Hepatitis B, Chronic Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

201 genes associated with the Hepatitis B, Chronic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAR adenosine deaminase, RNA-specific
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
AR androgen receptor
ATF6 activating transcription factor 6
AXIN1 axin 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDIT3 DNA-damage-inducible transcript 3
DEPDC5 DEP domain containing 5
DRD4 dopamine receptor D4
EDN1 endothelin 1
EGF epidermal growth factor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FDX1 ferredoxin 1
FOXP1 forkhead box P1
FURIN furin (paired basic amino acid cleaving enzyme)
GNLY granulysin
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAVCR2 hepatitis A virus cellular receptor 2
HDAC10 histone deacetylase 10
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HULC hepatocellular carcinoma up-regulated long non-coding RNA
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA5 interferon, alpha 5
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNL2 interferon, lambda 2
IFNL3 interferon, lambda 3
IFNL4 interferon, lambda 4 (gene/pseudogene)
IFNLR1 interferon, lambda receptor 1
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL12A interleukin 12A
IL12B interleukin 12B
IL16 interleukin 16
IL17A interleukin 17A
IL18 interleukin 18
IL19 interleukin 19
IL1B interleukin 1, beta
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL21R interleukin 21 receptor
IL23R interleukin 23 receptor
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF8 interferon regulatory factor 8
IRF9 interferon regulatory factor 9
ITGAV integrin, alpha V
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KIF1B kinesin family member 1B
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LEPR leptin receptor
LTA lymphotoxin alpha
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MIR218-2 microRNA 218-2
MIR499A microRNA 499a
MLH1 mutL homolog 1
MMP3 matrix metallopeptidase 3
MTTP microsomal triglyceride transfer protein
MX1 MX dynamin-like GTPase 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NXF3 nuclear RNA export factor 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OGG1 8-oxoguanine DNA glycosylase
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDCD1 programmed cell death 1
PGD phosphogluconate dehydrogenase
PGF placental growth factor
PNPLA3 patatin-like phospholipase domain containing 3
POT1 protection of telomeres 1
PTEN phosphatase and tensin homolog
RAB40AL RAB40A, member RAS oncogene family-like
RNASEK ribonuclease, RNase K
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SPP1 secreted phosphoprotein 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
TANK TRAF family member-associated NFKB activator
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF19 transcription factor 19
TEP1 telomerase-associated protein 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE4B ubiquitination factor E4B
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XBP1 X-box binding protein 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB12 zinc finger and BTB domain containing 12