Homocysteine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain. (Chemical Entities of Biological Interest Ontology, CHEBI_17230)
External Link http://ctdbase.org/detail.go?type=chem&acc=D006710
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Genes

80 genes/proteins interacting with the chemical Homocysteine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACTA2 actin, alpha 2, smooth muscle, aorta
AHCY adenosylhomocysteinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CDH3 cadherin 3, type 1, P-cadherin (placental)
COMT catechol-O-methyltransferase
COX5B cytochrome c oxidase subunit Vb
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
DES desmin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EDN1 endothelin 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ERN1 endoplasmic reticulum to nucleus signaling 1
ERO1L ERO1-like (S. cerevisiae)
EXOSC4 exosome component 4
GH1 growth hormone 1
GPX1 glutathione peroxidase 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSR glutathione reductase
GSTM3 glutathione S-transferase mu 3 (brain)
HIST3H3 histone cluster 3, H3
HIST4H4 histone cluster 4, H4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
KEAP1 kelch-like ECH-associated protein 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MECP2 methyl CpG binding protein 2
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NCF1 neutrophil cytosolic factor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRC3 NLR family, CARD domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NT5E 5'-nucleotidase, ecto (CD73)
PON1 paraoxonase 1
PRDX6 peroxiredoxin 6
PYCARD PYD and CARD domain containing
RAB1B RAB1B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A4 S100 calcium binding protein A4
SLC46A1 solute carrier family 46 (folate transporter), member 1
SOD1 superoxide dismutase 1, soluble
SSR4 signal sequence receptor, delta
TIMP1 TIMP metallopeptidase inhibitor 1
TJP1 tight junction protein 1
TP53 tumor protein p53
VBP1 von Hippel-Lindau binding protein 1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
XBP1 X-box binding protein 1