Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

438 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAA1 aortic aneurysm, familial abdominal 1
AARS alanyl-tRNA synthetase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACACA acetyl-CoA carboxylase alpha
ACLY ATP citrate lyase
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAP1 ArfGAP with dual PH domains 1
ADAT1 adenosine deaminase, tRNA-specific 1
ADCK2 aarF domain containing kinase 2
ADCY7 adenylate cyclase 7
ADD2 adducin 2 (beta)
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL3 adhesion G protein-coupled receptor L3
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AFP alpha-fetoprotein
AGA aspartylglucosaminidase
AHNAK2 AHNAK nucleoprotein 2
AHR aryl hydrocarbon receptor
AKAP3 A kinase (PRKA) anchor protein 3
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANTXR1 anthrax toxin receptor 1
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARSD arylsulfatase D
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATMIN ATM interactor
ATOH7 atonal homolog 7 (Drosophila)
ATP9A ATPase, class II, type 9A
ATRN attractin
ATXN1L ataxin 1-like
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BAG5 BCL2-associated athanogene 5
BBS2 Bardet-Biedl syndrome 2
BFSP1 beaded filament structural protein 1, filensin
BICC1 BicC family RNA binding protein 1
BMP6 bone morphogenetic protein 6
BRD7 bromodomain containing 7
BTC betacellulin
C14ORF132 chromosome 14 open reading frame 132
C16ORF46 chromosome 16 open reading frame 46
C16ORF70 chromosome 16 open reading frame 70
C1ORF198 chromosome 1 open reading frame 198
C1ORF226 chromosome 1 open reading frame 226
C2ORF72 chromosome 2 open reading frame 72
C4ORF17 chromosome 4 open reading frame 17
C7ORF13 chromosome 7 open reading frame 13
C7ORF49 chromosome 7 open reading frame 49
C9ORF106 chromosome 9 open reading frame 106
C9ORF129 chromosome 9 open reading frame 129
C9ORF163 chromosome 9 open reading frame 163
C9ORF43 chromosome 9 open reading frame 43
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALB2 calbindin 2
CAPNS2 calpain, small subunit 2
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBFB core-binding factor, beta subunit
CCDC68 coiled-coil domain containing 68
CCKAR cholecystokinin A receptor
CCSER1 coiled-coil serine-rich protein 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDYL2 chromodomain protein, Y-like 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CENPBD1 CENPB DNA-binding domains containing 1
CERS2 ceramide synthase 2
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CFAP20 cilia and flagella associated protein 20
CHD9 chromodomain helicase DNA binding protein 9
CHMP1A charged multivesicular body protein 1A
CHMP3 charged multivesicular body protein 3
CHRM3 cholinergic receptor, muscarinic 3
CIART circadian associated repressor of transcription
CILP2 cartilage intermediate layer protein 2
CIZ1 CDKN1A interacting zinc finger protein 1
CMIP c-Maf inducing protein
CMTM1 CKLF-like MARVEL transmembrane domain containing 1
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNOT1 CCR4-NOT transcription complex, subunit 1
CNTN3 contactin 3 (plasmacytoma associated)
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COPS7A COP9 signalosome subunit 7A
CPNE2 copine II
CREG2 cellular repressor of E1A-stimulated genes 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CST8 cystatin 8 (cystatin-related epididymal specific)
CTHRC1 collagen triple helix repeat containing 1
CUL1 cullin 1
CUX1 cut-like homeobox 1
CXORF57 chromosome X open reading frame 57
CYS1 cystin 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAKD dephospho-CoA kinase domain containing
DCHS1 dachsous cadherin-related 1
DDR2 discoidin domain receptor tyrosine kinase 2
DEFB132 defensin, beta 132
DERA deoxyribose-phosphate aldolase (putative)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNM1L dynamin 1-like
DOLK dolichol kinase
DSG4 desmoglein 4
DSTN destrin (actin depolymerizing factor)
DTD1 D-tyrosyl-tRNA deacylase 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL2 dynein, light chain, LC8-type 2
DYNLT3 dynein, light chain, Tctex-type 3
EBF4 early B-cell factor 4
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELMO3 engulfment and cell motility 3
EMC8 ER membrane protein complex subunit 8
EML5 echinoderm microtubule associated protein like 5
EPHB6 EPH receptor B6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPRS glutamyl-prolyl-tRNA synthetase
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
FAM114A1 family with sequence similarity 114, member A1
FAM120AOS family with sequence similarity 120A opposite strand
FAM192A family with sequence similarity 192, member A
FAM20B family with sequence similarity 20, member B
FAM210B family with sequence similarity 210, member B
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM66C family with sequence similarity 66, member C
FAM66E family with sequence similarity 66, member E
FBLN2 fibulin 2
FECH ferrochelatase
FERMT1 fermitin family member 1
FGF14 fibroblast growth factor 14
FGF18 fibroblast growth factor 18
FITM2 fat storage-inducing transmembrane protein 2
FMOD fibromodulin
FOXJ2 forkhead box J2
FOXL1 forkhead box L1
FUK fucokinase
G6PD glucose-6-phosphate dehydrogenase
GAL3ST4 galactose-3-O-sulfotransferase 4
GAN gigaxonin
GAS8 growth arrest-specific 8
GCC1 GRIP and coiled-coil domain containing 1
GCLM glutamate-cysteine ligase, modifier subunit
GCSH glycine cleavage system protein H (aminomethyl carrier)
GDA guanine deaminase
GLG1 golgi glycoprotein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNPAT glyceronephosphate O-acyltransferase
GNPDA2 glucosamine-6-phosphate deaminase 2
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPM6B glycoprotein M6B
GPR6 G protein-coupled receptor 6
GPR61 G protein-coupled receptor 61
GPRC5D G protein-coupled receptor, class C, group 5, member D
GREB1 growth regulation by estrogen in breast cancer 1
GRP gastrin-releasing peptide
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GTSE1-AS1 GTSE1 antisense RNA 1 (head to head)
GULP1 GULP, engulfment adaptor PTB domain containing 1
H2BFM H2B histone family, member M
HAPLN1 hyaluronan and proteoglycan link protein 1
HCG9 HLA complex group 9 (non-protein coding)
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HHAT hedgehog acyltransferase
HIGD2B HIG1 hypoxia inducible domain family, member 2B
HIP1 huntingtin interacting protein 1
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H2BE histone cluster 2, H2be
HOXB1 homeobox B1
HRG histidine-rich glycoprotein
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSPA12A heat shock 70kDa protein 12A
HSPA4L heat shock 70kDa protein 4-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
HTRA3 HtrA serine peptidase 3
HYPM huntingtin interacting protein M
IARS isoleucyl-tRNA synthetase
IDNK idnK, gluconokinase homolog (E. coli)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFL3 IGF-like family member 3
INA internexin neuronal intermediate filament protein, alpha
INS-IGF2 INS-IGF2 readthrough
INSIG1 insulin induced gene 1
IPO8 importin 8
ISLR immunoglobulin superfamily containing leucine-rich repeat
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA11 integrin, alpha 11
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCTD16 potassium channel tetramerization domain containing 16
KDM5A lysine (K)-specific demethylase 5A
KGFLP2 keratinocyte growth factor-like protein 2
KIAA0319 KIAA0319
KIAA1210 KIAA1210
KIAA1549L KIAA1549-like
KIF16B kinesin family member 16B
KIF26A kinesin family member 26A
KIF26B kinesin family member 26B
KLHL10 kelch-like family member 10
KLHL12 kelch-like family member 12
KLHL20 kelch-like family member 20
KLHL36 kelch-like family member 36
KLHL42 kelch-like family member 42
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP5 lysosomal-associated membrane protein family, member 5
LBH limb bud and heart development
LDOC1 leucine zipper, down-regulated in cancer 1
LIMK1 LIM domain kinase 1
LINC00113 long intergenic non-protein coding RNA 113
LINC00167 long intergenic non-protein coding RNA 167
LINC00235 long intergenic non-protein coding RNA 235
LINC01559 long intergenic non-protein coding RNA 1559
LOC100272217 uncharacterized LOC100272217
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LOH12CR2 loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
LONP2 lon peptidase 2, peroxisomal
LPA lipoprotein, Lp(a)
LPCAT2 lysophosphatidylcholine acyltransferase 2
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC29 leucine rich repeat containing 29
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC8A leucine rich repeat containing 8 family, member A
LTBP4 latent transforming growth factor beta binding protein 4
LUZP6 leucine zipper protein 6
MAGEE2 melanoma antigen family E2
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP2 microtubule-associated protein 2
MARVELD3 MARVEL domain containing 3
MBTPS1 membrane-bound transcription factor peptidase, site 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MKX mohawk homeobox
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
MTSS1L metastasis suppressor 1-like
MXRA5 matrix-remodelling associated 5
MYH10 myosin, heavy chain 10, non-muscle
MYH14 myosin, heavy chain 14, non-muscle
MYO1D myosin ID
NAE1 NEDD8 activating enzyme E1 subunit 1
NAV1 neuron navigator 1
NCS1 neuronal calcium sensor 1
NDNF neuron-derived neurotrophic factor
NDRG4 NDRG family member 4
NECAB2 N-terminal EF-hand calcium binding protein 2
NEGR1 neuronal growth regulator 1
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKX1-2 NK1 homeobox 2
NKX3-2 NK3 homeobox 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRSN2 neurensin 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP205 nucleoporin 205kDa
NUP214 nucleoporin 214kDa
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OMD osteomodulin
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OR5M11 olfactory receptor, family 5, subfamily M, member 11
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OR9A4 olfactory receptor, family 9, subfamily A, member 4
OSGIN1 oxidative stress induced growth inhibitor 1
OTUD7A OTU deubiquitinase 7A
PALLD palladin, cytoskeletal associated protein
PANX2 pannexin 2
PAPPA2 pappalysin 2
PARVA parvin, alpha
PCDHB10 protocadherin beta 10
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGBD5 piggyBac transposable element derived 5
PHKB phosphorylase kinase, beta
PITRM1 pitrilysin metallopeptidase 1
PLBD2 phospholipase B domain containing 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PNPLA4 patatin-like phospholipase domain containing 4
PRDM12 PR domain containing 12
PRELP proline/arginine-rich end leucine-rich repeat protein
PRR5L proline rich 5 like
PRRC2B proline-rich coiled-coil 2B
PRSS35 protease, serine, 35
PSAT1 phosphoserine aminotransferase 1
PSKH1 protein serine kinase H1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTHLH parathyroid hormone-like hormone
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYGB phosphorylase, glycogen; brain
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
RAB3B RAB3B, member RAS oncogene family
RHBDD1 rhomboid domain containing 1
RHBDD2 rhomboid domain containing 2
RIT1 Ras-like without CAAX 1
RPGRIP1L RPGRIP1-like
RPL23AP53 ribosomal protein L23a pseudogene 53
RSPO2 R-spondin 2
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP4 relaxin/insulin-like family peptide receptor 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23B Sec23 homolog B (S. cerevisiae)
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT11 septin 11
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGCZ sarcoglycan, zeta
SGK223 homolog of rat pragma of Rnd2
SGPL1 sphingosine-1-phosphate lyase 1
SHISA6 shisa family member 6
SKIL SKI-like proto-oncogene
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A13 solute carrier family 16, member 13
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC38A7 solute carrier family 38, member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC44A2 solute carrier family 44 (choline transporter), member 2
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SLX4IP SLX4 interacting protein
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOGA1 suppressor of glucose, autophagy associated 1
SPANXA2 SPANX family, member A2
SPANXD SPANX family, member D
SPATA45 spermatogenesis associated 45
SPDYE3 speedy/RINGO cell cycle regulator family member E3
SRXN1 sulfiredoxin 1
SSC5D scavenger receptor cysteine rich family, 5 domains
SSTR4 somatostatin receptor 4
ST7-AS2 ST7 antisense RNA 2
STK32B serine/threonine kinase 32B
STRAP serine/threonine kinase receptor associated protein
SULF1 sulfatase 1
SYNDIG1 synapse differentiation inducing 1
SYNPR synaptoporin
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D20 TBC1 domain family, member 20
TBCK TBC1 domain containing kinase
TBL1X transducin (beta)-like 1X-linked
TCAF1 TRPM8 channel-associated factor 1
TCF4 transcription factor 4
TCTEX1D2 Tctex1 domain containing 2
TECTA tectorin alpha
TERF2 telomeric repeat binding factor 2
TGM6 transglutaminase 6
THBD thrombomodulin
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMP2 TIMP metallopeptidase inhibitor 2
TLN2 talin 2
TLX1 T-cell leukemia homeobox 1
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM106B transmembrane protein 106B
TNPO3 transportin 3
TP53INP2 tumor protein p53 inducible nuclear protein 2
TSGA13 testis specific, 13
TSPAN18 tetraspanin 18
TSPAN9 tetraspanin 9
TTLL2 tubulin tyrosine ligase-like family member 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE3C ubiquitin protein ligase E3C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5
ULBP1 UL16 binding protein 1
UNC5B unc-5 homolog B (C. elegans)
UPK1B uroplakin 1B
USP10 ubiquitin specific peptidase 10
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTRN utrophin
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCAN versican
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
WASF1 WAS protein family, member 1
WBSCR27 Williams Beuren syndrome chromosome region 27
WDR31 WD repeat domain 31
WFS1 Wolfram syndrome 1 (wolframin)
WNT2 wingless-type MMTV integration site family member 2
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZC3H18 zinc finger CCCH-type containing 18
ZDHHC1 zinc finger, DHHC-type containing 1
ZDHHC9 zinc finger, DHHC-type containing 9
ZFP90 ZFP90 zinc finger protein
ZFPM1 zinc finger protein, FOG family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF319 zinc finger protein 319

low expression

Symbol Name
C17ORF80 chromosome 17 open reading frame 80
FAM104A family with sequence similarity 104, member A
HEXIM1 hexamethylene bis-acetamide inducible 1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
MESDC2 mesoderm development candidate 2
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
RNF31 ring finger protein 31
TLK2 tousled-like kinase 2