Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

437 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAM10 ADAM metallopeptidase domain 10
ADAR adenosine deaminase, RNA-specific
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADGRE4P adhesion G protein-coupled receptor E4, pseudogene
AFAP1L2 actin filament associated protein 1-like 2
AFF4 AF4/FMR2 family, member 4
AGO3 argonaute RISC catalytic component 3
AHNAK2 AHNAK nucleoprotein 2
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANO1 anoctamin 1, calcium activated chloride channel
ANXA7 annexin A7
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP29 Rho GTPase activating protein 29
ARHGAP35 Rho GTPase activating protein 35
ARHGAP5 Rho GTPase activating protein 5
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASB7 ankyrin repeat and SOCS box containing 7
ATE1 arginyltransferase 1
ATF7IP activating transcription factor 7 interacting protein
ATG2A autophagy related 2A
ATG2B autophagy related 2B
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP9A ATPase, class II, type 9A
ATXN1 ataxin 1
ATXN1L ataxin 1-like
ATXN3 ataxin 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP2K BMP2 inducible kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMS1 BMS1 ribosome biogenesis factor
BMS1P4 BMS1 ribosome biogenesis factor pseudogene 4
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BTBD7 BTB (POZ) domain containing 7
C17ORF85 chromosome 17 open reading frame 85
C9ORF41 chromosome 9 open reading frame 41
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CCDC97 coiled-coil domain containing 97
CCND1 cyclin D1
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD163L1 CD163 molecule-like 1
CD226 CD226 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD84 CD84 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42SE2 CDC42 small effector 2
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP350 centrosomal protein 350kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHD2 chromodomain helicase DNA binding protein 2
CHD8 chromodomain helicase DNA binding protein 8
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMKLR1 chemerin chemokine-like receptor 1
CNBD2 cyclic nucleotide binding domain containing 2
CNOT6 CCR4-NOT transcription complex, subunit 6
COL22A1 collagen, type XXII, alpha 1
CPM carboxypeptidase M
CREB1 cAMP responsive element binding protein 1
CREG2 cellular repressor of E1A-stimulated genes 2
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1A1P1 casein kinase 1, alpha 1 pseudogene 1
CSNK1G1 casein kinase 1, gamma 1
CTTN cortactin
CYBB cytochrome b-245, beta polypeptide
CYLD cylindromatosis (turban tumor syndrome)
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF5 DDB1 and CUL4 associated factor 5
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCTN4 dynactin 4 (p62)
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND1B DENN/MADD domain containing 1B
DHCR7 7-dehydrocholesterol reductase
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DICER1 dicer 1, ribonuclease type III
DIDO1 death inducer-obliterator 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DMXL2 Dmx-like 2
DNM3 dynamin 3
DOPEY1 dopey family member 1
DPF2 D4, zinc and double PHD fingers family 2
DPYD dihydropyrimidine dehydrogenase
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EFCAB14 EF-hand calcium binding domain 14
EHBP1L1 EH domain binding protein 1-like 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMB embigin
EML5 echinoderm microtubule associated protein like 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA4 EPH receptor A4
ERCC6 excision repair cross-complementation group 6
EXOC5 exocyst complex component 5
FAM126B family with sequence similarity 126, member B
FAM160A1 family with sequence similarity 160, member A1
FAM175B family with sequence similarity 175, member B
FAM208B family with sequence similarity 208, member B
FAM21A family with sequence similarity 21, member A
FAM26E family with sequence similarity 26, member E
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM63B family with sequence similarity 63, member B
FAT2 FAT atypical cadherin 2
FBXO28 F-box protein 28
FBXO45 F-box protein 45
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGL2 fibrinogen-like 2
FLJ12825 uncharacterized LOC440101
FLT4 fms-related tyrosine kinase 4
FPR3 formyl peptide receptor 3
FRMD6 FERM domain containing 6
FRYL FRY-like
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP5 guanylate binding protein 5
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFRA2 GDNF family receptor alpha 2
GLDN gliomedin
GM2A GM2 ganglioside activator
GMFB glia maturation factor, beta
GPATCH2L G patch domain containing 2-like
GPR31 G protein-coupled receptor 31
GPR34 G protein-coupled receptor 34
GPRIN3 GPRIN family member 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCCAT5 hepatocellular carcinoma associated transcript 5 (non-protein coding)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIPK2 homeodomain interacting protein kinase 2
HSPA2 heat shock 70kDa protein 2
HTT huntingtin
ICOS inducible T-cell co-stimulator
IFIH1 interferon induced with helicase C domain 1
IGHMBP2 immunoglobulin mu binding protein 2
IGSF3 immunoglobulin superfamily, member 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL17C interleukin 17C
IL18BP interleukin 18 binding protein
IL1R1 interleukin 1 receptor, type I
INO80D INO80 complex subunit D
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPMK inositol polyphosphate multikinase
ITK IL2-inducible T-cell kinase
JAK1 Janus kinase 1
JARID2 jumonji, AT rich interactive domain 2
JMJD1C jumonji domain containing 1C
KAT5 K(lysine) acetyltransferase 5
KDM2A lysine (K)-specific demethylase 2A
KHNYN KH and NYN domain containing
KIAA0513 KIAA0513
KIAA0586 KIAA0586
KIAA0922 KIAA0922
KIAA1033 KIAA1033
KIAA1109 KIAA1109
KIF1BP KIF1 binding protein
KLHL28 kelch-like family member 28
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLK9 kallikrein-related peptidase 9
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KPNA6 karyopherin alpha 6 (importin alpha 7)
KTN1 kinectin 1 (kinesin receptor)
LATS1 large tumor suppressor kinase 1
LEPROT leptin receptor overlapping transcript
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00207 long intergenic non-protein coding RNA 207
LINC00593 long intergenic non-protein coding RNA 593
LIPK lipase, family member K
LOC100128542
LOC284441 actin-related protein 2 pseudogene
LRRN3 leucine rich repeat neuronal 3
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LTN1 listerin E3 ubiquitin protein ligase 1
LY75 lymphocyte antigen 75
MACF1 microtubule-actin crosslinking factor 1
MAGEA11 melanoma antigen family A11
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK6 mitogen-activated protein kinase 6
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MED13 mediator complex subunit 13
MED29 mediator complex subunit 29
MEFV Mediterranean fever
MFAP3 microfibrillar-associated protein 3
MICU1 mitochondrial calcium uptake 1
MNDA myeloid cell nuclear differentiation antigen
MPEG1 macrophage expressed 1
MTF1 metal-regulatory transcription factor 1
MYO7A myosin VIIA
MYO9A myosin IXA
N4BP1 NEDD4 binding protein 1
N4BP2 NEDD4 binding protein 2
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NADSYN1 NAD synthetase 1
NAIP NLR family, apoptosis inhibitory protein
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NBEAL1 neurobeachin-like 1
NBPF10 neuroblastoma breakpoint family, member 10
NCOA3 nuclear receptor coactivator 3
NCOA4 nuclear receptor coactivator 4
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEK1 NIMA-related kinase 1
NEU2 sialidase 2 (cytosolic sialidase)
NHLRC2 NHL repeat containing 2
NID1 nidogen 1
NLRC5 NLR family, CARD domain containing 5
NOL9 nucleolar protein 9
NOP9 NOP9 nucleolar protein
NOTCH2 notch 2
NPFFR1 neuropeptide FF receptor 1
NPY4R neuropeptide Y receptor Y4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUMA1 nuclear mitotic apparatus protein 1
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
NWD2 NACHT and WD repeat domain containing 2
ODF2L outer dense fiber of sperm tails 2-like
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR4D6 olfactory receptor, family 4, subfamily D, member 6
OR52N1 olfactory receptor, family 52, subfamily N, member 1
OTUD4 OTU deubiquitinase 4
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PALD1 phosphatase domain containing, paladin 1
PANK3 pantothenate kinase 3
PAPL iron/zinc purple acid phosphatase-like protein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PATE1 prostate and testis expressed 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGB1 protocadherin gamma subfamily B, 1
PCNX pecanex homolog (Drosophila)
PCNXL3 pecanex-like 3 (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGM2 phosphoglucomutase 2
PLA2G2F phospholipase A2, group IIF
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PLXNC1 plexin C1
PNMAL1 paraneoplastic Ma antigen family-like 1
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB22A RAB22A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RANBP2 RAN binding protein 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RBM43 RNA binding motif protein 43
RC3H2 ring finger and CCCH-type domains 2
RELN reelin
REST RE1-silencing transcription factor
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RNF213 ring finger protein 213
RNF217 ring finger protein 217
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RUFY2 RUN and FYVE domain containing 2
RWDD2B RWD domain containing 2B
S100A7A S100 calcium binding protein A7A
SAMD8 sterile alpha motif domain containing 8
SAMD9 sterile alpha motif domain containing 9
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SCARB2 scavenger receptor class B, member 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC23IP SEC23 interacting protein
SEC24A SEC24 family member A
SEMG1 semenogelin I
SERINC3 serine incorporator 3
SGMS1 sphingomyelin synthase 1
SGPL1 sphingosine-1-phosphate lyase 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SKIL SKI-like proto-oncogene
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA4 small nucleolar RNA, H/ACA box 4
SNX29 sorting nexin 29
SNX6 sorting nexin 6
SOCS4 suppressor of cytokine signaling 4
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSH2 slingshot protein phosphatase 2
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK4 serine/threonine kinase 4
STRA6 stimulated by retinoic acid 6
STRN3 striatin, calmodulin binding protein 3
STX11 syntaxin 11
STX17 syntaxin 17
STYX serine/threonine/tyrosine interacting protein
SULF2 sulfatase 2
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SUSD6 sushi domain containing 6
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNRG synergin, gamma
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TAS2R3 taste receptor, type 2, member 3
TBC1D2B TBC1 domain family, member 2B
TBCK TBC1 domain containing kinase
TCAF1 TRPM8 channel-associated factor 1
TCF23 transcription factor 23
TFEC transcription factor EC
TIAM1 T-cell lymphoma invasion and metastasis 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLE4 transducin-like enhancer of split 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMEM215 transmembrane protein 215
TMEM245 transmembrane protein 245
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNRC6B trinucleotide repeat containing 6B
TOB2 transducer of ERBB2, 2
TOP1 topoisomerase (DNA) I
TOP1P1 topoisomerase (DNA) I pseudogene 1
TOX4 TOX high mobility group box family member 4
TRAF3 TNF receptor-associated factor 3
TRIM25 tripartite motif containing 25
TRIM5 tripartite motif containing 5
TRIM58 tripartite motif containing 58
TRIP11 thyroid hormone receptor interactor 11
TRIP12 thyroid hormone receptor interactor 12
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSC22D2 TSC22 domain family, member 2
TTPAL tocopherol (alpha) transfer protein-like
TULP4 tubby like protein 4
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UHMK1 U2AF homology motif (UHM) kinase 1
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP15 ubiquitin specific peptidase 15
USP16 ubiquitin specific peptidase 16
USP47 ubiquitin specific peptidase 47
USP48 ubiquitin specific peptidase 48
USP8 ubiquitin specific peptidase 8
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCL vinculin
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WARS tryptophanyl-tRNA synthetase
WDFY1 WD repeat and FYVE domain containing 1
WDR11 WD repeat domain 11
WDR36 WD repeat domain 36
XDH xanthine dehydrogenase
XRN1 5'-3' exoribonuclease 1
YLPM1 YLP motif containing 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFYVE26 zinc finger, FYVE domain containing 26
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF114 zinc finger protein 114
ZNF17 zinc finger protein 17
ZNF200 zinc finger protein 200
ZNF225 zinc finger protein 225
ZNF264 zinc finger protein 264
ZNF283 zinc finger protein 283
ZNF304 zinc finger protein 304
ZNF416 zinc finger protein 416
ZNF460 zinc finger protein 460
ZNF518B zinc finger protein 518B
ZNF543 zinc finger protein 543
ZNF772 zinc finger protein 772
ZNF776 zinc finger protein 776
ZNF845 zinc finger protein 845
ZNFX1 zinc finger, NFX1-type containing 1
ZRANB1 zinc finger, RAN-binding domain containing 1
ZSWIM8 zinc finger, SWIM-type containing 8
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

low expression

Symbol Name
DDA1 DET1 and DDB1 associated 1
ELAVL1 ELAV like RNA binding protein 1