Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

376 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAT1 adenosine deaminase, tRNA-specific 1
ADCY1 adenylate cyclase 1 (brain)
ADCY7 adenylate cyclase 7
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRE2 adhesion G protein-coupled receptor E2
AGPS alkylglycerone phosphate synthase
AHNAK2 AHNAK nucleoprotein 2
AIM1 absent in melanoma 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP11 A kinase (PRKA) anchor protein 11
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ANGEL1 angel homolog 1 (Drosophila)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APH1B APH1B gamma secretase subunit
AQR aquarius intron-binding spliceosomal factor
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP5 Rho GTPase activating protein 5
ARPIN actin-related protein 2/3 complex inhibitor
ARRDC4 arrestin domain containing 4
ASCC3 activating signal cointegrator 1 complex subunit 3
ATF7IP activating transcription factor 7 interacting protein
ATG2B autophagy related 2B
ATP10D ATPase, class V, type 10D
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AVL9 AVL9 homolog (S. cerevisiase)
AVPR1A arginine vasopressin receptor 1A
BBS9 Bardet-Biedl syndrome 9
BMP2K BMP2 inducible kinase
BRAT1 BRCA1-associated ATM activator 1
BTBD7 BTB (POZ) domain containing 7
C14ORF169 chromosome 14 open reading frame 169
C16ORF62 chromosome 16 open reading frame 62
C17ORF51 chromosome 17 open reading frame 51
C7ORF31 chromosome 7 open reading frame 31
C9ORF129 chromosome 9 open reading frame 129
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC85C coiled-coil domain containing 85C
CCL1 chemokine (C-C motif) ligand 1
CCL24 chemokine (C-C motif) ligand 24
CD163L1 CD163 molecule-like 1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDCA7L cell division cycle associated 7-like
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDHR1 cadherin-related family member 1
CDK13 cyclin-dependent kinase 13
CDK15 cyclin-dependent kinase 15
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHN2 chimerin 2
CHSY3 chondroitin sulfate synthase 3
CHURC1 churchill domain containing 1
CKAP2 cytoskeleton associated protein 2
CLC Charcot-Leyden crystal galectin
CLCA2 chloride channel accessory 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMA1 chymase 1, mast cell
COA7 cytochrome c oxidase assembly factor 7 (putative)
COG8 component of oligomeric golgi complex 8
COL4A1 collagen, type IV, alpha 1
COL6A5 collagen, type VI, alpha 5
CPA3 carboxypeptidase A3 (mast cell)
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPVL carboxypeptidase, vitellogenic-like
CSNK1G1 casein kinase 1, gamma 1
CTSG cathepsin G
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYB561D1 cytochrome b561 family, member D1
CYCS cytochrome c, somatic
CYTH3 cytohesin 3
DAGLB diacylglycerol lipase, beta
DCAF4 DDB1 and CUL4 associated factor 4
DCTN1 dynactin 1
DCTN4 dynactin 4 (p62)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DICER1 dicer 1, ribonuclease type III
DISP2 dispatched homolog 2 (Drosophila)
DLEU7 deleted in lymphocytic leukemia, 7
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DOCK11 dedicator of cytokinesis 11
DPY19L1 dpy-19-like 1 (C. elegans)
DSG1 desmoglein 1
DSP desmoplakin
DUOX1 dual oxidase 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF5 eukaryotic translation initiation factor 5
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EML1 echinoderm microtubule associated protein like 1
EML5 echinoderm microtubule associated protein like 5
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
ESYT1 extended synaptotagmin-like protein 1
EXOC5 exocyst complex component 5
EXOC6B exocyst complex component 6B
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM120B family with sequence similarity 120B
FAM126A family with sequence similarity 126, member A
FAM188B family with sequence similarity 188, member B
FAM63B family with sequence similarity 63, member B
FAM84A family with sequence similarity 84, member A
FAM98A family with sequence similarity 98, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FAT2 FAT atypical cadherin 2
FBXL18 F-box and leucine-rich repeat protein 18
FKBP14 FK506 binding protein 14, 22 kDa
FKBP9 FK506 binding protein 9, 63 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FNTB farnesyltransferase, CAAX box, beta
FOXN3 forkhead box N3
FRMD6 FERM domain containing 6
FSCN1 fascin actin-bundling protein 1
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
GALC galactosylceramidase
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCSAML germinal center-associated, signaling and motility-like
GEMIN5 gem (nuclear organelle) associated protein 5
GJA1 gap junction protein, alpha 1, 43kDa
GJA3 gap junction protein, alpha 3, 46kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLI3 GLI family zinc finger 3
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH11 G patch domain containing 11
GPR135 G protein-coupled receptor 135
GPR176 G protein-coupled receptor 176
GPR21 G protein-coupled receptor 21
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDC histidine decarboxylase
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERPUD2 HERPUD family member 2
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOMER1 homer scaffolding protein 1
HOXA1 homeobox A1
HOXA4 homeobox A4
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
IGF2R insulin-like growth factor 2 receptor
IGSF3 immunoglobulin superfamily, member 3
IL13RA1 interleukin 13 receptor, alpha 1
INTS1 integrator complex subunit 1
INTS5 integrator complex subunit 5
IQGAP1 IQ motif containing GTPase activating protein 1
ISPD isoprenoid synthase domain containing
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNK10 potassium channel, two pore domain subfamily K, member 10
KHNYN KH and NYN domain containing
KIAA0100 KIAA0100
KIAA0319L KIAA0319-like
KIAA0391 KIAA0391
KIAA0586 KIAA0586
KIAA1715 KIAA1715
KIAA1919 KIAA1919
KIDINS220 kinase D-interacting substrate, 220kDa
KIRREL kin of IRRE like (Drosophila)
KLHL4 kelch-like family member 4
KLHL7 kelch-like family member 7
KTN1 kinectin 1 (kinesin receptor)
LACE1 lactation elevated 1
LATS1 large tumor suppressor kinase 1
LINC01550 long intergenic non-protein coding RNA 1550
LMBRD2 LMBR1 domain containing 2
LOC154761 family with sequence similarity 115, member C pseudogene
LOC284441 actin-related protein 2 pseudogene
LOC90784 uncharacterized LOC90784
LPAR3 lysophosphatidic acid receptor 3
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRK1 leucine-rich repeat kinase 1
LTB4R leukotriene B4 receptor
LTBP1 latent transforming growth factor beta binding protein 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN2A1 mannosidase, alpha, class 2A, member 1
MANEA mannosidase, endo-alpha
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARVELD1 MARVEL domain containing 1
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MBNL3 muscleblind-like splicing regulator 3
MCM9 minichromosome maintenance complex component 9
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO1D myosin ID
MYO9A myosin IXA
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAV1 neuron navigator 1
NDC1 NDC1 transmembrane nucleoporin
NEK9 NIMA-related kinase 9
NELL2 NEL-like 2 (chicken)
NEMF nuclear export mediator factor
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NID1 nidogen 1
NIN ninein (GSK3B interacting protein)
NIPAL4 NIPA-like domain containing 4
NOD1 nucleotide-binding oligomerization domain containing 1
NOL6 nucleolar protein 6 (RNA-associated)
NOP9 NOP9 nucleolar protein
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NSG1 neuron specific gene family member 1
NSUN4 NOP2/Sun domain family, member 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUBPL nucleotide binding protein-like
NUDCD3 NudC domain containing 3
NUP160 nucleoporin 160kDa
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR10G2 olfactory receptor, family 10, subfamily G, member 2
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHB11 protocadherin beta 11
PCDHB12 protocadherin beta 12
PCDHB19P protocadherin beta 19 pseudogene
PCDHB2 protocadherin beta 2
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGB7 protocadherin gamma subfamily B, 7
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC5 protocadherin gamma subfamily C, 5
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PHF14 PHD finger protein 14
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1
PLK2 polo-like kinase 2
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POU4F3 POU class 4 homeobox 3
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSEN1 presenilin 1
PSKH1 protein serine kinase H1
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTGDR2 prostaglandin D2 receptor 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PURB purine-rich element binding protein B
PXDNL peroxidasin-like
RBM15 RNA binding motif protein 15
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RIN3 Ras and Rab interactor 3
RNF216 ring finger protein 216
RNF31 ring finger protein 31
RSPH3 radial spoke 3 homolog (Chlamydomonas)
SCAMP4 secretory carrier membrane protein 4
SCFD2 sec1 family domain containing 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEC23A Sec23 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT7 septin 7
SERBP1 SERPINE1 mRNA binding protein 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2D7 SH2 domain containing 7
SIGLEC17P sialic acid binding Ig-like lectin 17, pseudogene
SIGLEC6 sialic acid binding Ig-like lectin 6
SKAP2 src kinase associated phosphoprotein 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A6 solute carrier family 30 (zinc transporter), member 6
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35F6 solute carrier family 35, member F6
SLC38A7 solute carrier family 38, member 7
SLC38A9 solute carrier family 38, member 9
SLC39A9 solute carrier family 39, member 9
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC45A3 solute carrier family 45, member 3
SLFN12 schlafen family member 12
SLFN5 schlafen family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG6 SMG6 nonsense mediated mRNA decay factor
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX10 sorting nexin 10
SNX13 sorting nexin 13
SNX29 sorting nexin 29
SNX6 sorting nexin 6
SOCS4 suppressor of cytokine signaling 4
SP3 Sp3 transcription factor
SPRED3 sprouty-related, EVH1 domain containing 3
STK31 serine/threonine kinase 31
STRIP1 striatin interacting protein 1
STXBP5 syntaxin binding protein 5 (tomosyn)
STYX serine/threonine/tyrosine interacting protein
SULF2 sulfatase 2
SUSD1 sushi domain containing 1
SYNJ2 synaptojanin 2
TBC1D2B TBC1 domain family, member 2B
TBRG4 transforming growth factor beta regulator 4
TDP1 tyrosyl-DNA phosphodiesterase 1
TECPR2 tectonin beta-propeller repeat containing 2
TENM2 teneurin transmembrane protein 2
TEP1 telomerase-associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TLR6 toll-like receptor 6
TM9SF1 transmembrane 9 superfamily member 1
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMED8 transmembrane emp24 protein transport domain containing 8
TMEM106B transmembrane protein 106B
TMEM181 transmembrane protein 181
TMX1 thioredoxin-related transmembrane protein 1
TNRC18 trinucleotide repeat containing 18
TPSB2 tryptase beta 2 (gene/pseudogene)
TPSD1 tryptase delta 1
TRIM58 tripartite motif containing 58
TRIM6 tripartite motif containing 6
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIP11 thyroid hormone receptor interactor 11
TSPYL1 TSPY-like 1
TSSK1B testis-specific serine kinase 1B
TTC30B tetratricopeptide repeat domain 30B
TTYH3 tweety family member 3
TUBA4B tubulin, alpha 4b
TUBAL3 tubulin, alpha-like 3
TWISTNB TWIST neighbor
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UEVLD UEV and lactate/malate dehyrogenase domains
URGCP upregulator of cell proliferation
USP42 ubiquitin specific peptidase 42
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VANGL1 VANGL planar cell polarity protein 1
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
WISP3 WNT1 inducible signaling pathway protein 3
XPO4 exportin 4
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YLPM1 YLP motif containing 1
ZBED9 zinc finger, BED-type containing 9
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
ZC4H2 zinc finger, C4H2 domain containing
ZCCHC5 zinc finger, CCHC domain containing 5
ZDHHC5 zinc finger, DHHC-type containing 5
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZFYVE1 zinc finger, FYVE domain containing 1
ZFYVE26 zinc finger, FYVE domain containing 26
ZHX3 zinc fingers and homeoboxes 3
ZMPSTE24 zinc metallopeptidase STE24
ZNF12 zinc finger protein 12
ZNF770 zinc finger protein 770
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZSWIM5 zinc finger, SWIM-type containing 5

low expression

Symbol Name
BSDC1 BSD domain containing 1
ZC3H15 zinc finger CCCH-type containing 15