Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

384 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD13 abhydrolase domain containing 13
ABHD17B abhydrolase domain containing 17B
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACAA1 acetyl-CoA acyltransferase 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAMTSL5 ADAMTS-like 5
ADIPOR1 adiponectin receptor 1
ADRB2 adrenoceptor beta 2, surface
AFF4 AF4/FMR2 family, member 4
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGGF1 angiogenic factor with G patch and FHA domains 1
AHCYL2 adenosylhomocysteinase-like 2
AKR1B15 aldo-keto reductase family 1, member B15
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALS2CL ALS2 C-terminal like
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANXA8 annexin A8
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARGLU1 arginine and glutamate rich 1
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL4A ADP-ribosylation factor-like 4A
ARRDC1 arrestin domain containing 1
AVPI1 arginine vasopressin-induced 1
B3GALTL beta 1,3-galactosyltransferase-like
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BICD2 bicaudal D homolog 2 (Drosophila)
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BTF3 basic transcription factor 3
C10ORF67 chromosome 10 open reading frame 67
C10ORF99 chromosome 10 open reading frame 99
C17ORF78 chromosome 17 open reading frame 78
C22ORF23 chromosome 22 open reading frame 23
C5ORF47 chromosome 5 open reading frame 47
C6ORF10 chromosome 6 open reading frame 10
C6ORF25 chromosome 6 open reading frame 25
C9ORF85 chromosome 9 open reading frame 85
CAAP1 caspase activity and apoptosis inhibitor 1
CAPNS2 calpain, small subunit 2
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC120 coiled-coil domain containing 120
CCDC51 coiled-coil domain containing 51
CCDC6 coiled-coil domain containing 6
CDC14B cell division cycle 14B
CDC23 cell division cycle 23
CDC42SE2 CDC42 small effector 2
CDK7 cyclin-dependent kinase 7
CDKN2AIPNL CDKN2A interacting protein N-terminal like
CDR2L cerebellar degeneration-related protein 2-like
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CERS3 ceramide synthase 3
CHMP2B charged multivesicular body protein 2B
CKMT1B creatine kinase, mitochondrial 1B
CNGA1 cyclic nucleotide gated channel alpha 1
CNOT6 CCR4-NOT transcription complex, subunit 6
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CROT carnitine O-octanoyltransferase
CSNK1A1 casein kinase 1, alpha 1
CSNK1G3 casein kinase 1, gamma 3
CTAGE4 CTAGE family, member 4
CTAGE6 CTAGE family, member 6
CTAGE9 CTAGE family, member 9
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CUL1 cullin 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYBRD1 cytochrome b reductase 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DAB2IP DAB2 interacting protein
DCAF10 DDB1 and CUL4 associated factor 10
DCTN4 dynactin 4 (p62)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DISC1 disrupted in schizophrenia 1
DLX3 distal-less homeobox 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DQX1 DEAQ box RNA-dependent ATPase 1
DSG3 desmoglein 3
EBPL emopamil binding protein-like
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EFNA5 ephrin-A5
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ELF1 E74-like factor 1 (ets domain transcription factor)
ELOVL4 ELOVL fatty acid elongase 4
ELOVL7 ELOVL fatty acid elongase 7
EML2 echinoderm microtubule associated protein like 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPGN epithelial mitogen
EPHA1 EPH receptor A1
EQTN equatorin, sperm acrosome associated
ERCC5 excision repair cross-complementation group 5
ERP44 endoplasmic reticulum protein 44
ERRFI1 ERBB receptor feedback inhibitor 1
ETF1 eukaryotic translation termination factor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVI5L ecotropic viral integration site 5-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM126B family with sequence similarity 126, member B
FAM13A-AS1 FAM13A antisense RNA 1
FAM151B family with sequence similarity 151, member B
FAM193B family with sequence similarity 193, member B
FAM213A family with sequence similarity 213, member A
FAM46B family with sequence similarity 46, member B
FAM71C family with sequence similarity 71, member C
FAM89A family with sequence similarity 89, member A
FBXO38 F-box protein 38
FCHSD1 FCH and double SH3 domains 1
FGD4 FYVE, RhoGEF and PH domain containing 4
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GDA guanine deaminase
GFM2 G elongation factor, mitochondrial 2
GHR growth hormone receptor
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLUL glutamate-ammonia ligase
GM2A GM2 ganglioside activator
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPR52 G protein-coupled receptor 52
GPR89B G protein-coupled receptor 89B
GPSM2 G-protein signaling modulator 2
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2IRD1 GTF2I repeat domain containing 1
HARS histidyl-tRNA synthetase
HCCS holocytochrome c synthase
HERPUD2 HERPUD family member 2
HIP1R huntingtin interacting protein 1 related
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HOOK1 hook microtubule-tethering protein 1
HOXC13 homeobox C13
HR hair growth associated
HRK harakiri, BCL2 interacting protein
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HSPA4 heat shock 70kDa protein 4
HSPA4L heat shock 70kDa protein 4-like
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPH1 heat shock 105kDa/110kDa protein 1
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IDI1 isopentenyl-diphosphate delta isomerase 1
IFFO2 intermediate filament family orphan 2
IFNA1 interferon, alpha 1
IFNGR1 interferon gamma receptor 1
IK IK cytokine, down-regulator of HLA II
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IP6K2 inositol hexakisphosphate kinase 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRX2 iroquois homeobox 2
ITM2B integral membrane protein 2B
JAGN1 jagunal homolog 1 (Drosophila)
JMY junction mediating and regulatory protein, p53 cofactor
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KCTD1 potassium channel tetramerization domain containing 1
KCTD9 potassium channel tetramerization domain containing 9
KDSR 3-ketodihydrosphingosine reductase
KLF13 Kruppel-like factor 13
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6C keratin 6C, type II
LARP1 La ribonucleoprotein domain family, member 1
LATS2 large tumor suppressor kinase 2
LIG4 ligase IV, DNA, ATP-dependent
LIPM lipase, family member M
LNX2 ligand of numb-protein X 2
LOC284023 uncharacterized LOC284023
LPAR6 lysophosphatidic acid receptor 6
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MASP2 mannan-binding lectin serine peptidase 2
MBD1 methyl-CpG binding domain protein 1
MBD2 methyl-CpG binding domain protein 2
MCC mutated in colorectal cancers
MED4 mediator complex subunit 4
MEGF9 multiple EGF-like-domains 9
MFSD2A major facilitator superfamily domain containing 2A
MICU2 mitochondrial calcium uptake 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MIPEP mitochondrial intermediate peptidase
MIR17HG miR-17-92 cluster host gene
MIR22HG MIR22 host gene
MOB3B MOB kinase activator 3B
MRPS31 mitochondrial ribosomal protein S31
MRRF mitochondrial ribosome recycling factor
MSH3 mutS homolog 3
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
MT1X metallothionein 1X
MTRF1 mitochondrial translational release factor 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDEL1 nudE neurodevelopment protein 1-like 1
NDFIP2 Nedd4 family interacting protein 2
NEFM neurofilament, medium polypeptide
NFX1 nuclear transcription factor, X-box binding 1
NIPAL4 NIPA-like domain containing 4
NKPD1 NTPase, KAP family P-loop domain containing 1
NLGN4X neuroligin 4, X-linked
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NSG1 neuron specific gene family member 1
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUPL1 nucleoporin like 1
NUTM2G NUT family member 2G
OPTC opticin
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR52N1 olfactory receptor, family 52, subfamily N, member 1
OR56B1 olfactory receptor, family 56, subfamily B, member 1
OR7D2 olfactory receptor, family 7, subfamily D, member 2
OSBPL10 oxysterol binding protein-like 10
OXSR1 oxidative stress responsive 1
PDCD6IP programmed cell death 6 interacting protein
PDS5B PDS5 cohesin associated factor B
PER1 period circadian clock 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGK2 phosphoglycerate kinase 2
PHAX phosphorylated adaptor for RNA export
PHF7 PHD finger protein 7
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIAS1 protein inhibitor of activated STAT, 1
PKP1 plakophilin 1
PLD2 phospholipase D2
PLK2 polo-like kinase 2
PLXDC2 plexin domain containing 2
PNLIPRP3 pancreatic lipase-related protein 3
PNPLA4 patatin-like phospholipase domain containing 4
POF1B premature ovarian failure, 1B
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRO0611 PRO0611 protein
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB5A RAB5A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD17 RAD17 homolog (S. pombe)
RAD21L1 RAD21-like 1 (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RARS arginyl-tRNA synthetase
RASGEF1C RasGEF domain family, member 1C
RB1 retinoblastoma 1
REEP1 receptor accessory protein 1
REXO2 RNA exonuclease 2
RIN1 Ras and Rab interactor 1
RIOK2 RIO kinase 2
RIPK4 receptor-interacting serine-threonine kinase 4
RIPPLY1 ripply transcriptional repressor 1
RNF11 ring finger protein 11
RNF141 ring finger protein 141
S100A7 S100 calcium binding protein A7
S100A7A S100 calcium binding protein A7A
SBDS Shwachman-Bodian-Diamond syndrome
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SECISBP2 SECIS binding protein 2
SEPT10 septin 10
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SFXN1 sideroflexin 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC22A14 solute carrier family 22, member 14
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC35A4 solute carrier family 35, member A4
SLC37A3 solute carrier family 37, member 3
SLC38A9 solute carrier family 38, member 9
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SNORA12 small nucleolar RNA, H/ACA box 12
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA44 small nucleolar RNA, H/ACA box 44
SNORD1C small nucleolar RNA, C/D box 1C
SNRK SNF related kinase
SNX2 sorting nexin 2
SNX24 sorting nexin 24
SOWAHC sosondowah ankyrin repeat domain family member C
SPATA1 spermatogenesis associated 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPOPL speckle-type POZ protein-like
SPRR2G small proline-rich protein 2G
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRP19 signal recognition particle 19kDa
SRSF5 serine/arginine-rich splicing factor 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD4 StAR-related lipid transfer (START) domain containing 4
STK24 serine/threonine kinase 24
STOM stomatin
SUCLG1 succinate-CoA ligase, alpha subunit
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D4 TBC1 domain family, member 4
TCERG1 transcription elongation regulator 1
TDG thymine-DNA glycosylase
TENM1 teneurin transmembrane protein 1
TGFBR1 transforming growth factor, beta receptor 1
THBD thrombomodulin
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
THSD1 thrombospondin, type I, domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM117 transmembrane protein 117
TMEM161B transmembrane protein 161B
TMEM33 transmembrane protein 33
TMEM63B transmembrane protein 63B
TMEM63C transmembrane protein 63C
TMEM74 transmembrane protein 74
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNPO1 transportin 1
TNS4 tensin 4
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPMT thiopurine S-methyltransferase
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM24 tripartite motif containing 24
TRIM35 tripartite motif containing 35
TSHB thyroid stimulating hormone, beta
TUSC1 tumor suppressor candidate 1
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UFM1 ubiquitin-fold modifier 1
UGCG UDP-glucose ceramide glucosyltransferase
UIMC1 ubiquitin interaction motif containing 1
UNC5B unc-5 homolog B (C. elegans)
USP15 ubiquitin specific peptidase 15
USP53 ubiquitin specific peptidase 53
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WBP4 WW domain binding protein 4
WDFY2 WD repeat and FYVE domain containing 2
WDR36 WD repeat domain 36
WDR91 WD repeat domain 91
XG Xg blood group
XIST X inactive specific transcript (non-protein coding)
YIPF1 Yip1 domain family, member 1
YTHDC2 YTH domain containing 2
ZBTB7B zinc finger and BTB domain containing 7B
ZCCHC6 zinc finger, CCHC domain containing 6
ZCCHC7 zinc finger, CCHC domain containing 7
ZCCHC9 zinc finger, CCHC domain containing 9
ZFC3H1 zinc finger, C3H1-type containing
ZNF138 zinc finger protein 138
ZNF277 zinc finger protein 277
ZNF57 zinc finger protein 57

low expression

Symbol Name
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PPP1R10 protein phosphatase 1, regulatory subunit 10
THAP11 THAP domain containing 11
TMEM214 transmembrane protein 214
TP53BP1 tumor protein p53 binding protein 1
USP9X ubiquitin specific peptidase 9, X-linked
ZNF20 zinc finger protein 20
ZNF260 zinc finger protein 260
ZNF616 zinc finger protein 616
ZNF765 zinc finger protein 765
ZNF845 zinc finger protein 845