Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-01A-11R-2132-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

280 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-01A-11R-2132-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACER3 alkaline ceramidase 3
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADRB2 adrenoceptor beta 2, surface
AGFG1 ArfGAP with FG repeats 1
AGTPBP1 ATP/GTP binding protein 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALG8 ALG8, alpha-1,3-glucosyltransferase
AMOTL1 angiomotin like 1
ANAPC15 anaphase promoting complex subunit 15
ANKRD42 ankyrin repeat domain 42
ANLN anillin, actin binding protein
ANO1 anoctamin 1, calcium activated chloride channel
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
APCDD1L adenomatosis polyposis coli down-regulated 1-like
APLN apelin
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP42 Rho GTPase activating protein 42
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASPH aspartate beta-hydroxylase
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATRN attractin
AURKA aurora kinase A
BAIAP2L2 BAI1-associated protein 2-like 2
BIRC2 baculoviral IAP repeat containing 2
BMPR1B bone morphogenetic protein receptor, type IB
BRCA2 breast cancer 2, early onset
C11ORF30 chromosome 11 open reading frame 30
C11ORF73 chromosome 11 open reading frame 73
C2CD3 C2 calcium-dependent domain containing 3
C2CD4C C2 calcium-dependent domain containing 4C
CAB39 calcium binding protein 39
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCDC90B coiled-coil domain containing 90B
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CD3EAP CD3e molecule, epsilon associated protein
CDCA2 cell division cycle associated 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN3 cyclin-dependent kinase inhibitor 3
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPI centromere protein I
CEP295 centrosomal protein 295kDa
CEP57 centrosomal protein 57kDa
CHML choroideremia-like (Rab escort protein 2)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COPS7B COP9 signalosome subunit 7B
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CTH cystathionine gamma-lyase
CTPS1 CTP synthase 1
CTTN cortactin
CWC15 CWC15 spliceosome-associated protein
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CXORF56 chromosome X open reading frame 56
CYB5R4 cytochrome b5 reductase 4
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5
DDIAS DNA damage-induced apoptosis suppressor
DHCR7 7-dehydrocholesterol reductase
DHPS deoxyhypusine synthase
DIAPH3 diaphanous-related formin 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOCK5 dedicator of cytokinesis 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EED embryonic ectoderm development
EFTUD2 elongation factor Tu GTP binding domain containing 2
ENO1 enolase 1, (alpha)
EPRS glutamyl-prolyl-tRNA synthetase
ERICH1 glutamate-rich 1
ESD esterase D
F3 coagulation factor III (thromboplastin, tissue factor)
FAM168A family with sequence similarity 168, member A
FAM188B family with sequence similarity 188, member B
FAT1 FAT atypical cadherin 1
FCHSD2 FCH and double SH3 domains 2
FLNA filamin A, alpha
GAS2L3 growth arrest-specific 2 like 3
GEMIN5 gem (nuclear organelle) associated protein 5
GFI1 growth factor independent 1 transcription repressor
GLA galactosidase, alpha
GNAS-AS1 GNAS antisense RNA 1
GRWD1 glutamate-rich WD repeat containing 1
HES7 hes family bHLH transcription factor 7
HKDC1 hexokinase domain containing 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HPRT1 hypoxanthine phosphoribosyltransferase 1
IARS isoleucyl-tRNA synthetase
INTS4 integrator complex subunit 4
INTS4P1 integrator complex subunit 4 pseudogene 1
INTS4P2 integrator complex subunit 4 pseudogene 2
IPO11 importin 11
JRKL JRK-like
KATNAL1 katanin p60 subunit A-like 1
KCTD21 potassium channel tetramerization domain containing 21
KIF14 kinesin family member 14
KLK5 kallikrein-related peptidase 5
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT5 keratin 5, type II
KYNU kynureninase
LDHA lactate dehydrogenase A
LOC284788 uncharacterized LOC284788
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC59 leucine rich repeat containing 59
LRRN4 leucine rich repeat neuronal 4
MAP2 microtubule-associated protein 2
MAP7D3 MAP7 domain containing 3
MCM10 minichromosome maintenance complex component 10
MFN2 mitofusin 2
MICB MHC class I polypeptide-related sequence B
MIER2 mesoderm induction early response 1, family member 2
MMGT1 membrane magnesium transporter 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRPL48 mitochondrial ribosomal protein L48
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTMR2 myotubularin related protein 2
MYADM myeloid-associated differentiation marker
MYEOV myeloma overexpressed
MYO1B myosin IB
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NADSYN1 NAD synthetase 1
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NCAPG non-SMC condensin I complex, subunit G
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCF2 neutrophil cytosolic factor 2
NCL nucleolin
NDC1 NDC1 transmembrane nucleoporin
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEU3 sialidase 3 (membrane sialidase)
NHEJ1 nonhomologous end-joining factor 1
NIPAL3 NIPA-like domain containing 3
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKRF NFKB repressing factor
NLE1 notchless homolog 1 (Drosophila)
NOL8 nucleolar protein 8
NQO1 NAD(P)H dehydrogenase, quinone 1
NRG1 neuregulin 1
NUMA1 nuclear mitotic apparatus protein 1
NUP62CL nucleoporin 62kDa C-terminal like
NXN nucleoredoxin
OCRL oculocerebrorenal syndrome of Lowe
OR6K3 olfactory receptor, family 6, subfamily K, member 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAAF1 proteasomal ATPase-associated factor 1
PABPC4L poly(A) binding protein, cytoplasmic 4-like
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PANX1 pannexin 1
PCDHGA1 protocadherin gamma subfamily A, 1
PDS5B PDS5 cohesin associated factor B
PFKP phosphofructokinase, platelet
PICALM phosphatidylinositol binding clathrin assembly protein
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLS3 plastin 3
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPME1 protein phosphatase methylesterase 1
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PTGR1 prostaglandin reductase 1
RAB30 RAB30, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RBM19 RNA binding motif protein 19
RBM28 RNA binding motif protein 28
RELT RELT tumor necrosis factor receptor
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RND3 Rho family GTPase 3
RNF121 ring finger protein 121
RNF169 ring finger protein 169
RPL36A ribosomal protein L36a
RPL7 ribosomal protein L7
RPS3 ribosomal protein S3
RSF1 remodeling and spacing factor 1
SAPCD2 suppressor APC domain containing 2
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SET SET nuclear proto-oncogene
SFTA1P surfactant associated 1, pseudogene
SGOL2 shugoshin-like 2 (S. pombe)
SH2D3A SH2 domain containing 3A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SKA3 spindle and kinetochore associated complex subunit 3
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A43 solute carrier family 25, member 43
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC43A3 solute carrier family 43, member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC2 structural maintenance of chromosomes 2
SND1 staphylococcal nuclease and tudor domain containing 1
SPANXA2 SPANX family, member A2
SPANXB1 SPANX family, member B1
SPANXC SPANX family, member C
SPANXD SPANX family, member D
SPATA5 spermatogenesis associated 5
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPIN4 spindlin family, member 4
SPRYD7 SPRY domain containing 7
SRP72 signal recognition particle 72kDa
SRXN1 sulfiredoxin 1
SSRP1 structure specific recognition protein 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST7-OT3 ST7 overlapping transcript 3
STC2 stanniocalcin 2
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TALDO1 transaldolase 1
TENM4 teneurin transmembrane protein 4
THBD thrombomodulin
TIGD2 tigger transposable element derived 2
TLK1 tousled-like kinase 1
TMEM123 transmembrane protein 123
TMEM126A transmembrane protein 126A
TMEM126B transmembrane protein 126B
TMEM206 transmembrane protein 206
TMEM255A transmembrane protein 255A
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TRAF3IP2 TRAF3 interacting protein 2
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM36 tripartite motif containing 36
TSKU tsukushi, small leucine rich proteoglycan
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
TTK TTK protein kinase
TXN thioredoxin
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TXNRD1 thioredoxin reductase 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UVRAG UV radiation resistance associated
VAMP7 vesicle-associated membrane protein 7
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR77 WD repeat domain 77
XKR6 XK, Kell blood group complex subunit-related family, member 6
XRRA1 X-ray radiation resistance associated 1
YAP1 Yes-associated protein 1
YARS tyrosyl-tRNA synthetase
ZBTB2 zinc finger and BTB domain containing 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC9 zinc finger, DHHC-type containing 9
ZNF114 zinc finger protein 114

low expression

Symbol Name
BIVM basic, immunoglobulin-like variable motif containing
C2ORF42 chromosome 2 open reading frame 42
CCNJ cyclin J
FBXO11 F-box protein 11
NRBP1 nuclear receptor binding protein 1
PDCD7 programmed cell death 7
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PRKD3 protein kinase D3
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RNF103 ring finger protein 103
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SNX1 sorting nexin 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TM2D3 TM2 domain containing 3