Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

401 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACER2 alkaline ceramidase 2
ACLY ATP citrate lyase
ACRC acidic repeat containing
ADAP2 ArfGAP with dual PH domains 2
ADNP2 ADNP homeobox 2
AK3 adenylate kinase 3
AKNAD1 AKNA domain containing 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRD31 ankyrin repeat domain 31
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APEH acylaminoacyl-peptide hydrolase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL17B ADP-ribosylation factor-like 17B
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASPRV1 aspartic peptidase, retroviral-like 1
ASTL astacin-like metallo-endopeptidase (M12 family)
ATP11C ATPase, class VI, type 11C
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATXN7L3 ataxin 7-like 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BPIFC BPI fold containing family C
C10ORF76 chromosome 10 open reading frame 76
C10ORF99 chromosome 10 open reading frame 99
C1ORF210 chromosome 1 open reading frame 210
C2ORF16 chromosome 2 open reading frame 16
C6ORF223 chromosome 6 open reading frame 223
C9ORF131 chromosome 9 open reading frame 131
CALB2 calbindin 2
CALCR calcitonin receptor
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBWD1 COBW domain containing 1
CBWD3 COBW domain containing 3
CCDC171 coiled-coil domain containing 171
CD2AP CD2-associated protein
CDC25B cell division cycle 25B
CDC37L1 cell division cycle 37-like 1
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDSN corneodesmosin
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CLCA2 chloride channel accessory 2
CLDN17 claudin 17
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLTA clathrin, light chain A
CNGB3 cyclic nucleotide gated channel beta 3
CNOT6 CCR4-NOT transcription complex, subunit 6
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTLN centlein, centrosomal protein
CPEB2 cytoplasmic polyadenylation element binding protein 2
CSNK1A1 casein kinase 1, alpha 1
CTNS cystinosin, lysosomal cystine transporter
CTSL3P cathepsin L family member 3, pseudogene
CXORF40B chromosome X open reading frame 40B
CXXC1 CXXC finger protein 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCAF10 DDB1 and CUL4 associated factor 10
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND2D DENN/MADD domain containing 2D
DENND4C DENN/MADD domain containing 4C
DENND6A DENN/MADD domain containing 6A
DHCR24 24-dehydrocholesterol reductase
DLX3 distal-less homeobox 3
DOCK6 dedicator of cytokinesis 6
DOCK8 dedicator of cytokinesis 8
DSC2 desmocollin 2
DSG1 desmoglein 1
DSG3 desmoglein 3
DSP desmoplakin
EAF1 ELL associated factor 1
EDA2R ectodysplasin A2 receptor
EDDM3B epididymal protein 3B
EFR3B EFR3 homolog B (S. cerevisiae)
ELL2 elongation factor, RNA polymerase II, 2
ELOVL4 ELOVL fatty acid elongase 4
ELOVL6 ELOVL fatty acid elongase 6
ENAH enabled homolog (Drosophila)
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPGN epithelial mitogen
EPPK1 epiplakin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPT1 ethanolaminephosphotransferase 1
EREG epiregulin
ESRP2 epithelial splicing regulatory protein 2
EXOC8 exocyst complex component 8
EXOSC3 exosome component 3
FAM122C family with sequence similarity 122C
FAM155B family with sequence similarity 155, member B
FAM199X family with sequence similarity 199, X-linked
FAM205BP transmembrane protein C9orf144B pseudogene
FAM213A family with sequence similarity 213, member A
FAM214B family with sequence similarity 214, member B
FAM46B family with sequence similarity 46, member B
FAM58BP cyclin-related protein FAM58B
FAM83G family with sequence similarity 83, member G
FANCG Fanconi anemia, complementation group G
FBXO46 F-box protein 46
FBXO48 F-box protein 48
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FEM1C fem-1 homolog c (C. elegans)
FFAR2 free fatty acid receptor 2
FLJ44635 TPT1-like protein
FMNL2 formin-like 2
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FREM1 FRAS1 related extracellular matrix 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB1 GRB2-associated binding protein 1
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GALT galactose-1-phosphate uridylyltransferase
GBA2 glucosidase, beta (bile acid) 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GGT8P gamma-glutamyltransferase 8 pseudogene
GHITM growth hormone inducible transmembrane protein
GLIPR2 GLI pathogenesis-related 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GTSF1 gametocyte specific factor 1
HAUS6 HAUS augmin-like complex, subunit 6
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HOOK1 hook microtubule-tethering protein 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
IDS iduronate 2-sulfatase
IFFO2 intermediate filament family orphan 2
IFITM4P interferon induced transmembrane protein 4 pseudogene
IFNA8 interferon, alpha 8
IGBP1 immunoglobulin (CD79A) binding protein 1
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IGSF3 immunoglobulin superfamily, member 3
IL13RA1 interleukin 13 receptor, alpha 1
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
INADL InaD-like (Drosophila)
INSIG1 insulin induced gene 1
INTS4P2 integrator complex subunit 4 pseudogene 2
IQCF1 IQ motif containing F1
IREB2 iron-responsive element binding protein 2
JAK2 Janus kinase 2
KANK1 KN motif and ankyrin repeat domains 1
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KDM4C lysine (K)-specific demethylase 4C
KGFLP1 fibroblast growth factor 7 pseudogene
KHNYN KH and NYN domain containing
KIAA0020 KIAA0020
KIAA1551 KIAA1551
KIAA2026 KIAA2026
KIF5B kinesin family member 5B
KLF3 Kruppel-like factor 3 (basic)
KRT2 keratin 2, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRT80 keratin 80, type II
LAD1 ladinin 1
LAMP2 lysosomal-associated membrane protein 2
LCE3E late cornified envelope 3E
LDLR low density lipoprotein receptor
LINC00174 long intergenic non-protein coding RNA 174
LIPG lipase, endothelial
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene
LOC389705 chromosome 4 open reading frame 27 pseudogene
LPAR3 lysophosphatidic acid receptor 3
LSM11 LSM11, U7 small nuclear RNA associated
LTB4R leukotriene B4 receptor
MACF1 microtubule-actin crosslinking factor 1
MAGEA1 melanoma antigen family A1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MALT1 MALT1 paracaspase
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAT2A methionine adenosyltransferase II, alpha
MBD1 methyl-CpG binding domain protein 1
MBNL3 muscleblind-like splicing regulator 3
MED18 mediator complex subunit 18
MED8 mediator complex subunit 8
MELK maternal embryonic leucine zipper kinase
MINK1 misshapen-like kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MORC3 MORC family CW-type zinc finger 3
MORC4 MORC family CW-type zinc finger 4
MOSPD1 motile sperm domain containing 1
MPZL2 myelin protein zero-like 2
MRGPRX4 MAS-related GPR, member X4
MSMO1 methylsterol monooxygenase 1
MTF1 metal-regulatory transcription factor 1
MTM1 myotubularin 1
MVK mevalonate kinase
MYBPHL myosin binding protein H-like
MYO1C myosin IC
NELL2 NEL-like 2 (chicken)
NKPD1 NTPase, KAP family P-loop domain containing 1
NKRF NFKB repressing factor
NMI N-myc (and STAT) interactor
NPEPPS aminopeptidase puromycin sensitive
NRBF2 nuclear receptor binding factor 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSG1 neuron specific gene family member 1
NT5C2 5'-nucleotidase, cytosolic II
NWD2 NACHT and WD repeat domain containing 2
NXF1 nuclear RNA export factor 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCLN occludin
OCM2 oncomodulin 2
OR10G2 olfactory receptor, family 10, subfamily G, member 2
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2M2 olfactory receptor, family 2, subfamily M, member 2
OR52H1 olfactory receptor, family 52, subfamily H, member 1
OR5K2 olfactory receptor, family 5, subfamily K, member 2
OVCH1 ovochymase 1
OVOL1 ovo-like zinc finger 1
OXSR1 oxidative stress responsive 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAQR5 progestin and adipoQ receptor family member V
PBDC1 polysaccharide biosynthesis domain containing 1
PCYOX1L prenylcysteine oxidase 1 like
PDCD6IP programmed cell death 6 interacting protein
PDZD11 PDZ domain containing 11
PEA15 phosphoprotein enriched in astrocytes 15
PGK1 phosphoglycerate kinase 1
PHF6 PHD finger protein 6
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PLA2G3 phospholipase A2, group III
PLA2G4D phospholipase A2, group IVD (cytosolic)
PLA2G4E phospholipase A2, group IVE
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLIN3 perilipin 3
PLS3 plastin 3
PLSCR3 phospholipid scramblase 3
POF1B premature ovarian failure, 1B
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU3F1 POU class 3 homeobox 1
PP2D1 protein phosphatase 2C-like domain containing 1
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP1R21 protein phosphatase 1, regulatory subunit 21
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPRD protein tyrosine phosphatase, receptor type, D
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB25 RAB25, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RANBP6 RAN binding protein 6
RAP2C RAP2C, member of RAS oncogene family
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RBM41 RNA binding motif protein 41
RCL1 RNA terminal phosphate cyclase-like 1
REXO2 RNA exonuclease 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIC1 RAB6A GEF complex partner 1
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF11 ring finger protein 11
RNF38 ring finger protein 38
RNF39 ring finger protein 39
RPL22L1 ribosomal protein L22-like 1
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPTN repetin
RRAGA Ras-related GTP binding A
RTN1 reticulon 1
RUFY2 RUN and FYVE domain containing 2
RUSC1 RUN and SH3 domain containing 1
RYBP RING1 and YY1 binding protein
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SESN1 sestrin 1
SGK223 homolog of rat pragma of Rnd2
SH3RF2 SH3 domain containing ring finger 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHB Src homology 2 domain containing adaptor protein B
SLC10A3 solute carrier family 10, member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC22A23 solute carrier family 22, member 23
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC25A30 solute carrier family 25, member 30
SLC25A43 solute carrier family 25, member 43
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A51 solute carrier family 25, member 51
SLC25A52 solute carrier family 25, member 52
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC38A2 solute carrier family 38, member 2
SLC38A9 solute carrier family 38, member 9
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLMAP sarcolemma associated protein
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SOWAHC sosondowah ankyrin repeat domain family member C
SPATA6L spermatogenesis associated 6-like
SPIN4 spindlin family, member 4
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPOPL speckle-type POZ protein-like
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2G small proline-rich protein 2G
SQLE squalene epoxidase
STAG2 stromal antigen 2
STOML2 stomatin (EPB72)-like 2
STPG2 sperm-tail PG-rich repeat containing 2
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAS2R38 taste receptor, type 2, member 38
TCAF2 TRPM8 channel-associated factor 2
TESK2 testis-specific kinase 2
THEM5 thioesterase superfamily member 5
THOC2 THO complex 2
TLDC1 TBC/LysM-associated domain containing 1
TMC1 transmembrane channel-like 1
TMEM154 transmembrane protein 154
TMEM164 transmembrane protein 164
TMEM167A transmembrane protein 167A
TMEM185A transmembrane protein 185A
TMEM86A transmembrane protein 86A
TMPRSS13 transmembrane protease, serine 13
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOPAZ1 testis and ovary specific PAZ domain containing 1
TPK1 thiamin pyrophosphokinase 1
TRIM6 tripartite motif containing 6
TRIML1 tripartite motif family-like 1
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TTC39B tetratricopeptide repeat domain 39B
TUBB8 tubulin, beta 8 class VIII
TWF1 twinfilin actin binding protein 1
UBE3C ubiquitin protein ligase E3C
UBXN8 UBX domain protein 8
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UNC13B unc-13 homolog B (C. elegans)
USP38 ubiquitin specific peptidase 38
VAMP7 vesicle-associated membrane protein 7
VCP valosin containing protein
VIPR1 vasoactive intestinal peptide receptor 1
VLDLR very low density lipoprotein receptor
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
VSIG1 V-set and immunoglobulin domain containing 1
VSIG10L V-set and immunoglobulin domain containing 10 like
WDR37 WD repeat domain 37
WDR44 WD repeat domain 44
WDR47 WD repeat domain 47
WDR55 WD repeat domain 55
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XKR6 XK, Kell blood group complex subunit-related family, member 6
YIPF6 Yip1 domain family, member 6
ZBTB33 zinc finger and BTB domain containing 33
ZBTB5 zinc finger and BTB domain containing 5
ZBTB6 zinc finger and BTB domain containing 6
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZCCHC7 zinc finger, CCHC domain containing 7
ZDHHC21 zinc finger, DHHC-type containing 21
ZNF107 zinc finger protein 107
ZNF200 zinc finger protein 200
ZNF319 zinc finger protein 319
ZNF526 zinc finger protein 526
ZNF57 zinc finger protein 57
ZNF586 zinc finger protein 586
ZNF654 zinc finger protein 654
ZNF770 zinc finger protein 770
ZNF823 zinc finger protein 823
ZSWIM5 zinc finger, SWIM-type containing 5

low expression

Symbol Name
CDK11B cyclin-dependent kinase 11B
PEX10 peroxisomal biogenesis factor 10
SETD6 SET domain containing 6
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa