Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

391 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACLY ATP citrate lyase
ACPT acid phosphatase, testicular
ACTBL2 actin, beta-like 2
ADAM20 ADAM metallopeptidase domain 20
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY7 adenylate cyclase 7
ADGRG3 adhesion G protein-coupled receptor G3
AEN apoptosis enhancing nuclease
AGO2 argonaute RISC catalytic component 2
AKAP8 A kinase (PRKA) anchor protein 8
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
AMER1 APC membrane recruitment protein 1
AMIGO2 adhesion molecule with Ig-like domain 2
AMPD2 adenosine monophosphate deaminase 2
ANAPC1 anaphase promoting complex subunit 1
ANKRD34C ankyrin repeat domain 34C
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQR aquarius intron-binding spliceosomal factor
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMC1 armadillo repeat containing 1
ARSJ arylsulfatase family, member J
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP13A1 ATPase type 13A1
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
BAHCC1 BAH domain and coiled-coil containing 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BEND2 BEN domain containing 2
BEND3 BEN domain containing 3
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BTNL8 butyrophilin-like 8
C10ORF2 chromosome 10 open reading frame 2
C10ORF82 chromosome 10 open reading frame 82
C14ORF169 chromosome 14 open reading frame 169
C15ORF39 chromosome 15 open reading frame 39
C16ORF87 chromosome 16 open reading frame 87
C22ORF34 chromosome 22 open reading frame 34
C4ORF32 chromosome 4 open reading frame 32
C6ORF120 chromosome 6 open reading frame 120
C6ORF15 chromosome 6 open reading frame 15
C7ORF33 chromosome 7 open reading frame 33
C7ORF71 chromosome 7 open reading frame 71
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALB1 calbindin 1, 28kDa
CALN1 calneuron 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAPN15 calpain 15
CCR3 chemokine (C-C motif) receptor 3
CD38 CD38 molecule
CDC14A cell division cycle 14A
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH18 cadherin 18, type 2
CDK13 cyclin-dependent kinase 13
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHD4 chromodomain helicase DNA binding protein 4
CHD7 chromodomain helicase DNA binding protein 7
CHERP calcium homeostasis endoplasmic reticulum protein
CHM choroideremia (Rab escort protein 1)
CHSY1 chondroitin sulfate synthase 1
CHSY3 chondroitin sulfate synthase 3
CLCN5 chloride channel, voltage-sensitive 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNTNAP4 contactin associated protein-like 4
COA7 cytochrome c oxidase assembly factor 7 (putative)
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSAG1 chondrosarcoma associated gene 1
CTAG2 cancer/testis antigen 2
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCAF4 DDB1 and CUL4 associated factor 4
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2
DCLRE1B DNA cross-link repair 1B
DDHD1 DDHD domain containing 1
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DEFB125 defensin, beta 125
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DIEXF digestive organ expansion factor homolog (zebrafish)
DPH2 DPH2 homolog (S. cerevisiae)
DSCR4 Down syndrome critical region 4
DUSP18 dual specificity phosphatase 18
E2F5 E2F transcription factor 5, p130-binding
EFR3B EFR3 homolog B (S. cerevisiae)
EHD4 EH-domain containing 4
EID1 EP300 interacting inhibitor of differentiation 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF5A2 eukaryotic translation initiation factor 5A2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA3 EPH receptor A3
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERCC4 excision repair cross-complementation group 4
EXOSC6 exosome component 6
EXTL3 exostosin-like glycosyltransferase 3
FAM122C family with sequence similarity 122C
FAM133A family with sequence similarity 133, member A
FBXL18 F-box and leucine-rich repeat protein 18
FCAR Fc fragment of IgA receptor
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FER1L6 fer-1-like family member 6
FFAR3 free fatty acid receptor 3
FKBP14 FK506 binding protein 14, 22 kDa
FLJ25758 MAP/microtubule affinity-regulating kinase 1 pseudogene
FLJ30679 uncharacterized protein FLJ30679
FLNB filamin B, beta
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FTO fat mass and obesity associated
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
FZD3 frizzled class receptor 3
GALK2 galactokinase 2
GAREM GRB2 associated, regulator of MAPK1
GARS glycyl-tRNA synthetase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GCSH glycine cleavage system protein H (aminomethyl carrier)
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN5 gem (nuclear organelle) associated protein 5
GJB4 gap junction protein, beta 4, 30.3kDa
GLS glutaminase
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GPR176 G protein-coupled receptor 176
GREB1L growth regulation by estrogen in breast cancer-like
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRK4 G protein-coupled receptor kinase 4
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSPT1 G1 to S phase transition 1
GTSF1 gametocyte specific factor 1
HAS2 hyaluronan synthase 2
HAS2-AS1 HAS2 antisense RNA 1
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HEATR1 HEAT repeat containing 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis)
HHLA1 HERV-H LTR-associating 1
HOMER1 homer scaffolding protein 1
HOXC8 homeobox C8
HPDL 4-hydroxyphenylpyruvate dioxygenase-like
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTT huntingtin
IARS isoleucyl-tRNA synthetase
IBSP integrin-binding sialoprotein
IL17C interleukin 17C
IL36B interleukin 36, beta
IMPAD1 inositol monophosphatase domain containing 1
INGX inhibitor of growth family, X-linked, pseudogene
INS-IGF2 INS-IGF2 readthrough
INTS4P1 integrator complex subunit 4 pseudogene 1
INTS7 integrator complex subunit 7
IPO4 importin 4
IQCF5 IQ motif containing F5
IRF6 interferon regulatory factor 6
IRS1 insulin receptor substrate 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ISPD isoprenoid synthase domain containing
JPH4 junctophilin 4
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KDM1A lysine (K)-specific demethylase 1A
KDM5C lysine (K)-specific demethylase 5C
KIAA1551 KIAA1551
KIF23 kinesin family member 23
KLHL8 kelch-like family member 8
KLK14 kallikrein-related peptidase 14
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT77 keratin 77, type II
LACTB lactamase, beta
LARP4 La ribonucleoprotein domain family, member 4
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCMT2 leucine carboxyl methyltransferase 2
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LHX8 LIM homeobox 8
LIN28B lin-28 homolog B (C. elegans)
LINC00174 long intergenic non-protein coding RNA 174
LINC00239 long intergenic non-protein coding RNA 239
LINC00520 long intergenic non-protein coding RNA 520
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC283332 uncharacterized LOC283332
LOC392196 ubiquitin specific peptidase 17-like family member 2 pseudogene
LOC646999 akirin 1 pseudogene
LOC728819
LONP2 lon peptidase 2, peroxisomal
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRC3 leucine rich repeat containing 3
LRRC8A leucine rich repeat containing 8 family, member A
LRRC8C leucine rich repeat containing 8 family, member C
LRRC8E leucine rich repeat containing 8 family, member E
LTN1 listerin E3 ubiquitin protein ligase 1
LUZP1 leucine zipper protein 1
LUZP4 leucine zipper protein 4
LYAR Ly1 antibody reactive
MAB21L2 mab-21-like 2 (C. elegans)
MAGEA1 melanoma antigen family A1
MAGEA10 melanoma antigen family A10
MAGEA12 melanoma antigen family A12
MAGEA2 melanoma antigen family A2
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAGEA6 melanoma antigen family A6
MAGEA8 melanoma antigen family A8
MAGEA9B melanoma antigen family A9B
MAGEB1 melanoma antigen family B1
MAGEB16 melanoma antigen family B16
MAGEB2 melanoma antigen family B2
MAGEB6 melanoma antigen family B6
MAGEC1 melanoma antigen family C1
MAP1S microtubule-associated protein 1S
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MED14 mediator complex subunit 14
MEFV Mediterranean fever
MEOX1 mesenchyme homeobox 1
METTL13 methyltransferase like 13
MGC45800
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOCS3 molybdenum cofactor synthesis 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTFR1 mitochondrial fission regulator 1
MTMR9 myotubularin related protein 9
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO7B myosin VIIB
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACAD NAC alpha domain containing
NAF1 nuclear assembly factor 1 ribonucleoprotein
NBEAP1 neurobeachin pseudogene 1
NDC1 NDC1 transmembrane nucleoporin
NEU2 sialidase 2 (cytosolic sialidase)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NKRF NFKB repressing factor
NLRP10 NLR family, pyrin domain containing 10
NOD2 nucleotide-binding oligomerization domain containing 2
NOL6 nucleolar protein 6 (RNA-associated)
NOP14 NOP14 nucleolar protein
NPHP3-AS1 NPHP3 antisense RNA 1
NUP93 nucleoporin 93kDa
ODC1 ornithine decarboxylase 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR4F15 olfactory receptor, family 4, subfamily F, member 15
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR51B5 olfactory receptor, family 51, subfamily B, member 5
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAWR PRKC, apoptosis, WT1, regulator
PDCD11 programmed cell death 11
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PFAS phosphoribosylformylglycinamidine synthase
PGAM5 phosphoglycerate mutase family member 5
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLK1 polo-like kinase 1
PNMA1 paraneoplastic Ma antigen 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POMK protein-O-mannose kinase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU3F4 POU class 3 homeobox 4
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRDM9 PR domain containing 9
PRICKLE3 prickle homolog 3 (Drosophila)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT5 protein arginine methyltransferase 5
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPRE protein tyrosine phosphatase, receptor type, E
PURB purine-rich element binding protein B
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB35 RAB35, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBM12 RNA binding motif protein 12
RFTN1 raftlin, lipid raft linker 1
RHOF ras homolog family member F (in filopodia)
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPAP1 RNA polymerase II associated protein 1
RPTOR regulatory associated protein of MTOR, complex 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RXFP1 relaxin/insulin-like family peptide receptor 1
SAGE1 sarcoma antigen 1
SALL4 spalt-like transcription factor 4
SBNO1 strawberry notch homolog 1 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SF3B3 splicing factor 3b, subunit 3, 130kDa
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHF Src homology 2 domain containing F
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35G6 solute carrier family 35, member G6
SLC38A8 solute carrier family 38, member 8
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNORA58 small nucleolar RNA, H/ACA box 58
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SPATA31A1 SPATA31 subfamily A, member 1
SPATA31A3 SPATA31 subfamily A, member 3
SPATA31A6 SPATA31 subfamily A, member 6
SPESP1 sperm equatorial segment protein 1
SPRYD4 SPRY domain containing 4
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRRM4 serine/arginine repetitive matrix 4
ST20-AS1 ST20 antisense RNA 1
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBRG4 transforming growth factor beta regulator 4
TCP1 t-complex 1
TDG thymine-DNA glycosylase
TDO2 tryptophan 2,3-dioxygenase
TENM1 teneurin transmembrane protein 1
TEX10 testis expressed 10
TEX37 testis expressed 37
TGM2 transglutaminase 2
TGS1 trimethylguanosine synthase 1
THBS1 thrombospondin 1
TIGD1 tigger transposable element derived 1
TMEM135 transmembrane protein 135
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIB1 tribbles pseudokinase 1
TRIM58 tripartite motif containing 58
TRIM61 tripartite motif containing 61
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TSSK1B testis-specific serine kinase 1B
TTC27 tetratricopeptide repeat domain 27
TTLL4 tubulin tyrosine ligase-like family member 4
TXLNG taxilin gamma
UBA1 ubiquitin-like modifier activating enzyme 1
UBQLN2 ubiquilin 2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP10 ubiquitin specific peptidase 10
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP26 ubiquitin specific peptidase 26
USP3 ubiquitin specific peptidase 3
USP9X ubiquitin specific peptidase 9, X-linked
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VCL vinculin
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VN1R2 vomeronasal 1 receptor 2
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR43 WD repeat domain 43
WIZ widely interspaced zinc finger motifs
XPO6 exportin 6
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZCCHC12 zinc finger, CCHC domain containing 12
ZFP42 ZFP42 zinc finger protein
ZNF200 zinc finger protein 200
ZNF281 zinc finger protein 281
ZNF479 zinc finger protein 479
ZNF486 zinc finger protein 486
ZNF597 zinc finger protein 597
ZNF697 zinc finger protein 697
ZNF778 zinc finger protein 778
ZNF781 zinc finger protein 781

low expression

Symbol Name
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
SETD6 SET domain containing 6