Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5979-01A-11R-1686-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

427 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5979-01A-11R-1686-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAMTSL4 ADAMTS-like 4
ADGRG1 adhesion G protein-coupled receptor G1
ADM adrenomedullin
AGA aspartylglucosaminidase
AGRN agrin
AJUBA ajuba LIM protein
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANGPTL4 angiopoietin-like 4
ANKRD49 ankyrin repeat domain 49
ANLN anillin, actin binding protein
ANO6 anoctamin 6
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APCDD1L adenomatosis polyposis coli down-regulated 1-like
APLN apelin
ARG2 arginase 2
ARHGAP22 Rho GTPase activating protein 22
ARHGAP29 Rho GTPase activating protein 29
ARHGAP42 Rho GTPase activating protein 42
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL4C ADP-ribosylation factor-like 4C
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASIC2 acid sensing (proton gated) ion channel 2
ATMIN ATM interactor
AXL AXL receptor tyrosine kinase
B3GNT1
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BCAR1 breast cancer anti-estrogen resistance 1
BDKRB1 bradykinin receptor B1
BIRC2 baculoviral IAP repeat containing 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRMS1 breast cancer metastasis suppressor 1
C11ORF68 chromosome 11 open reading frame 68
C11ORF70 chromosome 11 open reading frame 70
C11ORF73 chromosome 11 open reading frame 73
C11ORF80 chromosome 11 open reading frame 80
C16ORF46 chromosome 16 open reading frame 46
C16ORF87 chromosome 16 open reading frame 87
C4ORF36 chromosome 4 open reading frame 36
C5ORF28 chromosome 5 open reading frame 28
C5ORF34 chromosome 5 open reading frame 34
C5ORF51 chromosome 5 open reading frame 51
C8ORF48 chromosome 8 open reading frame 48
C8ORF58 chromosome 8 open reading frame 58
C9ORF170 chromosome 9 open reading frame 170
CAPN2 calpain 2, (m/II) large subunit
CARD10 caspase recruitment domain family, member 10
CAV2 caveolin 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC102A coiled-coil domain containing 102A
CCDC113 coiled-coil domain containing 113
CCDC169 coiled-coil domain containing 169
CCDC82 coiled-coil domain containing 82
CCDC85C coiled-coil domain containing 85C
CCDC92 coiled-coil domain containing 92
CCNK cyclin K
CCSAP centriole, cilia and spindle-associated protein
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH13 cadherin 13
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK18 cyclin-dependent kinase 18
CEP126 centrosomal protein 126kDa
CEP170B centrosomal protein 170B
CEP57 centrosomal protein 57kDa
CERCAM cerebral endothelial cell adhesion molecule
CFAP58 cilia and flagella associated protein 58
CFL1 cofilin 1 (non-muscle)
CGB8 chorionic gonadotropin, beta polypeptide 8
CHD1L chromodomain helicase DNA binding protein 1-like
CHKA choline kinase alpha
CHPF chondroitin polymerizing factor
CHPF2 chondroitin polymerizing factor 2
CIART circadian associated repressor of transcription
CNTNAP3 contactin associated protein-like 3
COL13A1 collagen, type XIII, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL17A1 collagen, type XVII, alpha 1
CORO1B coronin, actin binding protein, 1B
COTL1 coactosin-like F-actin binding protein 1
CPA4 carboxypeptidase A4
CREBZF CREB/ATF bZIP transcription factor
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRIP2 cysteine-rich protein 2
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSMD3 CUB and Sushi multiple domains 3
CSNK2A2 casein kinase 2, alpha prime polypeptide
CT62 cancer/testis antigen 62
CTTN cortactin
CWC15 CWC15 spliceosome-associated protein
CXORF58 chromosome X open reading frame 58
CYB5R1 cytochrome b5 reductase 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAOA D-amino acid oxidase activator
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
DENND2A DENN/MADD domain containing 2A
DEPDC7 DEP domain containing 7
DFNA5 deafness, autosomal dominant 5
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIAPH3 diaphanous-related formin 3
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK5 dedicator of cytokinesis 5
DPP3 dipeptidyl-peptidase 3
DPP9 dipeptidyl-peptidase 9
DST dystonin
DUSP4 dual specificity phosphatase 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EED embryonic ectoderm development
EFCAB5 EF-hand calcium binding domain 5
EGLN3 egl-9 family hypoxia-inducible factor 3
EHD2 EH-domain containing 2
EML1 echinoderm microtubule associated protein like 1
EMP3 epithelial membrane protein 3
ENDOD1 endonuclease domain containing 1
ENO2 enolase 2 (gamma, neuronal)
ERCC2 excision repair cross-complementation group 2
EVC Ellis van Creveld protein
EVI5L ecotropic viral integration site 5-like
EXOSC6 exosome component 6
EXT1 exostosin glycosyltransferase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM180A family with sequence similarity 180, member A
FAM181B family with sequence similarity 181, member B
FAM210A family with sequence similarity 210, member A
FAM65A family with sequence similarity 65, member A
FAM69A family with sequence similarity 69, member A
FAM76B family with sequence similarity 76, member B
FAT1 FAT atypical cadherin 1
FBLN7 fibulin 7
FBXO4 F-box protein 4
FCHSD2 FCH and double SH3 domains 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF5 fibroblast growth factor 5
FHOD1 formin homology 2 domain containing 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FKRP fukutin related protein
FLII flightless I homolog (Drosophila)
FOLR3 folate receptor 3 (gamma)
FOXD1 forkhead box D1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FTO fat mass and obesity associated
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FUCA2 fucosidase, alpha-L- 2, plasma
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GBX2 gastrulation brain homeobox 2
GDNF glial cell derived neurotrophic factor
GGN gametogenetin
GLG1 golgi glycoprotein 1
GLIPR1L1 GLI pathogenesis-related 1 like 1
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPR156 G protein-coupled receptor 156
GPR89A G protein-coupled receptor 89A
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDAC9 histone deacetylase 9
HDGF hepatoma-derived growth factor
HEPHL1 hephaestin-like 1
HHLA3 HERV-H LTR-associating 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSDL1 hydroxysteroid dehydrogenase like 1
HSF2BP heat shock transcription factor 2 binding protein
HSPA2 heat shock 70kDa protein 2
HYI hydroxypyruvate isomerase (putative)
IQGAP3 IQ motif containing GTPase activating protein 3
IRF6 interferon regulatory factor 6
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
IVNS1ABP influenza virus NS1A binding protein
JRKL JRK-like
KAAG1 kidney associated antigen 1
KANK4 KN motif and ankyrin repeat domains 4
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCTD11 potassium channel tetramerization domain containing 11
KDM2A lysine (K)-specific demethylase 2A
KDM4D lysine (K)-specific demethylase 4D
KIAA1614 KIAA1614
KIF17 kinesin family member 17
KIF7 kinesin family member 7
KIFC3 kinesin family member C3
KLC2 kinesin light chain 2
KLF17 Kruppel-like factor 17
KLHL36 kelch-like family member 36
LAMA5 laminin, alpha 5
LAMB3 laminin, beta 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
LARP6 La ribonucleoprotein domain family, member 6
LDB1 LIM domain binding 1
LEMD1 LEM domain containing 1
LETM2 leucine zipper-EF-hand containing transmembrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIMA1 LIM domain and actin binding 1
LINC00113 long intergenic non-protein coding RNA 113
LIX1L Lix1 homolog (chicken) like
LOC646999 akirin 1 pseudogene
LONP2 lon peptidase 2, peroxisomal
LOXL2 lysyl oxidase-like 2
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRN4 leucine rich repeat neuronal 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAML2 mastermind-like 2 (Drosophila)
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MARVELD3 MARVEL domain containing 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED17 mediator complex subunit 17
MEX3D mex-3 RNA binding family member D
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MIEF2 mitochondrial elongation factor 2
MISP mitotic spindle positioning
MMP7 matrix metallopeptidase 7
MOB3A MOB kinase activator 3A
MR1 major histocompatibility complex, class I-related
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MSLN mesothelin
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTMR2 myotubularin related protein 2
MTSS1L metastasis suppressor 1-like
MUS81 MUS81 structure-specific endonuclease subunit
MYO3B myosin IIIB
MYO7B myosin VIIB
MYOF myoferlin
N4BP1 NEDD4 binding protein 1
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
NEK11 NIMA-related kinase 11
NME7 NME/NM23 family member 7
NNT nicotinamide nucleotide transhydrogenase
NOMO3 NODAL modulator 3
NPY4R neuropeptide Y receptor Y4
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRG4 neuregulin 4
NT5E 5'-nucleotidase, ecto (CD73)
NTF4 neurotrophin 4
NUDT16P1 nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1
OXCT1 3-oxoacid CoA transferase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP1 poly(A) binding protein interacting protein 1
PANX1 pannexin 1
PARN poly(A)-specific ribonuclease
PC pyruvate carboxylase
PCDHGA12 protocadherin gamma subfamily A, 12
PCED1B PC-esterase domain containing 1B
PDGFC platelet derived growth factor C
PEA15 phosphoprotein enriched in astrocytes 15
PEAR1 platelet endothelial aggregation receptor 1
PEX10 peroxisomal biogenesis factor 10
PHEX phosphate regulating endopeptidase homolog, X-linked
PICALM phosphatidylinositol binding clathrin assembly protein
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLCH2 phospholipase C, eta 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLSCR3 phospholipid scramblase 3
PNMAL1 paraneoplastic Ma antigen family-like 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCDBP protein kinase C, delta binding protein
PRSS23 protease, serine, 23
PSEN2 presenilin 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG2 pregnancy specific beta-1-glycoprotein 2
PSG4 pregnancy specific beta-1-glycoprotein 4
PSG6 pregnancy specific beta-1-glycoprotein 6
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PSG8 pregnancy specific beta-1-glycoprotein 8
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTRF polymerase I and transcript release factor
PXDC1 PX domain containing 1
PXN paxillin
PYGL phosphorylase, glycogen, liver
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB1B RAB1B, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RASD2 RASD family, member 2
RCE1 Ras converting CAAX endopeptidase 1
RELT RELT tumor necrosis factor receptor
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHOBTB2 Rho-related BTB domain containing 2
RIC8A RIC8 guanine nucleotide exchange factor A
RILPL1 Rab interacting lysosomal protein-like 1
RIN1 Ras and Rab interactor 1
RNF43 ring finger protein 43
RRAS related RAS viral (r-ras) oncogene homolog
RSPRY1 ring finger and SPRY domain containing 1
S100A10 S100 calcium binding protein A10
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERTAD4-AS1 SERTAD4 antisense RNA 1
SETD3 SET domain containing 3
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFTA1P surfactant associated 1, pseudogene
SFXN3 sideroflexin 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC35F3 solute carrier family 35, member F3
SLC38A4 solute carrier family 38, member 4
SLC38A5 solute carrier family 38, member 5
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLMO1 slowmo homolog 1 (Drosophila)
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMYD2 SET and MYND domain containing 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNORA11 small nucleolar RNA, H/ACA box 11
SNORA2B small nucleolar RNA, H/ACA box 2B
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA8 small nucleolar RNA, H/ACA box 8
SNORA84 small nucleolar RNA, H/ACA box 84
SNX33 sorting nexin 33
SPATA33 spermatogenesis associated 33
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SSH3 slingshot protein phosphatase 3
STAMBP STAM binding protein
STPG1 sperm-tail PG-rich repeat containing 1
SUCO SUN domain containing ossification factor
SUGT1P1 SUGT1 pseudogene 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT16 synaptotagmin XVI
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAGLN2 transgelin 2
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TARS threonyl-tRNA synthetase
TAT tyrosine aminotransferase
TBC1D28 TBC1 domain family, member 28
TBCK TBC1 domain containing kinase
TCP11L1 t-complex 11, testis-specific-like 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TEX2 testis expressed 2
THSD4 thrombospondin, type I, domain containing 4
TLDC1 TBC/LysM-associated domain containing 1
TLN2 talin 2
TMEM123 transmembrane protein 123
TMEM126A transmembrane protein 126A
TMEM126B transmembrane protein 126B
TMEM133 transmembrane protein 133
TMEM134 transmembrane protein 134
TMEM200B transmembrane protein 200B
TMEM244 transmembrane protein 244
TMPRSS7 transmembrane protease, serine 7
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM34 tripartite motif containing 34
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TSPAN10 tetraspanin 10
TTTY16 testis-specific transcript, Y-linked 16 (non-protein coding)
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBAP2L ubiquitin associated protein 2-like
UPK3B uroplakin 3B
USP10 ubiquitin specific peptidase 10
VAC14 Vac14 homolog (S. cerevisiae)
VEGFC vascular endothelial growth factor C
VIM vimentin
VIT vitrin
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VSIG1 V-set and immunoglobulin domain containing 1
VSTM5 V-set and transmembrane domain containing 5
WASF1 WAS protein family, member 1
WDR25 WD repeat domain 25
WDR59 WD repeat domain 59
WDR66 WD repeat domain 66
WWC2-AS2 WWC2 antisense RNA 2
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XYLT1 xylosyltransferase I
YAP1 Yes-associated protein 1
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YY1 YY1 transcription factor
ZBTB25 zinc finger and BTB domain containing 25
ZBTB4 zinc finger and BTB domain containing 4
ZDHHC7 zinc finger, DHHC-type containing 7
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZFP42 ZFP42 zinc finger protein
ZFP90 ZFP90 zinc finger protein
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF131 zinc finger protein 131
ZNF282 zinc finger protein 282
ZNF319 zinc finger protein 319
ZNF668 zinc finger protein 668
ZNF777 zinc finger protein 777
ZP1 zona pellucida glycoprotein 1 (sperm receptor)

low expression

Symbol Name
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
GPHN gephyrin
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
PAIP2 poly(A) binding protein interacting protein 2
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
UBE2E2 ubiquitin-conjugating enzyme E2E 2
USP16 ubiquitin specific peptidase 16
WDR55 WD repeat domain 55