Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5625-01A-01R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

324 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5625-01A-01R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACTRT1 actin-related protein T1
ACY3 aminoacylase 3
ADGRF4 adhesion G protein-coupled receptor F4
ADIPOR1 adiponectin receptor 1
ADPRHL2 ADP-ribosylhydrolase like 2
AKAP5 A kinase (PRKA) anchor protein 5
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPK1 alpha-kinase 1
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANXA4 annexin A4
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
AQP3 aquaporin 3 (Gill blood group)
ARHGAP20 Rho GTPase activating protein 20
ARL15 ADP-ribosylation factor-like 15
ATF6B activating transcription factor 6 beta
BAG5 BCL2-associated athanogene 5
BAK1 BCL2-antagonist/killer 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BLNK B-cell linker
BLZF1 basic leucine zipper nuclear factor 1
BMPR1B bone morphogenetic protein receptor, type IB
BPGM 2,3-bisphosphoglycerate mutase
BTF3L4 basic transcription factor 3-like 4
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A3 butyrophilin, subfamily 3, member A3
C16ORF62 chromosome 16 open reading frame 62
C16ORF72 chromosome 16 open reading frame 72
C1ORF186 chromosome 1 open reading frame 186
C1ORF21 chromosome 1 open reading frame 21
C1S complement component 1, s subcomponent
C22ORF24 chromosome 22 open reading frame 24
C2CD4A C2 calcium-dependent domain containing 4A
C4ORF33 chromosome 4 open reading frame 33
C6ORF106 chromosome 6 open reading frame 106
C6ORF62 chromosome 6 open reading frame 62
C8ORF37 chromosome 8 open reading frame 37
CA2 carbonic anhydrase II
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CC2D1B coiled-coil and C2 domain containing 1B
CCDC71 coiled-coil domain containing 71
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCM2 cerebral cavernous malformation 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD244 CD244 molecule, natural killer cell receptor 2B4
CD274 CD274 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD8A CD8a molecule
CD96 CD96 molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFH complement factor H
CLCA2 chloride channel accessory 2
CLIC2 chloride intracellular channel 2
CLIC4 chloride intracellular channel 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CRYBA2 crystallin, beta A2
CST13P cystatin 13, pseudogene
CTSO cathepsin O
CTSW cathepsin W
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF40B chromosome X open reading frame 40B
CYB5R1 cytochrome b5 reductase 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DCTN4 dynactin 4 (p62)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DERL1 derlin 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DOPEY1 dopey family member 1
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DST dystonin
EFR3A EFR3 homolog A (S. cerevisiae)
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4E3 eukaryotic translation initiation factor 4E family member 3
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELF4 E74-like factor 4 (ets domain transcription factor)
ELL elongation factor RNA polymerase II
EMC2 ER membrane protein complex subunit 2
EPGN epithelial mitogen
EPSTI1 epithelial stromal interaction 1 (breast)
ETV7 ets variant 7
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAM102B family with sequence similarity 102, member B
FAM151B family with sequence similarity 151, member B
FAM213A family with sequence similarity 213, member A
FAM46A family with sequence similarity 46, member A
FAM49B family with sequence similarity 49, member B
FAM76A family with sequence similarity 76, member A
FAM83B family with sequence similarity 83, member B
FAM89B family with sequence similarity 89, member B
FASLG Fas ligand (TNF superfamily, member 6)
FBXO28 F-box protein 28
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEM1C fem-1 homolog c (C. elegans)
FGL2 fibrinogen-like 2
FLJ41941 uncharacterized LOC100192420
FOSL1 FOS-like antigen 1
FZD6 frizzled class receptor 6
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GJA1 gap junction protein, alpha 1, 43kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GLYAT glycine-N-acyltransferase
GMEB1 glucocorticoid modulatory element binding protein 1
GNLY granulysin
GPA33 glycoprotein A33 (transmembrane)
GPBP1L1 GC-rich promoter binding protein 1-like 1
GPR34 G protein-coupled receptor 34
GPR82 G protein-coupled receptor 82
GRN granulin
GSTK1 glutathione S-transferase kappa 1
GTF2B general transcription factor IIB
GUCD1 guanylyl cyclase domain containing 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBP1 HMG-box transcription factor 1
HCAR2 hydroxycarboxylic acid receptor 2
HCCS holocytochrome c synthase
HELB helicase (DNA) B
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIAT1 hippocampus abundant transcript 1
HLA-E major histocompatibility complex, class I, E
HPS6 Hermansky-Pudlak syndrome 6
IFI16 interferon, gamma-inducible protein 16
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL12RB2 interleukin 12 receptor, beta 2
IL13RA1 interleukin 13 receptor, alpha 1
IL18RAP interleukin 18 receptor accessory protein
IL32 interleukin 32
IL6R interleukin 6 receptor
IL7 interleukin 7
INPP1 inositol polyphosphate-1-phosphatase
INTS12 integrator complex subunit 12
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
ITGB7 integrin, beta 7
KANK4 KN motif and ankyrin repeat domains 4
KAT5 K(lysine) acetyltransferase 5
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KIAA0319L KIAA0319-like
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLF10 Kruppel-like factor 10
KLHL13 kelch-like family member 13
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRBA1 KRAB-A domain containing 1
KRTAP6-3 keratin associated protein 6-3
LAMP2 lysosomal-associated membrane protein 2
LAP3 leucine aminopeptidase 3
LINC00032 long intergenic non-protein coding RNA 32
LMO1 LIM domain only 1 (rhombotin 1)
LOC100133050 glucuronidase, beta pseudogene
LOC389705 chromosome 4 open reading frame 27 pseudogene
LRRC16A leucine rich repeat containing 16A
LRRN3 leucine rich repeat neuronal 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2B methionine adenosyltransferase II, beta
MATN2 matrilin 2
MBNL2 muscleblind-like splicing regulator 2
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MIER1 mesoderm induction early response 1, transcriptional regulator
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MMP25 matrix metallopeptidase 25
MSRB1 methionine sulfoxide reductase B1
MTAP methylthioadenosine phosphorylase
MTM1 myotubularin 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUS81 MUS81 structure-specific endonuclease subunit
MYADM myeloid-associated differentiation marker
NCOA7 nuclear receptor coactivator 7
NCR1 natural cytotoxicity triggering receptor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIPAL2 NIPA-like domain containing 2
NMI N-myc (and STAT) interactor
NMRK1 nicotinamide riboside kinase 1
NMRK2 nicotinamide riboside kinase 2
NUB1 negative regulator of ubiquitin-like proteins 1
NUBP1 nucleotide binding protein 1
OPTN optineurin
OR11H12 olfactory receptor, family 11, subfamily H, member 12
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSTM1 osteopetrosis associated transmembrane protein 1
PALLD palladin, cytoskeletal associated protein
PALMD palmdelphin
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PDLIM5 PDZ and LIM domain 5
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHOSPHO1 phosphatase, orphan 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLK3 polo-like kinase 3
PLRG1 pleiotropic regulator 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRAMEF16 PRAME family member 16
PRAMEF19 PRAME family member 19
PRF1 perforin 1 (pore forming protein)
PRSS53 protease, serine, 53
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRK protein tyrosine phosphatase, receptor type, K
PURB purine-rich element binding protein B
PUS10 pseudouridylate synthase 10
RAP2C RAP2C, member of RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RB1CC1 RB1-inducible coiled-coil 1
RDH10 retinol dehydrogenase 10 (all-trans)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REXO2 RNA exonuclease 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF11 ring finger protein 11
RNF139 ring finger protein 139
RNF152 ring finger protein 152
RNF19B ring finger protein 19B
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPAP2 RNA polymerase II associated protein 2
RPP14 ribonuclease P/MRP 14kDa subunit
RRAGC Ras-related GTP binding C
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SGMS1 sphingomyelin synthase 1
SH3RF1 SH3 domain containing ring finger 1
SHISA5 shisa family member 5
SIRPG signal-regulatory protein gamma
SLA2 Src-like-adaptor 2
SLC10A3 solute carrier family 10, member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC44A5 solute carrier family 44, member 5
SLFN5 schlafen family member 5
SMIM14 small integral membrane protein 14
SMPX small muscle protein, X-linked
SNX16 sorting nexin 16
SOS2 son of sevenless homolog 2 (Drosophila)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STIM2 stromal interaction molecule 2
STK17B serine/threonine kinase 17b
STOM stomatin
STX11 syntaxin 11
STX12 syntaxin 12
SZRD1 SUZ RNA binding domain containing 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TESK2 testis-specific kinase 2
TFIP11 tuftelin interacting protein 11
TGS1 trimethylguanosine synthase 1
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGD5 tigger transposable element derived 5
TMEM165 transmembrane protein 165
TMEM179B transmembrane protein 179B
TMEM50A transmembrane protein 50A
TOB2 transducer of ERBB2, 2
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM22 tripartite motif containing 22
TRIM26 tripartite motif containing 26
TRIM36 tripartite motif containing 36
TRIM38 tripartite motif containing 38
TRIM47 tripartite motif containing 47
TRIM69 tripartite motif containing 69
TSHB thyroid stimulating hormone, beta
TSPAN10 tetraspanin 10
TSPAN15 tetraspanin 15
TUSC1 tumor suppressor candidate 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP15 ubiquitin specific peptidase 15
USP24 ubiquitin specific peptidase 24
USP38 ubiquitin specific peptidase 38
USP43 ubiquitin specific peptidase 43
UST uronyl-2-sulfotransferase
VAMP3 vesicle-associated membrane protein 3
VAMP7 vesicle-associated membrane protein 7
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WARS tryptophanyl-tRNA synthetase
WDR25 WD repeat domain 25
WDR37 WD repeat domain 37
WDR44 WD repeat domain 44
WDR64 WD repeat domain 64
XCL2 chemokine (C motif) ligand 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPR1 xenotropic and polytropic retrovirus receptor 1
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBED6CL ZBED6 C-terminal like
ZBTB22 zinc finger and BTB domain containing 22
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZHX1 zinc fingers and homeoboxes 1
ZNF267 zinc finger protein 267
ZNF282 zinc finger protein 282
ZNF410 zinc finger protein 410
ZNF658 zinc finger protein 658
ZNF683 zinc finger protein 683
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZSCAN31 zinc finger and SCAN domain containing 31

low expression

Symbol Name
LDAH lipid droplet associated hydrolase
SMYD5 SMYD family member 5