Hodgkin Disease Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A lymphoma that is marked by the presence of a type of cell called the Reed-Sternberg cell. (Human Disease Ontology, DOID_8567)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006689
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Genes

71 genes/proteins associated with the disease Hodgkin Disease from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.88009
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.88009
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 2.88009
PVT1 Pvt1 oncogene (non-protein coding) 2.88009
IFNA2 interferon, alpha 2 2.88009
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.88009
GSTP1 glutathione S-transferase pi 1 2.88009
CFLAR CASP8 and FADD-like apoptosis regulator 2.88009
KLHDC8B kelch domain containing 8B 2.88009
GATA3 GATA binding protein 3 2.88009
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.88009
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.70512
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.65113
ERBB2 erb-b2 receptor tyrosine kinase 2 1.61506
GSTM1 glutathione S-transferase mu 1 1.54232
MGMT O-6-methylguanine-DNA methyltransferase 1.50624
BCL2 B-cell CLL/lymphoma 2 1.42156
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.41257
PRC1 protein regulator of cytokinesis 1 1.35647
TP53 tumor protein p53 1.33761
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.33672
THBS1 thrombospondin 1 1.33169
FSHB follicle stimulating hormone, beta polypeptide 1.32876
BAX BCL2-associated X protein 1.31956
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.27875
IL6 interleukin 6 1.27224
S100P S100 calcium binding protein P 1.26329
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.25807
TGFB1 transforming growth factor, beta 1 1.25276
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.22884
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.2013
PARP1 poly (ADP-ribose) polymerase 1 1.19933
H2AFX H2A histone family, member X 1.19509
TOP2A topoisomerase (DNA) II alpha 170kDa 1.19509
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.18751
FASLG Fas ligand (TNF superfamily, member 6) 1.18226
GPX3 glutathione peroxidase 3 1.17431
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.16866
CAT catalase 1.15492
IL1B interleukin 1, beta 1.14541
TNF tumor necrosis factor 1.12973
BCL2L1 BCL2-like 1 1.12426
CDK2 cyclin-dependent kinase 2 1.12151
FAS Fas cell surface death receptor 1.11707
TFPI2 tissue factor pathway inhibitor 2 1.10699
ALAD aminolevulinate dehydratase 1.10424
AXL AXL receptor tyrosine kinase 1.10353
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.10175
CTGF connective tissue growth factor 1.0766
IFNG interferon, gamma 1.07234
TIMP1 TIMP metallopeptidase inhibitor 1 1.06952
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.05864
BIRC2 baculoviral IAP repeat containing 2 1.05498
RRM2 ribonucleotide reductase M2 1.04904
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.04721
FYN FYN proto-oncogene, Src family tyrosine kinase 1.04126
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.04126
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.03901
CHEK2 checkpoint kinase 2 1.03789
BAK1 BCL2-antagonist/killer 1 1.03419
HSPA2 heat shock 70kDa protein 2 1.03271
VCAM1 vascular cell adhesion molecule 1 1.03235
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.03197
LHB luteinizing hormone beta polypeptide 1.02373
F3 coagulation factor III (thromboplastin, tissue factor) 1.02151
FANCG Fanconi anemia, complementation group G 1.01776
VEGFA vascular endothelial growth factor A 1.01549
JUN jun proto-oncogene 1.01512
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.01324
RUNX3 runt-related transcription factor 3 1.01324