Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5977-01A-11R-1686-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

435 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5977-01A-11R-1686-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ACE2 angiotensin I converting enzyme 2
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
AGTRAP angiotensin II receptor-associated protein
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AK2 adenylate kinase 2
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALYREF Aly/REF export factor
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae)
ANKRD13B ankyrin repeat domain 13B
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
AREG amphiregulin
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP39 Rho GTPase activating protein 39
ARMC6 armadillo repeat containing 6
ATG12 autophagy related 12
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B3GAT3 beta-1,3-glucuronyltransferase 3
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BDKRB2 bradykinin receptor B2
BEND3 BEN domain containing 3
C14ORF169 chromosome 14 open reading frame 169
C14ORF79 chromosome 14 open reading frame 79
C14ORF80 chromosome 14 open reading frame 80
C17ORF75 chromosome 17 open reading frame 75
C17ORF77 chromosome 17 open reading frame 77
C20ORF141 chromosome 20 open reading frame 141
C8ORF33 chromosome 8 open reading frame 33
C8ORF76 chromosome 8 open reading frame 76
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CANT1 calcium activated nucleotidase 1
CBX4 chromobox homolog 4
CCDC137 coiled-coil domain containing 137
CCDC43 coiled-coil domain containing 43
CCDC86 coiled-coil domain containing 86
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCNK cyclin K
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CD47 CD47 molecule
CD70 CD70 molecule
CDC25B cell division cycle 25B
CDC27 cell division cycle 27
CDV3 CDV3 homolog (mouse)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEP170B centrosomal protein 170B
CHRAC1 chromatin accessibility complex 1
CLCF1 cardiotrophin-like cytokine factor 1
CLEC1B C-type lectin domain family 1, member B
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNBP CCHC-type zinc finger, nucleic acid binding protein
COA7 cytochrome c oxidase assembly factor 7 (putative)
COMMD5 COMM domain containing 5
COPG1 coatomer protein complex, subunit gamma 1
COPS5 COP9 signalosome subunit 5
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP2 cysteine-rich protein 2
CRYBA1 crystallin, beta A1
CSNK1D casein kinase 1, delta
CSPP1 centrosome and spindle pole associated protein 1
CTU1 cytosolic thiouridylase subunit 1
CXCR1 chemokine (C-X-C motif) receptor 1
CXORF23 chromosome X open reading frame 23
CYB561A3 cytochrome b561 family, member A3
CYC1 cytochrome c-1
DAOA D-amino acid oxidase activator
DAZAP1 DAZ associated protein 1
DCAF10 DDB1 and CUL4 associated factor 10
DCAF13 DDB1 and CUL4 associated factor 13
DCAF15 DDB1 and CUL4 associated factor 15
DCAF4 DDB1 and CUL4 associated factor 4
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEDD2 death effector domain containing 2
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DIO3 deiodinase, iodothyronine, type III
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DOHH deoxyhypusine hydroxylase/monooxygenase
DPP6 dipeptidyl-peptidase 6
DVL1 dishevelled segment polarity protein 1
DYNLL2 dynein, light chain, LC8-type 2
EBAG9 estrogen receptor binding site associated, antigen, 9
EBNA1BP2 EBNA1 binding protein 2
ECE2 endothelin converting enzyme 2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF4A3 eukaryotic translation initiation factor 4A3
EIF5A2 eukaryotic translation initiation factor 5A2
EIF5AL1 eukaryotic translation initiation factor 5A-like 1
ELAC2 elaC ribonuclease Z 2
EMC2 ER membrane protein complex subunit 2
ENO1 enolase 1, (alpha)
ENY2 enhancer of yellow 2 homolog (Drosophila)
EPPK1 epiplakin 1
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERF Ets2 repressor factor
ERH enhancer of rudimentary homolog (Drosophila)
EXOSC6 exosome component 6
EXT1 exostosin glycosyltransferase 1
FADD Fas (TNFRSF6)-associated via death domain
FAM138F family with sequence similarity 138, member F
FAM49B family with sequence similarity 49, member B
FAM83H family with sequence similarity 83, member H
FAM91A1 family with sequence similarity 91, member A1
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FBXL19 F-box and leucine-rich repeat protein 19
FJX1 four jointed box 1 (Drosophila)
FKRP fukutin related protein
FOXF2 forkhead box F2
FOXK2 forkhead box K2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FTSJ3 FtsJ homolog 3 (E. coli)
GAL galanin/GMAP prepropeptide
GAR1 GAR1 ribonucleoprotein
GATA2 GATA binding protein 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCSH glycine cleavage system protein H (aminomethyl carrier)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJB3 gap junction protein, beta 3, 31kDa
GLRX5 glutaredoxin 5
GMPR2 guanosine monophosphate reductase 2
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GOLGA5 golgin A5
GOSR1 golgi SNAP receptor complex member 1
GPATCH3 G patch domain containing 3
GPR68 G protein-coupled receptor 68
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRWD1 glutamate-rich WD repeat containing 1
GSK3A glycogen synthase kinase 3 alpha
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HDGF hepatoma-derived growth factor
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HES4 hes family bHLH transcription factor 4
HES7 hes family bHLH transcription factor 7
HLA-H major histocompatibility complex, class I, H (pseudogene)
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HRSP12 heat-responsive protein 12
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IER5L immediate early response 5-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNA14 interferon, alpha 14
IFNA8 interferon, alpha 8
IL4R interleukin 4 receptor
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
INTS12 integrator complex subunit 12
IPO4 importin 4
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KHNYN KH and NYN domain containing
KIAA1429 KIAA1429
KIF18B kinesin family member 18B
KLF16 Kruppel-like factor 16
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae)
LDHA lactate dehydrogenase A
LGALS9B lectin, galactoside-binding, soluble, 9B
LIAS lipoic acid synthetase
LINC00052 long intergenic non-protein coding RNA 52
LINC00515 long intergenic non-protein coding RNA 515
LOC286094
LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LRR1 leucine rich repeat protein 1
LRRC14 leucine rich repeat containing 14
LRRC19 leucine rich repeat containing 19
LRRC41 leucine rich repeat containing 41
LRRC59 leucine rich repeat containing 59
LSM12 LSM12 homolog (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
LY6K lymphocyte antigen 6 complex, locus K
LYAR Ly1 antibody reactive
MAEA macrophage erythroblast attacher
MAF1 MAF1 homolog (S. cerevisiae)
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARK3 MAP/microtubule affinity-regulating kinase 3
MCTS2P malignant T cell amplified sequence 2, pseudogene
MDFI MyoD family inhibitor
MED30 mediator complex subunit 30
MED6 mediator complex subunit 6
MGC16275 uncharacterized protein MGC16275
MIB2 mindbomb E3 ubiquitin protein ligase 2
MIER2 mesoderm induction early response 1, family member 2
MINA MYC induced nuclear antigen
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPL10 mitochondrial ribosomal protein L10
MRPL15 mitochondrial ribosomal protein L15
MRPL3 mitochondrial ribosomal protein L3
MRPS23 mitochondrial ribosomal protein S23
MRRF mitochondrial ribosome recycling factor
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
MTDH metadherin
MTERF3 mitochondrial transcription termination factor 3
MTFR1 mitochondrial fission regulator 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBBP1A MYB binding protein (P160) 1a
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO7B myosin VIIB
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAGS N-acetylglutamate synthase
NCL nucleolin
NCLN nicalin
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NEK11 NIMA-related kinase 11
NELFB negative elongation factor complex member B
NGDN neuroguidin, EIF4E binding protein
NINJ2 ninjurin 2
NLE1 notchless homolog 1 (Drosophila)
NMT1 N-myristoyltransferase 1
NOL11 nucleolar protein 11
NOL9 nucleolar protein 9
NOP14 NOP14 nucleolar protein
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSRP1 nuclear speckle splicing regulatory protein 1
NUDCD1 NudC domain containing 1
NXT1 nuclear transport factor 2-like export factor 1
OASL 2'-5'-oligoadenylate synthetase-like
OR10A2 olfactory receptor, family 10, subfamily A, member 2
ORAOV1 oral cancer overexpressed 1
OTUD6B OTU domain containing 6B
P3H2 prolyl 3-hydroxylase 2
PABPN1 poly(A) binding protein, nuclear 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PCNXL4 pecanex-like 4 (Drosophila)
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEC plectin
PLSCR1 phospholipid scramblase 1
PLXNA1 plexin A1
PNPO pyridoxamine 5'-phosphate oxidase
POMT2 protein-O-mannosyltransferase 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRDX4 peroxiredoxin 4
PRMT5 protein arginine methyltransferase 5
PRPF19 pre-mRNA processing factor 19
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTBP1 polypyrimidine tract binding protein 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PUF60 poly-U binding splicing factor 60KDa
PYCRL pyrroline-5-carboxylate reductase-like
PYGL phosphorylase, glycogen, liver
QSOX2 quiescin Q6 sulfhydryl oxidase 2
R3HDM4 R3H domain containing 4
RAB7A RAB7A, member RAS oncogene family
RASIP1 Ras interacting protein 1
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RBBP7 retinoblastoma binding protein 7
RBM28 RNA binding motif protein 28
RCC1 regulator of chromosome condensation 1
RETNLB resistin like beta
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
RGS20 regulator of G-protein signaling 20
RIPK2 receptor-interacting serine-threonine kinase 2
RMDN1 regulator of microtubule dynamics 1
RNF126 ring finger protein 126
RNF139 ring finger protein 139
RNF151 ring finger protein 151
RPL7 ribosomal protein L7
RPN1 ribophorin I
RPTOR regulatory associated protein of MTOR, complex 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
SAFB scaffold attachment factor B
SAFB2 scaffold attachment factor B2
SCARNA9L small Cajal body-specific RNA 9-like
SCFD1 sec1 family domain containing 1
SCRIB scribbled planar cell polarity protein
SCX scleraxis basic helix-loop-helix transcription factor
SDCCAG3 serologically defined colon cancer antigen 3
SDHAF2 succinate dehydrogenase complex assembly factor 2
SERP1 stress-associated endoplasmic reticulum protein 1
SF1 splicing factor 1
SH3KBP1 SH3-domain kinase binding protein 1
SHARPIN SHANK-associated RH domain interactor
SIGMAR1 sigma non-opioid intracellular receptor 1
SIX5 SIX homeobox 5
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC35G5 solute carrier family 35, member G5
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13
SLFN5 schlafen family member 5
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG8 SMG8 nonsense mediated mRNA decay factor
SMS spermine synthase
SNAI2 snail family zinc finger 2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNORA24 small nucleolar RNA, H/ACA box 24
SNORD97 small nucleolar RNA, C/D box 97
SNW1 SNW domain containing 1
SP6 Sp6 transcription factor
SP8 Sp8 transcription factor
SPAG9 sperm associated antigen 9
SRM spermidine synthase
SRSF2 serine/arginine-rich splicing factor 2
STK11 serine/threonine kinase 11
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
SYAP1 synapse associated protein 1
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TBC1D3F TBC1 domain family, member 3F
TBX18 T-box 18
TCEA1 transcription elongation factor A (SII), 1
TFG TRK-fused gene
TGS1 trimethylguanosine synthase 1
TIGD5 tigger transposable element derived 5
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TKFC triokinase/FMN cyclase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK2 tousled-like kinase 2
TM9SF1 transmembrane 9 superfamily member 1
TMCC1 transmembrane and coiled-coil domain family 1
TMED6 transmembrane emp24 protein transport domain containing 6
TMEM109 transmembrane protein 109
TMEM132A transmembrane protein 132A
TMEM138 transmembrane protein 138
TMEM177 transmembrane protein 177
TMEM200B transmembrane protein 200B
TMEM216 transmembrane protein 216
TMEM259 transmembrane protein 259
TMEM55B transmembrane protein 55B
TMEM67 transmembrane protein 67
TMEM70 transmembrane protein 70
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNS4 tensin 4
TOR4A torsin family 4, member A
TPGS1 tubulin polyglutamylase complex subunit 1
TRMT61A tRNA methyltransferase 61A
TTC4 tetratricopeptide repeat domain 4
TTTY16 testis-specific transcript, Y-linked 16 (non-protein coding)
TUBB3 tubulin, beta 3 class III
TUBG1 tubulin, gamma 1
TUSC1 tumor suppressor candidate 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
U2AF2 U2 small nuclear RNA auxiliary factor 2
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBA5 ubiquitin-like modifier activating enzyme 5
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2Z ubiquitin-conjugating enzyme E2Z
UBQLN1 ubiquilin 1
UCA1 urothelial cancer associated 1 (non-protein coding)
UMPS uridine monophosphate synthetase
USP36 ubiquitin specific peptidase 36
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VCPKMT valosin containing protein lysine (K) methyltransferase
VEGFC vascular endothelial growth factor C
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WISP3 WNT1 inducible signaling pathway protein 3
XPO6 exportin 6
YTHDC1 YTH domain containing 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZBTB32 zinc finger and BTB domain containing 32
ZC3H14 zinc finger CCCH-type containing 14
ZC3H3 zinc finger CCCH-type containing 3
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFAT-AS1 ZFAT antisense RNA 1
ZFP41 ZFP41 zinc finger protein
ZNF16 zinc finger protein 16
ZNF250 zinc finger protein 250
ZNF410 zinc finger protein 410
ZNF517 zinc finger protein 517
ZNF572 zinc finger protein 572
ZNF574 zinc finger protein 574
ZNF628 zinc finger protein 628
ZNF645 zinc finger protein 645
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZNF707 zinc finger protein 707
ZNF787 zinc finger protein 787
ZSCAN5A zinc finger and SCAN domain containing 5A

low expression

Symbol Name
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CSDE1 cold shock domain containing E1, RNA-binding
CTTNBP2NL CTTNBP2 N-terminal like
DSCR3 Down syndrome critical region 3
ECD ecdysoneless homolog (Drosophila)
KLHL26 kelch-like family member 26
PRPF18 pre-mRNA processing factor 18
RAP1A RAP1A, member of RAS oncogene family
RSBN1 round spermatid basic protein 1
SEPHS1 selenophosphate synthetase 1
SIKE1 suppressor of IKBKE 1
SNX1 sorting nexin 1
TRIM33 tripartite motif containing 33