Holoprosencephaly Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies. (Human Disease Ontology, DOID_4621)
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6 genes associated with the Holoprosencephaly phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APOB apolipoprotein B
APOE apolipoprotein E
GLI2 GLI family zinc finger 2
SHH sonic hedgehog
SIX3 SIX homeobox 3
TWSG1 twisted gastrulation BMP signaling modulator 1