Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

429 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI3 ABI family, member 3
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACAD9 acyl-CoA dehydrogenase family, member 9
ACE angiotensin I converting enzyme
ACP2 acid phosphatase 2, lysosomal
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAM29 ADAM metallopeptidase domain 29
ADGRE5 adhesion G protein-coupled receptor E5
ADORA3 adenosine A3 receptor
ADRM1 adhesion regulating molecule 1
ALG3 ALG3, alpha-1,3- mannosyltransferase
AMOTL2 angiomotin like 2
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC4 apolipoprotein C-IV
APOE apolipoprotein E
APTX aprataxin
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARMC8 armadillo repeat containing 8
ARRB2 arrestin, beta 2
ARRDC1 arrestin domain containing 1
ARSI arylsulfatase family, member I
ASB16-AS1 ASB16 antisense RNA 1
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1
ATG2A autophagy related 2A
ATG3 autophagy related 3
ATP13A2 ATPase type 13A2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
AURKA aurora kinase A
AURKB aurora kinase B
B3GAT1 beta-1,3-glucuronyltransferase 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACE2 beta-site APP-cleaving enzyme 2
BCL9L B-cell CLL/lymphoma 9-like
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BTN3A3 butyrophilin, subfamily 3, member A3
C10ORF113 chromosome 10 open reading frame 113
C11ORF45 chromosome 11 open reading frame 45
C11ORF57 chromosome 11 open reading frame 57
C15ORF53 chromosome 15 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
C17ORF67 chromosome 17 open reading frame 67
C17ORF70 chromosome 17 open reading frame 70
C19ORF35 chromosome 19 open reading frame 35
C1ORF162 chromosome 1 open reading frame 162
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C2 complement component 2
C3AR1 complement component 3a receptor 1
C3ORF17 chromosome 3 open reading frame 17
C3ORF52 chromosome 3 open reading frame 52
C5ORF47 chromosome 5 open reading frame 47
C9ORF139 chromosome 9 open reading frame 139
CAAP1 caspase activity and apoptosis inhibitor 1
CALCOCO2 calcium binding and coiled-coil domain 2
CBWD1 COBW domain containing 1
CBX4 chromobox homolog 4
CCDC171 coiled-coil domain containing 171
CCDC58 coiled-coil domain containing 58
CCDC70 coiled-coil domain containing 70
CCDC84 coiled-coil domain containing 84
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD101 CD101 molecule
CD163 CD163 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD53 CD53 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CD8B CD8b molecule
CD96 CD96 molecule
CDC37L1 cell division cycle 37-like 1
CDH22 cadherin 22, type 2
CDK9 cyclin-dependent kinase 9
CDV3 CDV3 homolog (mouse)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHMP5 charged multivesicular body protein 5
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CLEC4E C-type lectin domain family 4, member E
CLTA clathrin, light chain A
CLUH clustered mitochondria (cluA/CLU1) homolog
CMKLR1 chemerin chemokine-like receptor 1
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNTROB centrobin, centrosomal BRCA2 interacting protein
COASY CoA synthase
COMMD5 COMM domain containing 5
COPG1 coatomer protein complex, subunit gamma 1
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPOX coproporphyrinogen oxidase
CSF1R colony stimulating factor 1 receptor
CTAGE4 CTAGE family, member 4
CTSC cathepsin C
CTSW cathepsin W
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
DAB2IP DAB2 interacting protein
DAGLB diacylglycerol lipase, beta
DBR1 debranching RNA lariats 1
DCAF10 DDB1 and CUL4 associated factor 10
DCAF12 DDB1 and CUL4 associated factor 12
DCTN3 dynactin 3 (p22)
DIRC1 disrupted in renal carcinoma 1
DIRC2 disrupted in renal carcinoma 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DOK2 docking protein 2, 56kDa
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPH1 diphthamide biosynthesis 1
DTX3L deltex 3 like, E3 ubiquitin ligase
DYNLL2 dynein, light chain, LC8-type 2
DZIP1L DAZ interacting zinc finger protein 1-like
EBI3 Epstein-Barr virus induced 3
ECE2 endothelin converting enzyme 2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF4A3 eukaryotic translation initiation factor 4A3
EIF5A2 eukaryotic translation initiation factor 5A2
EIF5AL1 eukaryotic translation initiation factor 5A-like 1
ELAC2 elaC ribonuclease Z 2
EVI5L ecotropic viral integration site 5-like
EXOSC3 exosome component 3
FADS3 fatty acid desaturase 3
FAM104A family with sequence similarity 104, member A
FAM105A family with sequence similarity 105, member A
FAM111A family with sequence similarity 111, member A
FAM219A family with sequence similarity 219, member A
FAM222B family with sequence similarity 222, member B
FAM78A family with sequence similarity 78, member A
FANCG Fanconi anemia, complementation group G
FBXO32 F-box protein 32
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGD2 FYVE, RhoGEF and PH domain containing 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FHOD1 formin homology 2 domain containing 1
FKBP5 FK506 binding protein 5
FKRP fukutin related protein
FLII flightless I homolog (Drosophila)
FOXD4 forkhead box D4
FOXK2 forkhead box K2
FOXL2 forkhead box L2
FRMD8 FERM domain containing 8
FZD2 frizzled class receptor 2
GAA glucosidase, alpha; acid
GALT galactose-1-phosphate uridylyltransferase
GATA2 GATA binding protein 2
GATSL3 GATS protein-like 3
GEMIN4 gem (nuclear organelle) associated protein 4
GIMAP1 GTPase, IMAP family member 1
GMEB2 glucocorticoid modulatory element binding protein 2
GMPS guanine monphosphate synthase
GNAS-AS1 GNAS antisense RNA 1
GPA33 glycoprotein A33 (transmembrane)
GPR171 G protein-coupled receptor 171
GPR34 G protein-coupled receptor 34
GPR87 G protein-coupled receptor 87
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2H2C GTF2H2 family member C
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
H2AFX H2A histone family, member X
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAVCR2 hepatitis A virus cellular receptor 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HES2 hes family bHLH transcription factor 2
HES4 hes family bHLH transcription factor 4
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HINFP histone H4 transcription factor
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMBS hydroxymethylbilane synthase
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HMHA1 histocompatibility (minor) HA-1
HSF1 heat shock transcription factor 1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
HYAL4 hyaluronoglucosaminidase 4
HYLS1 hydrolethalus syndrome 1
IFI35 interferon-induced protein 35
IFT122 intraflagellar transport 122
IFT74 intraflagellar transport 74
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL15RA interleukin 15 receptor, alpha
IL20RB interleukin 20 receptor beta
IL2RA interleukin 2 receptor, alpha
IL9R interleukin 9 receptor
INPP5K inositol polyphosphate-5-phosphatase K
IRX3 iroquois homeobox 3
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
JAKMIP1 janus kinase and microtubule interacting protein 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCTD12 potassium channel tetramerization domain containing 12
KIAA0020 KIAA0020
KIAA1524 KIAA1524
KIF24 kinesin family member 24
KLHDC7B kelch domain containing 7B
KLHL29 kelch-like family member 29
KLHL9 kelch-like family member 9
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KPNA1 karyopherin alpha 1 (importin alpha 5)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAPTM5 lysosomal protein transmembrane 5
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINGO2 leucine rich repeat and Ig domain containing 2
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC100129550 uncharacterized LOC100129550
LOC100130872 uncharacterized LOC100130872
LOC613037 nuclear pore complex interacting protein pseudogene
LOC90246 uncharacterized LOC90246
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC25 leucine rich repeat containing 25
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP6D1 MAP6 domain containing 1
MBD4 methyl-CpG binding domain protein 4
MCOLN2 mucolipin 2
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough
MELK maternal embryonic leucine zipper kinase
MEN1 multiple endocrine neoplasia I
METTL12 methyltransferase like 12
MINA MYC induced nuclear antigen
MKL1 megakaryoblastic leukemia (translocation) 1
MNDA myeloid cell nuclear differentiation antigen
MOB3B MOB kinase activator 3B
MPLKIP M-phase specific PLK1 interacting protein
MRPL10 mitochondrial ribosomal protein L10
MRPL3 mitochondrial ribosomal protein L3
MRPL47 mitochondrial ribosomal protein L47
MRPS22 mitochondrial ribosomal protein S22
MRRF mitochondrial ribosome recycling factor
MS4A14 membrane-spanning 4-domains, subfamily A, member 14
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MS4A7 membrane-spanning 4-domains, subfamily A, member 7
MTAP methylthioadenosine phosphorylase
MYO1F myosin IF
MYO7A myosin VIIA
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NAGS N-acetylglutamate synthase
NCAPG non-SMC condensin I complex, subunit G
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NELFB negative elongation factor complex member B
NFAM1 NFAT activating protein with ITAM motif 1
NFX1 nuclear transcription factor, X-box binding 1
NIT2 nitrilase family, member 2
NLRC3 NLR family, CARD domain containing 3
NLRC4 NLR family, CARD domain containing 4
NLRP6 NLR family, pyrin domain containing 6
NMT1 N-myristoyltransferase 1
NOL6 nucleolar protein 6 (RNA-associated)
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUP88 nucleoporin 88kDa
NUTM2G NUT family member 2G
NXN nucleoredoxin
OGFR opioid growth factor receptor
OR51Q1 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene)
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR5K1 olfactory receptor, family 5, subfamily K, member 1
OSBPL5 oxysterol binding protein-like 5
PARL presenilin associated, rhomboid-like
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP9 poly (ADP-ribose) polymerase family, member 9
PCED1B PC-esterase domain containing 1B
PER1 period circadian clock 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLAA phospholipase A2-activating protein
PLK1 polo-like kinase 1
PLSCR1 phospholipid scramblase 1
PLXNA1 plexin A1
PNPLA2 patatin-like phospholipase domain containing 2
PNPO pyridoxamine 5'-phosphate oxidase
POC5 POC5 centriolar protein
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PYCRL pyrroline-5-carboxylate reductase-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB38 RAB38, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASL11B RAS-like, family 11, member B
RECQL5 RecQ protein-like 5
RGS18 regulator of G-protein signaling 18
RGS19 regulator of G-protein signaling 19
RIN3 Ras and Rab interactor 3
RNASE6 ribonuclease, RNase A family, k6
RNF26 ring finger protein 26
RNMTL1 RNA methyltransferase like 1
RPL32P3 ribosomal protein L32 pseudogene 3
RPN1 ribophorin I
RRAGA Ras-related GTP binding A
RTN4RL1 reticulon 4 receptor-like 1
RTP5 receptor (chemosensory) transporter protein 5 (putative)
RUVBL1 RuvB-like AAA ATPase 1
SAA1 serum amyloid A1
SAFB scaffold attachment factor B
SAFB2 scaffold attachment factor B2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCML4 sex comb on midleg-like 4 (Drosophila)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SGSH N-sulfoglucosamine sulfohydrolase
SHB Src homology 2 domain containing adaptor protein B
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRPD signal-regulatory protein delta
SIRPG signal-regulatory protein gamma
SLA Src-like-adaptor
SLAMF6 SLAM family member 6
SLAMF8 SLAM family member 8
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A39 solute carrier family 25, member 39
SLC25A51 solute carrier family 25, member 51
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC35G2 solute carrier family 35, member G2
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA71B small nucleolar RNA, H/ACA box 71B
SNX10 sorting nexin 10
SNX4 sorting nexin 4
SOWAHD sosondowah ankyrin repeat domain family member D
SP110 SP110 nuclear body protein
SP140L SP140 nuclear body protein-like
SPATA2 spermatogenesis associated 2
SPATA6L spermatogenesis associated 6-like
SPATS2L spermatogenesis associated, serine-rich 2-like
SPI1 Spi-1 proto-oncogene
STOM stomatin
STOML2 stomatin (EPB72)-like 2
SYBU syntabulin (syntaxin-interacting)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAS2R38 taste receptor, type 2, member 38
TAS2R60 taste receptor, type 2, member 60
TBC1D13 TBC1 domain family, member 13
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX21 T-box 21
TBXAS1 thromboxane A synthase 1 (platelet)
TCN2 transcobalamin II
TFCP2L1 transcription factor CP2-like 1
TFG TRK-fused gene
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR2 toll-like receptor 2
TLR8 toll-like receptor 8
TMCC1 transmembrane and coiled-coil domain family 1
TMEM101 transmembrane protein 101
TMEM259 transmembrane protein 259
TMEM261 transmembrane protein 261
TMIGD2 transmembrane and immunoglobulin domain containing 2
TMPRSS7 transmembrane protease, serine 7
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TNK2 tyrosine kinase, non-receptor, 2
TNS4 tensin 4
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TOR2A torsin family 2, member A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM6 tripartite motif containing 6
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TSC22D3 TSC22 domain family, member 3
TTC7A tetratricopeptide repeat domain 7A
TTC9C tetratricopeptide repeat domain 9C
TXNRD3NB thioredoxin reductase 3 neighbor
TYROBP TYRO protein tyrosine kinase binding protein
UBA5 ubiquitin-like modifier activating enzyme 5
UBAP1 ubiquitin associated protein 1
UBAP2 ubiquitin associated protein 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBQLNL ubiquilin-like
UMPS uridine monophosphate synthetase
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VCP valosin containing protein
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
WDR53 WD repeat domain 53
WDR5B WD repeat domain 5B
WDR81 WD repeat domain 81
ZC3H3 zinc finger CCCH-type containing 3
ZCCHC7 zinc finger, CCHC domain containing 7
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF707 zinc finger protein 707

low expression

Symbol Name
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)