Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

400 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAMP angio-associated, migratory cell protein
AANAT aralkylamine N-acetyltransferase
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACOXL acyl-CoA oxidase-like
ACR acrosin
ACVR1 activin A receptor, type I
ADAM20 ADAM metallopeptidase domain 20
ADAP1 ArfGAP with dual PH domains 1
ADCY8 adenylate cyclase 8 (brain)
ADM2 adrenomedullin 2
AGO2 argonaute RISC catalytic component 2
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMIGO1 adhesion molecule with Ig-like domain 1
ANKRD13B ankyrin repeat domain 13B
ANKRD17 ankyrin repeat domain 17
ANKRD40 ankyrin repeat domain 40
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AOC2 amine oxidase, copper containing 2 (retina-specific)
AOX2P aldehyde oxidase 2 pseudogene
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARHGAP8 Rho GTPase activating protein 8
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ART5 ADP-ribosyltransferase 5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BRD3 bromodomain containing 3
BRD7 bromodomain containing 7
BTBD7 BTB (POZ) domain containing 7
C11ORF71 chromosome 11 open reading frame 71
C11ORF95 chromosome 11 open reading frame 95
C16ORF90 chromosome 16 open reading frame 90
C17ORF97 chromosome 17 open reading frame 97
C1QL3 complement component 1, q subcomponent-like 3
C22ORF34 chromosome 22 open reading frame 34
C2ORF71 chromosome 2 open reading frame 71
C2ORF72 chromosome 2 open reading frame 72
C4ORF17 chromosome 4 open reading frame 17
C6ORF15 chromosome 6 open reading frame 15
CABP1 calcium binding protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALCB calcitonin-related polypeptide beta
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAPN8 calpain 8
CASP12 caspase 12 (gene/pseudogene)
CBX6 chromobox homolog 6
CCDC142 coiled-coil domain containing 142
CCDC178 coiled-coil domain containing 178
CCL16 chemokine (C-C motif) ligand 16
CCNA1 cyclin A1
CD180 CD180 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CELA2B chymotrypsin-like elastase family, member 2B
CEMIP cell migration inducing protein, hyaluronan binding
CENPC centromere protein C
CEP164 centrosomal protein 164kDa
CLEC2L C-type lectin domain family 2, member L
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COCH cochlin
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPLX1 complexin 1
CPNE5 copine V
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CRMP1 collapsin response mediator protein 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTPS2 CTP synthase 2
CYB561D1 cytochrome b561 family, member D1
DAPK1 death-associated protein kinase 1
DCPS decapping enzyme, scavenger
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGCR10 DiGeorge syndrome critical region gene 10 (non-protein coding)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DGKG diacylglycerol kinase, gamma 90kDa
DHRSX dehydrogenase/reductase (SDR family) X-linked
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DKFZP434J0226 uncharacterized LOC93429
DPF1 D4, zinc and double PHD fingers family 1
DPH1 diphthamide biosynthesis 1
DSCC1 DNA replication and sister chromatid cohesion 1
DSCR4 Down syndrome critical region 4
DSCR8 Down syndrome critical region 8
DST dystonin
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNLT3 dynein, light chain, Tctex-type 3
EDAR ectodysplasin A receptor
EFCC1 EF-hand and coiled-coil domain containing 1
ELMO1 engulfment and cell motility 1
EML5 echinoderm microtubule associated protein like 5
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHX4 epoxide hydrolase 4
ERC2 ELKS/RAB6-interacting/CAST family member 2
ESRG embryonic stem cell related (non-protein coding)
ETV4 ets variant 4
ETV5 ets variant 5
EYS eyes shut homolog (Drosophila)
FAM120B family with sequence similarity 120B
FAM124B family with sequence similarity 124B
FAM155B family with sequence similarity 155, member B
FAM71F2 family with sequence similarity 71, member F2
FAM83B family with sequence similarity 83, member B
FBN2 fibrillin 2
FBRSL1 fibrosin-like 1
FBXO31 F-box protein 31
FBXO47 F-box protein 47
FCHO1 FCH domain only 1
FCRL5 Fc receptor-like 5
FER1L6 fer-1-like family member 6
FEV FEV (ETS oncogene family)
FGF2 fibroblast growth factor 2 (basic)
FGFR1OP FGFR1 oncogene partner
FGFR2 fibroblast growth factor receptor 2
FKBP6 FK506 binding protein 6, 36kDa
FLJ25758 MAP/microtubule affinity-regulating kinase 1 pseudogene
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXI2 forkhead box I2
FOXL2NB FOXL2 neighbor
FRAS1 Fraser extracellular matrix complex subunit 1
FXR2 fragile X mental retardation, autosomal homolog 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GAGE2E G antigen 2E
GAST gastrin
GFRA3 GDNF family receptor alpha 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA5 gap junction protein, alpha 5, 40kDa
GKN1 gastrokine 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GOLGA5 golgin A5
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR4 G protein-coupled receptor 4
GPR89B G protein-coupled receptor 89B
GSN gelsolin
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM5 glutathione S-transferase mu 5
GTSF1 gametocyte specific factor 1
HDAC4 histone deacetylase 4
HHLA1 HERV-H LTR-associating 1
HIST1H1A histone cluster 1, H1a
HIST1H2BA histone cluster 1, H2ba
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HOXB2 homeobox B2
HOXC8 homeobox C8
HOXD1 homeobox D1
HYOU1 hypoxia up-regulated 1
ICK intestinal cell (MAK-like) kinase
IGFL4 IGF-like family member 4
IL5RA interleukin 5 receptor, alpha
INHBB inhibin, beta B
INHBE inhibin, beta E
INPP5J inositol polyphosphate-5-phosphatase J
IRF4 interferon regulatory factor 4
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITPKB inositol-trisphosphate 3-kinase B
JAKMIP2 janus kinase and microtubule interacting protein 2
JRKL JRK-like
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM2B lysine (K)-specific demethylase 2B
KDM5C lysine (K)-specific demethylase 5C
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1257 KIAA1257
KIAA1804 mixed lineage kinase 4
KIF1A kinesin family member 1A
KIF21A kinesin family member 21A
KSR2 kinase suppressor of ras 2
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LIM2 lens intrinsic membrane protein 2, 19kDa
LIN52 lin-52 DREAM MuvB core complex component
LOC100133985 uncharacterized LOC100133985
LOC100272217 uncharacterized LOC100272217
LOC200726 hCG1657980
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LOC285074 anaphase promoting complex subunit 1 pseudogene
LOC646762 uncharacterized LOC646762
LOC728323 uncharacterized LOC728323
LPPR5 lipid phosphate phosphatase-related protein type 5
LRP12 low density lipoprotein receptor-related protein 12
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC8A leucine rich repeat containing 8 family, member A
LRRN2 leucine rich repeat neuronal 2
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
LY6G6F lymphocyte antigen 6 complex, locus G6F
MAGEA1 melanoma antigen family A1
MAML2 mastermind-like 2 (Drosophila)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC4R melanocortin 4 receptor
MED9 mediator complex subunit 9
MFSD6L major facilitator superfamily domain containing 6-like
MGC16025 uncharacterized LOC85009
MOAP1 modulator of apoptosis 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSI1 musashi RNA-binding protein 1
NAT8L N-acetyltransferase 8-like (GCN5-related, putative)
NBEAP1 neurobeachin pseudogene 1
NBPF1 neuroblastoma breakpoint family, member 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NELFA negative elongation factor complex member A
NEO1 neogenin 1
NEUROG3 neurogenin 3
NHSL1 NHS-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLN neurolysin (metallopeptidase M3 family)
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NRP2 neuropilin 2
NRXN2 neurexin 2
NRXN3 neurexin 3
OPTC opticin
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR52E6 olfactory receptor, family 52, subfamily E, member 6
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR5M10 olfactory receptor, family 5, subfamily M, member 10
OR5M11 olfactory receptor, family 5, subfamily M, member 11
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUD7A OTU deubiquitinase 7A
PAPOLA poly(A) polymerase alpha
PAQR3 progestin and adipoQ receptor family member III
PCDHA10 protocadherin alpha 10
PCDHA13 protocadherin alpha 13
PCDHA5 protocadherin alpha 5
PCDHGA7 protocadherin gamma subfamily A, 7
PCNX pecanex homolog (Drosophila)
PDCD2 programmed cell death 2
PDE9A phosphodiesterase 9A
PELI3 pellino E3 ubiquitin protein ligase family member 3
PGAM5 phosphoglycerate mutase family member 5
PGAP1 post-GPI attachment to proteins 1
PHF2 PHD finger protein 2
PHF3 PHD finger protein 3
PHF8 PHD finger protein 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2G16 phospholipase A2, group XVI
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POPDC3 popeye domain containing 3
PRDM14 PR domain containing 14
PRDM7 PR domain containing 7
PRKX protein kinase, X-linked
PRR18 proline rich 18
PRR5 proline rich 5 (renal)
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PRRC2B proline-rich coiled-coil 2B
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PYGB phosphorylase, glycogen; brain
PYGO1 pygopus family PHD finger 1
QRFP pyroglutamylated RFamide peptide
QRFPR pyroglutamylated RFamide peptide receptor
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAB15 RAB15, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAD21L1 RAD21-like 1 (S. pombe)
RAD51D RAD51 paralog D
RAI1 retinoic acid induced 1
RAP1GAP2 RAP1 GTPase activating protein 2
RGPD8 RANBP2-like and GRIP domain containing 8
RGS6 regulator of G-protein signaling 6
RHOJ ras homolog family member J
RITA1 RBPJ interacting and tubulin associated 1
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KL1 ribosomal protein S6 kinase-like 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SC5D sterol-C5-desaturase
SCARNA1 small Cajal body-specific RNA 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDPR serum deprivation response
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SEPT11 septin 11
SERINC5 serine incorporator 5
SERTAD4 SERTA domain containing 4
SERTM1 serine-rich and transmembrane domain containing 1
SETD1B SET domain containing 1B
SF1 splicing factor 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHH sonic hedgehog
SIGLEC17P sialic acid binding Ig-like lectin 17, pseudogene
SLC16A13 solute carrier family 16, member 13
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMIM10L2A small integral membrane protein 10 like 2A
SMS spermine synthase
SNAR-G1 small ILF3/NF90-associated RNA G1
SNORA32 small nucleolar RNA, H/ACA box 32
SNORA59B small nucleolar RNA, H/ACA box 59B
SORCS3 sortilin-related VPS10 domain containing receptor 3
SOX2 SRY (sex determining region Y)-box 2
SPANXA2 SPANX family, member A2
SPANXB1 SPANX family, member B1
SPANXD SPANX family, member D
SPAST spastin
SPATA31E1 SPATA31 subfamily E, member 1
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPRN shadow of prion protein homolog (zebrafish)
SRSF12 serine/arginine-rich splicing factor 12
ST7-AS2 ST7 antisense RNA 2
ST7L suppression of tumorigenicity 7 like
STAP1 signal transducing adaptor family member 1
STK32B serine/threonine kinase 32B
SYN2 synapsin II
SYNDIG1L synapse differentiation inducing 1-like
SYNJ2BP synaptojanin 2 binding protein
SYT14 synaptotagmin XIV
SYT5 synaptotagmin V
SYTL5 synaptotagmin-like 5
TBP TATA box binding protein
TBX2 T-box 2
TBX20 T-box 20
TCF15 transcription factor 15 (basic helix-loop-helix)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCTA T-cell leukemia translocation altered
TEK TEK tyrosine kinase, endothelial
TEX19 testis expressed 19
TFRC transferrin receptor
TLX2 T-cell leukemia homeobox 2
TMED8 transmembrane emp24 protein transport domain containing 8
TMEM108 transmembrane protein 108
TMEM135 transmembrane protein 135
TMEM14A transmembrane protein 14A
TMEM163 transmembrane protein 163
TMEM178A transmembrane protein 178A
TMEM255B transmembrane protein 255B
TMEM64 transmembrane protein 64
TMEM97 transmembrane protein 97
TMPRSS4 transmembrane protease, serine 4
TOP1MT topoisomerase (DNA) I, mitochondrial
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRAM2 translocation associated membrane protein 2
TRIM74 tripartite motif containing 74
TRIM9 tripartite motif containing 9
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPYL5 TSPY-like 5
TTC7B tetratricopeptide repeat domain 7B
TTC8 tetratricopeptide repeat domain 8
TTLL2 tubulin tyrosine ligase-like family member 2
TTLL7 tubulin tyrosine ligase-like family member 7
TUBB2B tubulin, beta 2B class IIb
TUBE1 tubulin, epsilon 1
TXLNG taxilin gamma
TXNDC11 thioredoxin domain containing 11
TXNRD1 thioredoxin reductase 1
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
UNC119B unc-119 homolog B (C. elegans)
UNC5CL unc-5 homolog C (C. elegans)-like
UPK2 uroplakin 2
USP17L6P ubiquitin specific peptidase 17-like family member 6, pseudogene
USP28 ubiquitin specific peptidase 28
USP44 ubiquitin specific peptidase 44
VAX1 ventral anterior homeobox 1
VPREB1 pre-B lymphocyte 1
WBSCR27 Williams Beuren syndrome chromosome region 27
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1
WNT2B wingless-type MMTV integration site family, member 2B
WNT9A wingless-type MMTV integration site family, member 9A
WT1 Wilms tumor 1
WT1-AS WT1 antisense RNA
YLPM1 YLP motif containing 1
YY2 YY2 transcription factor
ZC2HC1C zinc finger, C2HC-type containing 1C
ZCCHC12 zinc finger, CCHC domain containing 12
ZFAT zinc finger and AT hook domain containing
ZFX zinc finger protein, X-linked
ZFYVE1 zinc finger, FYVE domain containing 1
ZNF217 zinc finger protein 217
ZNF280B zinc finger protein 280B
ZNF490 zinc finger protein 490
ZNF512B zinc finger protein 512B
ZNF664 zinc finger protein 664
ZNF696 zinc finger protein 696
ZNF740 zinc finger protein 740

low expression

Symbol Name
GUF1 GUF1 GTPase homolog (S. cerevisiae)