Hepatic Veno-Occlusive Disease Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006504
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Genes

218 genes/proteins associated with the disease Hepatic Veno-Occlusive Disease from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
OCLN occludin 2.88009
TP53 tumor protein p53 2.13103
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.1231
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.06112
BCL2L1 BCL2-like 1 2.04137
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.03509
IL6 interleukin 6 1.98582
BCL2 B-cell CLL/lymphoma 2 1.97799
PARP1 poly (ADP-ribose) polymerase 1 1.95117
F3 coagulation factor III (thromboplastin, tissue factor) 1.925
BAX BCL2-associated X protein 1.90242
VEGFA vascular endothelial growth factor A 1.89927
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.8965
TNF tumor necrosis factor 1.8854
VCAM1 vascular cell adhesion molecule 1 1.87725
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.85957
TYMS thymidylate synthetase 1.80096
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.79732
H2AFX H2A histone family, member X 1.76462
SOD2 superoxide dismutase 2, mitochondrial 1.74661
TGFB1 transforming growth factor, beta 1 1.70678
CDK2 cyclin-dependent kinase 2 1.70077
IGFBP3 insulin-like growth factor binding protein 3 1.69972
IL1B interleukin 1, beta 1.69825
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.69297
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.68633
GSTP1 glutathione S-transferase pi 1 1.67675
FASLG Fas ligand (TNF superfamily, member 6) 1.6582
ERBB2 erb-b2 receptor tyrosine kinase 2 1.64326
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.63832
HMOX1 heme oxygenase 1 1.63116
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.62153
GSTM1 glutathione S-transferase mu 1 1.61107
PRC1 protein regulator of cytokinesis 1 1.59731
JUN jun proto-oncogene 1.59195
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.58584
BIRC5 baculoviral IAP repeat containing 5 1.55108
MCL1 myeloid cell leukemia 1 1.55059
CAT catalase 1.54427
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.53012
CD44 CD44 molecule (Indian blood group) 1.51835
CXCL8 chemokine (C-X-C motif) ligand 8 1.51657
PCNA proliferating cell nuclear antigen 1.50549
EGR1 early growth response 1 1.49686
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.45643
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.44982
NOS2 nitric oxide synthase 2, inducible 1.4479
BIRC2 baculoviral IAP repeat containing 2 1.44735
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.43946
FOS FBJ murine osteosarcoma viral oncogene homolog 1.43864
GADD45A growth arrest and DNA-damage-inducible, alpha 1.43782
MAPK3 mitogen-activated protein kinase 3 1.43591
CCL2 chemokine (C-C motif) ligand 2 1.43103
MAPK1 mitogen-activated protein kinase 1 1.42642
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.42616
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.42616
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.42589
RB1 retinoblastoma 1 1.41424
MGMT O-6-methylguanine-DNA methyltransferase 1.40815
CCND1 cyclin D1 1.40204
PRKCD protein kinase C, delta 1.38355
MPO myeloperoxidase 1.37189
IGF1 insulin-like growth factor 1 (somatomedin C) 1.37018
TFPI2 tissue factor pathway inhibitor 2 1.36677
CTSL cathepsin L 1.36591
DDIT3 DNA-damage-inducible transcript 3 1.36304
CDK1 cyclin-dependent kinase 1 1.36218
BIRC3 baculoviral IAP repeat containing 3 1.36161
KLF6 Kruppel-like factor 6 1.3556
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.35357
NOS3 nitric oxide synthase 3 (endothelial cell) 1.3484
IL4 interleukin 4 1.34664
NQO1 NAD(P)H dehydrogenase, quinone 1 1.34518
LAMC2 laminin, gamma 2 1.3414
TOP2A topoisomerase (DNA) II alpha 170kDa 1.33464
THBS1 thrombospondin 1 1.32876
TYMP thymidine phosphorylase 1.32667
VIM vimentin 1.32547
NPPB natriuretic peptide B 1.31956
RRM2 ribonucleotide reductase M2 1.31237
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.30696
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.30329
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.29103
CCNE1 cyclin E1 1.28765
E2F1 E2F transcription factor 1 1.28333
PMP22 peripheral myelin protein 22 1.28333
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.28241
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.28149
LCN2 lipocalin 2 1.28027
ICAM1 intercellular adhesion molecule 1 1.27966
BTG2 BTG family, member 2 1.27845
FAS Fas cell surface death receptor 1.27751
IFNG interferon, gamma 1.26545
TRIM2 tripartite motif containing 2 1.26113
S100A4 S100 calcium binding protein A4 1.2596
TP53I3 tumor protein p53 inducible protein 3 1.25713
CXCL12 chemokine (C-X-C motif) ligand 12 1.25713
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.25713
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.25369
F2 coagulation factor II (thrombin) 1.24687
AURKA aurora kinase A 1.23962
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.23328
SRM spermidine synthase 1.2279
ALAD aminolevulinate dehydratase 1.22306
TIMP1 TIMP metallopeptidase inhibitor 1 1.22016
MAPK8 mitogen-activated protein kinase 8 1.21855
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.21695
IGFBP5 insulin-like growth factor binding protein 5 1.21501
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.21435
MMP1 matrix metallopeptidase 1 1.21206
AXL AXL receptor tyrosine kinase 1.20784
IL18 interleukin 18 1.20558
PTEN phosphatase and tensin homolog 1.20558
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.2046
BAD BCL2-associated agonist of cell death 1.20427
PDGFB platelet-derived growth factor beta polypeptide 1.2013
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.20031
STAT1 signal transducer and activator of transcription 1, 91kDa 1.199
TIMP3 TIMP metallopeptidase inhibitor 3 1.19379
MUCL1 mucin-like 1 1.19379
RAD51 RAD51 recombinase 1.19379
FHL1 four and a half LIM domains 1 1.18915
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.18554
SDC1 syndecan 1 1.18026
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.17728
IL10 interleukin 10 1.17695
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.17399
CCND3 cyclin D3 1.169
CXCL10 chemokine (C-X-C motif) ligand 10 1.16401
CHEK2 checkpoint kinase 2 1.16203
EDNRB endothelin receptor type B 1.16203
IL1A interleukin 1, alpha 1.15492
EGF epidermal growth factor 1.1529
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.15256
CCNA2 cyclin A2 1.15055
TXNRD1 thioredoxin reductase 1 1.14268
CHEK1 checkpoint kinase 1 1.13929
THBD thrombomodulin 1.13724
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.13518
C3 complement component 3 1.13313
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.13143
CSF1 colony stimulating factor 1 (macrophage) 1.13007
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.12838
MSH2 mutS homolog 2 1.12771
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.12564
DCN decorin 1.1253
FOSL1 FOS-like antigen 1 1.12254
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.12254
AR androgen receptor 1.11877
EGFR epidermal growth factor receptor 1.11707
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.1136
EMP2 epithelial membrane protein 2 1.1129
FOXO1 forkhead box O1 1.09998
MT2A metallothionein 2A 1.09822
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.09436
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.09366
NRP1 neuropilin 1 1.09154
SRGN serglycin 1.08904
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.08726
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.08231
NGF nerve growth factor (beta polypeptide) 1.07947
PRLR prolactin receptor 1.07911
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.0784
ALAS1 5'-aminolevulinate synthase 1 1.07696
CDKN2A cyclin-dependent kinase inhibitor 2A 1.07553
FKBP5 FK506 binding protein 5 1.07518
SORT1 sortilin 1 1.07093
PLAT plasminogen activator, tissue 1.06808
TUBA4A tubulin, alpha 4a 1.06771
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.06552
ACKR3 atypical chemokine receptor 3 1.06406
CCNB1 cyclin B1 1.0637
S100A9 S100 calcium binding protein A9 1.06116
PRNP prion protein 1.06116
PPARD peroxisome proliferator-activated receptor delta 1.05757
PROCR protein C receptor, endothelial 1.05721
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.05386
KYNU kynureninase 1.05349
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.05163
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.05052
CYCS cytochrome c, somatic 1.04794
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.04794
HMGA2 high mobility group AT-hook 2 1.04721
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.04611
OSBPL10 oxysterol binding protein-like 10 1.04538
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.04427
POSTN periostin, osteoblast specific factor 1.04427
C1QA complement component 1, q subcomponent, A chain 1.04389
S100P S100 calcium binding protein P 1.04389
GAMT guanidinoacetate N-methyltransferase 1.04051
DUSP10 dual specificity phosphatase 10 1.04051
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.04051
EPO erythropoietin 1.03901
BBC3 BCL2 binding component 3 1.03715
ANXA2 annexin A2 1.03715
NFE2L2 nuclear factor, erythroid 2-like 2 1.03678
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.0353
RFC3 replication factor C (activator 1) 3, 38kDa 1.03456
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.03382
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.03271
GSTA1 glutathione S-transferase alpha 1 1.03159
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.02821
CCNG1 cyclin G1 1.02821
IL2 interleukin 2 1.02522
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.02485
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.02262
IRS1 insulin receptor substrate 1 1.02151
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.02114
KRT8 keratin 8, type II 1.01966
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.01966
EDN1 endothelin 1 1.01966
BID BH3 interacting domain death agonist 1.0189
CCNB2 cyclin B2 1.01814
VCAN versican 1.01663
DUSP4 dual specificity phosphatase 4 1.01361
BUB3 BUB3 mitotic checkpoint protein 1.01212
RGS16 regulator of G-protein signaling 16 1.01099