Headache Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve. (Human Phenotype Ontology, HP_0002315)
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Genes

18 genes associated with the Headache phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA2A adenosine A2a receptor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APP amyloid beta (A4) precursor protein
BDNF brain-derived neurotrophic factor
COMT catechol-O-methyltransferase
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DRD4 dopamine receptor D4
EDNRA endothelin receptor type A
ESR2 estrogen receptor 2 (ER beta)
MAOA monoamine oxidase A
POLG polymerase (DNA directed), gamma
PSEN1 presenilin 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
WFS1 Wolfram syndrome 1 (wolframin)