Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

422 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABR active BCR-related
ADAM28 ADAM metallopeptidase domain 28
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD20A4 ankyrin repeat domain 20 family, member A4
ANXA11 annexin A11
ANXA2P3 annexin A2 pseudogene 3
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
AREG amphiregulin
ARG2 arginase 2
ARL5B ADP-ribosylation factor-like 5B
ARSD arylsulfatase D
ARSF arylsulfatase F
ASCL3 achaete-scute family bHLH transcription factor 3
ATF3 activating transcription factor 3
ATP10B ATPase, class V, type 10B
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP9A ATPase, class II, type 9A
ATXN7 ataxin 7
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BARX2 BARX homeobox 2
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL10 B-cell CLL/lymphoma 10
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BMP3 bone morphogenetic protein 3
BTG2 BTG family, member 2
C15ORF39 chromosome 15 open reading frame 39
C4ORF45 chromosome 4 open reading frame 45
C9ORF57 chromosome 9 open reading frame 57
CAB39L calcium binding protein 39-like
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPN2 calpain 2, (m/II) large subunit
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNL1 cyclin L1
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH22 cadherin 22, type 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLCA4 chloride channel accessory 4
CLCF1 cardiotrophin-like cytokine factor 1
CLDN23 claudin 23
CLDN25 claudin 25
CLDN4 claudin 4
CLDN7 claudin 7
CLIC6 chloride intracellular channel 6
CLINT1 clathrin interactor 1
CLMN calmin (calponin-like, transmembrane)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CPA3 carboxypeptidase A3 (mast cell)
CPA4 carboxypeptidase A4
CPD carboxypeptidase D
CROT carnitine O-octanoyltransferase
CSRNP1 cysteine-serine-rich nuclear protein 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTAGE5 CTAGE family, member 5
CTGF connective tissue growth factor
CUEDC1 CUE domain containing 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL6 chemokine (C-X-C motif) ligand 6
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
DACH1 dachshund family transcription factor 1
DAGLA diacylglycerol lipase, alpha
DAPK1 death-associated protein kinase 1
DCP1A decapping mRNA 1A
DCT dopachrome tautomerase
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLG2 discs, large homolog 2 (Drosophila)
DLL1 delta-like 1 (Drosophila)
DOC2B double C2-like domains, beta
DPYSL4 dihydropyrimidinase-like 4
DTWD2 DTW domain containing 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUOX2 dual oxidase 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDN1 endothelin 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EHF ets homologous factor
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA2 EPH receptor A2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV3 ets variant 3
EYA2 EYA transcriptional coactivator and phosphatase 2
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
FAM13B family with sequence similarity 13, member B
FAM160A2 family with sequence similarity 160, member A2
FAM53C family with sequence similarity 53, member C
FAM71A family with sequence similarity 71, member A
FAM84B family with sequence similarity 84, member B
FAR1 fatty acyl CoA reductase 1
FASTKD1 FAST kinase domains 1
FBF1 Fas (TNFRSF6) binding factor 1
FBXO33 F-box protein 33
FBXO34 F-box protein 34
FERD3L Fer3-like bHLH transcription factor
FGF1 fibroblast growth factor 1 (acidic)
FLJ13224 uncharacterized LOC79857
FLJ44635 TPT1-like protein
FMO1 flavin containing monooxygenase 1
FMO4 flavin containing monooxygenase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXI1 forkhead box I1
FOXO1 forkhead box O1
FOXQ1 forkhead box Q1
FRMD4B FERM domain containing 4B
FUT2 fucosyltransferase 2 (secretor status included)
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GATA2 GATA binding protein 2
GATA6 GATA binding protein 6
GCSAML germinal center-associated, signaling and motility-like
GK glycerol kinase
GLUL glutamate-ammonia ligase
GMDS GDP-mannose 4,6-dehydratase
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GOLGA2P3Y golgin A2 pseudogene 3, Y-linked
GPR3 G protein-coupled receptor 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPRC6A G protein-coupled receptor, class C, group 6, member A
GREM2 gremlin 2, DAN family BMP antagonist
GSR glutathione reductase
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1
HBEGF heparin-binding EGF-like growth factor
HEPACAM2 HEPACAM family member 2
HIST1H4L histone cluster 1, H4l
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IER3 immediate early response 3
IFFO2 intermediate filament family orphan 2
IFNA8 interferon, alpha 8
IKZF2 IKAROS family zinc finger 2 (Helios)
IL17A interleukin 17A
IL17F interleukin 17F
IL19 interleukin 19
IL20 interleukin 20
IL22 interleukin 22
IL26 interleukin 26
IL33 interleukin 33
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRS2 insulin receptor substrate 2
IRX3 iroquois homeobox 3
IRX5 iroquois homeobox 5
ITPKC inositol-trisphosphate 3-kinase C
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
JDP2 Jun dimerization protein 2
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM6B lysine (K)-specific demethylase 6B
KIAA0754 KIAA0754
KIAA1217 KIAA1217
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLF6 Kruppel-like factor 6
KLHL15 kelch-like family member 15
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRT23 keratin 23, type I
LBX1 ladybird homeobox 1
LCA5 Leber congenital amaurosis 5
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LINC01587 long intergenic non-protein coding RNA 1587
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100133050 glucuronidase, beta pseudogene
LOC283070
LOC642929 general transcription factor II, i pseudogene
LOC647859 occludin pseudogene
LONRF1 LON peptidase N-terminal domain and ring finger 1
LRG1 leucine-rich alpha-2-glycoprotein 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRK2 leucine-rich repeat kinase 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAT2A methionine adenosyltransferase II, alpha
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MFSD7 major facilitator superfamily domain containing 7
MIDN midnolin
MIR22HG MIR22 host gene
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MNT MAX network transcriptional repressor
MORC3 MORC family CW-type zinc finger 3
MPPED2 metallophosphoesterase domain containing 2
MPV17L MPV17 mitochondrial membrane protein-like
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
N4BP2L2 NEDD4 binding protein 2-like 2
NCOA7 nuclear receptor coactivator 7
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIA nuclear factor I/A
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NISCH nischarin
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NPY2R neuropeptide Y receptor Y2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRADDP neurotrophin receptor associated death domain, pseudogene
NYNRIN NYN domain and retroviral integrase containing
OAT ornithine aminotransferase
ODF3L1 outer dense fiber of sperm tails 3-like 1
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OVOL1 ovo-like zinc finger 1
OXSR1 oxidative stress responsive 1
PALMD palmdelphin
PARP4 poly (ADP-ribose) polymerase family, member 4
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDE12 phosphodiesterase 12
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEG3 paternally expressed 3
PER1 period circadian clock 1
PER2 period circadian clock 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PKP2 plakophilin 2
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLCH2 phospholipase C, eta 2
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLK3 polo-like kinase 3
PLS1 plastin 1
PLXNA2 plexin A2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMEL premelanosome protein
POTEE POTE ankyrin domain family, member E
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRAMEF2 PRAME family member 2
PRICKLE2 prickle homolog 2 (Drosophila)
PRKCD protein kinase C, delta
PRSS22 protease, serine, 22
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGDS ral guanine nucleotide dissociation stimulator
RAP2B RAP2B, member of RAS oncogene family
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RBM47 RNA binding motif protein 47
RBMXL1 RNA binding motif protein, X-linked-like 1
RC3H1 ring finger and CCCH-type domains 1
RDH10 retinol dehydrogenase 10 (all-trans)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RERG RAS-like, estrogen-regulated, growth inhibitor
RND3 Rho family GTPase 3
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
ROR1 receptor tyrosine kinase-like orphan receptor 1
RP1L1 retinitis pigmentosa 1-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SCAP SREBF chaperone
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCPEP1 serine carboxypeptidase 1
SEC1P secretory blood group 1, pseudogene
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERTAD1 SERTA domain containing 1
SGMS2 sphingomyelin synthase 2
SGSM2 small G protein signaling modulator 2
SHF Src homology 2 domain containing F
SIGLEC17P sialic acid binding Ig-like lectin 17, pseudogene
SIGLEC6 sialic acid binding Ig-like lectin 6
SIK1 salt-inducible kinase 1
SLC10A5 solute carrier family 10, member 5
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A9 solute carrier family 16, member 9
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC18B1 solute carrier family 18, subfamily B, member 1
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMC5 structural maintenance of chromosomes 5
SMN1 survival of motor neuron 1, telomeric
SNORA84 small nucleolar RNA, H/ACA box 84
SNORD115-26 small nucleolar RNA, C/D box 115-26
SNX31 sorting nexin 31
SOCS6 suppressor of cytokine signaling 6
SOWAHB sosondowah ankyrin repeat domain family member B
SOX9 SRY (sex determining region Y)-box 9
SPG11 spastic paraplegia 11 (autosomal recessive)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRSF5 serine/arginine-rich splicing factor 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STK17B serine/threonine kinase 17b
STXBP3 syntaxin binding protein 3
SVOPL SVOP-like
SYNGR1 synaptogyrin 1
SYTL4 synaptotagmin-like 4
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D5 TBC1 domain family, member 5
TBCK TBC1 domain containing kinase
TC2N tandem C2 domains, nuclear
TF transferrin
TFCP2L1 transcription factor CP2-like 1
THSD4 thrombospondin, type I, domain containing 4
TICAM1 toll-like receptor adaptor molecule 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TJP3 tight junction protein 3
TLE2 transducin-like enhancer of split 2
TLR5 toll-like receptor 5
TLX1 T-cell leukemia homeobox 1
TM4SF1 transmembrane 4 L six family member 1
TMEM144 transmembrane protein 144
TMEM220 transmembrane protein 220
TMEM30B transmembrane protein 30B
TMEM51-AS1 TMEM51 antisense RNA 1
TMEM63A transmembrane protein 63A
TMEM71 transmembrane protein 71
TMF1 TATA element modulatory factor 1
TMPRSS4 transmembrane protease, serine 4
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TOB1 transducer of ERBB2, 1
TPH2 tryptophan hydroxylase 2
TPPP tubulin polymerization promoting protein
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TPSG1 tryptase gamma 1
TRAK1 trafficking protein, kinesin binding 1
TRIB1 tribbles pseudokinase 1
TSHZ2 teashirt zinc finger homeobox 2
TYR tyrosinase
UBC ubiquitin C
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
USP54 ubiquitin specific peptidase 54
VMO1 vitelline membrane outer layer 1 homolog (chicken)
VNN2 vanin 2
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VWA2 von Willebrand factor A domain containing 2
VWA5A von Willebrand factor A domain containing 5A
WDR6 WD repeat domain 6
WEE1 WEE1 G2 checkpoint kinase
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)
ZBTB21 zinc finger and BTB domain containing 21
ZBTB44 zinc finger and BTB domain containing 44
ZBTB7C zinc finger and BTB domain containing 7C
ZC3H12A zinc finger CCCH-type containing 12A
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZIM2 zinc finger, imprinted 2
ZNF561 zinc finger protein 561
ZNF608 zinc finger protein 608
ZNF648 zinc finger protein 648
ZNF750 zinc finger protein 750
ZSWIM6 zinc finger, SWIM-type containing 6
ZXDB zinc finger, X-linked, duplicated B

low expression

Symbol Name
ZNF526 zinc finger protein 526