Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

382 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM29 ADAM metallopeptidase domain 29
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADORA3 adenosine A3 receptor
AFF4 AF4/FMR2 family, member 4
AKAP11 A kinase (PRKA) anchor protein 11
AKAP5 A kinase (PRKA) anchor protein 5
AKNA AT-hook transcription factor
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15B arachidonate 15-lipoxygenase, type B
ALOXE3 arachidonate lipoxygenase 3
ANGPT2 angiopoietin 2
ANKRD31 ankyrin repeat domain 31
ANKRD44 ankyrin repeat domain 44
AOAH acyloxyacyl hydrolase (neutrophil)
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARHGAP30 Rho GTPase activating protein 30
AVPR1A arginine vasopressin receptor 1A
BCO1 beta-carotene oxygenase 1
BCO2 beta-carotene oxygenase 2
BMP2K BMP2 inducible kinase
BTBD9 BTB (POZ) domain containing 9
BTLA B and T lymphocyte associated
C1ORF68 chromosome 1 open reading frame 68
C5ORF47 chromosome 5 open reading frame 47
CASS4 Cas scaffolding protein family member 4
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD101 CD101 molecule
CD163L1 CD163 molecule-like 1
CD2 CD2 molecule
CD226 CD226 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD5 CD5 molecule
CD6 CD6 molecule
CD7 CD7 molecule
CD84 CD84 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CD96 CD96 molecule
CDKL5 cyclin-dependent kinase-like 5
CDSN corneodesmosin
CECR1 cat eye syndrome chromosome region, candidate 1
CFHR1 complement factor H-related 1
CHL1 cell adhesion molecule L1-like
CLDN17 claudin 17
CLEC6A C-type lectin domain family 6, member A
CMKLR1 chemerin chemokine-like receptor 1
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPNE5 copine V
CRYGS crystallin, gamma S
CSF1R colony stimulating factor 1 receptor
CST7 cystatin F (leukocystatin)
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR6 chemokine (C-X-C motif) receptor 6
CYTIP cytohesin 1 interacting protein
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEFB103B defensin, beta 103B
DENND1B DENN/MADD domain containing 1B
DIO2 deiodinase, iodothyronine, type II
DLX3 distal-less homeobox 3
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DRD3 dopamine receptor D3
DSC2 desmocollin 2
EAF1 ELL associated factor 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EOMES eomesodermin
EP300 E1A binding protein p300
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPGN epithelial mitogen
EPN3 epsin 3
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ESYT3 extended synaptotagmin-like protein 3
EVI2B ecotropic viral integration site 2B
EXOC6B exocyst complex component 6B
EXOC8 exocyst complex component 8
FAM124B family with sequence similarity 124B
FAM160B1 family with sequence similarity 160, member B1
FAM162B family with sequence similarity 162, member B
FAM196B family with sequence similarity 196, member B
FAM214A family with sequence similarity 214, member A
FAM46C family with sequence similarity 46, member C
FAM78A family with sequence similarity 78, member A
FAM83G family with sequence similarity 83, member G
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCHSD1 FCH and double SH3 domains 1
FCRL5 Fc receptor-like 5
FER fer (fps/fes related) tyrosine kinase
FER1L6 fer-1-like family member 6
FGL2 fibrinogen-like 2
FICD FIC domain containing
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FNBP1 formin binding protein 1
FOLH1B folate hydrolase 1B
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FPR3 formyl peptide receptor 3
FUCA1 fucosidase, alpha-L- 1, tissue
GAB1 GRB2-associated binding protein 1
GH1 growth hormone 1
GIGYF2 GRB10 interacting GYF protein 2
GIMAP6 GTPase, IMAP family member 6
GIMAP8 GTPase, IMAP family member 8
GLIPR1 GLI pathogenesis-related 1
GPR15 G protein-coupled receptor 15
GPR171 G protein-coupled receptor 171
GPR174 G protein-coupled receptor 174
GPR34 G protein-coupled receptor 34
GPR55 G protein-coupled receptor 55
GPR82 G protein-coupled receptor 82
GPRIN3 GPRIN family member 3
GRAP2 GRB2-related adaptor protein 2
GREM1 gremlin 1, DAN family BMP antagonist
GSC2 goosecoid homeobox 2
GSDMA gasdermin A
GVINP1 GTPase, very large interferon inducible pseudogene 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIPK3 homeodomain interacting protein kinase 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HMOX1 heme oxygenase 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTT huntingtin
ICAM3 intercellular adhesion molecule 3
IDE insulin-degrading enzyme
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL16 interleukin 16
IL21 interleukin 21
IL2RB interleukin 2 receptor, beta
IL36RN interleukin 36 receptor antagonist
IL5RA interleukin 5 receptor, alpha
IL7R interleukin 7 receptor
IL9R interleukin 9 receptor
INO80D INO80 complex subunit D
IP6K1 inositol hexakisphosphate kinase 1
IPCEF1 interaction protein for cytohesin exchange factors 1
IRF4 interferon regulatory factor 4
ITGA1 integrin, alpha 1
ITGA8 integrin, alpha 8
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIF21B kinesin family member 21B
KLHL18 kelch-like family member 18
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KPRP keratinocyte proline-rich protein
KRT2 keratin 2, type II
KRT24 keratin 24, type I
KRT27 keratin 27, type I
KRT37 keratin 37, type I
KRT80 keratin 80, type II
LAX1 lymphocyte transmembrane adaptor 1
LCE1A late cornified envelope 1A
LCE1F late cornified envelope 1F
LCE2A late cornified envelope 2A
LCE2B late cornified envelope 2B
LCE2C late cornified envelope 2C
LCE2D late cornified envelope 2D
LCE3A late cornified envelope 3A
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LCE3D late cornified envelope 3D
LCE3E late cornified envelope 3E
LCE6A late cornified envelope 6A
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LHX4 LIM homeobox 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINC00293 long intergenic non-protein coding RNA 293
LIPK lipase, family member K
LNPEP leucyl/cystinyl aminopeptidase
LOC284441 actin-related protein 2 pseudogene
LOC285627 uncharacterized LOC285627
LPPR4 lipid phosphate phosphatase-related protein type 4
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRRN3 leucine rich repeat neuronal 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
LY9 lymphocyte antigen 9
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3
LYST lysosomal trafficking regulator
MALT1 MALT1 paracaspase
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MBD1 methyl-CpG binding domain protein 1
MC4R melanocortin 4 receptor
MCTP1 multiple C2 domains, transmembrane 1
MFAP3 microfibrillar-associated protein 3
MPEG1 macrophage expressed 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPZL3 myelin protein zero-like 3
MRGPRX2 MAS-related GPR, member X2
MTF1 metal-regulatory transcription factor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX2 MX dynamin-like GTPase 2
MYD88 myeloid differentiation primary response 88
MYO1E myosin IE
NAIP NLR family, apoptosis inhibitory protein
NCKAP1L NCK-associated protein 1-like
NCR1 natural cytotoxicity triggering receptor 1
NEU2 sialidase 2 (cytosolic sialidase)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NIPAL1 NIPA-like domain containing 1
NLGN4X neuroligin 4, X-linked
NLRC3 NLR family, CARD domain containing 3
NOP9 NOP9 nucleolar protein
NUGGC nuclear GTPase, germinal center associated
NWD2 NACHT and WD repeat domain containing 2
OCLN occludin
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR14I1 olfactory receptor, family 14, subfamily I, member 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)
OR2M3 olfactory receptor, family 2, subfamily M, member 3
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OR6K3 olfactory receptor, family 6, subfamily K, member 3
OR6M1 olfactory receptor, family 6, subfamily M, member 1
OR7D2 olfactory receptor, family 7, subfamily D, member 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PBRM1 polybromo 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDCD6IP programmed cell death 6 interacting protein
PDE12 phosphodiesterase 12
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PEAK1 pseudopodium-enriched atypical kinase 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G4E phospholipase A2, group IVE
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRDM1 PR domain containing 1, with ZNF domain
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRF1 perforin 1 (pore forming protein)
PROX2 prospero homeobox 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PURA purine-rich element binding protein A
PYHIN1 pyrin and HIN domain family, member 1
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB5A RAB5A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASGRP4 RAS guanyl releasing protein 4
RBM12 RNA binding motif protein 12
REG4 regenerating islet-derived family, member 4
RELN reelin
RGS5 regulator of G-protein signaling 5
RHBDD1 rhomboid domain containing 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE7 ribonuclease, RNase A family, 7
SAMHD1 SAM domain and HD domain 1
SCGB1C1 secretoglobin, family 1C, member 1
SEC24A SEC24 family member A
SECISBP2L SECIS binding protein 2-like
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELPLG selectin P ligand
SEPT8 septin 8
SERINC5 serine incorporator 5
SFMBT2 Scm-like with four mbt domains 2
SGK223 homolog of rat pragma of Rnd2
SH2D1A SH2 domain containing 1A
SH3BP5L SH3-binding domain protein 5-like
SIRPB1 signal-regulatory protein beta 1
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLFN12 schlafen family member 12
SLFN5 schlafen family member 5
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SNRK SNF related kinase
SNX20 sorting nexin 20
SPAG17 sperm associated antigen 17
SPATA13 spermatogenesis associated 13
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPN sialophorin
SPRED1 sprouty-related, EVH1 domain containing 1
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2G small proline-rich protein 2G
SPRY4 sprouty homolog 4 (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAB1 stabilin 1
STK17B serine/threonine kinase 17b
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STXBP5 syntaxin binding protein 5 (tomosyn)
SUCNR1 succinate receptor 1
TAGAP T-cell activation RhoGTPase activating protein
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TBXAS1 thromboxane A synthase 1 (platelet)
TGM3 transglutaminase 3
TGM5 transglutaminase 5
TGM6 transglutaminase 6
THEMIS thymocyte selection associated
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLE3 transducin-like enhancer of split 3
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMEM236 transmembrane protein 236
TMEM86A transmembrane protein 86A
TP53INP1 tumor protein p53 inducible nuclear protein 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIML1 tripartite motif family-like 1
TRIP12 thyroid hormone receptor interactor 12
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSPYL1 TSPY-like 1
TTTY4C testis-specific transcript, Y-linked 4C (non-protein coding)
TXK TXK tyrosine kinase
UBA7 ubiquitin-like modifier activating enzyme 7
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2J1 ubiquitin-conjugating enzyme E2, J1
USP38 ubiquitin specific peptidase 38
USP9X ubiquitin specific peptidase 9, X-linked
VCL vinculin
VIPR1 vasoactive intestinal peptide receptor 1
VSIG8 V-set and immunoglobulin domain containing 8
VWF von Willebrand factor
WDFY1 WD repeat and FYVE domain containing 1
WDFY4 WDFY family member 4
WIPF1 WAS/WASL interacting protein family, member 1
XCR1 chemokine (C motif) receptor 1
XRN1 5'-3' exoribonuclease 1
YOD1 YOD1 deubiquitinase
ZNF366 zinc finger protein 366
ZNF407 zinc finger protein 407
ZNF426 zinc finger protein 426
ZNF654 zinc finger protein 654
ZNF770 zinc finger protein 770
ZNF800 zinc finger protein 800
ZNF831 zinc finger protein 831
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1