Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

386 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ACR acrosin
ACTB actin, beta
ACTG1 actin gamma 1
ADAMTSL5 ADAMTS-like 5
ADAP2 ArfGAP with dual PH domains 2
ADGRF2 adhesion G protein-coupled receptor F2
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AGPAT4-IT1 AGPAT4 intronic transcript 1
AIM1L absent in melanoma 1-like
AKIRIN2 akirin 2
ALAS1 5'-aminolevulinate synthase 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALOX12 arachidonate 12-lipoxygenase
AMD1 adenosylmethionine decarboxylase 1
AMOTL2 angiomotin like 2
ANKRD22 ankyrin repeat domain 22
ANKRD35 ankyrin repeat domain 35
ANXA1 annexin A1
ANXA2P3 annexin A2 pseudogene 3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APLF aprataxin and PNKP like factor
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARF6 ADP-ribosylation factor 6
ARHGAP20 Rho GTPase activating protein 20
ARHGAP23 Rho GTPase activating protein 23
ATP11AUN ATP11A upstream neighbor
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BARX2 BARX homeobox 2
BCL10 B-cell CLL/lymphoma 10
BCL3 B-cell CLL/lymphoma 3
BDKRB1 bradykinin receptor B1
BLNK B-cell linker
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
C1ORF116 chromosome 1 open reading frame 116
C2CD2L C2CD2-like
C2ORF54 chromosome 2 open reading frame 54
C6ORF132 chromosome 6 open reading frame 132
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN2 calpain 2, (m/II) large subunit
CARD10 caspase recruitment domain family, member 10
CCDC120 coiled-coil domain containing 120
CCDC27 coiled-coil domain containing 27
CDA cytidine deaminase
CDCP1 CUB domain containing protein 1
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CES2 carboxylesterase 2
CKMT1A creatine kinase, mitochondrial 1A
CLDN4 claudin 4
CLIC3 chloride intracellular channel 3
CLUH clustered mitochondria (cluA/CLU1) homolog
CNN2 calponin 2
CRB3 crumbs family member 3
CRCT1 cysteine-rich C-terminal 1
CRNN cornulin
CSNK1A1L casein kinase 1, alpha 1-like
CSRNP1 cysteine-serine-rich nuclear protein 1
CSRP1 cysteine and glycine-rich protein 1
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCP1A decapping mRNA 1A
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DENND6A DENN/MADD domain containing 6A
DHRS1 dehydrogenase/reductase (SDR family) member 1
DIAPH1 diaphanous-related formin 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DKFZP434L192 uncharacterized protein DKFZp434L192
DOK4 docking protein 4
DOT1L DOT1-like histone H3K79 methyltransferase
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DSG3 desmoglein 3
DUOX1 dual oxidase 1
DUOXA1 dual oxidase maturation factor 1
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DYNAP dynactin associated protein
ECHDC3 enoyl CoA hydratase domain containing 3
EEA1 early endosome antigen 1
EHD4 EH-domain containing 4
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ELL3 elongation factor RNA polymerase II-like 3
ELOVL1 ELOVL fatty acid elongase 1
EML2 echinoderm microtubule associated protein like 2
ENDOU endonuclease, polyU-specific
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
EPS8L2 EPS8-like 2
ERRFI1 ERBB receptor feedback inhibitor 1
ESRP2 epithelial splicing regulatory protein 2
ETF1 eukaryotic translation termination factor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVA1C eva-1 homolog C (C. elegans)
EVPL envoplakin
EZR ezrin
FAM129B family with sequence similarity 129, member B
FAM160A2 family with sequence similarity 160, member A2
FAM46B family with sequence similarity 46, member B
FAM71A family with sequence similarity 71, member A
FAM74A3 family with sequence similarity 74, member A3
FAM83C family with sequence similarity 83, member C
FANCD2OS FANCD2 opposite strand
FAR1 fatty acyl CoA reductase 1
FBRS fibrosin
FBXO46 F-box protein 46
FEM1B fem-1 homolog b (C. elegans)
FGFBP1 fibroblast growth factor binding protein 1
FLJ44635 TPT1-like protein
FOSL1 FOS-like antigen 1
GARS glycyl-tRNA synthetase
GAS7 growth arrest-specific 7
GBP6 guanylate binding protein family, member 6
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GH1 growth hormone 1
GIPC1 GIPC PDZ domain containing family, member 1
GJB5 gap junction protein, beta 5, 31.1kDa
GMPPB GDP-mannose pyrophosphorylase B
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPX3 glutathione peroxidase 3
GRHL3 grainyhead-like 3 (Drosophila)
GRK6 G protein-coupled receptor kinase 6
GSPT1 G1 to S phase transition 1
HARS histidyl-tRNA synthetase
HBEGF heparin-binding EGF-like growth factor
HCG22 HLA complex group 22
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOPX HOP homeobox
HPCAL1 hippocalcin-like 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA4L heat shock 70kDa protein 4-like
HSPB8 heat shock 22kDa protein 8
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFFO2 intermediate filament family orphan 2
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL20 interleukin 20
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITPKC inositol-trisphosphate 3-kinase C
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
IVL involucrin
KALRN kalirin, RhoGEF kinase
KAZN kazrin, periplakin interacting protein
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCTD10 potassium channel tetramerization domain containing 10
KDM6B lysine (K)-specific demethylase 6B
KDM7A lysine (K)-specific demethylase 7A
KIAA1191 KIAA1191
KIAA1468 KIAA1468
KLF16 Kruppel-like factor 16
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLHL18 kelch-like family member 18
KLK11 kallikrein-related peptidase 11
KLK12 kallikrein-related peptidase 12
KLK13 kallikrein-related peptidase 13
KRT13 keratin 13, type I
KRT4 keratin 4, type II
KRT6A keratin 6A, type II
KRT6C keratin 6C, type II
LAMB4 laminin, beta 4
LARP1B La ribonucleoprotein domain family, member 1B
LARP4B La ribonucleoprotein domain family, member 4B
LDLR low density lipoprotein receptor
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS9B lectin, galactoside-binding, soluble, 9B
LINC00312 long intergenic non-protein coding RNA 312
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LMNA lamin A/C
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC643387 TAR DNA binding protein pseudogene
LOC644936 actin, beta pseudogene
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRRC7 leucine rich repeat containing 7
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LTB4R leukotriene B4 receptor
LUZP2 leucine zipper protein 2
LYPD3 LY6/PLAUR domain containing 3
MALL mal, T-cell differentiation protein-like
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP7D1 MAP7 domain containing 1
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST4 microtubule associated serine/threonine kinase family member 4
MAT2A methionine adenosyltransferase II, alpha
MESDC1 mesoderm development candidate 1
MGLL monoglyceride lipase
MIDN midnolin
MIMT1 MER1 repeat containing imprinted transcript 1 (non-protein coding)
MIPEP mitochondrial intermediate peptidase
MNT MAX network transcriptional repressor
MON1A MON1 secretory trafficking family member A
MPZL2 myelin protein zero-like 2
MTM1 myotubularin 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYO1E myosin IE
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NBEAL2 neurobeachin-like 2
NDEL1 nudE neurodevelopment protein 1-like 1
NET1 neuroepithelial cell transforming 1
NKX2-8 NK2 homeobox 8
NNAT neuronatin
NOP14 NOP14 nucleolar protein
NOP16 NOP16 nucleolar protein
NPEPPS aminopeptidase puromycin sensitive
NRADDP neurotrophin receptor associated death domain, pseudogene
NUAK2 NUAK family, SNF1-like kinase, 2
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR2G2 olfactory receptor, family 2, subfamily G, member 2
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)
OTOP2 otopetrin 2
OTOP3 otopetrin 3
OXSR1 oxidative stress responsive 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PA2G4 proliferation-associated 2G4, 38kDa
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PAOX polyamine oxidase (exo-N4-amino)
PAX9 paired box 9
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE12 phosphodiesterase 12
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM5 PDZ and LIM domain 5
PDZRN3 PDZ domain containing ring finger 3
PEG3 paternally expressed 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDB3 pleckstrin homology-like domain, family B, member 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITX1 paired-like homeodomain 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PLA2G3 phospholipase A2, group III
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLIN3 perilipin 3
PLK3 polo-like kinase 3
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
POU2F3 POU class 2 homeobox 3
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPL periplakin
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCD protein kinase C, delta
PRSS27 protease, serine 27
PRSS3 protease, serine, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTPRE protein tyrosine phosphatase, receptor type, E
RAB11A RAB11A, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAET1E retinoic acid early transcript 1E
RAET1L retinoic acid early transcript 1L
RALGDS ral guanine nucleotide dissociation stimulator
RCOR1 REST corepressor 1
RGS12 regulator of G-protein signaling 12
RND3 Rho family GTPase 3
RNF126P1 ring finger protein 126 pseudogene 1
RPL29P2 ribosomal protein L29 pseudogene 2
RRAD Ras-related associated with diabetes
RREB1 ras responsive element binding protein 1
S100A11 S100 calcium binding protein A11
S100A14 S100 calcium binding protein A14
S100A16 S100 calcium binding protein A16
S100A8 S100 calcium binding protein A8
SAMD5 sterile alpha motif domain containing 5
SARS seryl-tRNA synthetase
SBSN suprabasin
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SESN2 sestrin 2
SF1 splicing factor 1
SHB Src homology 2 domain containing adaptor protein B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIK1 salt-inducible kinase 1
SLAIN2 SLAIN motif family, member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD3 SMAD family member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNRK SNF related kinase
SOWAHC sosondowah ankyrin repeat domain family member C
SOX9 SRY (sex determining region Y)-box 9
SPACA4 sperm acrosome associated 4
SPAG11A sperm associated antigen 11A
SPDL1 spindle apparatus coiled-coil protein 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
SPRR2A small proline-rich protein 2A
SPRR2C small proline-rich protein 2C (pseudogene)
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR3 small proline-rich protein 3
SREK1IP1 SREK1-interacting protein 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF2 serine/arginine-rich splicing factor 2
STK40 serine/threonine kinase 40
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACSTD2 tumor-associated calcium signal transducer 2
TEC tec protein tyrosine kinase
TGM1 transglutaminase 1
TGM3 transglutaminase 3
THSD4 thrombospondin, type I, domain containing 4
TIAM1 T-cell lymphoma invasion and metastasis 1
TICAM1 toll-like receptor adaptor molecule 1
TJP1 tight junction protein 1
TLX1 T-cell leukemia homeobox 1
TLX1NB TLX1 neighbor
TM4SF1 transmembrane 4 L six family member 1
TMEM132C transmembrane protein 132C
TMEM217 transmembrane protein 217
TMEM253 transmembrane protein 253
TMEM40 transmembrane protein 40
TMEM45B transmembrane protein 45B
TMEM79 transmembrane protein 79
TMEM9B TMEM9 domain family, member B
TMPRSS11D transmembrane protease, serine 11D
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM4 tropomyosin 4
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
TRIP10 thyroid hormone receptor interactor 10
TUBB2A tubulin, beta 2A class IIa
TUBB4B tubulin, beta 4B class IVb
TYRO3 TYRO3 protein tyrosine kinase
USH1G Usher syndrome 1G (autosomal recessive)
USP6NL USP6 N-terminal like
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR1 WD repeat domain 1
WDR43 WD repeat domain 43
WDR55 WD repeat domain 55
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBTB7A zinc finger and BTB domain containing 7A
ZBTB7B zinc finger and BTB domain containing 7B
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZIM2 zinc finger, imprinted 2
ZNF185 zinc finger protein 185 (LIM domain)
ZNF219 zinc finger protein 219
ZNF584 zinc finger protein 584
ZNF750 zinc finger protein 750
ZRANB1 zinc finger, RAN-binding domain containing 1
ZYX zyxin

low expression

Symbol Name
C1ORF216 chromosome 1 open reading frame 216
SKAP2 src kinase associated phosphoprotein 2