Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7090-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

348 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7090-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACE angiotensin I converting enzyme
ACTB actin, beta
ACTN1 actinin, alpha 1
ADAM10 ADAM metallopeptidase domain 10
ADAM9 ADAM metallopeptidase domain 9
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAR adenosine deaminase, RNA-specific
AHCYL2 adenosylhomocysteinase-like 2
AHNAK2 AHNAK nucleoprotein 2
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC4 anaphase promoting complex subunit 4
ANGPT2 angiopoietin 2
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANPEP alanyl (membrane) aminopeptidase
ANTXR2 anthrax toxin receptor 2
APCDD1 adenomatosis polyposis coli down-regulated 1
APOL6 apolipoprotein L, 6
ARHGAP5 Rho GTPase activating protein 5
ARL4C ADP-ribosylation factor-like 4C
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP10D ATPase, class V, type 10D
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
AVPR1A arginine vasopressin receptor 1A
B2M beta-2-microglobulin
B3GALTL beta 1,3-galactosyltransferase-like
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BDKRB2 bradykinin receptor B2
C11ORF45 chromosome 11 open reading frame 45
C14ORF169 chromosome 14 open reading frame 169
C17ORF51 chromosome 17 open reading frame 51
C1QC complement component 1, q subcomponent, C chain
CA12 carbonic anhydrase XII
CAB39 calcium binding protein 39
CALN1 calneuron 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CARD10 caspase recruitment domain family, member 10
CASP14 caspase 14, apoptosis-related cysteine peptidase
CCDC149 coiled-coil domain containing 149
CCDC3 coiled-coil domain containing 3
CCDC70 coiled-coil domain containing 70
CCL13 chemokine (C-C motif) ligand 13
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCNG2 cyclin G2
CCR1 chemokine (C-C motif) receptor 1
CD276 CD276 molecule
CD68 CD68 molecule
CDH13 cadherin 13
CDYL2 chromodomain protein, Y-like 2
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CFHR1 complement factor H-related 1
CHSY1 chondroitin sulfate synthase 1
CKAP2 cytoskeleton associated protein 2
CLDN14 claudin 14
CLSTN1 calsyntenin 1
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
COL12A1 collagen, type XII, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CRYBB1 crystallin, beta B1
CSMD2 CUB and Sushi multiple domains 2
CSPG4 chondroitin sulfate proteoglycan 4
CXCR1 chemokine (C-X-C motif) receptor 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF4 DDB1 and CUL4 associated factor 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEPDC7 DEP domain containing 7
DHRS7 dehydrogenase/reductase (SDR family) member 7
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DST dystonin
DTX3L deltex 3 like, E3 ubiquitin ligase
EDNRA endothelin receptor type A
EFNB1 ephrin-B1
EFTUD1 elongation factor Tu GTP binding domain containing 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EML1 echinoderm microtubule associated protein like 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESM1 endothelial cell-specific molecule 1
EVC Ellis van Creveld protein
EXT1 exostosin glycosyltransferase 1
FAM155B family with sequence similarity 155, member B
FAM205A family with sequence similarity 205, member A
FAM205BP transmembrane protein C9orf144B pseudogene
FAM63B family with sequence similarity 63, member B
FAM83H family with sequence similarity 83, member H
FAT1 FAT atypical cadherin 1
FERMT1 fermitin family member 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FOLR2 folate receptor 2 (fetal)
FSCN1 fascin actin-bundling protein 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GAL3ST4 galactose-3-O-sulfotransferase 4
GANC glucosidase, alpha; neutral C
GDNF glial cell derived neurotrophic factor
GLI3 GLI family zinc finger 3
GLIPR2 GLI pathogenesis-related 2
GLRA4 glycine receptor, alpha 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPR68 G protein-coupled receptor 68
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSDMC gasdermin C
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BE histone cluster 1, H2be
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BO histone cluster 1, H2bo
HIST1H3A histone cluster 1, H3a
HLA-H major histocompatibility complex, class I, H (pseudogene)
HPCAL1 hippocalcin-like 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA17 interferon, alpha 17
IFNK interferon, kappa
IL20 interleukin 20
IL3 interleukin 3
IL6R interleukin 6 receptor
IQCA1 IQ motif containing with AAA domain 1
IRF2BPL interferon regulatory factor 2 binding protein-like
IRF9 interferon regulatory factor 9
IRS1 insulin receptor substrate 1
ISM1 isthmin 1, angiogenesis inhibitor
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
JAG2 jagged 2
JDP2 Jun dimerization protein 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0196 KIAA0196
KIAA1429 KIAA1429
KIAA1644 KIAA1644
KIF13A kinesin family member 13A
KIRREL kin of IRRE like (Drosophila)
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMA3 laminin, alpha 3
LAMA5 laminin, alpha 5
LARGE like-glycosyltransferase
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX1 LIM homeobox 1
LIMK2 LIM domain kinase 2
LMF2 lipase maturation factor 2
LOC100133985 uncharacterized LOC100133985
LOC285629 uncharacterized LOC285629
LOC644936 actin, beta pseudogene
LRP12 low density lipoprotein receptor-related protein 12
LTBP1 latent transforming growth factor beta binding protein 1
MAB21L2 mab-21-like 2 (C. elegans)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MESDC1 mesoderm development candidate 1
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGC45800
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKL1 megakaryoblastic leukemia (translocation) 1
MKX mohawk homeobox
MMP12 matrix metallopeptidase 12
MN1 meningioma (disrupted in balanced translocation) 1
MOXD1 monooxygenase, DBH-like 1
MS4A14 membrane-spanning 4-domains, subfamily A, member 14
MSN moesin
MSR1 macrophage scavenger receptor 1
MST1R macrophage stimulating 1 receptor
MTDH metadherin
MYH9 myosin, heavy chain 9, non-muscle
MYO10 myosin X
MYO5A myosin VA (heavy chain 12, myoxin)
MYO7B myosin VIIB
NAV1 neuron navigator 1
NCALD neurocalcin delta
NCS1 neuronal calcium sensor 1
NFIB nuclear factor I/B
NGEF neuronal guanine nucleotide exchange factor
NLGN4X neuroligin 4, X-linked
NLGN4Y neuroligin 4, Y-linked
NPR2 natriuretic peptide receptor 2
NPR3 natriuretic peptide receptor 3
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NT5E 5'-nucleotidase, ecto (CD73)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFM2 olfactomedin 2
OR13F1 olfactory receptor, family 13, subfamily F, member 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OSCAR osteoclast associated, immunoglobulin-like receptor
P3H2 prolyl 3-hydroxylase 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDH7 protocadherin 7
PCDHA2 protocadherin alpha 2
PCDHB4 protocadherin beta 4
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGC5 protocadherin gamma subfamily C, 5
PCNX pecanex homolog (Drosophila)
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE7A phosphodiesterase 7A
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDS5B PDS5 cohesin associated factor B
PHF20L1 PHD finger protein 20-like 1
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PILRA paired immunoglobin-like type 2 receptor alpha
PITPNB phosphatidylinositol transfer protein, beta
PLCD4 phospholipase C, delta 4
PLCG1 phospholipase C, gamma 1
PLEC plectin
PLEK2 pleckstrin 2
PLXNB2 plexin B2
PML promyelocytic leukemia
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POTEM POTE ankyrin domain family, member M
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PQLC3 PQ loop repeat containing 3
PSEN1 presenilin 1
PTK2 protein tyrosine kinase 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRK protein tyrosine phosphatase, receptor type, K
RAB30 RAB30, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGEF1B RasGEF domain family, member 1B
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM28 RNA binding motif protein 28
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RELL1 RELT-like 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF185 ring finger protein 185
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RSAD2 radical S-adenosyl methionine domain containing 2
RXFP3 relaxin/insulin-like family peptide receptor 3
SCG5 secretogranin V
SCN4B sodium channel, voltage gated, type IV beta subunit
SDK2 sidekick cell adhesion molecule 2
SEC23A Sec23 homolog A (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH2D2A SH2 domain containing 2A
SH2D5 SH2 domain containing 5
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC25A30 solute carrier family 25, member 30
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35E4 solute carrier family 35, member E4
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLFN5 schlafen family member 5
SLITRK6 SLIT and NTRK-like family, member 6
SMIM20 small integral membrane protein 20
SMTN smoothelin
SNAI2 snail family zinc finger 2
SND1 staphylococcal nuclease and tudor domain containing 1
SP100 SP100 nuclear antigen
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SPPL2A signal peptide peptidase like 2A
SPRED1 sprouty-related, EVH1 domain containing 1
SRPK2 SRSF protein kinase 2
STON2 stonin 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYT7 synaptotagmin VII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCF20 transcription factor 20 (AR1)
TEF thyrotrophic embryonic factor
TGS1 trimethylguanosine synthase 1
THSD1 thrombospondin, type I, domain containing 1
TIGD5 tigger transposable element derived 5
TLL1 tolloid-like 1
TM9SF1 transmembrane 9 superfamily member 1
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM140 transmembrane protein 140
TMEM150B transmembrane protein 150B
TMEM184B transmembrane protein 184B
TMEM33 transmembrane protein 33
TMEM64 transmembrane protein 64
TMEM74 transmembrane protein 74
TMEM87A transmembrane protein 87A
TOX thymocyte selection-associated high mobility group box
TP53I11 tumor protein p53 inducible protein 11
TP63 tumor protein p63
TRIM69 tripartite motif containing 69
TSPAN5 tetraspanin 5
TSSK1B testis-specific serine kinase 1B
TTC7A tetratricopeptide repeat domain 7A
TTC7B tetratricopeptide repeat domain 7B
TTLL11 tubulin tyrosine ligase-like family member 11
TTTY16 testis-specific transcript, Y-linked 16 (non-protein coding)
TYMP thymidine phosphorylase
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBQLN2 ubiquilin 2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
ULK2 unc-51 like autophagy activating kinase 2
USP18 ubiquitin specific peptidase 18
USP50 ubiquitin specific peptidase 50
USP9Y ubiquitin specific peptidase 9, Y-linked
VAV2 vav 2 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIPR1 vasoactive intestinal peptide receptor 1
WDR91 WD repeat domain 91
WNT10A wingless-type MMTV integration site family, member 10A
WNT9B wingless-type MMTV integration site family, member 9B
YLPM1 YLP motif containing 1
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBED4 zinc finger, BED-type containing 4
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP41 ZFP41 zinc finger protein
ZNF609 zinc finger protein 609
ZNF788 zinc finger family member 788
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZPBP zona pellucida binding protein
ZSCAN31 zinc finger and SCAN domain containing 31
ZYX zyxin

low expression

Symbol Name
COPG2 coatomer protein complex, subunit gamma 2