188
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -1.46766
SH2B3 SH2B adaptor protein 3 -1.46112
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -1.46051
ACR acrosin -1.45848
THOC3 THO complex 3 -1.45716
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.45562
MRPL43 mitochondrial ribosomal protein L43 -1.45161
SFPQ splicing factor proline/glutamine-rich -1.45157
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.45113
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -1.44898
UTS2R urotensin 2 receptor -1.44897
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -1.44887
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -1.44798
SLC35E4 solute carrier family 35, member E4 -1.4472
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -1.44667
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -1.44235
CDK8 cyclin-dependent kinase 8 -1.44198
HPCA hippocalcin -1.44081
SCOC short coiled-coil protein -1.44051
MCEE methylmalonyl CoA epimerase -1.43878
THRSP thyroid hormone responsive -1.43712
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.43593
PQLC1 PQ loop repeat containing 1 -1.4351
FGFR3 fibroblast growth factor receptor 3 -1.43045
UBXN8 UBX domain protein 8 -1.43001
NDRG4 NDRG family member 4 -1.42742
SDHAF2 succinate dehydrogenase complex assembly factor 2 -1.42427
XPO1 exportin 1 -1.42299
TBC1D22A TBC1 domain family, member 22A -1.42244