Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

375 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAM8 ADAM metallopeptidase domain 8
ADAMTSL4 ADAMTS-like 4
ADAP1 ArfGAP with dual PH domains 1
ADIPOR1 adiponectin receptor 1
AHCYL2 adenosylhomocysteinase-like 2
AHNAK2 AHNAK nucleoprotein 2
AJUBA ajuba LIM protein
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ANKRD13B ankyrin repeat domain 13B
ANLN anillin, actin binding protein
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AQP6 aquaporin 6, kidney specific
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRDC1 arrestin domain containing 1
ASB7 ankyrin repeat and SOCS box containing 7
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAGE B melanoma antigen
BAGE2 B melanoma antigen family, member 2
BCAR3 breast cancer anti-estrogen resistance 3
BCL2L1 BCL2-like 1
BIVM basic, immunoglobulin-like variable motif containing
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BORA bora, aurora kinase A activator
BTBD16 BTB (POZ) domain containing 16
C10ORF67 chromosome 10 open reading frame 67
C10ORF91 chromosome 10 open reading frame 91
C16ORF54 chromosome 16 open reading frame 54
C19ORF26 chromosome 19 open reading frame 26
C5ORF51 chromosome 5 open reading frame 51
C6ORF106 chromosome 6 open reading frame 106
CARD10 caspase recruitment domain family, member 10
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CASC5 cancer susceptibility candidate 5
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC3 coiled-coil domain containing 3
CCSAP centriole, cilia and spindle-associated protein
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC25B cell division cycle 25B
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH16 cadherin 16, KSP-cadherin
CDR2L cerebellar degeneration-related protein 2-like
CENPF centromere protein F, 350/400kDa
CEP55 centrosomal protein 55kDa
CEP72 centrosomal protein 72kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CERS4 ceramide synthase 4
CES2 carboxylesterase 2
CKMT1A creatine kinase, mitochondrial 1A
CKMT1B creatine kinase, mitochondrial 1B
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CPA4 carboxypeptidase A4
CPO carboxypeptidase O
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB1 cAMP responsive element binding protein 1
CSAG3 CSAG family, member 3
CTH cystathionine gamma-lyase
CYB5R1 cytochrome b5 reductase 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DBT dihydrolipoamide branched chain transacylase E2
DEPDC1 DEP domain containing 1
DKFZP434K028 uncharacterized LOC26070
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLK2 delta-like 2 homolog (Drosophila)
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DOCK1 dedicator of cytokinesis 1
DOCK5 dedicator of cytokinesis 5
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPP9 dipeptidyl-peptidase 9
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DROSHA drosha, ribonuclease type III
DUXA double homeobox A
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPO erythropoietin
ERCC5 excision repair cross-complementation group 5
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
ESPNL espin-like
FAM102B family with sequence similarity 102, member B
FAM120A family with sequence similarity 120A
FAM213A family with sequence similarity 213, member A
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FAM89A family with sequence similarity 89, member A
FGF11 fibroblast growth factor 11
FGF13 fibroblast growth factor 13
FGFBP1 fibroblast growth factor binding protein 1
GALK2 galactokinase 2
GAST gastrin
GCNT7 glucosaminyl (N-acetyl) transferase family member 7
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGT1 gamma-glutamyltransferase 1
GGT3P gamma-glutamyltransferase 3 pseudogene
GGTLC1 gamma-glutamyltransferase light chain 1
GGTLC2 gamma-glutamyltransferase light chain 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJB4 gap junction protein, beta 4, 30.3kDa
GJC2 gap junction protein, gamma 2, 47kDa
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA3 golgin A3
GPR39 G protein-coupled receptor 39
GPSM2 G-protein signaling modulator 2
H1F0 H1 histone family, member 0
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBBP1 hemoglobin, beta pseudogene 1
HBE1 hemoglobin, epsilon 1
HES5 hes family bHLH transcription factor 5
HES7 hes family bHLH transcription factor 7
HKDC1 hexokinase domain containing 1
HMGA2 high mobility group AT-hook 2
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSPA2 heat shock 70kDa protein 2
HYAL1 hyaluronoglucosaminidase 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICE1 interactor of little elongation complex ELL subunit 1
IFNA13 interferon, alpha 13
IFNA8 interferon, alpha 8
IFNLR1 interferon, lambda receptor 1
IL1RL2 interleukin 1 receptor-like 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPG1 interphotoreceptor matrix proteoglycan 1
INCENP inner centromere protein antigens 135/155kDa
IRF6 interferon regulatory factor 6
ITPK1-AS1 ITPK1 antisense RNA 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK4 potassium channel, two pore domain subfamily K, member 4
KDF1 keratinocyte differentiation factor 1
KDSR 3-ketodihydrosphingosine reductase
KIAA1804 mixed lineage kinase 4
KIF14 kinesin family member 14
KIF16B kinesin family member 16B
KIF17 kinesin family member 17
KIF3C kinesin family member 3C
KLK5 kallikrein-related peptidase 5
KPNA6 karyopherin alpha 6 (importin alpha 7)
LAD1 ladinin 1
LCLAT1 lysocardiolipin acyltransferase 1
LGTN ligatin
LINC00336 long intergenic non-protein coding RNA 336
LINC00593 long intergenic non-protein coding RNA 593
LINC01588 long intergenic non-protein coding RNA 1588
LINC01590 long intergenic non-protein coding RNA 1590
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LOC284632 uncharacterized LOC284632
LOC284788 uncharacterized LOC284788
LPAR3 lysophosphatidic acid receptor 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP11 low density lipoprotein receptor-related protein 11
LRRC8D leucine rich repeat containing 8 family, member D
LRRK1 leucine-rich repeat kinase 1
LRRN4 leucine rich repeat neuronal 4
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYST lysosomal trafficking regulator
MAGEA1 melanoma antigen family A1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MAVS mitochondrial antiviral signaling protein
MCTP2 multiple C2 domains, transmembrane 2
MCU mitochondrial calcium uniporter
MED18 mediator complex subunit 18
METRN meteorin, glial cell differentiation regulator
METTL2B methyltransferase like 2B
MFAP5 microfibrillar associated protein 5
MISP mitotic spindle positioning
MKI67 marker of proliferation Ki-67
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOCS3 molybdenum cofactor synthesis 3
MORN3 MORN repeat containing 3
MSLN mesothelin
MST1R macrophage stimulating 1 receptor
MTSS1L metastasis suppressor 1-like
MYO1C myosin IC
MYO1G myosin IG
NDE1 nudE neurodevelopment protein 1
NEK2 NIMA-related kinase 2
NIPBL Nipped-B homolog (Drosophila)
NPY4R neuropeptide Y receptor Y4
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
NUTM1 NUT midline carcinoma, family member 1
OLFML2A olfactomedin-like 2A
ONECUT3 one cut homeobox 3
OR13H1 olfactory receptor, family 13, subfamily H, member 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR51B5 olfactory receptor, family 51, subfamily B, member 5
OR51B6 olfactory receptor, family 51, subfamily B, member 6
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR51M1 olfactory receptor, family 51, subfamily M, member 1
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR5B12 olfactory receptor, family 5, subfamily B, member 12
OTUD1 OTU deubiquitinase 1
OTULIN OTU deubiquitinase with linear linkage specificity
PAQR7 progestin and adipoQ receptor family member VII
PCSK6 proprotein convertase subtilisin/kexin type 6
PDZD9 PDZ domain containing 9
PDZK1 PDZ domain containing 1
PEAR1 platelet endothelial aggregation receptor 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PNPO pyridoxamine 5'-phosphate oxidase
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
POU4F3 POU class 4 homeobox 3
PP14571 uncharacterized LOC100130449
PPARD peroxisome proliferator-activated receptor delta
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP6R3 protein phosphatase 6, regulatory subunit 3
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PROCR protein C receptor, endothelial
PRODH proline dehydrogenase (oxidase) 1
PRR11 proline rich 11
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTH2R parathyroid hormone 2 receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRA protein tyrosine phosphatase, receptor type, A
PTRF polymerase I and transcript release factor
PTX4 pentraxin 4, long
PWWP2B PWWP domain containing 2B
PXN paxillin
RAB22A RAB22A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM44 RNA binding motif protein 44
RBMS2 RNA binding motif, single stranded interacting protein 2
RDH16 retinol dehydrogenase 16 (all-trans)
REEP1 receptor accessory protein 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RNF6 ring finger protein (C3H2C3 type) 6
RNPEP arginyl aminopeptidase (aminopeptidase B)
RSG1 REM2 and RAB-like small GTPase 1
SAMD4A sterile alpha motif domain containing 4A
SC5D sterol-C5-desaturase
SCARNA17 small Cajal body-specific RNA 17
SCD5 stearoyl-CoA desaturase 5
SCP2D1 SCP2 sterol-binding domain containing 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SFTA1P surfactant associated 1, pseudogene
SFXN3 sideroflexin 3
SGOL2 shugoshin-like 2 (S. pombe)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35F2 solute carrier family 35, member F2
SLC35F3 solute carrier family 35, member F3
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC38A8 solute carrier family 38, member 8
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLMO2 slowmo homolog 2 (Drosophila)
SNORA71A small nucleolar RNA, H/ACA box 71A
SNORD115-26 small nucleolar RNA, C/D box 115-26
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SOX13 SRY (sex determining region Y)-box 13
SPDYC speedy/RINGO cell cycle regulator family member C
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STK24 serine/threonine kinase 24
STK35 serine/threonine kinase 35
STK4 serine/threonine kinase 4
STON1 stonin 1
STPG1 sperm-tail PG-rich repeat containing 1
STRIP2 striatin interacting protein 2
STX3 syntaxin 3
SZRD1 SUZ RNA binding domain containing 1
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TBRG1 transforming growth factor beta regulator 1
TBX18 T-box 18
TBX6 T-box 6
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TEX40 testis expressed 40
TLX1 T-cell leukemia homeobox 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM189 transmembrane protein 189
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM230 transmembrane protein 230
TMEM86A transmembrane protein 86A
TMEM88 transmembrane protein 88
TMOD3 tropomodulin 3 (ubiquitous)
TMPPE transmembrane protein with metallophosphoesterase domain
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1
TOR4A torsin family 4, member A
TPP2 tripeptidyl peptidase II
TPPP tubulin polymerization promoting protein
TPPP3 tubulin polymerization-promoting protein family member 3
TPTE transmembrane phosphatase with tensin homology
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSPAN1 tetraspanin 1
TTC23 tetratricopeptide repeat domain 23
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBAC2 UBA domain containing 2
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UFM1 ubiquitin-fold modifier 1
UGT8 UDP glycosyltransferase 8
UNC13D unc-13 homolog D (C. elegans)
UPK2 uroplakin 2
UPK3B uroplakin 3B
USP28 ubiquitin specific peptidase 28
UTS2 urotensin 2
VANGL1 VANGL planar cell polarity protein 1
VRTN vertebrae development associated
VSIG1 V-set and immunoglobulin domain containing 1
VSIG10 V-set and immunoglobulin domain containing 10
WDR47 WD repeat domain 47
WNT10A wingless-type MMTV integration site family, member 10A
WNT2B wingless-type MMTV integration site family, member 2B
WNT3A wingless-type MMTV integration site family, member 3A
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBTB3 zinc finger and BTB domain containing 3
ZC2HC1B zinc finger, C2HC-type containing 1B
ZC3H11A zinc finger CCCH-type containing 11A
ZG16 zymogen granule protein 16
ZMYM1 zinc finger, MYM-type 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF114 zinc finger protein 114
ZNF192P1 zinc finger protein 192 pseudogene 1
ZNF487 zinc finger protein 487
ZNF488 zinc finger protein 488
ZPLD1 zona pellucida-like domain containing 1
ZSWIM1 zinc finger, SWIM-type containing 1

low expression

Symbol Name
BCDIN3D BCDIN3 domain containing
BCL7B B-cell CLL/lymphoma 7B
EXOC7 exocyst complex component 7
HDAC3 histone deacetylase 3
NUBP1 nucleotide binding protein 1
PAIP2 poly(A) binding protein interacting protein 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHF20L1 PHD finger protein 20-like 1
RMDN1 regulator of microtubule dynamics 1
SCAF4 SR-related CTD-associated factor 4
TIGD6 tigger transposable element derived 6
TOP2B topoisomerase (DNA) II beta 180kDa
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
ZNF16 zinc finger protein 16
ZNF252P zinc finger protein 252, pseudogene
ZNF346 zinc finger protein 346
ZNF76 zinc finger protein 76
ZNF839 zinc finger protein 839