Hematologic Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D019337
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Genes

100 genes/proteins associated with the disease Hematologic Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.88009
PON1 paraoxonase 1 2.88009
ETV6 ets variant 6 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
BCL2 B-cell CLL/lymphoma 2 1.74119
PARP1 poly (ADP-ribose) polymerase 1 1.69189
BAX BCL2-associated X protein 1.68782
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.68169
TOP2A topoisomerase (DNA) II alpha 170kDa 1.67483
H2AFX H2A histone family, member X 1.67483
RAD51 RAD51 recombinase 1.66124
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.65996
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.63653
TP53 tumor protein p53 1.60128
GSTM1 glutathione S-transferase mu 1 1.5433
ATM ATM serine/threonine kinase 1.47889
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.45484
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45458
BCL2L1 BCL2-like 1 1.45431
GSTP1 glutathione S-transferase pi 1 1.44653
GADD45A growth arrest and DNA-damage-inducible, alpha 1.44572
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.41559
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.34489
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.3314
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.32044
HBB hemoglobin, beta 1.27813
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.27657
FAS Fas cell surface death receptor 1.27255
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.2596
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.25028
JUN jun proto-oncogene 1.24966
KLF6 Kruppel-like factor 6 1.24591
TNF tumor necrosis factor 1.24087
BBC3 BCL2 binding component 3 1.22306
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.22177
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.20196
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.19639
AXL AXL receptor tyrosine kinase 1.19607
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.19345
HIST1H1C histone cluster 1, H1c 1.19345
ERBB2 erb-b2 receptor tyrosine kinase 2 1.18554
CHEK1 checkpoint kinase 1 1.18126
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.17629
CD44 CD44 molecule (Indian blood group) 1.17333
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.17
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.167
TYMS thymidylate synthetase 1.15223
NQO1 NAD(P)H dehydrogenase, quinone 1 1.14885
PPARG peroxisome proliferator-activated receptor gamma 1.1485
MT1A metallothionein 1A 1.1485
FYN FYN proto-oncogene, Src family tyrosine kinase 1.14678
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.13552
CDKN2A cyclin-dependent kinase inhibitor 2A 1.12703
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.12599
PTEN phosphatase and tensin homolog 1.12048
VEGFA vascular endothelial growth factor A 1.11809
GJA1 gap junction protein, alpha 1, 43kDa 1.11501
STAT1 signal transducer and activator of transcription 1, 91kDa 1.11501
CCND1 cyclin D1 1.1136
VIM vimentin 1.1129
SOD2 superoxide dismutase 2, mitochondrial 1.10977
ERCC1 excision repair cross-complementation group 1 1.10388
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.09857
EGFR epidermal growth factor receptor 1.09611
GSTA1 glutathione S-transferase alpha 1 1.09011
BID BH3 interacting domain death agonist 1.07947
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.07911
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.07447
PELI1 pellino E3 ubiquitin protein ligase 1 1.07057
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.07057
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.06771
FOS FBJ murine osteosarcoma viral oncogene homolog 1.06625
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.06479
CA12 carbonic anhydrase XII 1.05972
RUNX3 runt-related transcription factor 3 1.05972
EPO erythropoietin 1.05237
APAF1 apoptotic peptidase activating factor 1 1.052
THBS1 thrombospondin 1 1.05052
DUSP2 dual specificity phosphatase 2 1.04941
STOM stomatin 1.04647
CDK1 cyclin-dependent kinase 1 1.04501
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.04276
SRGN serglycin 1.04239
BIRC2 baculoviral IAP repeat containing 2 1.04163
TP53I3 tumor protein p53 inducible protein 3 1.03976
NBN nibrin 1.03976
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.03864
TXNIP thioredoxin interacting protein 1.03567
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.03456
CCND3 cyclin D3 1.03419
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.03009
CHEK2 checkpoint kinase 2 1.02896
BRCA1 breast cancer 1, early onset 1.02708
BAK1 BCL2-antagonist/killer 1 1.02596
BTG3 BTG family, member 3 1.02077
F3 coagulation factor III (thromboplastin, tissue factor) 1.01625
CXCR4 chemokine (C-X-C motif) receptor 4 1.01625
PROCR protein C receptor, endothelial 1.01512
XPC xeroderma pigmentosum, complementation group C 1.01286
CRABP2 cellular retinoic acid binding protein 2 1.01025