Heart Arrest Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006323
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Genes

346 genes/proteins associated with the disease Heart Arrest from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
INS insulin 2.88009
TNF tumor necrosis factor 2.88009
IFNG interferon, gamma 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.52095
REN renin 2.48614
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.46173
FOS FBJ murine osteosarcoma viral oncogene homolog 2.43262
IL6 interleukin 6 2.42006
IL1B interleukin 1, beta 2.41538
MAPK1 mitogen-activated protein kinase 1 2.4106
NPPA natriuretic peptide A 2.40698
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.40081
MAPK3 mitogen-activated protein kinase 3 2.39055
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.38832
BCL2 B-cell CLL/lymphoma 2 2.37522
CAT catalase 2.36827
NOS2 nitric oxide synthase 2, inducible 2.34587
BAX BCL2-associated X protein 2.32908
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.31081
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.30925
POMC proopiomelanocortin 2.23095
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.22741
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.22161
PRL prolactin 2.1973
BDNF brain-derived neurotrophic factor 2.17227
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.16121
IL10 interleukin 10 2.15467
EDN1 endothelin 1 2.13963
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.13761
ADRB2 adrenoceptor beta 2, surface 2.12877
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.10907
VEGFA vascular endothelial growth factor A 2.09741
CCL2 chemokine (C-C motif) ligand 2 2.08882
ADRB1 adrenoceptor beta 1 2.085
EGR1 early growth response 1 2.07672
NPY neuropeptide Y 2.05796
CXCL8 chemokine (C-X-C motif) ligand 8 2.04767
FAS Fas cell surface death receptor 2.03278
TGFB1 transforming growth factor, beta 1 2.01938
AVP arginine vasopressin 2.01567
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.00773
JUN jun proto-oncogene 1.98139
DRD2 dopamine receptor D2 1.97566
CALCA calcitonin-related polypeptide alpha 1.96964
CRH corticotropin releasing hormone 1.96224
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.95843
ICAM1 intercellular adhesion molecule 1 1.94642
DRD1 dopamine receptor D1 1.94311
HMOX1 heme oxygenase 1 1.94171
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.9403
NOS3 nitric oxide synthase 3 (endothelial cell) 1.93628
SOD2 superoxide dismutase 2, mitochondrial 1.92532
MAPK8 mitogen-activated protein kinase 8 1.91435
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.90525
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.90242
NGF nerve growth factor (beta polypeptide) 1.90175
TAC1 tachykinin, precursor 1 1.89976
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.88688
TH tyrosine hydroxylase 1.84233
NPPB natriuretic peptide B 1.84073
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.83753
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.83592
IL2 interleukin 2 1.82394
SOD1 superoxide dismutase 1, soluble 1.81793
MAOA monoamine oxidase A 1.81167
MMP9 matrix metallopeptidase 9 1.8113
TP53 tumor protein p53 1.81111
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.80849
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.7759
PARP1 poly (ADP-ribose) polymerase 1 1.77316
BCL2L1 BCL2-like 1 1.7652
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.76462
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.7623
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.7554
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.7554
VCAM1 vascular cell adhesion molecule 1 1.75301
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.74541
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.74541
TIMP1 TIMP metallopeptidase inhibitor 1 1.73598
NUPR1 nuclear protein, transcriptional regulator, 1 1.73008
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.72884
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.71789
MPO myeloperoxidase 1.68804
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.68782
OXT oxytocin/neurophysin I prepropeptide 1.68337
GSK3B glycogen synthase kinase 3 beta 1.68232
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.68106
CLU clusterin 1.67569
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.66986
IL1A interleukin 1, alpha 1.64416
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.64168
GSTP1 glutathione S-transferase pi 1 1.6325
PENK proenkephalin 1.63161
COL1A1 collagen, type I, alpha 1 1.6249
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.61224
FGF2 fibroblast growth factor 2 (basic) 1.59873
GFAP glial fibrillary acidic protein 1.59638
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.59218
IL12B interleukin 12B 1.58983
EGFR epidermal growth factor receptor 1.58889
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.58842
MMP2 matrix metallopeptidase 2 1.58678
IL4 interleukin 4 1.58678
TGFB2 transforming growth factor, beta 2 1.58444
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.58351
CREB1 cAMP responsive element binding protein 1 1.5641
CCND1 cyclin D1 1.55846
IGF1 insulin-like growth factor 1 (somatomedin C) 1.55206
MAP2K1 mitogen-activated protein kinase kinase 1 1.55035
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.54986
PRKCE protein kinase C, epsilon 1.54718
CREM cAMP responsive element modulator 1.53892
LEP leptin 1.53481
CXCL2 chemokine (C-X-C motif) ligand 2 1.53061
GH1 growth hormone 1 1.51886
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.51708
FASLG Fas ligand (TNF superfamily, member 6) 1.51708
MAPK14 mitogen-activated protein kinase 14 1.5103
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.50273
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.49941
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.49941
OPRM1 opioid receptor, mu 1 1.49711
CTSL cathepsin L 1.4966
DUSP1 dual specificity phosphatase 1 1.49609
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.49096
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.48916
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.48248
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.48093
F3 coagulation factor III (thromboplastin, tissue factor) 1.47813
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.47452
DDIT3 DNA-damage-inducible transcript 3 1.47038
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.46807
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.46093
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.46067
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.46067
CYCS cytochrome c, somatic 1.45962
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.45537
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.44735
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.44544
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.4449
PER1 period circadian clock 1 1.44111
ACHE acetylcholinesterase (Yt blood group) 1.43618
RYR2 ryanodine receptor 2 (cardiac) 1.42481
NOS1 nitric oxide synthase 1 (neuronal) 1.41505
STAR steroidogenic acute regulatory protein 1.41202
ARC activity-regulated cytoskeleton-associated protein 1.41008
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.40787
ADRB3 adrenoceptor beta 3 1.4026
GNAS GNAS complex locus 1.40204
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.40204
PLCG1 phospholipase C, gamma 1 1.39897
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.39535
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.39338
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.39086
S100A9 S100 calcium binding protein A9 1.38185
IL12A interleukin 12A 1.381
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.37705
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.37418
APP amyloid beta (A4) precursor protein 1.37389
HOMER1 homer scaffolding protein 1 1.37246
SPP1 secreted phosphoprotein 1 1.3699
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.36791
JUNB jun B proto-oncogene 1.36735
RGS2 regulator of G-protein signaling 2 1.35991
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.35991
TLR4 toll-like receptor 4 1.35618
GJA1 gap junction protein, alpha 1, 43kDa 1.35242
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.35127
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.34343
FNDC4 fibronectin type III domain containing 4 1.3385
GCG glucagon 1.33791
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.33791
CYR61 cysteine-rich, angiogenic inducer, 61 1.32369
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.31596
PRLR prolactin receptor 1.3039
LDLR low density lipoprotein receptor 1.3039
ALB albumin 1.29905
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.29812
PRKCA protein kinase C, alpha 1.29781
GCLC glutamate-cysteine ligase, catalytic subunit 1.28765
C10ORF10 chromosome 10 open reading frame 10 1.28549
FOSL2 FOS-like antigen 2 1.28425
CCL3 chemokine (C-C motif) ligand 3 1.28241
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.27595
GSTM3 glutathione S-transferase mu 3 (brain) 1.27595
BIRC5 baculoviral IAP repeat containing 5 1.27502
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.27132
IL18 interleukin 18 1.26856
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.26669
G6PD glucose-6-phosphate dehydrogenase 1.26669
BAD BCL2-associated agonist of cell death 1.26669
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.26329
GADD45A growth arrest and DNA-damage-inducible, alpha 1.26267
DDIT4 DNA-damage-inducible transcript 4 1.26021
FN1 fibronectin 1 1.25838
ACE angiotensin I converting enzyme 1.25807
S100A8 S100 calcium binding protein A8 1.25059
ADRA1B adrenoceptor alpha 1B 1.24966
THY1 Thy-1 cell surface antigen 1.24905
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.24812
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.24307
PRKCD protein kinase C, delta 1.24087
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.23993
PPARA peroxisome proliferator-activated receptor alpha 1.23265
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.23074
GPX1 glutathione peroxidase 1 1.23074
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.22758
FOXO1 forkhead box O1 1.22404
CFLAR CASP8 and FADD-like apoptosis regulator 1.22274
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 1.22145
LPL lipoprotein lipase 1.21695
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.21695
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.21468
MSMO1 methylsterol monooxygenase 1 1.21173
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.21011
COMT catechol-O-methyltransferase 1.21011
LHB luteinizing hormone beta polypeptide 1.20816
COL3A1 collagen, type III, alpha 1 1.20784
PCNA proliferating cell nuclear antigen 1.20687
EDNRB endothelin receptor type B 1.20526
ACTA2 actin, alpha 2, smooth muscle, aorta 1.19999
GSTM2 glutathione S-transferase mu 2 (muscle) 1.19999
HDC histidine decarboxylase 1.19574
CHRM4 cholinergic receptor, muscarinic 4 1.19246
EGF epidermal growth factor 1.19146
TAGLN transgelin 1.1908
SGK1 serum/glucocorticoid regulated kinase 1 1.18882
GAL galanin/GMAP prepropeptide 1.18816
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.18193
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.17728
NTF3 neurotrophin 3 1.17728
SQLE squalene epoxidase 1.17629
EGR2 early growth response 2 1.17366
CAPN2 calpain 2, (m/II) large subunit 1.17366
ADRA1D adrenoceptor alpha 1D 1.17235
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.17134
PLAT plasminogen activator, tissue 1.17134
ADRA2A adrenoceptor alpha 2A 1.17
ACTB actin, beta 1.16833
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.166
CES2 carboxylesterase 2 1.16269
ORM2 orosomucoid 2 1.16269
ARRB2 arrestin, beta 2 1.16269
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.15729
INHBE inhibin, beta E 1.15593
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.15391
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.15324
PKLR pyruvate kinase, liver and RBC 1.15256
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.15189
CTSD cathepsin D 1.15089
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.15089
S100B S100 calcium binding protein B 1.14919
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.14747
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.14644
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.14575
JAK1 Janus kinase 1 1.14234
GAP43 growth associated protein 43 1.14234
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.13997
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.13862
CP ceruloplasmin (ferroxidase) 1.13793
EPO erythropoietin 1.13586
APAF1 apoptotic peptidase activating factor 1 1.13586
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.13586
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.13518
ODC1 ornithine decarboxylase 1 1.13518
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.12838
CHRM3 cholinergic receptor, muscarinic 3 1.12599
ERP29 endoplasmic reticulum protein 29 1.12219
OPRK1 opioid receptor, kappa 1 1.11945
S100A4 S100 calcium binding protein A4 1.11639
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.11571
GHRL ghrelin/obestatin prepropeptide 1.1136
KDR kinase insert domain receptor 1.11151
CXCL10 chemokine (C-X-C motif) ligand 10 1.11151
KLF4 Kruppel-like factor 4 (gut) 1.11011
ADCY5 adenylate cyclase 5 1.10977
GSR glutathione reductase 1.10769
IL2RA interleukin 2 receptor, alpha 1.10699
ANXA1 annexin A1 1.10631
VCAN versican 1.1014
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.09822
HRH1 histamine receptor H1 1.09786
MAPK9 mitogen-activated protein kinase 9 1.09646
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.09262
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.0894
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.08904
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.08442
SCN5A sodium channel, voltage gated, type V alpha subunit 1.08161
HSPA8 heat shock 70kDa protein 8 1.08055
CTGF connective tissue growth factor 1.07875
MMP1 matrix metallopeptidase 1 1.07875
MMP13 matrix metallopeptidase 13 1.07804
GATA4 GATA binding protein 4 1.07768
CDK2 cyclin-dependent kinase 2 1.07589
CES1 carboxylesterase 1 1.07589
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.07447
RGS4 regulator of G-protein signaling 4 1.07411
CCND2 cyclin D2 1.0734
CASP12 caspase 12 (gene/pseudogene) 1.07163
IL5 interleukin 5 1.06952
IGFBP1 insulin-like growth factor binding protein 1 1.06661
GAST gastrin 1.06661
LAMB1 laminin, beta 1 1.06552
CHEK1 checkpoint kinase 1 1.06442
APOE apolipoprotein E 1.06406
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.06297
ANXA4 annexin A4 1.06297
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.06008
PRKCZ protein kinase C, zeta 1.05936
NTS neurotensin 1.05936
ADORA1 adenosine A1 receptor 1.05757
VIM vimentin 1.05685
CAV1 caveolin 1, caveolae protein, 22kDa 1.05573
CYP3A cytochrome P450, family 3, subfamily A 1.05573
IGFBP5 insulin-like growth factor binding protein 5 1.05498
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.05274
FYN FYN proto-oncogene, Src family tyrosine kinase 1.052
BDKRB2 bradykinin receptor B2 1.052
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.052
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.05052
PVALB parvalbumin 1.05015
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.05015
PPARG peroxisome proliferator-activated receptor gamma 1.04978
TFRC transferrin receptor 1.04941
TAT tyrosine aminotransferase 1.04831
RB1 retinoblastoma 1 1.04794
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.04684
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.04538
MMP3 matrix metallopeptidase 3 1.04465
GDNF glial cell derived neurotrophic factor 1.03789
CHRM5 cholinergic receptor, muscarinic 5 1.03752
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.03678
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.03604
TUBA4A tubulin, alpha 4a 1.0353
LDHB lactate dehydrogenase B 1.03419
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.03419
MAOB monoamine oxidase B 1.02559
PRKCB protein kinase C, beta 1.02559
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.0241
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.02151
PDYN prodynorphin 1.02077
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.01701
ADRBK1 adrenergic, beta, receptor kinase 1 1.01625
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.01512
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.01137
POR P450 (cytochrome) oxidoreductase 1.01137