Hepatic Cirrhosis_Hepatic Tissue_GSE1843 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1843
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Genes

600 genes differentially expressed during Hepatic Cirrhosis_Hepatic Tissue_GSE1843 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
BTF3 basic transcription factor 3 4.83926
YIPF5 Yip1 domain family, member 5 4.81687
RPS5 ribosomal protein S5 4.01769
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 3.82612
SRSF1 serine/arginine-rich splicing factor 1 3.53095
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 3.17426
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like 3.16361
PGAM1 phosphoglycerate mutase 1 (brain) 3.149
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 3.14153
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 3.11421
TBRG1 transforming growth factor beta regulator 1 3.07258
CREBZF CREB/ATF bZIP transcription factor 2.99366
SNX3 sorting nexin 3 2.96858
NANS N-acetylneuraminic acid synthase 2.96168
OLA1 Obg-like ATPase 1 2.94905
RPL31 ribosomal protein L31 2.80115
PHB prohibitin 2.71518
CDK4 cyclin-dependent kinase 4 2.67732
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.64982
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.61398
FKBP3 FK506 binding protein 3, 25kDa 2.61013
ABLIM3 actin binding LIM protein family, member 3 2.5944
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 2.58806
AK1 adenylate kinase 1 2.56375
EXOSC5 exosome component 5 2.51392
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.49964
PMEPA1 prostate transmembrane protein, androgen induced 1 2.36547
SSR1 signal sequence receptor, alpha 2.36537
RPS4Y1 ribosomal protein S4, Y-linked 1 2.35152
SCFD1 sec1 family domain containing 1 2.34559
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.28973
RPS27A ribosomal protein S27a 2.28467
MRPL55 mitochondrial ribosomal protein L55 2.28268
IFT20 intraflagellar transport 20 2.27598
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.25979
RAB2A RAB2A, member RAS oncogene family 2.2352
NME2 NME/NM23 nucleoside diphosphate kinase 2 2.20182
HMGN1 high mobility group nucleosome binding domain 1 2.19032
RPP25 ribonuclease P/MRP 25kDa subunit 2.16404
RPLP0 ribosomal protein, large, P0 2.09876
RPL6 ribosomal protein L6 2.07204
APRT adenine phosphoribosyltransferase 2.05791
PDLIM2 PDZ and LIM domain 2 (mystique) 2.05359
RPL15 ribosomal protein L15 2.04199
MRPL32 mitochondrial ribosomal protein L32 2.03402
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.03003
LSAMP limbic system-associated membrane protein 2.02272
RPL7A ribosomal protein L7a 2.01209
MT-ND3 NADH dehydrogenase, subunit 3 (complex I) 2.00343
LIN37 lin-37 DREAM MuvB core complex component 1.99419
VDAC2 voltage-dependent anion channel 2 1.98381
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.97045
PDCD5 programmed cell death 5 1.95936
PCBP2 poly(rC) binding protein 2 1.95328
PLIN3 perilipin 3 1.95071
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.94974
CCDC17 coiled-coil domain containing 17 1.94034
PRDX2 peroxiredoxin 2 1.93663
STOML2 stomatin (EPB72)-like 2 1.9351
ARL2BP ADP-ribosylation factor-like 2 binding protein 1.89607
FAM120A family with sequence similarity 120A 1.89317
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 1.89027
SRM spermidine synthase 1.8692
KANK1 KN motif and ankyrin repeat domains 1 1.8684
DYNLRB1 dynein, light chain, roadblock-type 1 1.86601
PTS 6-pyruvoyltetrahydropterin synthase 1.85664
RPL5 ribosomal protein L5 1.84984
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.8462
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.83564
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.82088
UFM1 ubiquitin-fold modifier 1 1.81811
TXNRD1 thioredoxin reductase 1 1.7933
AATF apoptosis antagonizing transcription factor 1.76754
PAWR PRKC, apoptosis, WT1, regulator 1.76364
GLO1 glyoxalase I 1.74756
TFAM transcription factor A, mitochondrial 1.74198
C11ORF73 chromosome 11 open reading frame 73 1.72614
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.72476
RPL19 ribosomal protein L19 1.72118
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.72014
RPS10 ribosomal protein S10 1.71232
RPL28 ribosomal protein L28 1.70029
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.67868
SEC61G Sec61 gamma subunit 1.66486
IRAK1 interleukin-1 receptor-associated kinase 1 1.661
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.65372
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.64058
SFXN1 sideroflexin 1 1.62972
TMEM147 transmembrane protein 147 1.61437
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 1.61202
FAM198B family with sequence similarity 198, member B 1.61135
RPS9 ribosomal protein S9 1.60014
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 1.59037
EPS8L2 EPS8-like 2 1.58567
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.58178
CYC1 cytochrome c-1 1.58003
PHTF1 putative homeodomain transcription factor 1 1.57802
PHB2 prohibitin 2 1.5773
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.55722
SEC13 SEC13 homolog (S. cerevisiae) 1.54484
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.53669
DPY30 dpy-30 homolog (C. elegans) 1.52407
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.51716
RPAP2 RNA polymerase II associated protein 2 1.5128
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.50678
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.50153
SYT3 synaptotagmin III 1.49677
RHOQ ras homolog family member Q 1.49384
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.47942
UBXN4 UBX domain protein 4 1.46934
NUDCD1 NudC domain containing 1 1.46447
BST1 bone marrow stromal cell antigen 1 1.46437
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.46308
NEK7 NIMA-related kinase 7 1.462
EIF5A eukaryotic translation initiation factor 5A 1.45571
PRDX3 peroxiredoxin 3 1.43994
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.43304
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.43183
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.43041
PRSS23 protease, serine, 23 1.41753
ATXN10 ataxin 10 1.41682
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.41521
MRPS9 mitochondrial ribosomal protein S9 1.41403
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.41021
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.4086
CCNG1 cyclin G1 1.40058
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 1.4002
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.39701
CEP19 centrosomal protein 19kDa 1.38843
WBP1 WW domain binding protein 1 1.38638
HN1L hematological and neurological expressed 1-like 1.37999
CD99L2 CD99 molecule-like 2 1.37271
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.37189
PLA1A phospholipase A1 member A 1.36932
SEC11A SEC11 homolog A (S. cerevisiae) 1.36887
RPL26 ribosomal protein L26 1.36737
RPL38 ribosomal protein L38 1.36552
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.36385
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.36211
RPS21 ribosomal protein S21 1.36181
RPL22 ribosomal protein L22 1.36134
RIN1 Ras and Rab interactor 1 1.35972
SEC24D SEC24 family member D 1.35949
RPS2 ribosomal protein S2 1.35422
RPL24 ribosomal protein L24 1.33455
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.33418
VSTM4 V-set and transmembrane domain containing 4 1.33034
FNTA farnesyltransferase, CAAX box, alpha 1.32949
NACA nascent polypeptide-associated complex alpha subunit 1.32237
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.32223
NR2C2AP nuclear receptor 2C2-associated protein 1.3144
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 1.31323
RPS8 ribosomal protein S8 1.3046
ODC1 ornithine decarboxylase 1 1.30349
MRPL48 mitochondrial ribosomal protein L48 1.30325
RPS14 ribosomal protein S14 1.30208
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.30187
TSNAX translin-associated factor X 1.30121
MRPS21 mitochondrial ribosomal protein S21 1.29361
MRPL45 mitochondrial ribosomal protein L45 1.29296
RPL35 ribosomal protein L35 1.29067
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.28619
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.28581
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.28192
CDK5RAP3 CDK5 regulatory subunit associated protein 3 1.28023
DYNLT3 dynein, light chain, Tctex-type 3 1.27669
RPS16 ribosomal protein S16 1.2765
RNPS1 RNA binding protein S1, serine-rich domain 1.27648
GUK1 guanylate kinase 1 1.2685
RAN RAN, member RAS oncogene family 1.26813
MSI2 musashi RNA-binding protein 2 1.26559
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.26357
COA3 cytochrome c oxidase assembly factor 3 1.26197
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.2588
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 1.25648
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1.25622
RPS17 ribosomal protein S17 1.25072
AAMP angio-associated, migratory cell protein 1.25047
USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse) 1.24788
CAPRIN1 cell cycle associated protein 1 1.24489
SLMO2 slowmo homolog 2 (Drosophila) 1.24397
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.23874
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 1.23851
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 1.23841
ICT1 immature colon carcinoma transcript 1 1.23097
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.2298
MED25 mediator complex subunit 25 1.22763
SYAP1 synapse associated protein 1 1.22052
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.21625
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 1.21599
PAIP1 poly(A) binding protein interacting protein 1 1.21596
MORF4L2 mortality factor 4 like 2 1.21535
EMC4 ER membrane protein complex subunit 4 1.21201
MRPL20 mitochondrial ribosomal protein L20 1.21184
FAM58A family with sequence similarity 58, member A 1.20682
STAMBP STAM binding protein 1.20369
OXCT1 3-oxoacid CoA transferase 1 1.20015
BSG basigin (Ok blood group) 1.19682
APIP APAF1 interacting protein 1.19209
NMT1 N-myristoyltransferase 1 1.1847
RPL23 ribosomal protein L23 1.18326
BUB3 BUB3 mitotic checkpoint protein 1.18286
FAM98A family with sequence similarity 98, member A 1.18244
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.17807
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 1.17511
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 1.1734
SSBP3 single stranded DNA binding protein 3 1.17118
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 1.1708
SLC30A7 solute carrier family 30 (zinc transporter), member 7 1.16708
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.16646
CACUL1 CDK2-associated, cullin domain 1 1.16303
COPS5 COP9 signalosome subunit 5 1.15851
NLN neurolysin (metallopeptidase M3 family) 1.15288
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.15257
RANGAP1 Ran GTPase activating protein 1 1.15099
RPL18 ribosomal protein L18 1.14855
RPS15 ribosomal protein S15 1.14178
GNG10 guanine nucleotide binding protein (G protein), gamma 10 1.14163
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1.13863
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.13327
MLX MLX, MAX dimerization protein 1.13129
EIF3F eukaryotic translation initiation factor 3, subunit F 1.12427
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 1.12219
RPL10A ribosomal protein L10a 1.12126
RPS6 ribosomal protein S6 1.12075
RPL8 ribosomal protein L8 1.11964
ARL1 ADP-ribosylation factor-like 1 1.11963
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.11916
LRRC42 leucine rich repeat containing 42 1.11807
HDGF hepatoma-derived growth factor 1.11683
FDX1L ferredoxin 1-like 1.1165
RPS26 ribosomal protein S26 1.11626
COL4A5 collagen, type IV, alpha 5 1.11436
NME7 NME/NM23 family member 7 1.11127
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 1.10985
RPS20 ribosomal protein S20 1.10948
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.1073
DSTN destrin (actin depolymerizing factor) 1.10398
H1FX H1 histone family, member X 1.09698
EMC6 ER membrane protein complex subunit 6 1.09604
HBP1 HMG-box transcription factor 1 1.08695
DCAKD dephospho-CoA kinase domain containing 1.08662
SSR4 signal sequence receptor, delta 1.0841
POLR1C polymerase (RNA) I polypeptide C, 30kDa 1.07761
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) 1.07721
MRPS27 mitochondrial ribosomal protein S27 1.07282
RPS27L ribosomal protein S27-like 1.07104
EIF2D eukaryotic translation initiation factor 2D 1.06857
AP3M1 adaptor-related protein complex 3, mu 1 subunit 1.0668
NHP2 NHP2 ribonucleoprotein 1.06613
MSL3 male-specific lethal 3 homolog (Drosophila) 1.06601
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 1.06462
SEC61B Sec61 beta subunit 1.06244
TELO2 telomere maintenance 2 1.05955
NUP88 nucleoporin 88kDa 1.05678
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.05665
WNT4 wingless-type MMTV integration site family, member 4 1.0564
RPS15A ribosomal protein S15a 1.05623
RPL17 ribosomal protein L17 1.04692
KARS lysyl-tRNA synthetase 1.04688
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 1.04506
LEPROTL1 leptin receptor overlapping transcript-like 1 1.04469
CHPF chondroitin polymerizing factor 1.04373
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.0436
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1.04279
NTAN1 N-terminal asparagine amidase 1.03578
VCL vinculin 1.03474
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 1.03375
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 1.03007
PFDN1 prefoldin subunit 1 1.02927
COPE coatomer protein complex, subunit epsilon 1.0281
GDI2 GDP dissociation inhibitor 2 1.02716
CTNNBL1 catenin, beta like 1 1.02632
RPL12 ribosomal protein L12 1.0236
RHBDD3 rhomboid domain containing 3 1.0212
NT5E 5'-nucleotidase, ecto (CD73) 1.02016
RPSA ribosomal protein SA 1.01813
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 1.01728
IGFBP7 insulin-like growth factor binding protein 7 1.01203
REPS1 RALBP1 associated Eps domain containing 1 1.01126
XPO1 exportin 1 1.00836
TXNDC17 thioredoxin domain containing 17 1.00646
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.00593
CD247 CD247 molecule 1.00485
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.00307
PMM1 phosphomannomutase 1 1.00057
GRSF1 G-rich RNA sequence binding factor 1 0.993861
CGNL1 cingulin-like 1 0.993399
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.991835
INA internexin neuronal intermediate filament protein, alpha 0.99015
MRPL18 mitochondrial ribosomal protein L18 0.989738
EIF3H eukaryotic translation initiation factor 3, subunit H 0.98737
MORF4L1 mortality factor 4 like 1 0.984793
UNC119B unc-119 homolog B (C. elegans) 0.984361
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.982967
RPL27A ribosomal protein L27a 0.982055
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.981282
NFYB nuclear transcription factor Y, beta 0.980135
LITAF lipopolysaccharide-induced TNF factor 0.97873
PUS1 pseudouridylate synthase 1 0.977575

decreased expression

Symbol Name Standardized Value
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -4.88832
RGS3 regulator of G-protein signaling 3 -3.74225
PAPD7 PAP associated domain containing 7 -3.72767
PLK2 polo-like kinase 2 -3.70268
TSPAN14 tetraspanin 14 -3.54428
RARB retinoic acid receptor, beta -3.45282
REEP1 receptor accessory protein 1 -3.42917
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -3.37386
NXN nucleoredoxin -3.36524
SDPR serum deprivation response -3.354
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 -3.09239
SFT2D1 SFT2 domain containing 1 -3.0729
NT5C3A 5'-nucleotidase, cytosolic IIIA -2.89136
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.86557
LATS2 large tumor suppressor kinase 2 -2.79472
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -2.77587
UFL1 UFM1-specific ligase 1 -2.74136
FEM1C fem-1 homolog c (C. elegans) -2.69796
DEPDC5 DEP domain containing 5 -2.6832
ZBTB39 zinc finger and BTB domain containing 39 -2.58368
MAK16 MAK16 homolog (S. cerevisiae) -2.57809
GLRA2 glycine receptor, alpha 2 -2.56901
RABAC1 Rab acceptor 1 (prenylated) -2.55645
ZNF318 zinc finger protein 318 -2.54655
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -2.5321
DMWD dystrophia myotonica, WD repeat containing -2.5319
SORBS3 sorbin and SH3 domain containing 3 -2.51739
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.5157
NCAPH2 non-SMC condensin II complex, subunit H2 -2.50982
EGR1 early growth response 1 -2.4813
SH2D3C SH2 domain containing 3C -2.48105
UBQLN4 ubiquilin 4 -2.42986
PPIG peptidylprolyl isomerase G (cyclophilin G) -2.40906
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -2.38858
URGCP upregulator of cell proliferation -2.38538
XPO7 exportin 7 -2.38504
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -2.36456
PACS1 phosphofurin acidic cluster sorting protein 1 -2.35729
SEC63 SEC63 homolog (S. cerevisiae) -2.34464
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -2.34451
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -2.31839
TNXB tenascin XB -2.318
DPF2 D4, zinc and double PHD fingers family 2 -2.31657
DSCR3 Down syndrome critical region 3 -2.29469
TSPAN7 tetraspanin 7 -2.28235
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -2.27991
VASH1 vasohibin 1 -2.27976
CD81 CD81 molecule -2.26701
NOL6 nucleolar protein 6 (RNA-associated) -2.26089
CADPS2 Ca++-dependent secretion activator 2 -2.18036
CTCF CCCTC-binding factor (zinc finger protein) -2.17265
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.15388
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.12388
COMMD9 COMM domain containing 9 -2.07618
SOCS3 suppressor of cytokine signaling 3 -2.07559
FBXL19 F-box and leucine-rich repeat protein 19 -2.06804
EXOC6B exocyst complex component 6B -2.05273
TBKBP1 TBK1 binding protein 1 -2.04558
GALK2 galactokinase 2 -2.03791
NOD1 nucleotide-binding oligomerization domain containing 1 -2.00457
STOM stomatin -1.97616
ALPI alkaline phosphatase, intestinal -1.96738
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -1.95855
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -1.92582
STK24 serine/threonine kinase 24 -1.92534
PRDM2 PR domain containing 2, with ZNF domain -1.91928
FYTTD1 forty-two-three domain containing 1 -1.91891
NPR1 natriuretic peptide receptor 1 -1.90789
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -1.89288
TMEM140 transmembrane protein 140 -1.89257
UBC ubiquitin C -1.8897
VTA1 vesicle (multivesicular body) trafficking 1 -1.87221
ENG endoglin -1.8682
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3 -1.86018
FAM63A family with sequence similarity 63, member A -1.85299
RAB11A RAB11A, member RAS oncogene family -1.82827
LIPE lipase, hormone-sensitive -1.81792
SLC25A45 solute carrier family 25, member 45 -1.80945
LAMP2 lysosomal-associated membrane protein 2 -1.79714
PGM1 phosphoglucomutase 1 -1.79687
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -1.78282
TRAPPC6B trafficking protein particle complex 6B -1.76985
JRK Jrk homolog (mouse) -1.75599
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -1.75012
FBXW8 F-box and WD repeat domain containing 8 -1.74674
USP54 ubiquitin specific peptidase 54 -1.72801
PSAP prosaposin -1.72554
TMEM128 transmembrane protein 128 -1.70585
TINAGL1 tubulointerstitial nephritis antigen-like 1 -1.68798
BLVRA biliverdin reductase A -1.6758
ARRDC4 arrestin domain containing 4 -1.6703
TDRD7 tudor domain containing 7 -1.66966
ADIPOR1 adiponectin receptor 1 -1.66757
ZBTB4 zinc finger and BTB domain containing 4 -1.66709
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.63513
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -1.63443
VEZF1 vascular endothelial zinc finger 1 -1.62596
RABGAP1 RAB GTPase activating protein 1 -1.62581
ITM2C integral membrane protein 2C -1.62523
SLC38A10 solute carrier family 38, member 10 -1.62037
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -1.61895
ESAM endothelial cell adhesion molecule -1.61773
VPS9D1 VPS9 domain containing 1 -1.61116
GATA2 GATA binding protein 2 -1.60169
EML1 echinoderm microtubule associated protein like 1 -1.59343
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -1.59259
XPOT exportin, tRNA -1.58864
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -1.58464
LDB1 LIM domain binding 1 -1.58279
FAM160B2 family with sequence similarity 160, member B2 -1.57378
TXNIP thioredoxin interacting protein -1.56836
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -1.56796
SPATA7 spermatogenesis associated 7 -1.56504
TMED4 transmembrane emp24 protein transport domain containing 4 -1.56
HYAL2 hyaluronoglucosaminidase 2 -1.55838
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -1.55323
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -1.533
RAB11B RAB11B, member RAS oncogene family -1.53183
SP140 SP140 nuclear body protein -1.52909
NUMB numb homolog (Drosophila) -1.52009
FAM43A family with sequence similarity 43, member A -1.5182
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -1.51316
TRAPPC4 trafficking protein particle complex 4 -1.50546
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.4955
RBMS1 RNA binding motif, single stranded interacting protein 1 -1.49328
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.49117
VAMP3 vesicle-associated membrane protein 3 -1.48715
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.48206
SOX13 SRY (sex determining region Y)-box 13 -1.48161
KIDINS220 kinase D-interacting substrate, 220kDa -1.48152
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 -1.47858
SCAMP1 secretory carrier membrane protein 1 -1.46996
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.46972
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -1.45931
HIATL1 hippocampus abundant transcript-like 1 -1.45873
CPD carboxypeptidase D -1.45797
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) -1.45618
EXOC2 exocyst complex component 2 -1.44348
INO80 INO80 complex subunit -1.44249
TMEM55B transmembrane protein 55B -1.44131
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -1.43871
MAEA macrophage erythroblast attacher -1.42613
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -1.42537
TCHP trichoplein, keratin filament binding -1.42428
ARSA arylsulfatase A -1.4204
PNLIP pancreatic lipase -1.41758
CENPV centromere protein V -1.41484
FBXW4 F-box and WD repeat domain containing 4 -1.40304
JUN jun proto-oncogene -1.39761
TSPAN12 tetraspanin 12 -1.39444
TAOK2 TAO kinase 2 -1.39421
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -1.39379
BTG2 BTG family, member 2 -1.38514
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -1.38335
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -1.38097
TM9SF2 transmembrane 9 superfamily member 2 -1.37556
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -1.36778
SMTN smoothelin -1.36572
HIP1 huntingtin interacting protein 1 -1.36479
OCEL1 occludin/ELL domain containing 1 -1.36463
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -1.36189
AFAP1L1 actin filament associated protein 1-like 1 -1.3611
CDH5 cadherin 5, type 2 (vascular endothelium) -1.35694
LRRC58 leucine rich repeat containing 58 -1.35104
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.35069
ITM2B integral membrane protein 2B -1.35013
CDK13 cyclin-dependent kinase 13 -1.34777
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -1.34591
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -1.34201
ERP44 endoplasmic reticulum protein 44 -1.33612
CTBP1 C-terminal binding protein 1 -1.33569
PLD1 phospholipase D1, phosphatidylcholine-specific -1.3337
RAB3D RAB3D, member RAS oncogene family -1.33083
LYPLA2 lysophospholipase II -1.3276
PSKH1 protein serine kinase H1 -1.32705
TBC1D14 TBC1 domain family, member 14 -1.32331
GGT5 gamma-glutamyltransferase 5 -1.32
LY6E lymphocyte antigen 6 complex, locus E -1.31843
ATRNL1 attractin-like 1 -1.31328
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.31289
OAZ2 ornithine decarboxylase antizyme 2 -1.30982
SYNE1 spectrin repeat containing, nuclear envelope 1 -1.30944
EMID1 EMI domain containing 1 -1.30498
ITFG1 integrin alpha FG-GAP repeat containing 1 -1.30148
SLC31A2 solute carrier family 31 (copper transporter), member 2 -1.29194
SUMO1 small ubiquitin-like modifier 1 -1.29118
CNR2 cannabinoid receptor 2 (macrophage) -1.28891
PTPRR protein tyrosine phosphatase, receptor type, R -1.28526
SLC35E4 solute carrier family 35, member E4 -1.285
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 -1.28317
LPCAT3 lysophosphatidylcholine acyltransferase 3 -1.28007
FLCN folliculin -1.27092
ZFP36 ZFP36 ring finger protein -1.26928
GRID1 glutamate receptor, ionotropic, delta 1 -1.26746
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -1.26545
TRAPPC10 trafficking protein particle complex 10 -1.26403
TACC1 transforming, acidic coiled-coil containing protein 1 -1.25754
FBXL3 F-box and leucine-rich repeat protein 3 -1.25718
GANAB glucosidase, alpha; neutral AB -1.2554
BMP2 bone morphogenetic protein 2 -1.25496
TM2D3 TM2 domain containing 3 -1.25435
PEX13 peroxisomal biogenesis factor 13 -1.25328
CLTC clathrin, heavy chain (Hc) -1.23599
FITM2 fat storage-inducing transmembrane protein 2 -1.2242
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -1.21931
RAB1A RAB1A, member RAS oncogene family -1.21896
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -1.21261
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.21179
GADD45G growth arrest and DNA-damage-inducible, gamma -1.20417
ZCCHC6 zinc finger, CCHC domain containing 6 -1.19925
PDE2A phosphodiesterase 2A, cGMP-stimulated -1.19483
FCHO2 FCH domain only 2 -1.19304
KAT7 K(lysine) acetyltransferase 7 -1.19234
ARL15 ADP-ribosylation factor-like 15 -1.18988
GRN granulin -1.18964
UGCG UDP-glucose ceramide glucosyltransferase -1.1849
BCAM basal cell adhesion molecule (Lutheran blood group) -1.18404
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.1838
SURF1 surfeit 1 -1.18216
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.18165
CALML4 calmodulin-like 4 -1.17878
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -1.17763
FBXO7 F-box protein 7 -1.16744
BTBD10 BTB (POZ) domain containing 10 -1.16556
CD48 CD48 molecule -1.16345
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -1.16167
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -1.16037
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -1.15729
FBXO6 F-box protein 6 -1.15724
TMEM88 transmembrane protein 88 -1.15424
MANBA mannosidase, beta A, lysosomal -1.14953
FAM214B family with sequence similarity 214, member B -1.14875
TOM1L2 target of myb1-like 2 (chicken) -1.14641
KAZN kazrin, periplakin interacting protein -1.14558
TCEAL8 transcription elongation factor A (SII)-like 8 -1.1449
MAP2K7 mitogen-activated protein kinase kinase 7 -1.14433
PCM1 pericentriolar material 1 -1.14314
FLYWCH1 FLYWCH-type zinc finger 1 -1.14094
MTF1 metal-regulatory transcription factor 1 -1.14071
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -1.13691
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.1351
SDCBP syndecan binding protein (syntenin) -1.12948
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -1.12866
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -1.1278
GPR182 G protein-coupled receptor 182 -1.12677
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.12192
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.11596
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.11348
MESDC2 mesoderm development candidate 2 -1.1048
ADCY6 adenylate cyclase 6 -1.10321
KLC3 kinesin light chain 3 -1.0984
RHOB ras homolog family member B -1.09716
CEPT1 choline/ethanolamine phosphotransferase 1 -1.09506
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.09505
LIMA1 LIM domain and actin binding 1 -1.09442
KDR kinase insert domain receptor -1.09397
MCOLN1 mucolipin 1 -1.09238
JUNB jun B proto-oncogene -1.09021
GSTP1 glutathione S-transferase pi 1 -1.08979
KANK3 KN motif and ankyrin repeat domains 3 -1.08816
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.08761
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -1.08567
DGAT1 diacylglycerol O-acyltransferase 1 -1.08501
CCDC97 coiled-coil domain containing 97 -1.0845
MTUS1 microtubule associated tumor suppressor 1 -1.08438
TRIP10 thyroid hormone receptor interactor 10 -1.08385
RBM18 RNA binding motif protein 18 -1.07641
ACIN1 apoptotic chromatin condensation inducer 1 -1.07358
USP32 ubiquitin specific peptidase 32 -1.07149
FUNDC2 FUN14 domain containing 2 -1.06586
SNX33 sorting nexin 33 -1.06564
TXNDC15 thioredoxin domain containing 15 -1.05626
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -1.05554
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -1.05552
VEGFB vascular endothelial growth factor B -1.05243
ERCC2 excision repair cross-complementation group 2 -1.05097
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -1.04987
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.0486
USP28 ubiquitin specific peptidase 28 -1.04794
RADIL Ras association and DIL domains -1.04788
TRAPPC8 trafficking protein particle complex 8 -1.04588
ABI2 abl-interactor 2 -1.04449
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 -1.04429
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.04224
ADAM17 ADAM metallopeptidase domain 17 -1.04163
CNRIP1 cannabinoid receptor interacting protein 1 -1.03664
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha -1.03372
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -1.03252
PTDSS1 phosphatidylserine synthase 1 -1.02936
TRAPPC9 trafficking protein particle complex 9 -1.02912
CR1L complement component (3b/4b) receptor 1-like -1.02826
ZEB1 zinc finger E-box binding homeobox 1 -1.02804
USP47 ubiquitin specific peptidase 47 -1.02401
ELF2 E74-like factor 2 (ets domain transcription factor) -1.01985
KLHL22 kelch-like family member 22 -1.01934
NEURL4 neuralized E3 ubiquitin protein ligase 4 -1.01663
PDCD7 programmed cell death 7 -1.01488
ACSL5 acyl-CoA synthetase long-chain family member 5 -1.01298
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 -1.01114
BACE2 beta-site APP-cleaving enzyme 2 -1.01041